EP0060440A1 - Pièce de serrage rabattable munie d'un soufflet et prévue pour retenir un tube - Google Patents

Pièce de serrage rabattable munie d'un soufflet et prévue pour retenir un tube Download PDF

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Publication number
EP0060440A1
EP0060440A1 EP82101622A EP82101622A EP0060440A1 EP 0060440 A1 EP0060440 A1 EP 0060440A1 EP 82101622 A EP82101622 A EP 82101622A EP 82101622 A EP82101622 A EP 82101622A EP 0060440 A1 EP0060440 A1 EP 0060440A1
Authority
EP
European Patent Office
Prior art keywords
tube
shells
bellows
hinge
holding
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
EP82101622A
Other languages
German (de)
English (en)
Other versions
EP0060440B1 (fr
Inventor
Frank Landwehr
Heinz Wanner
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Boehringer Ingelheim Pharma GmbH and Co KG
Original Assignee
Dr Karl Thomae GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Dr Karl Thomae GmbH filed Critical Dr Karl Thomae GmbH
Priority to AT82101622T priority Critical patent/ATE7862T1/de
Publication of EP0060440A1 publication Critical patent/EP0060440A1/fr
Application granted granted Critical
Publication of EP0060440B1 publication Critical patent/EP0060440B1/fr
Expired legal-status Critical Current

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Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L9/00—Supporting devices; Holding devices
    • B01L9/54—Supports specially adapted for pipettes and burettes
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/02—Burettes; Pipettes
    • B01L3/021—Pipettes, i.e. with only one conduit for withdrawing and redistributing liquids

Definitions

  • the invention relates to a hinged clamping piece with a bellows attachment for receiving a primary packaging in the form of an elongated cylindrical tube.
  • micropipettes have been used to administer small amounts of pharmaceutical liquids.
  • the medicinal liquid it is necessary for the medicinal liquid to be present in larger storage containers which allow the micropipettes to be filled.
  • Medicinal liquids that contaminate very easily or that are very expensive to produce e.g. interferon solutions
  • this problem can be solved in that a Elongated tube, for example a capillary, which contains the medicinal liquid and is closed at both ends, in a hinged holding device, consisting of two half-shells, initially referred to as a hinged clamping piece, is inserted flush with the inner walls of this holding device.
  • a hinged holding device consisting of two half-shells, initially referred to as a hinged clamping piece
  • the tube is opened on its side facing the rear end of the clamping piece, immediately before application.
  • a bellows is pushed onto the shaft provided at the rear end of the clamping piece; the other, still closed end of the tube is then opened, the contents being removed from the tube by manual pressure on the bellows, for example in the form of individual drops or a thin jet.
  • the clamping piece is provided with a holding and supporting device by means of which it can be opened by means of two fingers to such an extent that the tube to be inserted can be brought into the intended position without problems.
  • a closing device for. B. a locking device, for example in the area of the above-mentioned holding and supporting device.
  • the clamping piece is constructed in such a way that the tube to be accommodated is centered when the two half-shells are folded open and pressed together in the holding and supporting device which surrounds the two half-shells at a suitable point.
  • the calibration of the inner diameter of the clamping piece formed from the two half-shells in the folded and locked state corresponds exactly to the outer contour of the tube. This ensures that the tube is fixed in the clamping piece so that the overpressure which arises from the compression of the bellows and leads to the squeezing out of the liquid from the tube opened at both ends cannot escape ineffectively on secondary paths.
  • the holding and support device which is firmly connected to the two half-shells, corresponds to the ergonomic requirements when inserting the tube, when applying the drops and during the application-specific break between two applications by avoiding any contact of the tube end with other objects.
  • a bellows is preferably used as the bellows required to squeeze the drops out of the tube.
  • the bellows attachment consists of a cylindrical shaft that merges into a bellows with one or more fins. After the corresponding end of the tube has been cut off, the bellows attachment is pushed onto the rear end of the clamping piece, after its half-shells have been folded and locked over the tube, on a specially provided and appropriately adapted shaft.
  • the bellows is provided with a sufficiently large opening at the rear end that prevents premature overpressure or underpressure when the bellows attachment is pushed onto the shaft.
  • the two half-shells of the clamping piece are connected to one another by a hinge.
  • a hinge z. B a thinned zone of the same material from which the half-shells are made (for plastics this is the best solution from a spraying point of view), or a film holding the two half-shells together.
  • This hinge can extend over the entire length of the half-shells, but it can also be attached only in the area of the holding and supporting device.
  • the two half-shells are spread apart so far that the tube can be inserted properly.
  • the problem-free handling is made possible by a recess on the hinge side in the support and holding device, which, in its dimensional design, also serves as an opening stop.
  • the two half-shells are closed by shifting the finger pressure on the holding and supporting device in the direction of the open edges of the half-shells and firmly connected to one another by means of a snap-in or snap-on device or another suitable device.
  • the end of the tube pointing towards the shaft for attaching the bellows is first removed; this happens e.g. B. by breaking the tube tip at a predetermined breaking point or by cutting it off with a knife or sawing it off with a saw.
  • the bellows attachment is then pushed over this open tube end and attached to the shaft provided for this purpose. Only then is the other end of the tube removed in an analogous manner.
  • the capillary forces prevent the liquid from leaking out even before the application is actually held when the application device is held vertically.
  • the holding or supporting device is held at recesses provided between the thumb and the middle finger.
  • the index finger tip is on the front of the bellows, for. B. a bellows, laid, whereby the bellows opening located there is automatically covered or closed.
  • FIG. 1a shows a main view of the clamping piece with the holding and supporting device
  • FIG. 1b shows a section through the holding and supporting device in the plane A - B of FIG. 1a.
  • FIG. 2 shows a partial section through a tube which is welded at both ends and which contains the medicinal liquid.
  • FIG. 3 again shows a main view of the clamping piece, but with an inserted tube; the two ends of the tube protruding from the clamp are visible.
  • FIG. 4 shows a bellows attachment, the lower part of which is cut.
  • FIG. 5 shows a section through the holding and supporting device in the closed and in the open state.
  • FIGS. 1 to 5 (1) the hinged clamping piece, consisting essentially of the two opposing and identically designed half-shells (9) and (10) with the interior (16) and the holding and supporting device (5), which consists of two halves of identical shape, which are connected to each other by a hinge (18).
  • the tube (2) is closed at its ends (6) and (13), e.g. B. sealed, and optionally provided with a predetermined breaking point.
  • (3) is a bellows attachment with an opening (8) at its head end, (4) denotes a snap device in the holding and supporting device (5), which is attached to a hinge (18) and is preferably designed as a snap-in device.
  • the hinged clamping piece has at its end opposite the cannula tip (14) a shaft (7) which is integrated in the two half-shells.
  • the holding and supporting device (5) has a recess (11) on the hinge side in the two halves which can be rotated about the hinge, the rotational movement being effected by the opening stop (12). is limited.
  • the holding and supporting device (5) has at its outer boundary a recess (15) for receiving the thumb and the middle finger.
  • a hinge (18) connects the two parts of the holding and supporting device (5), but it can also connect the two half-shells (9) and (10) over their entire length or in certain areas. (17) is the drug liquid in the tube (2).
  • the tubes can be made of glass, metal or plastic (e.g. Teflon), it is advisable to manufacture the hinged clamping piece with the holding and supporting device and the attachable bellows from plastic materials such as plexiglass, polyethylene, polypropylene or polystyrene.
  • plastic materials such as plexiglass, polyethylene, polypropylene or polystyrene.
EP82101622A 1981-03-13 1982-03-03 Pièce de serrage rabattable munie d'un soufflet et prévue pour retenir un tube Expired EP0060440B1 (fr)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AT82101622T ATE7862T1 (de) 1981-03-13 1982-03-03 Aufklappbares klemmstueck mit balgaufsatz zur aufnahme eines roehrchens.

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE8107209U 1981-03-13
DE19818107209U DE8107209U1 (de) 1981-03-13 1981-03-13 Aufklappbares klemmstueck mit balgaufsatz zur aufnahme eines primaerpackmittels in form eines langgestreckten zylindrischen roehrchens

Publications (2)

Publication Number Publication Date
EP0060440A1 true EP0060440A1 (fr) 1982-09-22
EP0060440B1 EP0060440B1 (fr) 1984-06-13

Family

ID=6725597

Family Applications (1)

Application Number Title Priority Date Filing Date
EP82101622A Expired EP0060440B1 (fr) 1981-03-13 1982-03-03 Pièce de serrage rabattable munie d'un soufflet et prévue pour retenir un tube

Country Status (5)

Country Link
US (1) US4413754A (fr)
EP (1) EP0060440B1 (fr)
JP (1) JPS57177753A (fr)
AT (1) ATE7862T1 (fr)
DE (2) DE8107209U1 (fr)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE8604613U1 (de) * 1986-02-21 1986-04-03 Dr. Karl Thomae Gmbh, 7950 Biberach Kolbenapplikator mit Klemmvorrichtung zur Aufnahme eines Primärpackmittels in Form eines langgestreckten zylindrischen Röhrchens
JPH0720134B2 (ja) * 1987-10-12 1995-03-06 日本電信電話株式会社 輻輳制御方法
US5344666A (en) * 1992-03-12 1994-09-06 Levine Marshall S Liquid dispenser
DE4420594C2 (de) * 1994-06-14 1997-04-24 Bernd Hansen Behältnis für fließfähige, insbesondere pasteuse Stoffe
US6843802B1 (en) * 2000-11-16 2005-01-18 Cordis Corporation Delivery apparatus for a self expanding retractable stent
US8173071B2 (en) * 2006-08-29 2012-05-08 International Business Machines Corporation Micro-fluidic test apparatus and method
US20210121645A1 (en) * 2019-10-28 2021-04-29 NS3 Biotech LLC Single-use dispenser with multiple delivery options

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2008289A1 (de) * 1969-02-27 1970-09-10 Gilford Instr Labor Inc Verfahren und Vorrichtung zum Füllen von Kapillarröhrchen mit Blut oder anderen Flüssigkeiten
GB1205564A (en) * 1966-09-21 1970-09-16 Hemolectors Ltd Fluid collecting apparatus
DE2217230A1 (de) * 1971-05-28 1972-12-07 Becton Dickinson Co Verfahren und Vorrichtung zum Messen kleiner Mengen einer gasförmigen oder flüssigen Probe
DE2438892A1 (de) * 1973-08-15 1975-02-20 Donald Albert Ham Verschliessbarer behaelter
AT357983B (de) * 1976-10-22 1980-08-11 Donbavand Martin Dr Vorrichtung zur dichtenden verriegelung von in der laboratoriumstechnik verwendbaren, genormten, austauschbaren kegelschliff-ver- bindungen aus glas oder quarz

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3233785A (en) * 1962-09-13 1966-02-08 Dade Reagents Inc Rinsing pipette
US3568673A (en) * 1968-11-04 1971-03-09 Bard Inc C R Needle bevel guard for intravenous catheter
US3574306A (en) * 1969-01-13 1971-04-13 Deseret Pharma Needle protector
US3834241A (en) * 1973-04-30 1974-09-10 R Garren Pipette
DE2851532C2 (de) * 1978-11-29 1981-02-19 Boehringer Mannheim Gmbh, 6800 Mannheim Pipette mit elastischem Balg
US4291694A (en) * 1979-10-29 1981-09-29 Chai S Apparatus and method for performing a thoracic operation

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1205564A (en) * 1966-09-21 1970-09-16 Hemolectors Ltd Fluid collecting apparatus
DE2008289A1 (de) * 1969-02-27 1970-09-10 Gilford Instr Labor Inc Verfahren und Vorrichtung zum Füllen von Kapillarröhrchen mit Blut oder anderen Flüssigkeiten
DE2217230A1 (de) * 1971-05-28 1972-12-07 Becton Dickinson Co Verfahren und Vorrichtung zum Messen kleiner Mengen einer gasförmigen oder flüssigen Probe
DE2438892A1 (de) * 1973-08-15 1975-02-20 Donald Albert Ham Verschliessbarer behaelter
AT357983B (de) * 1976-10-22 1980-08-11 Donbavand Martin Dr Vorrichtung zur dichtenden verriegelung von in der laboratoriumstechnik verwendbaren, genormten, austauschbaren kegelschliff-ver- bindungen aus glas oder quarz

Also Published As

Publication number Publication date
US4413754A (en) 1983-11-08
ATE7862T1 (de) 1984-06-15
DE3260231D1 (en) 1984-07-19
JPS57177753A (en) 1982-11-01
DE8107209U1 (de) 1981-12-03
EP0060440B1 (fr) 1984-06-13

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