EP0005538A1 - Childproof blister package for medicaments - Google Patents

Childproof blister package for medicaments Download PDF

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Publication number
EP0005538A1
EP0005538A1 EP79101489A EP79101489A EP0005538A1 EP 0005538 A1 EP0005538 A1 EP 0005538A1 EP 79101489 A EP79101489 A EP 79101489A EP 79101489 A EP79101489 A EP 79101489A EP 0005538 A1 EP0005538 A1 EP 0005538A1
Authority
EP
European Patent Office
Prior art keywords
child
incisions
sealing edge
blister pack
medicaments
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
EP79101489A
Other languages
German (de)
French (fr)
Other versions
EP0005538B1 (en
Inventor
Wilfried De Felice
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Hoechst AG
Original Assignee
Hoechst AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoechst AG filed Critical Hoechst AG
Priority to AT79101489T priority Critical patent/ATE48T1/en
Publication of EP0005538A1 publication Critical patent/EP0005538A1/en
Application granted granted Critical
Publication of EP0005538B1 publication Critical patent/EP0005538B1/en
Expired legal-status Critical Current

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Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65D—CONTAINERS FOR STORAGE OR TRANSPORT OF ARTICLES OR MATERIALS, e.g. BAGS, BARRELS, BOTTLES, BOXES, CANS, CARTONS, CRATES, DRUMS, JARS, TANKS, HOPPERS, FORWARDING CONTAINERS; ACCESSORIES, CLOSURES, OR FITTINGS THEREFOR; PACKAGING ELEMENTS; PACKAGES
    • B65D75/00—Packages comprising articles or materials partially or wholly enclosed in strips, sheets, blanks, tubes or webs of flexible sheet material, e.g. in folded wrappers
    • B65D75/52—Details
    • B65D75/58—Opening or contents-removing devices added or incorporated during package manufacture
    • B65D75/5827—Tear-lines provided in a wall portion
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65D—CONTAINERS FOR STORAGE OR TRANSPORT OF ARTICLES OR MATERIALS, e.g. BAGS, BARRELS, BOTTLES, BOXES, CANS, CARTONS, CRATES, DRUMS, JARS, TANKS, HOPPERS, FORWARDING CONTAINERS; ACCESSORIES, CLOSURES, OR FITTINGS THEREFOR; PACKAGING ELEMENTS; PACKAGES
    • B65D75/00—Packages comprising articles or materials partially or wholly enclosed in strips, sheets, blanks, tubes or webs of flexible sheet material, e.g. in folded wrappers
    • B65D75/28—Articles or materials wholly enclosed in composite wrappers, i.e. wrappers formed by associating or interconnecting two or more sheets or blanks
    • B65D75/30—Articles or materials enclosed between two opposed sheets or blanks having their margins united, e.g. by pressure-sensitive adhesive, crimping, heat-sealing, or welding
    • B65D75/32—Articles or materials enclosed between two opposed sheets or blanks having their margins united, e.g. by pressure-sensitive adhesive, crimping, heat-sealing, or welding one or both sheets or blanks being recessed to accommodate contents
    • B65D75/325—Articles or materials enclosed between two opposed sheets or blanks having their margins united, e.g. by pressure-sensitive adhesive, crimping, heat-sealing, or welding one or both sheets or blanks being recessed to accommodate contents one sheet being recessed, and the other being a flat not- rigid sheet, e.g. puncturable or peelable foil
    • B65D75/327—Articles or materials enclosed between two opposed sheets or blanks having their margins united, e.g. by pressure-sensitive adhesive, crimping, heat-sealing, or welding one or both sheets or blanks being recessed to accommodate contents one sheet being recessed, and the other being a flat not- rigid sheet, e.g. puncturable or peelable foil and forming several compartments
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65D—CONTAINERS FOR STORAGE OR TRANSPORT OF ARTICLES OR MATERIALS, e.g. BAGS, BARRELS, BOTTLES, BOXES, CANS, CARTONS, CRATES, DRUMS, JARS, TANKS, HOPPERS, FORWARDING CONTAINERS; ACCESSORIES, CLOSURES, OR FITTINGS THEREFOR; PACKAGING ELEMENTS; PACKAGES
    • B65D2215/00—Child-proof means
    • B65D2215/04—Child-proof means requiring the combination of different actions in succession
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65D—CONTAINERS FOR STORAGE OR TRANSPORT OF ARTICLES OR MATERIALS, e.g. BAGS, BARRELS, BOTTLES, BOXES, CANS, CARTONS, CRATES, DRUMS, JARS, TANKS, HOPPERS, FORWARDING CONTAINERS; ACCESSORIES, CLOSURES, OR FITTINGS THEREFOR; PACKAGING ELEMENTS; PACKAGES
    • B65D2575/00—Packages comprising articles or materials partially or wholly enclosed in strips, sheets, blanks, tubes or webs of flexible sheet material, e.g. in folded wrappers
    • B65D2575/28—Articles or materials wholly enclosed in composite wrappers, i.e. wrappers formed by association or interconnecting two or more sheets or blanks
    • B65D2575/30—Articles or materials enclosed between two opposed sheets or blanks having their margins united, e.g. by pressure-sensitive adhesive, crimping, heat-sealing, or welding
    • B65D2575/32—Articles or materials enclosed between two opposed sheets or blanks having their margins united, e.g. by pressure-sensitive adhesive, crimping, heat-sealing, or welding one or both sheets or blanks being recessed to accommodate contents
    • B65D2575/3209—Details
    • B65D2575/3218—Details with special means for gaining access to the contents
    • B65D2575/3227—Cuts or weakening lines
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65D—CONTAINERS FOR STORAGE OR TRANSPORT OF ARTICLES OR MATERIALS, e.g. BAGS, BARRELS, BOTTLES, BOXES, CANS, CARTONS, CRATES, DRUMS, JARS, TANKS, HOPPERS, FORWARDING CONTAINERS; ACCESSORIES, CLOSURES, OR FITTINGS THEREFOR; PACKAGING ELEMENTS; PACKAGES
    • B65D2585/00—Containers, packaging elements or packages specially adapted for particular articles or materials
    • B65D2585/56—Containers, packaging elements or packages specially adapted for particular articles or materials for medicinal tablets or pills

Definitions

  • the invention relates to a child-resistant blister pack for medicines in various dosage forms, such as tablets, capsules, dragees, suppositories, etc., which consists of a thermoformed thermoformed film provided with cups and a non-push-through cover film sealed with it and stamped into the sealing edge of corner-forming incisions are.
  • Blister packs for medicaments which are intended to prevent children from accessing the medication are known per se, but have the disadvantage that they have not hitherto been able to be produced economically.
  • New packaging machines have to be purchased for the previously proposed blister packs, since they cannot be produced with the usual machines.
  • the object of the present invention was therefore to overcome these known disadvantages.
  • a rectangular blister pack will have four right-angled or other shaped, fold-out, sharp-edged cutting tips.
  • the child-resistant blister pack (1) shown in FIG. 1 can be produced on conventional deep-drawing systems are, whose technical production process is known to take place such that the heated plastic film ( 2 ) is deep-drawn into cups (4) by vacuum or compressed air. These bowls are then filled with the drug, e.g. tablets, capsules, dragees, suppositories, etc. (5) and welded to a non-push-through cover film (3) by means of heated rollers or plates under pressure against the deep-drawn plastic film (2). Then the incisions (6) are punched into the sealing edge and the blister packs provided with the incisions are punched out in one work cycle.
  • the drug e.g. tablets, capsules, dragees, suppositories, etc.
  • the patient folds out the flat part (7) formed by the incisions in the opposite direction to the bowl (see FIGS. 2 and 3) and pushes the sharp-edged cutting tip of the right-angled flat part (7) into the cover film of a conveniently accessible bowl ( Figure 3).
  • the drug can then be removed by simply pressing the bowl.
  • the blister pack according to the invention is particularly advantageous if right-angled incisions are provided which can be processed without problems on conventional high-performance systems in the unfolded state and, in their use, provide particularly reliable protection against the removal of medication by children.
  • the package according to the invention can also be used for other solid or liquid contents if the requirement for a child-resistant package exists.

Landscapes

  • Engineering & Computer Science (AREA)
  • Mechanical Engineering (AREA)
  • Chemical & Material Sciences (AREA)
  • Composite Materials (AREA)
  • Packages (AREA)
  • Medical Preparation Storing Or Oral Administration Devices (AREA)
  • Containers And Plastic Fillers For Packaging (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)

Abstract

Blister package for medicaments safe from children consisting of a deep drawn plastics film provided with a plurality of recesses and a covering film that cannot be pushed through and is sealed with the plastics film, wherein incisions forming corners are made in the sealing edge.

Description

Gegenstand der Erfindung ist eine kindergesicherte Blisterpackung für Arzneimittel in verschiedenen Darreichungsformen, wie Tabletten, Kapseln, Dragees, Suppositorien usw.,die aus einer mit Näpfen versehenen, tiefgezogenen Kunstoftolie und einer mit ihr versiegelten, nicht-durchdrückbaren Deckfolie besteht undin deren Siegelrand eckenbildende Einschnitte eingestanzt sind.The invention relates to a child-resistant blister pack for medicines in various dosage forms, such as tablets, capsules, dragees, suppositories, etc., which consists of a thermoformed thermoformed film provided with cups and a non-push-through cover film sealed with it and stamped into the sealing edge of corner-forming incisions are.

Blisterpackungen für Arzneimittel, die den Zugriff zum Medikament durch Kinder verhindern sollen, sind an sich bekannt, weisen jedoch den Nachteil auf, daß sie bisher noch nicht wirtschaftlich hergestellt werden'können. Für die bisher vorgeschlagenen Blisterpackungen müssen neue Abpackmaschinen angeschafft werden, da sie mit den üblichen Maschinen nicht hergestellt werden können.Blister packs for medicaments which are intended to prevent children from accessing the medication are known per se, but have the disadvantage that they have not hitherto been able to be produced economically. New packaging machines have to be purchased for the previously proposed blister packs, since they cannot be produced with the usual machines.

So ist aus der DE-OS 25 52 812 eine kindersichere Packung für Medikamente bekannt, die anstelle der äußeren vier runden Ecken der Durchdrückpackung jeweils sägezahnartigen ausgebildete Ecken aufweist. Mit den sägezahnartigen Ekken soll die Deckfolie angeritzt und anschließend durch Druckeinwirkung auf den Napf das Medikament entnommen werden. Zur Herstellung der sägezahnartig ausgebildeten Ekken sind entsprechende Stanzwerkzeuge erforderlich, die auf den üblichen Hochleistungs-Tiefziehanlagen einem er- heblichen Verschleiß ausgesetzt sind. Dadurch besteht die Gefahr, daß nur stumpfe Sägezähne gebildet werden, die insbesondere für ältere Patienten das öffnen derartiger Blisterpackungen erschweren. Außerdem können die Sägezähne zu erheblichen Störungen auf schnellaufenden Abpackautomaten führen, weil der Weitertransport, das Abstapeln und das anschließende Kartonieren der Durchdrückpackungen wesentlich beeinträchtigt wird. Schließlich köni nen die scharfkantigen Sägezähne auch beim Patienten zu Verletzungen führen.From DE-OS 25 52 812 a child-safe package for medication is known, which has sawtooth-like corners instead of the four outer corners of the blister pack. With the sawtooth-like Ekken the cover film should be scratched and then the medication should be removed by applying pressure to the bowl. Appropriate punching tools are required to produce the sawtooth-shaped Ekken, which are subject to considerable wear and tear on the usual high-performance deep-drawing systems. As a result, there is a risk that only blunt saw teeth are formed, which make it particularly difficult for older patients to open such blister packs. In addition, the saw teeth can lead to considerable malfunctions on high-speed packaging machines because the further transport, stacking and subsequent cartoning of the blister packs is significantly impaired. Finally Kings i nen the sharp saw teeth also cause the patient to injury.

Aufgabe der vorliegenden Erfindung war es deshalb, diese bekannten Nachteile zu überwinden.The object of the present invention was therefore to overcome these known disadvantages.

Es wurde deshalb eine kindergesicherte Blisterpackung für Arzneimittel gefunden, die aus einer mit Näpfen versehenen, tiefgezogenen Kunstoffolie und einer mit ihr versie-I gelten,nicht durchdrückbaren Deckfolie besteht und in dere Siegelrand eckenbildende Einschnitte eingestanzt sind. Vorzugsweise werden die in den Siegelrand eingestanzten Einschnitte aus rechtwinkligen Schnitten gebildet, jedoch können sie auch anderes gestaltete Formen von Schneidelinien haben. Der in den Siegelrand eingestanzte Einschnitt wird vor Gebrauch herausgeklappt und weist dann einige oder mehrere scharkantige Schneidspitzen auf.It was therefore found a child-resistant blister pack for medications that are from a provided with wells, thermoformed plastic film and a versie- with it I is not push-through cover sheet and punched in particular sealing edge corner forming incisions. The incisions stamped into the sealing edge are preferably formed from right-angled cuts, but they can also have other shaped forms of cutting lines. The punched in the sealing edge incision is folded out before use and then has a few or several sharp-edged Schnei d peaks.

Im allgemeinen wird man bei einer rechtwinkligen Blisterpackung vier rechtwinklige oder anders gestaltete, herausklappbare, scharfkantige Schneidespitzen anbringen. Es ist jedoch auch möglich, insbesondere bei anders gestalteten geometrischen Grundflächen solcher Blisterpakkungen, weniger oder mehr als vier eckenbildende Einschnit te in den Siegelrand einzustanzen.In general, a rectangular blister pack will have four right-angled or other shaped, fold-out, sharp-edged cutting tips. However, it is also possible, particularly in the case of differently designed geometric base areas of such blister packs, to punch fewer or more than four corner-forming incisions into the sealing edge.

Die in Figur 1.gezeigte kindergesicherte Blisterpackung (1) kann auf herkömmlichen Tiefziehanlagen hergestellt werden, deren technischer Produktionsablauf bekanntlich so erfolgt, daß über der Werkzeugform die erwärmte Kunststoffolie (2) zu Näpfen (4) durch Vakuum oder Druckluft tiefgezogen wird. Diese Näpfe werden anschließend mit dem Arzneimittel, z.B. Tabletten, Kapseln, Dragees, Suppositorien usw. (5) gefüllt und mit einer nicht-durchdrückbaren Deckfolie (3) mittels beheizter Walzen oder Platten unter Druck gegen die tiefgezogene Kunststoffolie (2) verschweißt. Danach erfolgt in einem Arbeitstakt die Einstanzung der Einschnitte (6) in den Siegelrand sowie das Ausstanzen der mit den Einschnitten versehenen Blisterpakkungen.The child-resistant blister pack (1) shown in FIG. 1 can be produced on conventional deep-drawing systems are, whose technical production process is known to take place such that the heated plastic film ( 2 ) is deep-drawn into cups (4) by vacuum or compressed air. These bowls are then filled with the drug, e.g. tablets, capsules, dragees, suppositories, etc. (5) and welded to a non-push-through cover film (3) by means of heated rollers or plates under pressure against the deep-drawn plastic film (2). Then the incisions (6) are punched into the sealing edge and the blister packs provided with the incisions are punched out in one work cycle.

Zur Entnahme des Medikaments klappt der Patient den durch die Einschnitte gebildeten Flächenteil (7) in entgegengesetzter Richtung zum Napf heraus (vgl. Figur 2 und 3) und stößt die scharfkantige Schneidespitze des rechtwinklig abstehenden Flächenteils (7) in die Deckfolie eines bequem erreichbaren Napfes (Figur 3). Anschließend läßt sich das Arzneimittel durch einfaches Drücken auf den Napf herausnehmen.To take the medication, the patient folds out the flat part (7) formed by the incisions in the opposite direction to the bowl (see FIGS. 2 and 3) and pushes the sharp-edged cutting tip of the right-angled flat part (7) into the cover film of a conveniently accessible bowl ( Figure 3). The drug can then be removed by simply pressing the bowl.

Besonders vorteilhaft ist die erfindungsgemäße Blisterpackung, wenn rechtwinklige Einschnitte vorgesehen sind, die im nicht-ausgeklappten Zustand auf herkömmlichen Hochleistungsanlagen störungsfrei verarbeitet werden können und in ihrer Anwendung einen besonders sicheren Schutz gegen die Entnahme von Medikamenten durch Kinder bilden. Selbstverständlich kann die erfindungsgemäße Packung auch für andere feste oder flüssige Füllgüter verwendet werden, wenn die Forderung nach einer kindergesicherten Packung besteht.The blister pack according to the invention is particularly advantageous if right-angled incisions are provided which can be processed without problems on conventional high-performance systems in the unfolded state and, in their use, provide particularly reliable protection against the removal of medication by children. Of course, the package according to the invention can also be used for other solid or liquid contents if the requirement for a child-resistant package exists.

Claims (4)

1. Kindergesicherte Blisterpackung für Arzneimittel, dadurch gekennzeichnet, daß sie aus einer mit Näpfen versehenen, tiefgezogenen Kunststoffolie und einer mit ihr versiegelten, nicht-durchdrückbaren Deckfolie besteht und in deren Siegelrand eckenbildende Einschnitte eingestanzt sind.1. Child-resistant blister pack for medicinal products, characterized in that it consists of a thermoformed plastic film provided with cups and a sealable, non-penetrable cover film sealed with it and in the sealing edge of which corner-forming incisions are stamped. 2. Kindergesicherte Blisterpackung nach Anspruch 1, dadurch gekennzeichnet, daß die in den Siegelrand eingestanzten Einschnitte aus rechtwinkligen Schnitten gebildet werden.2. Child-resistant blister pack according to claim 1, characterized in that the incisions stamped into the sealing edge are formed from right-angled cuts. 3. Kindergesicherte Blisterpackung nach Anspruch 1, dadurch gekennzeichnet, daß die in den Siegelrand eingestanzten Einschnitte herausgeklappt werden können und dann einige oder mehrere scharfkantige Schneidespitzen aufweisen.3. Child-resistant blister pack according to claim 1, characterized in that the incisions punched into the sealing edge can be folded out and then have some or more sharp-edged cutting tips. 4. Kindergesicherte Blisterpackung nach Anspruch 1, dadurch gekennzeichnet, daß die Packung eine oder mehrere rechtwinklige oder anders gestaltete herausklappbare, scharfkantige Schneidespitzen aufweist.4. Child-resistant blister pack according to claim 1, characterized in that the pack has one or more right-angled or differently designed fold-out, sharp-edged cutting tips.
EP79101489A 1978-05-20 1979-05-16 Childproof blister package for medicaments Expired EP0005538B1 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AT79101489T ATE48T1 (en) 1978-05-20 1979-05-16 CHILD-RESISTANT BLISTER PACK FOR MEDICINAL PRODUCTS.

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE2822100 1978-05-20
DE19782822100 DE2822100A1 (en) 1978-05-20 1978-05-20 CHILD-SAFE BLISTER FOR MEDICINAL PRODUCTS

Publications (2)

Publication Number Publication Date
EP0005538A1 true EP0005538A1 (en) 1979-11-28
EP0005538B1 EP0005538B1 (en) 1981-04-29

Family

ID=6039845

Family Applications (1)

Application Number Title Priority Date Filing Date
EP79101489A Expired EP0005538B1 (en) 1978-05-20 1979-05-16 Childproof blister package for medicaments

Country Status (12)

Country Link
US (1) US4231477A (en)
EP (1) EP0005538B1 (en)
JP (1) JPS54152598A (en)
AT (1) ATE48T1 (en)
AU (1) AU521544B2 (en)
CA (1) CA1122934A (en)
DE (2) DE2822100A1 (en)
DK (1) DK206179A (en)
ES (1) ES250044Y (en)
GR (1) GR70662B (en)
PT (1) PT69637A (en)
ZA (1) ZA792428B (en)

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FR2723569A1 (en) * 1994-08-11 1996-02-16 Roussel Uclaf Packaging for medication in pill or capsule form

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US7475783B2 (en) * 2003-04-30 2009-01-13 Bang & Olufsen Medicom, A/S Dispenser for holding a means for holding a plurality of units for dispensing, and a method for operating the dispenser
EP1631509A4 (en) * 2003-05-20 2008-04-09 Smithkline Beecham Corp Child resistant blister packages utilizing walled structures enclosing medicament therein
US7752758B2 (en) * 2003-06-09 2010-07-13 Meadwestvaco Corporation System for storing and unpacking encased articles
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US7891100B2 (en) 2006-01-03 2011-02-22 Meadwestvaco Corporation System for opening an article encasement
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US20100084308A1 (en) * 2007-03-13 2010-04-08 Meadwestvaco Corporation Packaging system with a selectable locking feature
US20090087468A1 (en) * 2007-03-28 2009-04-02 Serena Stephenson Semi-Rigid Gel Article For Disinfecting A Surface
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US9108784B2 (en) 2012-06-29 2015-08-18 R.J. Reynolds Tobacco Company Dispensing container, packaged product assembly, and related method
US9346594B2 (en) 2013-03-07 2016-05-24 R. J. Reynolds Tobacco Company Dispensing container and related method and apparatus
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USD1003716S1 (en) * 2020-05-15 2023-11-07 Mead Johnson Nutrition Company Bottle lid with blister package
US12049345B2 (en) 2020-12-04 2024-07-30 Superior Bindery Inc. Child-safe cannabis packaging
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US3809220A (en) * 1972-07-24 1974-05-07 Becton Dickinson Co Child safety package
DE2360922A1 (en) * 1972-12-07 1974-06-12 Sandoz Ag BLISTER PACK
DE2321604A1 (en) * 1973-04-28 1974-11-21 Aluminium Walzwerke Singen CHILD RESISTANT PACKAGING
DE2543069A1 (en) * 1975-09-26 1977-03-31 Paco Packaging Blister pack having laminated body - with strippable reinforcing cover layer protecting rupturable foil layer
DE2552812A1 (en) * 1975-11-25 1977-06-02 Chephasaar Chemisch Pharmazeut Childproof tablet packaging of dished film - has serrated corners forming opener for a second pack

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0132285A2 (en) * 1983-06-25 1985-01-30 The University of Glasgow, University Court Medical and chemical testing kit
EP0132285A3 (en) * 1983-06-25 1987-10-28 The University of Glasgow, University Court Medical and chemical testing kit
FR2723569A1 (en) * 1994-08-11 1996-02-16 Roussel Uclaf Packaging for medication in pill or capsule form

Also Published As

Publication number Publication date
GR70662B (en) 1982-12-06
JPS54152598A (en) 1979-11-30
AU4720579A (en) 1979-11-22
US4231477A (en) 1980-11-04
EP0005538B1 (en) 1981-04-29
DE2960302D1 (en) 1981-08-06
ZA792428B (en) 1980-05-28
CA1122934A (en) 1982-05-04
DE2822100A1 (en) 1979-11-22
ATE48T1 (en) 1981-05-15
AU521544B2 (en) 1982-04-08
ES250044Y (en) 1981-01-01
DK206179A (en) 1979-11-21
ES250044U (en) 1980-07-01
PT69637A (en) 1979-06-01

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