ECSP22087958A - Compuestos de insulina acilada de acción temporal prolongada - Google Patents
Compuestos de insulina acilada de acción temporal prolongadaInfo
- Publication number
- ECSP22087958A ECSP22087958A ECSENADI202287958A ECDI202287958A ECSP22087958A EC SP22087958 A ECSP22087958 A EC SP22087958A EC SENADI202287958 A ECSENADI202287958 A EC SENADI202287958A EC DI202287958 A ECDI202287958 A EC DI202287958A EC SP22087958 A ECSP22087958 A EC SP22087958A
- Authority
- EC
- Ecuador
- Prior art keywords
- compounds
- acylated insulin
- long
- insulin compounds
- acting
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/575—Hormones
- C07K14/62—Insulins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/22—Hormones
- A61K38/28—Insulins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/54—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic compound
- A61K47/542—Carboxylic acids, e.g. a fatty acid or an amino acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/62—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being a protein, peptide or polyamino acid
- A61K47/65—Peptidic linkers, binders or spacers, e.g. peptidic enzyme-labile linkers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Diabetes (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Veterinary Medicine (AREA)
- Engineering & Computer Science (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Endocrinology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Epidemiology (AREA)
- Zoology (AREA)
- Gastroenterology & Hepatology (AREA)
- Biochemistry (AREA)
- Obesity (AREA)
- Genetics & Genomics (AREA)
- Biophysics (AREA)
- Toxicology (AREA)
- Emergency Medicine (AREA)
- Hematology (AREA)
- Molecular Biology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Immunology (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Abstract
Los compuestos descritos en la presente se refieren al tratamiento de la diabetes tipo I y/o tipo II y/o la hiperglucemia. Más particularmente, los compuestos descritos se refieren a compuestos de insulina acilada de acción temporal prolongada que reducen la glucosa en sangre, composiciones farmacéuticas que contienen tales compuestos, usos terapéuticos de tales compuestos y un compuesto intermediario usado para fabricar los compuestos de insulina acilada.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US202063025463P | 2020-05-15 | 2020-05-15 |
Publications (1)
Publication Number | Publication Date |
---|---|
ECSP22087958A true ECSP22087958A (es) | 2022-12-30 |
Family
ID=78524979
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ECSENADI202287958A ECSP22087958A (es) | 2020-05-15 | 2022-11-15 | Compuestos de insulina acilada de acción temporal prolongada |
Country Status (16)
Country | Link |
---|---|
US (1) | US20230174609A1 (es) |
EP (1) | EP4149516A1 (es) |
JP (1) | JP7456007B2 (es) |
KR (1) | KR20230009499A (es) |
CN (1) | CN115867308A (es) |
AU (1) | AU2021273262A1 (es) |
BR (1) | BR112022022885A2 (es) |
CA (1) | CA3177905A1 (es) |
CL (1) | CL2022003187A1 (es) |
CO (1) | CO2022016338A2 (es) |
CR (1) | CR20220641A (es) |
EC (1) | ECSP22087958A (es) |
IL (1) | IL297976A (es) |
MX (1) | MX2022014309A (es) |
PE (1) | PE20230832A1 (es) |
WO (1) | WO2021231676A1 (es) |
Families Citing this family (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN116162147B (zh) * | 2021-11-24 | 2023-10-03 | 成都奥达生物科技有限公司 | 一种长效胰岛素类似物 |
CN115850385B (zh) * | 2022-07-04 | 2023-08-11 | 北京惠之衡生物科技有限公司 | 一种促表达肽及其应用 |
CN115894719B (zh) * | 2022-11-24 | 2023-10-20 | 武汉禾元生物科技股份有限公司 | 一种人血清白蛋白胰岛素偶联物及其制备方法 |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5693609A (en) * | 1994-11-17 | 1997-12-02 | Eli Lilly And Company | Acylated insulin analogs |
BR9813111A (pt) | 1997-10-24 | 2000-08-15 | Lilly Co Eli | Composições de insulina insolúveis |
US6444641B1 (en) * | 1997-10-24 | 2002-09-03 | Eli Lilly Company | Fatty acid-acylated insulin analogs |
US20170008928A1 (en) | 2015-07-06 | 2017-01-12 | Novo Nordisk A/S | Novel peptides and peptide derivatives and uses thereof |
JOP20190273A1 (ar) * | 2017-05-26 | 2019-11-24 | Lilly Co Eli | مركب إنسولين معالج بأسيل |
-
2021
- 2021-05-13 AU AU2021273262A patent/AU2021273262A1/en active Pending
- 2021-05-13 CN CN202180049612.8A patent/CN115867308A/zh active Pending
- 2021-05-13 US US17/998,090 patent/US20230174609A1/en active Pending
- 2021-05-13 KR KR1020227043481A patent/KR20230009499A/ko active Search and Examination
- 2021-05-13 CR CR20220641A patent/CR20220641A/es unknown
- 2021-05-13 CA CA3177905A patent/CA3177905A1/en active Pending
- 2021-05-13 IL IL297976A patent/IL297976A/en unknown
- 2021-05-13 BR BR112022022885A patent/BR112022022885A2/pt unknown
- 2021-05-13 MX MX2022014309A patent/MX2022014309A/es unknown
- 2021-05-13 JP JP2022569032A patent/JP7456007B2/ja active Active
- 2021-05-13 WO PCT/US2021/032144 patent/WO2021231676A1/en active Application Filing
- 2021-05-13 EP EP21805284.3A patent/EP4149516A1/en active Pending
- 2021-05-13 PE PE2022002656A patent/PE20230832A1/es unknown
-
2022
- 2022-11-15 CO CONC2022/0016338A patent/CO2022016338A2/es unknown
- 2022-11-15 EC ECSENADI202287958A patent/ECSP22087958A/es unknown
- 2022-11-15 CL CL2022003187A patent/CL2022003187A1/es unknown
Also Published As
Publication number | Publication date |
---|---|
EP4149516A1 (en) | 2023-03-22 |
US20230174609A1 (en) | 2023-06-08 |
CN115867308A (zh) | 2023-03-28 |
BR112022022885A2 (pt) | 2022-12-20 |
CO2022016338A2 (es) | 2022-11-29 |
AU2021273262A1 (en) | 2022-12-08 |
IL297976A (en) | 2023-01-01 |
KR20230009499A (ko) | 2023-01-17 |
CL2022003187A1 (es) | 2023-03-03 |
WO2021231676A1 (en) | 2021-11-18 |
JP7456007B2 (ja) | 2024-03-26 |
JP2023526069A (ja) | 2023-06-20 |
CA3177905A1 (en) | 2021-11-18 |
MX2022014309A (es) | 2022-12-07 |
CR20220641A (es) | 2023-01-19 |
PE20230832A1 (es) | 2023-05-19 |
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