EP0081976B1 - Durchstechbarer Verschluss für Probeflaschen - Google Patents
Durchstechbarer Verschluss für Probeflaschen Download PDFInfo
- Publication number
- EP0081976B1 EP0081976B1 EP82306556A EP82306556A EP0081976B1 EP 0081976 B1 EP0081976 B1 EP 0081976B1 EP 82306556 A EP82306556 A EP 82306556A EP 82306556 A EP82306556 A EP 82306556A EP 0081976 B1 EP0081976 B1 EP 0081976B1
- Authority
- EP
- European Patent Office
- Prior art keywords
- cap
- membrane
- wad
- sample container
- container according
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Images
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
- A61J1/00—Containers specially adapted for medical or pharmaceutical purposes
- A61J1/14—Details; Accessories therefor
- A61J1/1406—Septums, pierceable membranes
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
- B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
- B01L3/508—Containers for the purpose of retaining a material to be analysed, e.g. test tubes rigid containers not provided for above
- B01L3/5082—Test tubes per se
- B01L3/50825—Closing or opening means, corks, bungs
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
- B65D—CONTAINERS FOR STORAGE OR TRANSPORT OF ARTICLES OR MATERIALS, e.g. BAGS, BARRELS, BOTTLES, BOXES, CANS, CARTONS, CRATES, DRUMS, JARS, TANKS, HOPPERS, FORWARDING CONTAINERS; ACCESSORIES, CLOSURES, OR FITTINGS THEREFOR; PACKAGING ELEMENTS; PACKAGES
- B65D51/00—Closures not otherwise provided for
- B65D51/002—Closures to be pierced by an extracting-device for the contents and fixed on the container by separate retaining means
Definitions
- the invention relates to piercable closures for containers, particularly sterile or sterilisable containers for samples, usually blood, that may require pathological test and analysis.
- a closure in the form of a dished cap equipped with securement means relative to a sample container, say as a push-fit or via screw- threading of its side walling, and with the dished portion of the cap having an aperture clear through but closed by an added membrane of a non-elastomeric material, usually different from the cap, more readily pierced than any practical integral thinning of the cap material.
- a membrane that is between 0.02 mm and 0.50 mm in thickness and of a material and a specific thickness selected to afford practical combination of piercability, robustness and resistance to moisture and water vapour penetration or transmission.
- a relatively thick material in the above range usually, of course, has advantages, at least in robustness, compared with very thin and easily pierced membranes even where such are not subject to porosity or being left with holes therethrough, though the use of such membranes in practising this invention is not ruled out entirely.
- One suitable membrane material is aluminium foil, which we prefer to mount upon a washer-like base apertured to register with the cap aperture when fitted, and generally to form what we call a "wad".
- Another aspect of this invention concerns a wad for insertion as a seal into an apertured cap, the wad including an annular washer-like base member apertured to register with the cap aperture and having secured thereto an aperture- closing membrane that is readily piercable.
- the whole wad is such as to be clamped between a container mouth edge and the cap itself about the aperture of the latter.
- the membrane shall extend sufficiently, preferably fully, across the cap dishing. Then the membrane will either be engaged directly by all of the mouth edge of the container, or subjected to compressive clamping by the latter engaging on the base of the wad, depending on the attitude of the wad in the cap.
- the membrane should afford a liquid-tight seal and act as a suitable barrier against bacteria and water vapour. It is also desirable that the seal should not be subject to adherence problems when, as is required for blood samples, the container must be opened for addition of blood, usually to a suitable medium already in the container (e.g. sodium citrate), and reclosed/sealed pending subsequent piercing to sample for test purposes, usually in a pipette in a pathology laboratory.
- a suitable medium already in the container e.g. sodium citrate
- At least wads hereof can often be interference fits to the caps. However, wherever desired or required such wads, even membranes only, may be fixed into the cap using a suitable cement or adhesive, say of hot melt or impact types.
- hot melt adhesive leads us to another aspect hereof where an apertured cap is sealed simply with readily piercable solidified material, such as hot melt adhesive, in the aperture regardless of specific other leak proof features for the cap.
- a container 10 is shown screw- fitted with a dished cap 12 via internal threading of the side wall 14 of the cap mating at 16 with exterior threading of a neck portion 18 of the container below edge 22 of its mouth.
- the dished end portion 26 of the cap 12 has a e.g. centrally located aperture 28 clear through its thickness. Clamped between the interior of cap end 26, all about its aperture 28, and the container mouth edge 22 is a wad 30.
- the wad 30 comprises an annular washer-like base member 32, centrally apertured at 34 in register with the cap end aperture 28, and a membrane 36 covering that aperture 34.
- the membrane 36 comprises aluminium foil affixed to base member 32 either directly by a suitable adhesive as indicated for an expanded polythene base, or via a paper backing (not shown, but often advisable for certain wad materials, such as woodpulp board).
- the base member 32 is engaged all round by the container mouth edge 22 for desired sealing, in fact abuts substantially entirely to the periphery of the inner surface of the cap end portion 26.
- the wad needs only to be pressed into place, usually as an interference fit (push-fit), though it could be adheringly secured by a suitable adhesive or cement if preferred or required.
- the membrane 36 is shown extending entirely across the base member 32, including its aperture, and is subjected to edge compression through the base by action of the container mouth edge 22 to reduce risk of delimination. It is feasible to use the wad inverted so that the membrane contacts the container mouth edge, so long as a satisfactory seal results, and paper-backing of aluminium or other foil can assist both securement and sealing.
- the complete wad is made as a unit, i.e. the base member 32 and the membrane 36 affixed securely together. Any suitable adhesive or cement can be used or they may simply be hot-pressed together where waxed backing paper is used for the membrane foil.
- the base member 32 of the wad 30 assists in assuring compressive obtainment of a readily broken and reattained liquid seal.
- Unpreferred, but practical, possibilities arise by way of relying only upon a membrane, perhaps preferably backed, secured directly to the inner surface of the cap, maybe even not fully coextensive therewith, nor sealing to the container mouth edge, or the latter and the cap are mutually formed to seal together without interposition of a barrier foil or film.
- Adhesives based on synthetic resins are suitable, for example polyvinyl acetate. Heat sensitive adhesives are preferred for adhering membranes to wad bases. At least hot melt adhesives may even allow membranes to be dispensed with, relying instead simply on a plug of settable but readily pierced material on the cap aperture.
- Lamination of foil to a paper backing if used is conveniently by way of synthetic latex adhesives applied hot or cold, but normally using heat in the laminating process to accelerate curing.
Claims (9)
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
AT82306556T ATE14847T1 (de) | 1981-12-11 | 1982-12-08 | Durchstechbarer verschluss fuer probeflaschen. |
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB8137467 | 1981-12-11 | ||
GB8137467 | 1981-12-11 |
Publications (2)
Publication Number | Publication Date |
---|---|
EP0081976A1 EP0081976A1 (de) | 1983-06-22 |
EP0081976B1 true EP0081976B1 (de) | 1985-08-14 |
Family
ID=10526547
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
EP82306556A Expired EP0081976B1 (de) | 1981-12-11 | 1982-12-08 | Durchstechbarer Verschluss für Probeflaschen |
Country Status (5)
Country | Link |
---|---|
EP (1) | EP0081976B1 (de) |
AT (1) | ATE14847T1 (de) |
AU (1) | AU9130382A (de) |
DE (1) | DE3265463D1 (de) |
DK (1) | DK545182A (de) |
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6495195B2 (en) | 1997-02-14 | 2002-12-17 | Arcturus Engineering, Inc. | Broadband absorbing film for laser capture microdissection |
US7691332B2 (en) | 2001-03-09 | 2010-04-06 | Gen-Probe Incorporated | Penetrable cap |
Families Citing this family (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB2162158A (en) * | 1984-04-13 | 1986-01-29 | Donald Paul Pilla | Closure |
JPH02212768A (ja) * | 1989-02-13 | 1990-08-23 | Terumo Corp | 採液管 |
IT215743Z2 (it) * | 1989-03-03 | 1990-11-05 | Instrumentation Lab Spa | Cuvetta per campioni con tappo saldato. |
JP2923302B2 (ja) * | 1989-05-17 | 1999-07-26 | テルモ株式会社 | 隔膜付き管状体 |
GB2234742A (en) * | 1989-08-11 | 1991-02-13 | Inibsa Lab | A bottle for renal dialysis |
US5253774A (en) * | 1992-06-26 | 1993-10-19 | Bio-Rad Laboratories, Inc. | Reagent receptacle and support rack for automated clinical analyzers |
ES2334890T3 (es) * | 1993-10-22 | 2010-03-17 | Abbott Laboratories | Tubo de reaccion y metodo de uso para minimizar la contaminacion. |
US5859699A (en) * | 1997-02-07 | 1999-01-12 | Arcturus Engineering, Inc. | Laser capture microdissection analysis vessel |
EP1181980A1 (de) * | 2000-08-24 | 2002-02-27 | TTP LabTech Ltd | Flüssigkeitsspeicherung |
GB2493389A (en) * | 2011-08-05 | 2013-02-06 | Closures Ltd | Cap and Method for Sealing a Drink Container |
Family Cites Families (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
BE438801A (de) * | ||||
CH147396A (de) * | 1930-06-17 | 1931-06-15 | Zuercher Gottlieb | Abschlussvorrichtung an Versandflaschen für Flüssigkeiten. |
US2099370A (en) * | 1935-09-07 | 1937-11-16 | Monnier Vital | Phial |
GB766778A (en) * | 1954-05-25 | 1957-01-23 | Glaxo Lab Ltd | Improvements in or relating to closures for bottles, jars, vials and like containers |
DE2051581A1 (de) * | 1970-10-21 | 1972-05-04 | Freienstein, Christoph, 6900 Heidelberg | Deckelraster zum vereinfachten Schließen und Öffnen mehrerer Probefläschchen, Reagenzgläser etc |
FR2110778A5 (de) * | 1970-10-30 | 1972-06-02 | Alca Sa | |
GB1468801A (en) * | 1973-03-07 | 1977-03-30 | Accu Tech Ltd | Containers |
US4094460A (en) * | 1976-04-26 | 1978-06-13 | Aluminum Company Of America | Closure assembly and package |
-
1982
- 1982-12-07 AU AU91303/82A patent/AU9130382A/en not_active Abandoned
- 1982-12-08 DK DK545182A patent/DK545182A/da not_active Application Discontinuation
- 1982-12-08 AT AT82306556T patent/ATE14847T1/de not_active IP Right Cessation
- 1982-12-08 DE DE8282306556T patent/DE3265463D1/de not_active Expired
- 1982-12-08 EP EP82306556A patent/EP0081976B1/de not_active Expired
Cited By (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6495195B2 (en) | 1997-02-14 | 2002-12-17 | Arcturus Engineering, Inc. | Broadband absorbing film for laser capture microdissection |
US7691332B2 (en) | 2001-03-09 | 2010-04-06 | Gen-Probe Incorporated | Penetrable cap |
US7824922B2 (en) | 2001-03-09 | 2010-11-02 | Gen-Probe Incorporated | Method for removing a fluid substance from a closed system |
US8052944B2 (en) | 2001-03-09 | 2011-11-08 | Gen-Probe Incorporated | Penetrable cap |
US8057762B2 (en) | 2001-03-09 | 2011-11-15 | Gen-Probe Incorporated | Penetrable cap |
US8685347B2 (en) | 2001-03-09 | 2014-04-01 | Gen-Probe Incorporated | Penetrable cap |
USRE45194E1 (en) | 2001-03-09 | 2014-10-14 | Gen-Probe Incorporated | Penetrable cap |
Also Published As
Publication number | Publication date |
---|---|
ATE14847T1 (de) | 1985-08-15 |
DE3265463D1 (en) | 1985-09-19 |
DK545182A (da) | 1983-06-12 |
EP0081976A1 (de) | 1983-06-22 |
AU9130382A (en) | 1983-06-16 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
EP0081976B1 (de) | Durchstechbarer Verschluss für Probeflaschen | |
US5433716A (en) | Safety closing device for biological liquid containers | |
US5061263A (en) | Liquid collection tube | |
CA2065925C (en) | Container seal with a sealing body which can be punctured | |
US3951331A (en) | Reclosable closure | |
US6669908B2 (en) | Urine test device | |
US5897840A (en) | Multi-chambered urine specimen container for automatic extraction and high forensic integrity | |
CA1234770A (en) | Biological sampling tube | |
FI93398B (fi) | Analyyttinen testiliuska | |
US8132685B2 (en) | Two-part closure for a container | |
US3580423A (en) | Container closure and apparatus for opening same | |
JPS61170437A (ja) | 採血管 | |
US20070183937A1 (en) | Specimen tube with piercable end cap | |
EP0385759A3 (de) | Hochtemperatur-Hochdruck-Zersetzungsbehälterzusammenbau | |
US5326534A (en) | Liquid collection tube | |
JPH09110077A (ja) | 振り出し用紙容器 | |
US4880425A (en) | Blood bag having label providing enhanced gas transmissibility | |
ES538969A0 (es) | Tapon farmaceutico, piston o similar y procedimiento para su obtencion. | |
AU2005209675B2 (en) | Two-part closure for a container | |
JPH09323377A (ja) | 易突き刺し性を有する蓋材 | |
JP3030824B2 (ja) | キャップ構造 | |
JPH0377541A (ja) | 採液容器 | |
KR900007570Y1 (ko) | 수액(輸液)용기용 커버캡 붙임 마개체 | |
US4741451A (en) | Easy open container | |
JPH0319877Y2 (de) |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
PUAI | Public reference made under article 153(3) epc to a published international application that has entered the european phase |
Free format text: ORIGINAL CODE: 0009012 |
|
AK | Designated contracting states |
Designated state(s): AT BE CH DE FR GB IT LI LU NL SE |
|
17P | Request for examination filed |
Effective date: 19830624 |
|
ITF | It: translation for a ep patent filed |
Owner name: LENZI & C. |
|
GRAA | (expected) grant |
Free format text: ORIGINAL CODE: 0009210 |
|
AK | Designated contracting states |
Designated state(s): AT BE CH DE FR GB IT LI LU NL SE |
|
PG25 | Lapsed in a contracting state [announced via postgrant information from national office to epo] |
Ref country code: AT Effective date: 19850814 |
|
REF | Corresponds to: |
Ref document number: 14847 Country of ref document: AT Date of ref document: 19850815 Kind code of ref document: T |
|
PG25 | Lapsed in a contracting state [announced via postgrant information from national office to epo] |
Ref country code: SE Effective date: 19850830 |
|
REF | Corresponds to: |
Ref document number: 3265463 Country of ref document: DE Date of ref document: 19850919 |
|
ET | Fr: translation filed | ||
PG25 | Lapsed in a contracting state [announced via postgrant information from national office to epo] |
Ref country code: LU Free format text: LAPSE BECAUSE OF NON-PAYMENT OF DUE FEES Effective date: 19851231 |
|
PLBE | No opposition filed within time limit |
Free format text: ORIGINAL CODE: 0009261 |
|
STAA | Information on the status of an ep patent application or granted ep patent |
Free format text: STATUS: NO OPPOSITION FILED WITHIN TIME LIMIT |
|
26N | No opposition filed | ||
PGFP | Annual fee paid to national office [announced via postgrant information from national office to epo] |
Ref country code: NL Payment date: 19871231 Year of fee payment: 6 |
|
PGFP | Annual fee paid to national office [announced via postgrant information from national office to epo] |
Ref country code: FR Payment date: 19881228 Year of fee payment: 7 |
|
ITTA | It: last paid annual fee | ||
PGFP | Annual fee paid to national office [announced via postgrant information from national office to epo] |
Ref country code: DE Payment date: 19890131 Year of fee payment: 7 |
|
PG25 | Lapsed in a contracting state [announced via postgrant information from national office to epo] |
Ref country code: LI Effective date: 19891231 Ref country code: CH Effective date: 19891231 Ref country code: BE Effective date: 19891231 |
|
BERE | Be: lapsed |
Owner name: STERILIN LTD Effective date: 19891231 |
|
PG25 | Lapsed in a contracting state [announced via postgrant information from national office to epo] |
Ref country code: NL Effective date: 19900701 |
|
NLV4 | Nl: lapsed or anulled due to non-payment of the annual fee | ||
PG25 | Lapsed in a contracting state [announced via postgrant information from national office to epo] |
Ref country code: FR Effective date: 19900831 |
|
REG | Reference to a national code |
Ref country code: CH Ref legal event code: PL |
|
PG25 | Lapsed in a contracting state [announced via postgrant information from national office to epo] |
Ref country code: DE Effective date: 19900901 |
|
REG | Reference to a national code |
Ref country code: FR Ref legal event code: ST |
|
REG | Reference to a national code |
Ref country code: GB Ref legal event code: 732E |
|
PGFP | Annual fee paid to national office [announced via postgrant information from national office to epo] |
Ref country code: GB Payment date: 19961129 Year of fee payment: 15 |
|
PG25 | Lapsed in a contracting state [announced via postgrant information from national office to epo] |
Ref country code: GB Free format text: LAPSE BECAUSE OF NON-PAYMENT OF DUE FEES Effective date: 19971208 |
|
GBPC | Gb: european patent ceased through non-payment of renewal fee |
Effective date: 19971208 |