EP0069768A4 - ONE-PIECE CONNECTORS AND STERILE CONNECTING SYSTEM. - Google Patents

ONE-PIECE CONNECTORS AND STERILE CONNECTING SYSTEM.

Info

Publication number
EP0069768A4
EP0069768A4 EP19820900696 EP82900696A EP0069768A4 EP 0069768 A4 EP0069768 A4 EP 0069768A4 EP 19820900696 EP19820900696 EP 19820900696 EP 82900696 A EP82900696 A EP 82900696A EP 0069768 A4 EP0069768 A4 EP 0069768A4
Authority
EP
European Patent Office
Prior art keywords
wall
housing
opaque
transparent
sterile
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP19820900696
Other languages
German (de)
English (en)
French (fr)
Other versions
EP0069768A1 (en
Inventor
Robert J Kruger
Daniel B Granzow
Daniel R Boggs
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Baxter International Inc
Original Assignee
Baxter Travenol Laboratories Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Baxter Travenol Laboratories Inc filed Critical Baxter Travenol Laboratories Inc
Publication of EP0069768A1 publication Critical patent/EP0069768A1/en
Publication of EP0069768A4 publication Critical patent/EP0069768A4/en
Withdrawn legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M39/00Tubes, tube connectors, tube couplings, valves, access sites or the like, specially adapted for medical use
    • A61M39/10Tube connectors; Tube couplings
    • A61M39/14Tube connectors; Tube couplings for connecting tubes having sealed ends
    • A61M39/143Tube connectors; Tube couplings for connecting tubes having sealed ends both tube ends being sealed by meltable membranes pierced after connection by use of heat, e.g. using radiant energy
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B29WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
    • B29CSHAPING OR JOINING OF PLASTICS; SHAPING OF MATERIAL IN A PLASTIC STATE, NOT OTHERWISE PROVIDED FOR; AFTER-TREATMENT OF THE SHAPED PRODUCTS, e.g. REPAIRING
    • B29C65/00Joining or sealing of preformed parts, e.g. welding of plastics materials; Apparatus therefor
    • B29C65/02Joining or sealing of preformed parts, e.g. welding of plastics materials; Apparatus therefor by heating, with or without pressure
    • B29C65/14Joining or sealing of preformed parts, e.g. welding of plastics materials; Apparatus therefor by heating, with or without pressure using wave energy, i.e. electromagnetic radiation, or particle radiation
    • B29C65/1429Joining or sealing of preformed parts, e.g. welding of plastics materials; Apparatus therefor by heating, with or without pressure using wave energy, i.e. electromagnetic radiation, or particle radiation characterised by the way of heating the interface
    • B29C65/1435Joining or sealing of preformed parts, e.g. welding of plastics materials; Apparatus therefor by heating, with or without pressure using wave energy, i.e. electromagnetic radiation, or particle radiation characterised by the way of heating the interface at least passing through one of the parts to be joined, i.e. transmission welding
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B29WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
    • B29CSHAPING OR JOINING OF PLASTICS; SHAPING OF MATERIAL IN A PLASTIC STATE, NOT OTHERWISE PROVIDED FOR; AFTER-TREATMENT OF THE SHAPED PRODUCTS, e.g. REPAIRING
    • B29C65/00Joining or sealing of preformed parts, e.g. welding of plastics materials; Apparatus therefor
    • B29C65/02Joining or sealing of preformed parts, e.g. welding of plastics materials; Apparatus therefor by heating, with or without pressure
    • B29C65/14Joining or sealing of preformed parts, e.g. welding of plastics materials; Apparatus therefor by heating, with or without pressure using wave energy, i.e. electromagnetic radiation, or particle radiation
    • B29C65/1477Joining or sealing of preformed parts, e.g. welding of plastics materials; Apparatus therefor by heating, with or without pressure using wave energy, i.e. electromagnetic radiation, or particle radiation making use of an absorber or impact modifier
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B29WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
    • B29CSHAPING OR JOINING OF PLASTICS; SHAPING OF MATERIAL IN A PLASTIC STATE, NOT OTHERWISE PROVIDED FOR; AFTER-TREATMENT OF THE SHAPED PRODUCTS, e.g. REPAIRING
    • B29C65/00Joining or sealing of preformed parts, e.g. welding of plastics materials; Apparatus therefor
    • B29C65/74Joining or sealing of preformed parts, e.g. welding of plastics materials; Apparatus therefor by welding and severing, or by joining and severing, the severing being performed in the area to be joined, next to the area to be joined, in the joint area or next to the joint area
    • B29C65/747Joining or sealing of preformed parts, e.g. welding of plastics materials; Apparatus therefor by welding and severing, or by joining and severing, the severing being performed in the area to be joined, next to the area to be joined, in the joint area or next to the joint area using other than mechanical means
    • B29C65/7473Joining or sealing of preformed parts, e.g. welding of plastics materials; Apparatus therefor by welding and severing, or by joining and severing, the severing being performed in the area to be joined, next to the area to be joined, in the joint area or next to the joint area using other than mechanical means using radiation, e.g. laser, for simultaneously welding and severing
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B29WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
    • B29CSHAPING OR JOINING OF PLASTICS; SHAPING OF MATERIAL IN A PLASTIC STATE, NOT OTHERWISE PROVIDED FOR; AFTER-TREATMENT OF THE SHAPED PRODUCTS, e.g. REPAIRING
    • B29C66/00General aspects of processes or apparatus for joining preformed parts
    • B29C66/01General aspects dealing with the joint area or with the area to be joined
    • B29C66/05Particular design of joint configurations
    • B29C66/10Particular design of joint configurations particular design of the joint cross-sections
    • B29C66/12Joint cross-sections combining only two joint-segments; Tongue and groove joints; Tenon and mortise joints; Stepped joint cross-sections
    • B29C66/128Stepped joint cross-sections
    • B29C66/1282Stepped joint cross-sections comprising at least one overlap joint-segment
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B29WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
    • B29CSHAPING OR JOINING OF PLASTICS; SHAPING OF MATERIAL IN A PLASTIC STATE, NOT OTHERWISE PROVIDED FOR; AFTER-TREATMENT OF THE SHAPED PRODUCTS, e.g. REPAIRING
    • B29C66/00General aspects of processes or apparatus for joining preformed parts
    • B29C66/01General aspects dealing with the joint area or with the area to be joined
    • B29C66/05Particular design of joint configurations
    • B29C66/10Particular design of joint configurations particular design of the joint cross-sections
    • B29C66/12Joint cross-sections combining only two joint-segments; Tongue and groove joints; Tenon and mortise joints; Stepped joint cross-sections
    • B29C66/128Stepped joint cross-sections
    • B29C66/1284Stepped joint cross-sections comprising at least one butt joint-segment
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B29WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
    • B29CSHAPING OR JOINING OF PLASTICS; SHAPING OF MATERIAL IN A PLASTIC STATE, NOT OTHERWISE PROVIDED FOR; AFTER-TREATMENT OF THE SHAPED PRODUCTS, e.g. REPAIRING
    • B29C66/00General aspects of processes or apparatus for joining preformed parts
    • B29C66/01General aspects dealing with the joint area or with the area to be joined
    • B29C66/05Particular design of joint configurations
    • B29C66/10Particular design of joint configurations particular design of the joint cross-sections
    • B29C66/12Joint cross-sections combining only two joint-segments; Tongue and groove joints; Tenon and mortise joints; Stepped joint cross-sections
    • B29C66/128Stepped joint cross-sections
    • B29C66/1286Stepped joint cross-sections comprising at least one bevelled joint-segment
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B29WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
    • B29CSHAPING OR JOINING OF PLASTICS; SHAPING OF MATERIAL IN A PLASTIC STATE, NOT OTHERWISE PROVIDED FOR; AFTER-TREATMENT OF THE SHAPED PRODUCTS, e.g. REPAIRING
    • B29C66/00General aspects of processes or apparatus for joining preformed parts
    • B29C66/01General aspects dealing with the joint area or with the area to be joined
    • B29C66/05Particular design of joint configurations
    • B29C66/10Particular design of joint configurations particular design of the joint cross-sections
    • B29C66/13Single flanged joints; Fin-type joints; Single hem joints; Edge joints; Interpenetrating fingered joints; Other specific particular designs of joint cross-sections not provided for in groups B29C66/11 - B29C66/12
    • B29C66/131Single flanged joints, i.e. one of the parts to be joined being rigid and flanged in the joint area
    • B29C66/1312Single flange to flange joints, the parts to be joined being rigid
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B29WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
    • B29CSHAPING OR JOINING OF PLASTICS; SHAPING OF MATERIAL IN A PLASTIC STATE, NOT OTHERWISE PROVIDED FOR; AFTER-TREATMENT OF THE SHAPED PRODUCTS, e.g. REPAIRING
    • B29C66/00General aspects of processes or apparatus for joining preformed parts
    • B29C66/50General aspects of joining tubular articles; General aspects of joining long products, i.e. bars or profiled elements; General aspects of joining single elements to tubular articles, hollow articles or bars; General aspects of joining several hollow-preforms to form hollow or tubular articles
    • B29C66/51Joining tubular articles, profiled elements or bars; Joining single elements to tubular articles, hollow articles or bars; Joining several hollow-preforms to form hollow or tubular articles
    • B29C66/52Joining tubular articles, bars or profiled elements
    • B29C66/522Joining tubular articles
    • B29C66/5221Joining tubular articles for forming coaxial connections, i.e. the tubular articles to be joined forming a zero angle relative to each other
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B29WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
    • B29CSHAPING OR JOINING OF PLASTICS; SHAPING OF MATERIAL IN A PLASTIC STATE, NOT OTHERWISE PROVIDED FOR; AFTER-TREATMENT OF THE SHAPED PRODUCTS, e.g. REPAIRING
    • B29C66/00General aspects of processes or apparatus for joining preformed parts
    • B29C66/50General aspects of joining tubular articles; General aspects of joining long products, i.e. bars or profiled elements; General aspects of joining single elements to tubular articles, hollow articles or bars; General aspects of joining several hollow-preforms to form hollow or tubular articles
    • B29C66/51Joining tubular articles, profiled elements or bars; Joining single elements to tubular articles, hollow articles or bars; Joining several hollow-preforms to form hollow or tubular articles
    • B29C66/52Joining tubular articles, bars or profiled elements
    • B29C66/522Joining tubular articles
    • B29C66/5229Joining tubular articles involving the use of a socket
    • B29C66/52291Joining tubular articles involving the use of a socket said socket comprising a stop
    • B29C66/52293Joining tubular articles involving the use of a socket said socket comprising a stop said stop being external
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B29WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
    • B29CSHAPING OR JOINING OF PLASTICS; SHAPING OF MATERIAL IN A PLASTIC STATE, NOT OTHERWISE PROVIDED FOR; AFTER-TREATMENT OF THE SHAPED PRODUCTS, e.g. REPAIRING
    • B29C66/00General aspects of processes or apparatus for joining preformed parts
    • B29C66/50General aspects of joining tubular articles; General aspects of joining long products, i.e. bars or profiled elements; General aspects of joining single elements to tubular articles, hollow articles or bars; General aspects of joining several hollow-preforms to form hollow or tubular articles
    • B29C66/51Joining tubular articles, profiled elements or bars; Joining single elements to tubular articles, hollow articles or bars; Joining several hollow-preforms to form hollow or tubular articles
    • B29C66/52Joining tubular articles, bars or profiled elements
    • B29C66/522Joining tubular articles
    • B29C66/5229Joining tubular articles involving the use of a socket
    • B29C66/52298Joining tubular articles involving the use of a socket said socket being composed by several elements
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B29WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
    • B29CSHAPING OR JOINING OF PLASTICS; SHAPING OF MATERIAL IN A PLASTIC STATE, NOT OTHERWISE PROVIDED FOR; AFTER-TREATMENT OF THE SHAPED PRODUCTS, e.g. REPAIRING
    • B29C66/00General aspects of processes or apparatus for joining preformed parts
    • B29C66/50General aspects of joining tubular articles; General aspects of joining long products, i.e. bars or profiled elements; General aspects of joining single elements to tubular articles, hollow articles or bars; General aspects of joining several hollow-preforms to form hollow or tubular articles
    • B29C66/51Joining tubular articles, profiled elements or bars; Joining single elements to tubular articles, hollow articles or bars; Joining several hollow-preforms to form hollow or tubular articles
    • B29C66/54Joining several hollow-preforms, e.g. half-shells, to form hollow articles, e.g. for making balls, containers; Joining several hollow-preforms, e.g. half-cylinders, to form tubular articles
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B29WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
    • B29CSHAPING OR JOINING OF PLASTICS; SHAPING OF MATERIAL IN A PLASTIC STATE, NOT OTHERWISE PROVIDED FOR; AFTER-TREATMENT OF THE SHAPED PRODUCTS, e.g. REPAIRING
    • B29C66/00General aspects of processes or apparatus for joining preformed parts
    • B29C66/70General aspects of processes or apparatus for joining preformed parts characterised by the composition, physical properties or the structure of the material of the parts to be joined; Joining with non-plastics material
    • B29C66/73General aspects of processes or apparatus for joining preformed parts characterised by the composition, physical properties or the structure of the material of the parts to be joined; Joining with non-plastics material characterised by the intensive physical properties of the material of the parts to be joined, by the optical properties of the material of the parts to be joined, by the extensive physical properties of the parts to be joined, by the state of the material of the parts to be joined or by the material of the parts to be joined being a thermoplastic or a thermoset
    • B29C66/731General aspects of processes or apparatus for joining preformed parts characterised by the composition, physical properties or the structure of the material of the parts to be joined; Joining with non-plastics material characterised by the intensive physical properties of the material of the parts to be joined, by the optical properties of the material of the parts to be joined, by the extensive physical properties of the parts to be joined, by the state of the material of the parts to be joined or by the material of the parts to be joined being a thermoplastic or a thermoset characterised by the intensive physical properties of the material of the parts to be joined
    • B29C66/7311Thermal properties
    • B29C66/73115Melting point
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B29WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
    • B29CSHAPING OR JOINING OF PLASTICS; SHAPING OF MATERIAL IN A PLASTIC STATE, NOT OTHERWISE PROVIDED FOR; AFTER-TREATMENT OF THE SHAPED PRODUCTS, e.g. REPAIRING
    • B29C66/00General aspects of processes or apparatus for joining preformed parts
    • B29C66/70General aspects of processes or apparatus for joining preformed parts characterised by the composition, physical properties or the structure of the material of the parts to be joined; Joining with non-plastics material
    • B29C66/73General aspects of processes or apparatus for joining preformed parts characterised by the composition, physical properties or the structure of the material of the parts to be joined; Joining with non-plastics material characterised by the intensive physical properties of the material of the parts to be joined, by the optical properties of the material of the parts to be joined, by the extensive physical properties of the parts to be joined, by the state of the material of the parts to be joined or by the material of the parts to be joined being a thermoplastic or a thermoset
    • B29C66/733General aspects of processes or apparatus for joining preformed parts characterised by the composition, physical properties or the structure of the material of the parts to be joined; Joining with non-plastics material characterised by the intensive physical properties of the material of the parts to be joined, by the optical properties of the material of the parts to be joined, by the extensive physical properties of the parts to be joined, by the state of the material of the parts to be joined or by the material of the parts to be joined being a thermoplastic or a thermoset characterised by the optical properties of the material of the parts to be joined, e.g. fluorescence, phosphorescence
    • B29C66/7336General aspects of processes or apparatus for joining preformed parts characterised by the composition, physical properties or the structure of the material of the parts to be joined; Joining with non-plastics material characterised by the intensive physical properties of the material of the parts to be joined, by the optical properties of the material of the parts to be joined, by the extensive physical properties of the parts to be joined, by the state of the material of the parts to be joined or by the material of the parts to be joined being a thermoplastic or a thermoset characterised by the optical properties of the material of the parts to be joined, e.g. fluorescence, phosphorescence at least one of the parts to be joined being opaque, transparent or translucent to visible light
    • B29C66/73361General aspects of processes or apparatus for joining preformed parts characterised by the composition, physical properties or the structure of the material of the parts to be joined; Joining with non-plastics material characterised by the intensive physical properties of the material of the parts to be joined, by the optical properties of the material of the parts to be joined, by the extensive physical properties of the parts to be joined, by the state of the material of the parts to be joined or by the material of the parts to be joined being a thermoplastic or a thermoset characterised by the optical properties of the material of the parts to be joined, e.g. fluorescence, phosphorescence at least one of the parts to be joined being opaque, transparent or translucent to visible light at least one of the parts to be joined being opaque to visible light
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B29WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
    • B29CSHAPING OR JOINING OF PLASTICS; SHAPING OF MATERIAL IN A PLASTIC STATE, NOT OTHERWISE PROVIDED FOR; AFTER-TREATMENT OF THE SHAPED PRODUCTS, e.g. REPAIRING
    • B29C66/00General aspects of processes or apparatus for joining preformed parts
    • B29C66/70General aspects of processes or apparatus for joining preformed parts characterised by the composition, physical properties or the structure of the material of the parts to be joined; Joining with non-plastics material
    • B29C66/73General aspects of processes or apparatus for joining preformed parts characterised by the composition, physical properties or the structure of the material of the parts to be joined; Joining with non-plastics material characterised by the intensive physical properties of the material of the parts to be joined, by the optical properties of the material of the parts to be joined, by the extensive physical properties of the parts to be joined, by the state of the material of the parts to be joined or by the material of the parts to be joined being a thermoplastic or a thermoset
    • B29C66/733General aspects of processes or apparatus for joining preformed parts characterised by the composition, physical properties or the structure of the material of the parts to be joined; Joining with non-plastics material characterised by the intensive physical properties of the material of the parts to be joined, by the optical properties of the material of the parts to be joined, by the extensive physical properties of the parts to be joined, by the state of the material of the parts to be joined or by the material of the parts to be joined being a thermoplastic or a thermoset characterised by the optical properties of the material of the parts to be joined, e.g. fluorescence, phosphorescence
    • B29C66/7336General aspects of processes or apparatus for joining preformed parts characterised by the composition, physical properties or the structure of the material of the parts to be joined; Joining with non-plastics material characterised by the intensive physical properties of the material of the parts to be joined, by the optical properties of the material of the parts to be joined, by the extensive physical properties of the parts to be joined, by the state of the material of the parts to be joined or by the material of the parts to be joined being a thermoplastic or a thermoset characterised by the optical properties of the material of the parts to be joined, e.g. fluorescence, phosphorescence at least one of the parts to be joined being opaque, transparent or translucent to visible light
    • B29C66/73365General aspects of processes or apparatus for joining preformed parts characterised by the composition, physical properties or the structure of the material of the parts to be joined; Joining with non-plastics material characterised by the intensive physical properties of the material of the parts to be joined, by the optical properties of the material of the parts to be joined, by the extensive physical properties of the parts to be joined, by the state of the material of the parts to be joined or by the material of the parts to be joined being a thermoplastic or a thermoset characterised by the optical properties of the material of the parts to be joined, e.g. fluorescence, phosphorescence at least one of the parts to be joined being opaque, transparent or translucent to visible light at least one of the parts to be joined being transparent or translucent to visible light
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B29WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
    • B29CSHAPING OR JOINING OF PLASTICS; SHAPING OF MATERIAL IN A PLASTIC STATE, NOT OTHERWISE PROVIDED FOR; AFTER-TREATMENT OF THE SHAPED PRODUCTS, e.g. REPAIRING
    • B29C66/00General aspects of processes or apparatus for joining preformed parts
    • B29C66/70General aspects of processes or apparatus for joining preformed parts characterised by the composition, physical properties or the structure of the material of the parts to be joined; Joining with non-plastics material
    • B29C66/73General aspects of processes or apparatus for joining preformed parts characterised by the composition, physical properties or the structure of the material of the parts to be joined; Joining with non-plastics material characterised by the intensive physical properties of the material of the parts to be joined, by the optical properties of the material of the parts to be joined, by the extensive physical properties of the parts to be joined, by the state of the material of the parts to be joined or by the material of the parts to be joined being a thermoplastic or a thermoset
    • B29C66/739General aspects of processes or apparatus for joining preformed parts characterised by the composition, physical properties or the structure of the material of the parts to be joined; Joining with non-plastics material characterised by the intensive physical properties of the material of the parts to be joined, by the optical properties of the material of the parts to be joined, by the extensive physical properties of the parts to be joined, by the state of the material of the parts to be joined or by the material of the parts to be joined being a thermoplastic or a thermoset characterised by the material of the parts to be joined being a thermoplastic or a thermoset
    • B29C66/7392General aspects of processes or apparatus for joining preformed parts characterised by the composition, physical properties or the structure of the material of the parts to be joined; Joining with non-plastics material characterised by the intensive physical properties of the material of the parts to be joined, by the optical properties of the material of the parts to be joined, by the extensive physical properties of the parts to be joined, by the state of the material of the parts to be joined or by the material of the parts to be joined being a thermoplastic or a thermoset characterised by the material of the parts to be joined being a thermoplastic or a thermoset characterised by the material of at least one of the parts being a thermoplastic
    • B29C66/73921General aspects of processes or apparatus for joining preformed parts characterised by the composition, physical properties or the structure of the material of the parts to be joined; Joining with non-plastics material characterised by the intensive physical properties of the material of the parts to be joined, by the optical properties of the material of the parts to be joined, by the extensive physical properties of the parts to be joined, by the state of the material of the parts to be joined or by the material of the parts to be joined being a thermoplastic or a thermoset characterised by the material of the parts to be joined being a thermoplastic or a thermoset characterised by the material of at least one of the parts being a thermoplastic characterised by the materials of both parts being thermoplastics
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B29WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
    • B29CSHAPING OR JOINING OF PLASTICS; SHAPING OF MATERIAL IN A PLASTIC STATE, NOT OTHERWISE PROVIDED FOR; AFTER-TREATMENT OF THE SHAPED PRODUCTS, e.g. REPAIRING
    • B29C66/00General aspects of processes or apparatus for joining preformed parts
    • B29C66/80General aspects of machine operations or constructions and parts thereof
    • B29C66/84Specific machine types or machines suitable for specific applications
    • B29C66/857Medical tube welding machines
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B29WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
    • B29CSHAPING OR JOINING OF PLASTICS; SHAPING OF MATERIAL IN A PLASTIC STATE, NOT OTHERWISE PROVIDED FOR; AFTER-TREATMENT OF THE SHAPED PRODUCTS, e.g. REPAIRING
    • B29C66/00General aspects of processes or apparatus for joining preformed parts
    • B29C66/90Measuring or controlling the joining process
    • B29C66/91Measuring or controlling the joining process by measuring or controlling the temperature, the heat or the thermal flux
    • B29C66/914Measuring or controlling the joining process by measuring or controlling the temperature, the heat or the thermal flux by controlling or regulating the temperature, the heat or the thermal flux
    • B29C66/9141Measuring or controlling the joining process by measuring or controlling the temperature, the heat or the thermal flux by controlling or regulating the temperature, the heat or the thermal flux by controlling or regulating the temperature
    • B29C66/91411Measuring or controlling the joining process by measuring or controlling the temperature, the heat or the thermal flux by controlling or regulating the temperature, the heat or the thermal flux by controlling or regulating the temperature of the parts to be joined, e.g. the joining process taking the temperature of the parts to be joined into account
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B29WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
    • B29CSHAPING OR JOINING OF PLASTICS; SHAPING OF MATERIAL IN A PLASTIC STATE, NOT OTHERWISE PROVIDED FOR; AFTER-TREATMENT OF THE SHAPED PRODUCTS, e.g. REPAIRING
    • B29C66/00General aspects of processes or apparatus for joining preformed parts
    • B29C66/90Measuring or controlling the joining process
    • B29C66/91Measuring or controlling the joining process by measuring or controlling the temperature, the heat or the thermal flux
    • B29C66/914Measuring or controlling the joining process by measuring or controlling the temperature, the heat or the thermal flux by controlling or regulating the temperature, the heat or the thermal flux
    • B29C66/9161Measuring or controlling the joining process by measuring or controlling the temperature, the heat or the thermal flux by controlling or regulating the temperature, the heat or the thermal flux by controlling or regulating the heat or the thermal flux, i.e. the heat flux
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B29WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
    • B29CSHAPING OR JOINING OF PLASTICS; SHAPING OF MATERIAL IN A PLASTIC STATE, NOT OTHERWISE PROVIDED FOR; AFTER-TREATMENT OF THE SHAPED PRODUCTS, e.g. REPAIRING
    • B29C66/00General aspects of processes or apparatus for joining preformed parts
    • B29C66/90Measuring or controlling the joining process
    • B29C66/91Measuring or controlling the joining process by measuring or controlling the temperature, the heat or the thermal flux
    • B29C66/919Measuring or controlling the joining process by measuring or controlling the temperature, the heat or the thermal flux characterised by specific temperature, heat or thermal flux values or ranges
    • B29C66/9192Measuring or controlling the joining process by measuring or controlling the temperature, the heat or the thermal flux characterised by specific temperature, heat or thermal flux values or ranges in explicit relation to another variable, e.g. temperature diagrams
    • B29C66/91921Measuring or controlling the joining process by measuring or controlling the temperature, the heat or the thermal flux characterised by specific temperature, heat or thermal flux values or ranges in explicit relation to another variable, e.g. temperature diagrams in explicit relation to another temperature, e.g. to the softening temperature or softening point, to the thermal degradation temperature or to the ambient temperature
    • B29C66/91931Measuring or controlling the joining process by measuring or controlling the temperature, the heat or the thermal flux characterised by specific temperature, heat or thermal flux values or ranges in explicit relation to another variable, e.g. temperature diagrams in explicit relation to another temperature, e.g. to the softening temperature or softening point, to the thermal degradation temperature or to the ambient temperature in explicit relation to the fusion temperature or melting point of the material of one of the parts to be joined
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M39/00Tubes, tube connectors, tube couplings, valves, access sites or the like, specially adapted for medical use
    • A61M39/10Tube connectors; Tube couplings
    • A61M2039/1027Quick-acting type connectors
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B29WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
    • B29CSHAPING OR JOINING OF PLASTICS; SHAPING OF MATERIAL IN A PLASTIC STATE, NOT OTHERWISE PROVIDED FOR; AFTER-TREATMENT OF THE SHAPED PRODUCTS, e.g. REPAIRING
    • B29C65/00Joining or sealing of preformed parts, e.g. welding of plastics materials; Apparatus therefor
    • B29C65/02Joining or sealing of preformed parts, e.g. welding of plastics materials; Apparatus therefor by heating, with or without pressure
    • B29C65/14Joining or sealing of preformed parts, e.g. welding of plastics materials; Apparatus therefor by heating, with or without pressure using wave energy, i.e. electromagnetic radiation, or particle radiation
    • B29C65/1403Joining or sealing of preformed parts, e.g. welding of plastics materials; Apparatus therefor by heating, with or without pressure using wave energy, i.e. electromagnetic radiation, or particle radiation characterised by the type of electromagnetic or particle radiation
    • B29C65/1412Infrared [IR] radiation
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B29WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
    • B29CSHAPING OR JOINING OF PLASTICS; SHAPING OF MATERIAL IN A PLASTIC STATE, NOT OTHERWISE PROVIDED FOR; AFTER-TREATMENT OF THE SHAPED PRODUCTS, e.g. REPAIRING
    • B29C66/00General aspects of processes or apparatus for joining preformed parts
    • B29C66/50General aspects of joining tubular articles; General aspects of joining long products, i.e. bars or profiled elements; General aspects of joining single elements to tubular articles, hollow articles or bars; General aspects of joining several hollow-preforms to form hollow or tubular articles
    • B29C66/51Joining tubular articles, profiled elements or bars; Joining single elements to tubular articles, hollow articles or bars; Joining several hollow-preforms to form hollow or tubular articles
    • B29C66/53Joining single elements to tubular articles, hollow articles or bars
    • B29C66/534Joining single elements to open ends of tubular or hollow articles or to the ends of bars
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B29WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
    • B29KINDEXING SCHEME ASSOCIATED WITH SUBCLASSES B29B, B29C OR B29D, RELATING TO MOULDING MATERIALS OR TO MATERIALS FOR MOULDS, REINFORCEMENTS, FILLERS OR PREFORMED PARTS, e.g. INSERTS
    • B29K2995/00Properties of moulding materials, reinforcements, fillers, preformed parts or moulds
    • B29K2995/0018Properties of moulding materials, reinforcements, fillers, preformed parts or moulds having particular optical properties, e.g. fluorescent or phosphorescent
    • B29K2995/0026Transparent
    • B29K2995/0027Transparent for light outside the visible spectrum

Definitions

  • U.S. Patent No. 4,157,723 discloses a sterile connector system in which two connector members are locked together, preferably with opaque, thermoplastic wall portions being carried on a conduit about their periphery by transparent wall portions of the conduit. The opaque wall portions are brought together into facing contact, and then exposed to sufficient radiant energy to cause the opaque wall portions to fuse together to open an aperture through the fused wall portions, to provide sealed communication between the interiors of the conduits.
  • This may be a sterile connection, particularly when the opaque, thermoplastic wall portion has a high melting range of over essentially 200°C.
  • Ammann et al. U.S. Application Serial No. 005,749, filed January 23, 1979, and Boggs et al. Application Serial No. 27,575, filed April 6, 1979 dis close further improvements on the sterile connector system of the type disclosed in the patent cited above.
  • Bellamy et al. Application Serial No. 091,688, filed November 5, 1979 discloses sterile connector systems connected to vials or flexible bags, with the type of sterile connector being similar to the previouslycited patent applications.
  • the sterile connector preferably has auxiliary sealing means, which may be opened from the exterior in a manual way without breach of sterility.
  • the type of sterile connector systems described in the patent and applications cited above makes practical the long-felt need of providing a highly reliable sterile transfer of materials between various containers, so that, as stated above, partial units of blood may be used and the remainder sent back to storage, and other sterile solutions which are particularly subject to growth of bacteria upon contamination may be entered without the requirement for immediate use of the entire unit of sterile material.
  • a sterile connector system which comprises a first connector member defining a first, hollow housing having an opaque, thermoplastic wall, and a first port for flow communication to and from the first hollow housing.
  • a second connector member defines a second hollow housing having a transparent, thermoplastic wall, the transparent wall being capable of being p ⁇ si-cione ⁇ adjacent to and along the opaque wall, and a second port for flow communication to and from the second hollow housing.
  • Means are provided in the hollow housings permittin the application of radiant energy to the adjacently-positioned opaque wall and transparent wall, to melt at least a portion of the opaque wall by absorption of radiant energy applied, and also to melt at least a portion of the transparent wall- primarily by heat conduction from the opaque wall, to cause a hole to open between the two walls and fusion of the materials of the walls together.
  • each of the first and second connector members may be single, molded pieces of thermoplastic, for great simplification of manufacture and reduction of cost, with the first hollow housing being made of an opaque, thermoplastic material and the second hollow hous ing being of a transparent, thermoplastic material.
  • the radiant energy is directed through the second transparent hollow housing to impinge and be absorbed by the first hollow housing, so that heat is generated in the opaque wall of the first hollow housing by absorption of the radiation, which heat is then transferred by conduction to the transparent wall through which the radiation passes, to cause both of them to fuse together and to open a hole between them in a manner similar to the technique described in the previouslycited patent.
  • Each of the first and second ports of the hollow housings are oreferabiv in sealed flow communication with first and second containers, for the sterile retention and also sterile transfer of materials.
  • first hollow housing is tubular in shape and to have an opa ⁇ ue, thermoplastic end wall.
  • the second hollow housing is also preferably tubular, and is transparent, as stated above, having an open end and defining an interior, trans parent thermoplastic wall across the bore thereof.
  • the second port for flow communication to and from the second hollow housing may be at a position separated from the open end of the second, hollow, transparent tubular housing by the interior, transparent wall.
  • the first housing is telescopically inserted through the open end into the bore of the second housing, with the opaque end wall and the interior, trans parent wall of the respective housings being positioned together in adjacent, facing relation to each other within the second housing.
  • the radiant energy may be applied to pass through the wall of the transparent second housing, to impinge on the opaque end wall in sufficient intensity to heat it to the melting point.
  • the heat is transferred to the interior, transparent wall primarily by conduction so that the two walls fuse together and open an aperture for sterile connection.
  • the materials of the first and second connector members of this invention to be made of a substantially crystalline material such as poly (4-methyl-1-pentene) sold under the trademark TPX by Mitsui Chemical Company, or ether materials as described in the Boggs et al. application cited above.
  • the preferred substantially crystalline materials exhibit melting points above essentially 200°C.
  • the two walls fuse together so that a sealed aperture is formed between the two walls, with the surface being sterile because of the high temperatures encountered during the fusing and hole-opening step.
  • the opaque end wall and interior, transparent wall of the first and second connector members prefferably be inclined at an acute angle to the axes of the first and second housing, the angle being typically 30° to 60°. This permits the two wails which are to be melted to be more conveniently exposed to irradiation through the transparent, outer wall of the second connector member.
  • each housing may define one member of key and keyway means, to interact together to prevent relative rotation thereof.
  • first and second connector members when in tubular form, may be tapered to cooperatively define a luer-type seal therebetween for added sealing and mechanical support of the connector structure, above and beyond the sterile sealing which is provided by the fusion of the opaque end wall and interior, transparent wall.
  • Figure 1 is a partly schematic elevational view of the sterile connector system of this invention, connected to a pair of sealed collapsible containers, taken partly in section.
  • Figure 2 is a plan view of the first, opaque connector member of this invention.
  • Figure 3 is a longitudinal sectional view of the structure of Figure 2, but rotated 90° about its longitudinal axis.
  • Figmre 4 is a plan view of the second, transparent connector member of this invention.
  • Figure 5 is a longitudinal sectional view of the structure of Figure 4, but rotated 90° about its iongitudinal axis.
  • Figure 6 is a longitudinal sectional view of the connected first and second connector members of Figure 1.
  • Figure 1 shows a connector system of joined first connector member 10 and second connector member 12.
  • Each of the connector members is connected respectively to first and second ports 14, 16 which, in turn, are each connected to flexible plastic tubing 18, 20, in sealed manner, which is joined to containers for the sterile retention of various contents, for example collapsible plastic bags 22, 24.
  • Bags 22, 24 may be blood bags, as part of single or multiple blood bag systems for the collection and/or storage of blood and its various components such as plasma, packed red cells, platelets, or while cells.
  • bags 22, 24 may contain respective materials for mixing, for example lyopnilized medication in one bag and a carbohydrate solution in the other for total parenteral nutrition, or any other material for which sterile retention after mixing or transfer from one container to another is desired.
  • one or more of the containers 22, 24 may be a rigid or semi-rigid vial of a design and for purposes similar to that shown in the previously cited Bellamy et al. patent.
  • the connector system of this invention may be used for any prupose where it is desired to transfer the contents of one container to another for mixing or separation of components or the like, with reliable maintenance of sterility during and after the transfer.
  • the first connector member 10 is shewn in detail in Figures 2 and 3.
  • connector 10 may be a single, molded piece of TPX thermoplastic, sold by the Mitsui Chemical Company and filled for example with powdered charcoal, carbon black, or the like to render it opaque as described in the previously-cited Boggs et al. application.
  • First connector member 10 comprises a first hollow tubular housing 26 having an opaque, thermoplastic end wall 28 as an integral part thereof.
  • First port 16 is also provided for communication to and from hollow housing 26, being sealed to tubing 20 for aseptic communication with bag 24.
  • Flanges 32 and 33 are provided to facilitate the manual insertion of first connector member 10 into second connector member 12, and to also aid positioning of the membrane for sealing. Additionally, first connector 10 may carry a longitudinally disposed key member 34 to fit into a keyway defined in second connector 12, to assist in the retention of the two housings together until the respective opaque end wall and interior transparent wall are fused together, and also to prevent relative rotation of the connector members 10, 12.
  • the end of port 16 may define a pointed spike 36 for manual penetration of diaphragm 38 by the collapsing of bellows 40, to provide an auxiliary sealing device, for example as shown in the copending Dossin application Serial No. 196,966, filed October 14, 1980.
  • second connector member 12 is shown, also defining a hollow housing 42.
  • Second connector member 12 may also be an integrally molded single piece of thermoplastic material, for example made of the same TPX thermoplastic but free of opaque filler so that housing 42 is transparent.
  • Interior transparent thermoplastic wall 44 is defined across the bore of second connector member 12.
  • Second port 14 is defined, sealed to tubing 13 and separated from the open end 46 of second connecter 12 by interior transparent wall 44, so that the entire interior area of tubing 18 and port 56 may be retained in sterile manner as long as wall 44 remains intact.
  • Second connector 12 defines on its exterior a keyway 48, sealed from the exterior by an outer wall 50.
  • Keyway 48 is adapted to receive key member 34 in tight, gripping relation in area 52, to assist in the retention of the two members 10, 12 together and also to prevent rotation.
  • the outer portion of keyway 48 is flared outwardly for ease of assembly, to receive key member 34 as first connector 10 is manually thrust into second connector 12, and to direct key member 34 into the tight portion 52 of the keyway 48.
  • port 14 of housing 12 may optionally also carry a spike member 36 at its end, enclosed by a boot member 40, so that diaphragm 38 may be penetrated as desired by the manual manipulation of spike 36 and longitudinally collapsible boot member 40.
  • connector member 10 in use, as connector member 10, 12 are brought together by inserting connector member 10 into connector member 12, opaque end wall 28 and interior transparent wall 44 are brought into proximate, overlying relationship and preferably in essentially substantially abutting relationship.
  • connector member 10 may be slightly tapered in area 54 to match a corresponding taper in area 56 of connector member 12, so that the two connector members fit together in a luer-type sealing relationship for added sealing benefit, with the interaction of key 34 and keyway 48 providing a nonrotatable relationship.
  • the assembled connectors 10, 12 may then be exposed to a source of strong light 58, or other radiation such as infrared radiation, focused through a lens if desired, and directed through the outer wall of second housing 12 and interior wall 44, to impinge upon opaque end wall 28 and be absorbed thereby.
  • a source of strong light 58 or other radiation such as infrared radiation
  • the intensity of the radiation utilized should be sufficient to provide enought energy to heat opaque end wall 28 into its melting range which, as previously stated, is preferably in excess of 200°C. to obtain sterilizing action.
  • Membrane 44 is correspondingly heated, primarily by conduction of the heat from end wall 28, but also possibly by some direct absorption of radiation, although interior wall 44 is substantially transparent.
  • first connector 10 may also be transparent, with an opaque layer carried on end wall 28.
  • a layer of ink, plastic or paint may be painted, sprayed or printed onto end wall 23, to yield results equivalent to those described above.

Landscapes

  • Engineering & Computer Science (AREA)
  • Mechanical Engineering (AREA)
  • Physics & Mathematics (AREA)
  • Health & Medical Sciences (AREA)
  • Thermal Sciences (AREA)
  • Toxicology (AREA)
  • Electromagnetism (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Biomedical Technology (AREA)
  • Public Health (AREA)
  • Pulmonology (AREA)
  • Hematology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Anesthesiology (AREA)
  • Veterinary Medicine (AREA)
  • Optics & Photonics (AREA)
  • Plasma & Fusion (AREA)
  • High Energy & Nuclear Physics (AREA)
  • Medical Preparation Storing Or Oral Administration Devices (AREA)
  • Infusion, Injection, And Reservoir Apparatuses (AREA)
EP19820900696 1981-01-19 1982-01-11 ONE-PIECE CONNECTORS AND STERILE CONNECTING SYSTEM. Withdrawn EP0069768A4 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US22592981A 1981-01-19 1981-01-19
US225929 2002-08-22

Publications (2)

Publication Number Publication Date
EP0069768A1 EP0069768A1 (en) 1983-01-19
EP0069768A4 true EP0069768A4 (en) 1984-08-23

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ID=22846858

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Application Number Title Priority Date Filing Date
EP19820900696 Withdrawn EP0069768A4 (en) 1981-01-19 1982-01-11 ONE-PIECE CONNECTORS AND STERILE CONNECTING SYSTEM.

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EP (1) EP0069768A4 (es)
JP (1) JPS57502153A (es)
ES (1) ES274987Y (es)
WO (1) WO1982002528A1 (es)

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WO1984002321A1 (en) * 1982-12-16 1984-06-21 Baxter Travenol Lab A fluid transfer member and assembly which include a radiant energy absorbing wall having optimal melt characteristics
US4611643A (en) * 1983-11-21 1986-09-16 Baxter Travenol Laboratories, Inc. Interlocking fluid transfer device and resulting assembly
EP0425646B1 (en) * 1989-05-05 1994-09-21 Baxter International Inc. Method and apparatus for making sterile connections between fluid conduit tubes
US5628726A (en) * 1995-02-16 1997-05-13 Duxbury Scientific, Inc. Blood collection system
DE19828650C2 (de) 1998-06-26 2000-10-19 Fresenius Medical Care De Gmbh Konnektorelement mit integriertem Absperrelement
KR100777702B1 (ko) * 2001-06-04 2007-11-21 삼성전자주식회사 플랫 패널 표시 장치 및 이의 구동 방법
US7722733B2 (en) * 2004-03-29 2010-05-25 Baxter International Inc. Method for sterile connection of tubing
ATE485075T1 (de) 2006-07-07 2010-11-15 Caridianbct Inc Verfahren zum verbinden thermoplastischer schläuche
CN101668558B (zh) * 2007-04-24 2013-01-23 海克隆实验室有限公司 无菌连接器系统
US7938454B2 (en) 2007-04-24 2011-05-10 Hyclone Laboratories, Inc. Sterile connector systems
US8448992B2 (en) * 2011-02-16 2013-05-28 Fenwal, Inc. Sterile docking device, medical fluid flow system with sterile docking device and method of using same
EP2722070B1 (en) 2011-12-21 2017-07-26 Fenwal, Inc. Fluid flow circuit
US9308709B2 (en) 2013-06-06 2016-04-12 Fenwal, Inc. Bonding apparatus and method
US9440396B2 (en) 2014-06-19 2016-09-13 Fenwal, Inc. Sterile connection device for making multiple connections
US9839582B2 (en) 2014-12-02 2017-12-12 Fenwal, Inc. Sterile connection syringe assemblies

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Publication number Priority date Publication date Assignee Title
DE1300635B (de) * 1964-09-07 1969-08-07 Dr Med Karl Friedrich Sterile Leitungsverbindung fuer den Durchfluss von Transfusions- oder Infusionsfluessigkeiten
US3986508A (en) * 1973-08-22 1976-10-19 Abcor, Inc. Sterilizable, medical connector for blood processing
DE2549097A1 (de) * 1975-11-03 1977-05-05 Werner Karl Heinz Schlauch
GB2041132A (en) * 1979-01-23 1980-09-03 Baxter Travenol Lab Connector member for sealed conduits
US4253500A (en) * 1979-07-27 1981-03-03 Baxter Travenol Laboratories, Inc. Sterile connector adapted for multiple junctions
WO1981001241A1 (en) * 1979-11-05 1981-05-14 Baxter Travenol Lab System for the sterile mixing of materials
GB2068735A (en) * 1980-01-16 1981-08-19 Kubota Y Device for determining location of the tip of catheter and pathological condition in the thorax
US4325417A (en) * 1979-04-06 1982-04-20 Baxter Travenol Laboratories, Inc. Connector member for sealed conduits utilizing crystalline plastic barrier membrane

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US4022256A (en) * 1975-08-06 1977-05-10 California Institute Of Technology Aseptic fluid transfer system
US4019512A (en) * 1975-12-04 1977-04-26 Tenczar Francis J Adhesively activated sterile connector

Patent Citations (8)

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Publication number Priority date Publication date Assignee Title
DE1300635B (de) * 1964-09-07 1969-08-07 Dr Med Karl Friedrich Sterile Leitungsverbindung fuer den Durchfluss von Transfusions- oder Infusionsfluessigkeiten
US3986508A (en) * 1973-08-22 1976-10-19 Abcor, Inc. Sterilizable, medical connector for blood processing
DE2549097A1 (de) * 1975-11-03 1977-05-05 Werner Karl Heinz Schlauch
GB2041132A (en) * 1979-01-23 1980-09-03 Baxter Travenol Lab Connector member for sealed conduits
US4325417A (en) * 1979-04-06 1982-04-20 Baxter Travenol Laboratories, Inc. Connector member for sealed conduits utilizing crystalline plastic barrier membrane
US4253500A (en) * 1979-07-27 1981-03-03 Baxter Travenol Laboratories, Inc. Sterile connector adapted for multiple junctions
WO1981001241A1 (en) * 1979-11-05 1981-05-14 Baxter Travenol Lab System for the sterile mixing of materials
GB2068735A (en) * 1980-01-16 1981-08-19 Kubota Y Device for determining location of the tip of catheter and pathological condition in the thorax

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Title
See also references of WO8202528A1 *

Also Published As

Publication number Publication date
EP0069768A1 (en) 1983-01-19
ES274987Y (es) 1985-04-01
ES274987U (es) 1984-10-01
WO1982002528A1 (en) 1982-08-05
JPS57502153A (es) 1982-12-09

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Inventor name: BOGGS, DANIEL R.

Inventor name: GRANZOW, DANIEL B.

Inventor name: KRUGER, ROBERT J.