EE03732B1 - Kinoliini ühendid kui leukotrieeni antagonistid - Google Patents

Kinoliini ühendid kui leukotrieeni antagonistid

Info

Publication number
EE03732B1
EE03732B1 EEP199900406A EEP9900406A EE03732B1 EE 03732 B1 EE03732 B1 EE 03732B1 EE P199900406 A EEP199900406 A EE P199900406A EE P9900406 A EEP9900406 A EE P9900406A EE 03732 B1 EE03732 B1 EE 03732B1
Authority
EE
Estonia
Prior art keywords
leukotriene antagonists
quinoline compounds
compounds
useful
antagonists
Prior art date
Application number
EEP199900406A
Other languages
English (en)
Estonian (et)
Inventor
H. Arison Byron
K. Balani Suresh
A. Baillie Thomas
Dufresne Claude
Original Assignee
Merck & Co., Inc.
Merck Frosst Canada & Co. / Merck Frosst Canada &Cie.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=26311611&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=EE03732(B1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Priority claimed from GBGB9711030.8A external-priority patent/GB9711030D0/en
Application filed by Merck & Co., Inc., Merck Frosst Canada & Co. / Merck Frosst Canada &Cie. filed Critical Merck & Co., Inc.
Publication of EE9900406A publication Critical patent/EE9900406A/xx
Publication of EE03732B1 publication Critical patent/EE03732B1/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/18—Halogen atoms or nitro radicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Pulmonology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Immunology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Quinoline Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
EEP199900406A 1997-03-13 1998-03-10 Kinoliini ühendid kui leukotrieeni antagonistid EE03732B1 (et)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US4041397P 1997-03-13 1997-03-13
GBGB9711030.8A GB9711030D0 (en) 1997-05-29 1997-05-29 Quinoline leukrotriene antagonists
PCT/US1998/004609 WO1998039970A1 (en) 1997-03-13 1998-03-10 Quinoline leukotriene antagonists

Publications (2)

Publication Number Publication Date
EE9900406A EE9900406A (et) 2000-04-17
EE03732B1 true EE03732B1 (et) 2002-06-17

Family

ID=26311611

Family Applications (1)

Application Number Title Priority Date Filing Date
EEP199900406A EE03732B1 (et) 1997-03-13 1998-03-10 Kinoliini ühendid kui leukotrieeni antagonistid

Country Status (14)

Country Link
EP (1) EP0971587B1 (ja)
JP (1) JP2001514660A (ja)
AT (1) ATE317224T1 (ja)
AU (1) AU726210B2 (ja)
CA (1) CA2283101C (ja)
DE (1) DE69833429T2 (ja)
EA (1) EA001797B1 (ja)
EE (1) EE03732B1 (ja)
ES (1) ES2256933T3 (ja)
ID (1) ID23656A (ja)
IS (1) IS5167A (ja)
PL (1) PL335604A1 (ja)
TR (1) TR199902242T2 (ja)
WO (1) WO1998039970A1 (ja)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE9903995D0 (sv) * 1999-11-03 1999-11-03 Astra Ab New combination
ITMI20050247A1 (it) * 2005-02-18 2006-08-19 Chemi Spa Processo per la preparazione di montelukast
KR100774088B1 (ko) * 2006-12-14 2007-11-06 한미약품 주식회사 몬테루카스트의 제조방법 및 이에 사용되는 중간체
JP2012067070A (ja) * 2010-06-25 2012-04-05 Sumitomo Chemical Co Ltd α−ケトカルボン酸の製造方法

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4920130A (en) * 1987-11-02 1990-04-24 Rorer Pharamceutical Corp. Quinoline derivatives and use thereof as antagonists of leukotriene D4
US4918081A (en) * 1988-06-20 1990-04-17 Rorer Pharmaceutical Corp. Quinoline derivatives and use thereof as antagonists of leukotriene d4
US5565473A (en) * 1990-10-12 1996-10-15 Merck Frosst Canada, Inc. Unsaturated hydroxyalkylquinoline acids as leukotriene antagonists
US5750539A (en) * 1995-06-07 1998-05-12 Merck Frosst Canada Heteroaryl diol acids as leukotriene antagonists

Also Published As

Publication number Publication date
DE69833429D1 (de) 2006-04-20
ATE317224T1 (de) 2006-02-15
WO1998039970A1 (en) 1998-09-17
PL335604A1 (en) 2000-05-08
EP0971587B1 (en) 2006-02-08
TR199902242T2 (xx) 1999-12-21
CA2283101A1 (en) 1998-09-17
EE9900406A (et) 2000-04-17
EP0971587A1 (en) 2000-01-19
EA199900824A1 (ru) 2000-04-24
EP0971587A4 (en) 2004-08-04
ID23656A (id) 2000-05-11
DE69833429T2 (de) 2006-11-09
AU6758998A (en) 1998-09-29
JP2001514660A (ja) 2001-09-11
AU726210B2 (en) 2000-11-02
ES2256933T3 (es) 2006-07-16
IS5167A (is) 1999-08-30
EA001797B1 (ru) 2001-08-27
CA2283101C (en) 2008-01-22

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Legal Events

Date Code Title Description
KB4A Valid patent at the end of a year

Effective date: 20021231

KB4A Valid patent at the end of a year

Effective date: 20031231

MM4A Lapsed by not paying the annual fees

Effective date: 20040310