EE04705B1 - Kemokiinretseptori antagonisti kasutamine kombinatsioonis tsüklosporiiniga farmatseutilise kompositsiooni valmistamiseks, mis on ette nähtud siirdatud organite, kudede või rakkude hülgamisreaktsiooniraviks või vältimiseks - Google Patents

Kemokiinretseptori antagonisti kasutamine kombinatsioonis tsüklosporiiniga farmatseutilise kompositsiooni valmistamiseks, mis on ette nähtud siirdatud organite, kudede või rakkude hülgamisreaktsiooniraviks või vältimiseks

Info

Publication number
EE04705B1
EE04705B1 EEP200100159A EEP200100159A EE04705B1 EE 04705 B1 EE04705 B1 EE 04705B1 EE P200100159 A EEP200100159 A EE P200100159A EE P200100159 A EEP200100159 A EE P200100159A EE 04705 B1 EE04705 B1 EE 04705B1
Authority
EE
Estonia
Prior art keywords
ciclosporin
rejection
tissues
prevention
cells
Prior art date
Application number
EEP200100159A
Other languages
English (en)
Estonian (et)
Inventor
Grone Hermann-Joseph
J. Nelson Peter
Proudfoot Amanda
N. C. Wells Timothy
Original Assignee
Applied Research Systems Ars Holding N.V.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Applied Research Systems Ars Holding N.V. filed Critical Applied Research Systems Ars Holding N.V.
Publication of EE200100159A publication Critical patent/EE200100159A/xx
Publication of EE04705B1 publication Critical patent/EE04705B1/xx

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/19—Cytokines; Lymphokines; Interferons
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52—Cytokines; Lymphokines; Interferons
    • C07K14/521—Chemokines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Immunology (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Toxicology (AREA)
  • Molecular Biology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Biochemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Transplantation (AREA)
  • Epidemiology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
EEP200100159A 1998-09-18 1999-09-16 Kemokiinretseptori antagonisti kasutamine kombinatsioonis tsüklosporiiniga farmatseutilise kompositsiooni valmistamiseks, mis on ette nähtud siirdatud organite, kudede või rakkude hülgamisreaktsiooniraviks või vältimiseks EE04705B1 (et)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP98117697A EP1000626A1 (en) 1998-09-18 1998-09-18 Chemokine receptor antagonist and cyclosporin in combined therapy
PCT/EP1999/006844 WO2000016796A1 (en) 1998-09-18 1999-09-16 Chemokine receptor antagonist and cyclosporin in combined therapy

Publications (2)

Publication Number Publication Date
EE200100159A EE200100159A (et) 2002-08-15
EE04705B1 true EE04705B1 (et) 2006-10-16

Family

ID=8232654

Family Applications (1)

Application Number Title Priority Date Filing Date
EEP200100159A EE04705B1 (et) 1998-09-18 1999-09-16 Kemokiinretseptori antagonisti kasutamine kombinatsioonis tsüklosporiiniga farmatseutilise kompositsiooni valmistamiseks, mis on ette nähtud siirdatud organite, kudede või rakkude hülgamisreaktsiooniraviks või vältimiseks

Country Status (23)

Country Link
US (1) US6902728B1 (no)
EP (2) EP1000626A1 (no)
JP (1) JP2003519082A (no)
KR (1) KR100613950B1 (no)
CN (1) CN1177613C (no)
AR (1) AR021810A1 (no)
AT (1) ATE227582T1 (no)
AU (1) AU766595B2 (no)
BR (1) BR9913846A (no)
CA (1) CA2344370A1 (no)
DE (1) DE69903964T2 (no)
DK (1) DK1113811T3 (no)
EA (1) EA003181B1 (no)
EE (1) EE04705B1 (no)
ES (1) ES2186411T3 (no)
HK (1) HK1041225B (no)
IL (2) IL141899A0 (no)
NO (1) NO20011371D0 (no)
PT (1) PT1113811E (no)
SI (1) SI1113811T1 (no)
UA (1) UA60379C2 (no)
WO (1) WO2000016796A1 (no)
ZA (1) ZA200101909B (no)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7259136B2 (en) 1999-04-30 2007-08-21 Amylin Pharmaceuticals, Inc. Compositions and methods for treating peripheral vascular disease
US6740636B2 (en) * 2000-07-31 2004-05-25 Schering Aktiengesellschaft Non-peptide CCR1 receptor antagonists in combination with cyclosporin A for the treatment of heart transplant rejection
LT5132B (lt) 2000-07-31 2004-05-25 Schering Aktiengesellschaft Nepeptidiniai ccr1 receptorių antagonistai derinyje su ciklosporinu a širdies transplanto atmetimui gydyti
MX2010001307A (es) 2007-08-02 2010-07-30 Novimmune Sa Anticuerpos anti-proteína regulada con la activación, expresada y secretada por los linfocitos t normales y metodos de uso de los mismos.
DE112016003948T5 (de) 2015-08-31 2018-05-09 City Of Sapporo Molekulare verfahren zum beurteilen einer urothelialen erkrankung
JP6733968B2 (ja) * 2015-08-31 2020-08-05 日立化成株式会社 腎移植後合併症を評価するための分子法

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MX9703889A (es) * 1994-12-08 1997-08-30 Glaxo Group Ltd Peptido rantes y fragmentos y composiciones que lo contienen, para el tratamiento de la inflamacion.
AU712606B2 (en) * 1995-08-09 1999-11-11 Schering Corporation Combined use of interleukin-10 and cyclosporin for immunosuppression therapy
AU4054197A (en) * 1996-08-14 1998-03-06 Warner-Lambert Company 2-phenyl benzimidazole derivatives as mcp-1 antagonists
WO1998006751A1 (en) * 1996-08-16 1998-02-19 Research Corporation Technologies, Inc. Mcp-3, rantes and mip-1alpha receptor antagonists

Also Published As

Publication number Publication date
DK1113811T3 (da) 2003-03-10
HK1041225A1 (en) 2002-07-05
NO20011371L (no) 2001-03-16
KR20010075060A (ko) 2001-08-09
ATE227582T1 (de) 2002-11-15
EE200100159A (et) 2002-08-15
DE69903964D1 (en) 2002-12-19
PT1113811E (pt) 2003-03-31
ES2186411T3 (es) 2003-05-01
WO2000016796A1 (en) 2000-03-30
JP2003519082A (ja) 2003-06-17
BR9913846A (pt) 2001-06-05
HK1041225B (zh) 2005-04-22
CA2344370A1 (en) 2000-03-30
DE69903964T2 (de) 2003-03-27
SI1113811T1 (en) 2003-04-30
ZA200101909B (en) 2001-09-11
CN1177613C (zh) 2004-12-01
EA003181B1 (ru) 2003-02-27
AU766595B2 (en) 2003-10-16
EP1113811A1 (en) 2001-07-11
US6902728B1 (en) 2005-06-07
AR021810A1 (es) 2002-08-07
EP1113811B1 (en) 2002-11-13
CN1319021A (zh) 2001-10-24
AU6191499A (en) 2000-04-10
EP1000626A1 (en) 2000-05-17
IL141899A (en) 2007-12-03
KR100613950B1 (ko) 2006-08-18
EA200100366A1 (ru) 2001-08-27
UA60379C2 (uk) 2003-10-15
IL141899A0 (en) 2002-03-10
NO20011371D0 (no) 2001-03-16

Similar Documents

Publication Publication Date Title
EE200100459A (et) Ravimaine kombinatsioonis prootonpumba inhibiitori või H2 retseptori antagonistiga ning neid sisaldav farmatseutiline kompositsioon kasutamiseks mao-soolkonna häirete ravis
EP1178786A4 (en) PHARMACOLOGICALLY ACTIVE PROTEIN STABILIZING AGENTS; METHODS OF MANUFACTURE AND METHODS OF USE
EE200100458A (et) Ravimaine kombinatsioonis prootonpumba inhibiitori või H2 retseptori antagonistiga ning neid sisaldav farmatseutiline kompositsioon kasutamiseks mao-soolkonna häirete ravis
IL130424A (en) Compositions comprising ziprasidone or its hydrochloride monohydrate, their preparation and use thereof in the preparation of medicaments for treating psychosis
HUP0302969A3 (en) Npyy5 antagonists, pharmaceutical compositions containing them and their use
MA24193A1 (fr) Procedes pour la preparation de conjugue peg-ifn alpha physiologiquement actif, et pour la preparation de compositions pharmaceutiques le contenant et leur utilisation
HUP0203638A3 (en) Betha2-adrenergic receptor agonists and pharmaceutical compositions containing them and their use
HUP0203312A3 (en) Pharmaceutically active sulfonamide derivatives, process for their preparation, and pharmaceutical compositions and their use
EP1072273A4 (en) VASKULARISIERUNGSINHIBITOREN
HUP0203597A3 (en) Pharmaceutical compositions containing zolmitriptan, process for their preparation and their use
EP1719526A3 (en) Pharmaceutical combinations comprising a P2T receptor antagonist and another anti-thrombotic agent
DE59903751D1 (de) 2',2'-difluornucleoside zur immunosuppressiven therapie und kombinationspräparate
YU13301A (sh) Muskarinski agonisti i antagonisti
HUP0302333A3 (en) The use of glatiramer acetate (copolymer 1) for the preparation of pharmaceutical compositions available in the treatment of central nervous system disorders
HUP0103431A3 (en) Pharmaceutical, oral compositions containing 5-ht4 agonists or antagonists as active agent
IT1287174B1 (it) Diaril-ciclometilenpirazoli farmacologicamente attivi,procedimento per prepararli e composizioni farmaceutiche che li contengono
EP1185555A4 (en) COMPOSITIONS ISOLATED FROM SKIN CELLS AND METHODS FOR THEIR USE
ITMI991715A0 (it) Uso di agonisti dei recettori gabab per la terapia di mantenimento del l'astinenza da nicotina in soggetti nicotino-dipendenti
EE200100159A (et) Kemokiinretseptori antagonisti kasutamine kombinatsioonis tsüklosporiiniga farmatseutilise kompositsiooni valmistamiseks, mis on ette nähtud siirdatud organite, kudede või rakkude hülgamisreaktsiooniraviks või vältimiseks
DE10084344T1 (de) Cyclosporin enthaltende pharmazeutische Zusammensetzung
EE04903B1 (et) Taksoidi derivaatide kasutamine ravimi valmistamiseks, mis on ette n„htud rakkude ebaloomuliku proliferatsiooni raviks imetajate ajus
EE04914B1 (et) Eletriptaanvesinikbromiidi monohüdraat, selle kasutamine ja protsess selle valmistamiseks ning eletriptaanvesinikbromiidi monohüdraati sisaldav farmatseutiline kompositsioon
HUP9802897A3 (en) Optically active pyridyl-4h-1,2,4-oxadiazine derivatives, the use thereof in the treatment of vascular diseases and pharmaceutical composition containing the compound as active ingredient
IL154358A0 (en) Treatment of hiv-1 infection and inflammatory disease using cyclophilin receptor antagonists
NO20014692D0 (no) 3-amidinobenzensulfonamidderivater, medisinske sammensetninger inneholdende slike samt intermediater vedfremstillingen derav

Legal Events

Date Code Title Description
HD1A Correction of address
KB4A Valid patent at the end of a year

Effective date: 20061231

GB1A Change in the ownership or in the address of the owner
KB4A Valid patent at the end of a year

Effective date: 20071231

KB4A Valid patent at the end of a year

Effective date: 20081231

MM4A Lapsed by not paying the annual fees

Effective date: 20090916