ECSP109889A - Composiciones terapeuticas y usos de las mismas - Google Patents

Composiciones terapeuticas y usos de las mismas

Info

Publication number
ECSP109889A
ECSP109889A EC2010009889A ECSP109889A ECSP109889A EC SP109889 A ECSP109889 A EC SP109889A EC 2010009889 A EC2010009889 A EC 2010009889A EC SP109889 A ECSP109889 A EC SP109889A EC SP109889 A ECSP109889 A EC SP109889A
Authority
EC
Ecuador
Prior art keywords
same
therapeutic compositions
pharmaceutically acceptable
acceptable salt
compositions
Prior art date
Application number
EC2010009889A
Other languages
English (en)
Spanish (es)
Inventor
Brian P Kearney
Anita A Mathias
Original Assignee
Gilead Sciences Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Gilead Sciences Inc filed Critical Gilead Sciences Inc
Publication of ECSP109889A publication Critical patent/ECSP109889A/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/425—Thiazoles
    • A61K31/426—1,3-Thiazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/513—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim having oxo groups directly attached to the heterocyclic ring, e.g. cytosine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
    • A61K31/5375—1,4-Oxazines, e.g. morpholine
    • A61K31/5377—1,4-Oxazines, e.g. morpholine not condensed and containing further heterocyclic rings, e.g. timolol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/06—Tripeptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/18—Antivirals for RNA viruses for HIV
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Virology (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • AIDS & HIV (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Molecular Biology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
EC2010009889A 2007-06-29 2010-01-21 Composiciones terapeuticas y usos de las mismas ECSP109889A (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US94732507P 2007-06-29 2007-06-29

Publications (1)

Publication Number Publication Date
ECSP109889A true ECSP109889A (es) 2010-03-31

Family

ID=39817166

Family Applications (1)

Application Number Title Priority Date Filing Date
EC2010009889A ECSP109889A (es) 2007-06-29 2010-01-21 Composiciones terapeuticas y usos de las mismas

Country Status (21)

Country Link
US (4) US20110009411A1 (cg-RX-API-DMAC7.html)
EP (1) EP2167089A1 (cg-RX-API-DMAC7.html)
JP (3) JP5547067B2 (cg-RX-API-DMAC7.html)
KR (1) KR20100028656A (cg-RX-API-DMAC7.html)
CN (2) CN103356622A (cg-RX-API-DMAC7.html)
AP (1) AP2490A (cg-RX-API-DMAC7.html)
AR (1) AR067184A1 (cg-RX-API-DMAC7.html)
AU (1) AU2008270634B2 (cg-RX-API-DMAC7.html)
BR (1) BRPI0813955A2 (cg-RX-API-DMAC7.html)
CA (1) CA2691736A1 (cg-RX-API-DMAC7.html)
CO (1) CO6251236A2 (cg-RX-API-DMAC7.html)
EA (1) EA200971096A1 (cg-RX-API-DMAC7.html)
EC (1) ECSP109889A (cg-RX-API-DMAC7.html)
IL (1) IL202745A0 (cg-RX-API-DMAC7.html)
MX (1) MX2009013828A (cg-RX-API-DMAC7.html)
NZ (1) NZ582089A (cg-RX-API-DMAC7.html)
SG (1) SG182228A1 (cg-RX-API-DMAC7.html)
TW (1) TW200916103A (cg-RX-API-DMAC7.html)
UA (1) UA103881C2 (cg-RX-API-DMAC7.html)
WO (1) WO2009006203A1 (cg-RX-API-DMAC7.html)
ZA (1) ZA201000468B (cg-RX-API-DMAC7.html)

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HRP20080313A2 (en) * 2005-12-30 2008-11-30 Gilead Sciences Methods for improving the pharmacokinetics of hiv integrase inhibitors
EP4566670A3 (en) 2006-07-07 2025-08-27 Gilead Sciences, Inc. Modulators of pharmacokinetic properties of therapeutics
SG10201501782UA (en) 2006-09-12 2015-05-28 Gilead Sciences Inc Process and intermediates for preparing integrase inhibitors
AP3915A (en) * 2007-02-23 2016-11-29 Gilead Sciences Inc Modulators of pharmacokinetic properties of therapeutics
KR20100040892A (ko) * 2007-06-29 2010-04-21 길리애드 사이언시즈, 인코포레이티드 치료 조성물 및 그의 용도
AR068403A1 (es) 2007-09-11 2009-11-18 Gilead Sciences Inc Proceso e intermediarios para la preparacion de inhibidores de integrasa
HRP20151357T1 (hr) 2008-05-02 2016-01-29 Gilead Sciences, Inc. Upotreba äśestica äśvrstog nosaäśa kako bi se poboljšala procesabilnost farmaceutskog agensa
ES2582877T3 (es) * 2010-04-09 2016-09-15 Bristol-Myers Squibb Holdings Ireland Formulaciones de sulfato de atazanavir con un efecto de pH mejorado
WO2012088178A1 (en) * 2010-12-21 2012-06-28 Gilead Sciences, Inc. Inhibitors of cytochrome p450 (cyp3a4)
EP3750544B1 (en) 2011-11-30 2025-03-05 Emory University Jak inhibitors for use in the prevention or treatment of a viral disease caused by a coronaviridae
AU2013225981A1 (en) * 2012-03-01 2014-10-02 Gilead Sciences, Inc. Spray dried formulations
CA2878699C (en) 2012-08-03 2018-09-11 Gilead Sciences, Inc. Process and intermediates for preparing integrase inhibitors
CN107674086B (zh) 2012-12-21 2020-03-31 吉利德科学公司 多环-氨基甲酰基吡啶酮化合物及其药物用途
NO2865735T3 (cg-RX-API-DMAC7.html) 2013-07-12 2018-07-21
PL3252058T3 (pl) 2013-07-12 2021-07-19 Gilead Sciences, Inc. Policykliczne związki karbamoilopirydonowe i ich zastosowanie do leczenia infekcji hiv
NO2717902T3 (cg-RX-API-DMAC7.html) 2014-06-20 2018-06-23
TW201613936A (en) 2014-06-20 2016-04-16 Gilead Sciences Inc Crystalline forms of(2R,5S,13aR)-8-hydroxy-7,9-dioxo-n-(2,4,6-trifluorobenzyl)-2,3,4,5,7,9,13,13a-octahydro-2,5-methanopyrido[1',2':4,5]pyrazino[2,1-b][1,3]oxazepine-10-carboxamide
TWI744723B (zh) 2014-06-20 2021-11-01 美商基利科學股份有限公司 多環型胺甲醯基吡啶酮化合物之合成
TWI695003B (zh) 2014-12-23 2020-06-01 美商基利科學股份有限公司 多環胺甲醯基吡啶酮化合物及其醫藥用途
IL296496B2 (en) 2014-12-26 2024-10-01 Univ Emory N4-hydroxycytidine and derivatives and anti-viral uses related thereto
HK1249103B (en) 2015-04-02 2020-02-07 Gilead Sciences, Inc. Polycyclic-carbamoylpyridone compounds and their pharmaceutical use
RS66222B1 (sr) 2017-12-07 2024-12-31 Univ Emory N4-hidroksicitidin i derivati i antivirusne upotrebe povezane sa njim

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US5696270A (en) * 1989-05-23 1997-12-09 Abbott Laboratories Intermediate for making retroviral protease inhibiting compounds
GB8927913D0 (en) * 1989-12-11 1990-02-14 Hoffmann La Roche Amino acid derivatives
US5413999A (en) * 1991-11-08 1995-05-09 Merck & Co., Inc. HIV protease inhibitors useful for the treatment of AIDS
US5484926A (en) * 1993-10-07 1996-01-16 Agouron Pharmaceuticals, Inc. HIV protease inhibitors
US5914332A (en) * 1995-12-13 1999-06-22 Abbott Laboratories Retroviral protease inhibiting compounds
US5849911A (en) * 1996-04-22 1998-12-15 Novartis Finance Corporation Antivirally active heterocyclic azahexane derivatives
US6087383A (en) * 1998-01-20 2000-07-11 Bristol-Myers Squibb Company Bisulfate salt of HIV protease inhibitor
KR100665919B1 (ko) * 2002-11-20 2007-03-08 니뽄 다바코 산교 가부시키가이샤 4-옥소퀴놀린 화합물 및 ｈｉｖ 인테그라제 저해제로서의그의 용도
US20060111933A1 (en) * 2003-10-09 2006-05-25 Steven Wheeler Adaptive medical decision support system
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EP3287130A1 (en) * 2004-05-21 2018-02-28 Japan Tobacco Inc. Combinations comprising a 4-isoquinolone derivative and protease inhibitors
US20060058286A1 (en) * 2004-09-16 2006-03-16 Mark Krystal Methods of treating HIV infection
US20090233964A1 (en) * 2005-12-30 2009-09-17 Gilead Sciences, Inc. Methods for improving the pharmacokinetics of hiv integrase inhibitors
HRP20080313A2 (en) * 2005-12-30 2008-11-30 Gilead Sciences Methods for improving the pharmacokinetics of hiv integrase inhibitors
WO2007092802A1 (en) * 2006-02-09 2007-08-16 Boehringer Ingelheim International Gmbh Method for treating hiv infection through co-administration of tipranavir and gs 9137
EP4566670A3 (en) * 2006-07-07 2025-08-27 Gilead Sciences, Inc. Modulators of pharmacokinetic properties of therapeutics
SG10201501782UA (en) * 2006-09-12 2015-05-28 Gilead Sciences Inc Process and intermediates for preparing integrase inhibitors
KR20100040892A (ko) * 2007-06-29 2010-04-21 길리애드 사이언시즈, 인코포레이티드 치료 조성물 및 그의 용도
AR068403A1 (es) * 2007-09-11 2009-11-18 Gilead Sciences Inc Proceso e intermediarios para la preparacion de inhibidores de integrasa
HRP20151357T1 (hr) * 2008-05-02 2016-01-29 Gilead Sciences, Inc. Upotreba äśestica äśvrstog nosaäśa kako bi se poboljšala procesabilnost farmaceutskog agensa
US20110000941A1 (en) * 2009-07-06 2011-01-06 Volk J Patrick Apparatus and System for Carrying a Digital Media Player

Also Published As

Publication number Publication date
ZA201000468B (en) 2011-06-29
JP5547067B2 (ja) 2014-07-09
CN101743004A (zh) 2010-06-16
AP2490A (en) 2012-10-04
JP2013199494A (ja) 2013-10-03
US20140343062A1 (en) 2014-11-20
WO2009006203A1 (en) 2009-01-08
AP2009005083A0 (en) 2009-12-31
CO6251236A2 (es) 2011-02-21
EP2167089A1 (en) 2010-03-31
TW200916103A (en) 2009-04-16
CN103356622A (zh) 2013-10-23
AU2008270634B2 (en) 2014-01-16
BRPI0813955A2 (pt) 2017-05-09
KR20100028656A (ko) 2010-03-12
IL202745A0 (en) 2010-06-30
JP5769762B2 (ja) 2015-08-26
MX2009013828A (es) 2010-03-10
EA200971096A1 (ru) 2010-08-30
AR067184A1 (es) 2009-09-30
UA103881C2 (ru) 2013-12-10
SG182228A1 (en) 2012-07-30
NZ582089A (en) 2013-01-25
US20170136000A1 (en) 2017-05-18
AU2008270634A1 (en) 2009-01-08
CA2691736A1 (en) 2009-01-08
US20110009411A1 (en) 2011-01-13
US20090093482A1 (en) 2009-04-09
JP2010532373A (ja) 2010-10-07
JP2015143277A (ja) 2015-08-06

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