EE05830B1 - Mikrovooluti meetod ja seade - Google Patents

Mikrovooluti meetod ja seade

Info

Publication number
EE05830B1
EE05830B1 EEP201900007A EEP201900007A EE05830B1 EE 05830 B1 EE05830 B1 EE 05830B1 EE P201900007 A EEP201900007 A EE P201900007A EE P201900007 A EEP201900007 A EE P201900007A EE 05830 B1 EE05830 B1 EE 05830B1
Authority
EE
Estonia
Prior art keywords
measurement
particles
measuring chamber
microfluidic method
proposed
Prior art date
Application number
EEP201900007A
Other languages
English (en)
Inventor
Jaan Ojarand
Mart Min
Olev MÄRTENS
Original Assignee
Tallinna Tehnikaülikool
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Tallinna Tehnikaülikool filed Critical Tallinna Tehnikaülikool
Priority to EEP201900007A priority Critical patent/EE05830B1/et
Priority to US16/783,647 priority patent/US11585772B2/en
Publication of EE201900007A publication Critical patent/EE201900007A/et
Publication of EE05830B1 publication Critical patent/EE05830B1/et

Links

Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
    • B01L3/502715—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by interfacing components, e.g. fluidic, electrical, optical or mechanical interfaces
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
    • B01L3/502753—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by bulk separation arrangements on lab-on-a-chip devices, e.g. for filtration or centrifugation
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/10—Investigating individual particles
    • G01N15/1023—Microstructural devices for non-optical measurement
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/10—Investigating individual particles
    • G01N15/1031—Investigating individual particles by measuring electrical or magnetic effects
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N27/00—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
    • G01N27/02—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating impedance
    • G01N27/04—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating impedance by investigating resistance
    • G01N27/12—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating impedance by investigating resistance of a solid body in dependence upon absorption of a fluid; of a solid body in dependence upon reaction with a fluid, for detecting components in the fluid
    • G01N27/128—Microapparatus
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
    • B01L2200/10—Integrating sample preparation and analysis in single entity, e.g. lab-on-a-chip concept
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/06—Auxiliary integrated devices, integrated components
    • B01L2300/0627—Sensor or part of a sensor is integrated
    • B01L2300/0645—Electrodes
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/10—Investigating individual particles
    • G01N2015/1006—Investigating individual particles for cytology
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N27/00—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
    • G01N27/02—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating impedance
    • G01N27/026—Dielectric impedance spectroscopy
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N27/00—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
    • G01N27/02—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating impedance
    • G01N27/04—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating impedance by investigating resistance
    • G01N27/06—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating impedance by investigating resistance of a liquid
    • G01N27/07—Construction of measuring vessels; Electrodes therefor

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Analytical Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Dispersion Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Clinical Laboratory Science (AREA)
  • Hematology (AREA)
  • Electrochemistry (AREA)
  • Molecular Biology (AREA)
  • Investigating Or Analyzing Materials By The Use Of Electric Means (AREA)

Abstract

Leiutise sisuks on mikrovooluti meetod ja seade vedelike, lahuste, gaaside ja osakeste omaduste tuvastamiseks, kus uuritav vedelik või gaas, koos osakestega või ilma, kulgeb vähemalt ühes kanalis, läbi omavahel elektriliselt isoleeritud, vähemalt ühe elektroodide paari vahel moodustuva miniatuurse mõõtekambri, kus mõõdetakse elektrilist impedantsi. Lahendust iseloomustab see, et tundlikkuse ja mõõtetäpsuse tõstmiseks samade mõõtmetega ruumiliste elektroodide paaride ristlõige väheneb mõlemalt poolt sujuvalt suunaga mõõtekambri poole. Tüüpiliselt on otstarbekas mitme kanaliga seadme kasutamine võrdlevaks mõõtmiseks ning diferentsiaalsete mõõteskeemide kasutamine kahe või enama kanaliga lahendustes.
EEP201900007A 2019-02-08 2019-02-08 Mikrovooluti meetod ja seade EE05830B1 (et)

Priority Applications (2)

Application Number Priority Date Filing Date Title
EEP201900007A EE05830B1 (et) 2019-02-08 2019-02-08 Mikrovooluti meetod ja seade
US16/783,647 US11585772B2 (en) 2019-02-08 2020-02-06 Microfluidic method and device

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EEP201900007A EE05830B1 (et) 2019-02-08 2019-02-08 Mikrovooluti meetod ja seade

Publications (2)

Publication Number Publication Date
EE201900007A EE201900007A (et) 2020-09-15
EE05830B1 true EE05830B1 (et) 2020-12-15

Family

ID=71945015

Family Applications (1)

Application Number Title Priority Date Filing Date
EEP201900007A EE05830B1 (et) 2019-02-08 2019-02-08 Mikrovooluti meetod ja seade

Country Status (2)

Country Link
US (1) US11585772B2 (et)
EE (1) EE05830B1 (et)

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2006104839A2 (en) * 2005-03-28 2006-10-05 Mds Analytical Technologies, A Business Unit Of Mds Inc. Multiwell sample plate with integrated impedance electrodes and connection scheme
EP2103933A1 (en) * 2008-02-25 2009-09-23 KeyNeurotek Pharmaceuticals AG Device and method for measuring impedance in organotypic tissues
WO2018108880A1 (en) * 2016-12-12 2018-06-21 Centre National De La Recherche Scientifique (Cnrs) Measuring system and manufacturing process of such a measuring system
WO2019028122A1 (en) * 2017-08-01 2019-02-07 Acea Biosciences, Inc. MONITORING IMPEDANCE OF CELLULAR SUBSTRATE OF CANCER CELLS OF DIFFERENT LINEAGE, ORIGIN OR STAGE

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6703819B2 (en) 2001-12-03 2004-03-09 Board Of Regents, The University Of Texas System Particle impedance sensor
US20070163883A1 (en) * 2004-02-04 2007-07-19 Evotec Technologies Gmbh Microfluidic system comprising an electrode arrangement and associated control method
US8329437B1 (en) 2004-07-29 2012-12-11 E.I. Spectra, Llc Disposable particle counter cartridge
US7417418B1 (en) 2005-06-14 2008-08-26 Ayliffe Harold E Thin film sensor
WO2007088517A2 (en) * 2006-02-01 2007-08-09 Ecole Polytechnique Federale De Lausanne (Epfl) Apparatus for manipulating, modifying and characterizing particles in a micro channel
DE102008018170B4 (de) * 2008-04-03 2010-05-12 NMI Naturwissenschaftliches und Medizinisches Institut an der Universität Tübingen Mikrofluidisches System und Verfahren zum Aufbau und zur anschließenden Kultivierung sowie nachfolgender Untersuchung von komplexen Zellanordnungen
NO329758B1 (no) * 2008-12-19 2010-12-13 Abbon As Flerfase stromningsmaler
EP2211164A1 (en) 2009-01-27 2010-07-28 Koninklijke Philips Electronics N.V. Fingered electrodes for microfluidic single particle analysis
US10274492B2 (en) * 2015-04-10 2019-04-30 The Curators Of The University Of Missouri High sensitivity impedance sensor
NZ740697A (en) * 2015-09-30 2022-07-01 Semen Refinement B V Microfluidic device for selection of semen
US10670544B2 (en) * 2018-08-13 2020-06-02 Saudi Arabian Oil Company Impedance-based flowline water cut measurement system

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2006104839A2 (en) * 2005-03-28 2006-10-05 Mds Analytical Technologies, A Business Unit Of Mds Inc. Multiwell sample plate with integrated impedance electrodes and connection scheme
EP2103933A1 (en) * 2008-02-25 2009-09-23 KeyNeurotek Pharmaceuticals AG Device and method for measuring impedance in organotypic tissues
WO2018108880A1 (en) * 2016-12-12 2018-06-21 Centre National De La Recherche Scientifique (Cnrs) Measuring system and manufacturing process of such a measuring system
WO2019028122A1 (en) * 2017-08-01 2019-02-07 Acea Biosciences, Inc. MONITORING IMPEDANCE OF CELLULAR SUBSTRATE OF CANCER CELLS OF DIFFERENT LINEAGE, ORIGIN OR STAGE

Also Published As

Publication number Publication date
US20200256816A1 (en) 2020-08-13
US11585772B2 (en) 2023-02-21
EE201900007A (et) 2020-09-15

Similar Documents

Publication Publication Date Title
CN105628752A (zh) 一种电化学传感器的标定方法
Bera et al. A flow measurement technique using a noncontact capacitance-type orifice transducer for a conducting liquid
US10823695B2 (en) Flow-type ion selective electrode, electrolyte concentration measuring device using the same, and biochemical automatic analyzer
CN106885762A (zh) 基于电容检测的闭环液滴微流控系统
EE05830B1 (et) Mikrovooluti meetod ja seade
US9335191B1 (en) High-precision pressure sampling head of pitot tube flow sensor
WO2020163099A3 (en) Measurement techniques for semiconductor nanowire-based sensors and related methods
US8528383B2 (en) Pressure sensor using gas/liquid interface
CN205002806U (zh) 双法兰取压平衡式流量计
JP2019506608A5 (et)
JPWO2021079833A1 (ja) 気体流量推定方法、孔径推定方法、気体流量推定装置及び孔径推定装置
US2310435A (en) Method of and apparatus for gas analysis
JPH04155220A (ja) 液体流量計
CN206725489U (zh) 双恒流源热导检测系统
CN202734878U (zh) 水滴型均速管流量测量装置及其使用的均速管流量测量探头
EP3693710A3 (en) Full bore magnetic flowmeter assembly with temperature sensing element
CN211085383U (zh) 一种可在线插拔的节流式流量计
CN210625939U (zh) 一种气压表的校验装置
CN203287055U (zh) 天然气计量用孔板
EA201650104A1 (ru) Датчик водорода в газовых средах
CN204594874U (zh) 高压微量气体浓度在线检测装置
JPS56111423A (en) Measuring device for gas flow rate of nozzle valve or the like
CN204028031U (zh) 一种可调节电极常数的电导率电极
CN105486730A (zh) 农用酸碱度检测装置
CN212007632U (zh) 一种通路压力传感装置