EA202192954A1 - Электрохимическое измерение d-лактата для диагностики и прогнозирования инфекционного заболевания - Google Patents
Электрохимическое измерение d-лактата для диагностики и прогнозирования инфекционного заболеванияInfo
- Publication number
- EA202192954A1 EA202192954A1 EA202192954A EA202192954A EA202192954A1 EA 202192954 A1 EA202192954 A1 EA 202192954A1 EA 202192954 A EA202192954 A EA 202192954A EA 202192954 A EA202192954 A EA 202192954A EA 202192954 A1 EA202192954 A1 EA 202192954A1
- Authority
- EA
- Eurasian Patent Office
- Prior art keywords
- lactate
- infectious disease
- level
- diagnostics
- prediction
- Prior art date
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- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Organic Chemistry (AREA)
- Immunology (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Hematology (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- Biotechnology (AREA)
- Microbiology (AREA)
- Biophysics (AREA)
- Urology & Nephrology (AREA)
- Biomedical Technology (AREA)
- General Engineering & Computer Science (AREA)
- Genetics & Genomics (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
- Cell Biology (AREA)
- Medicinal Chemistry (AREA)
- Food Science & Technology (AREA)
- Diabetes (AREA)
- Toxicology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Electrochemistry (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Apparatus Associated With Microorganisms And Enzymes (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Abstract
Изобретение относится к in vitro способу диагностики, прогнозирования, оценки риска, мониторинга, терапевтического ведения и/или терапевтического контроля инфекционного заболевания, включающему (a) обеспечение образца субъекта, проявляющего клинические симптомы инфекции и/или подозреваемого на наличие инфекции, (b) определение уровня D-лактата в указанном образце, (c) при этом уровень D-лактата указывает на наличие инфекционного заболевания, отличающемуся тем, что (d) уровень D-лактата в указанном образце определяют с помощью электрохимической сенсорной системы (биосенсора). Согласно вариантам осуществления электрохимическая сенсорная система содержит потенциометрический или амперометрический сенсор. Предпочтительно электрохимическая система содержит связывающую D-лактат молекулу, которая предпочтительно иммобилизована на электроде определения (рабочем). Согласно вариантам осуществления электрод определения с иммобилизованной связывающей D-лактат молекулой состоит из (одноразовой) тест-полоски для вставки в портативное устройство считывания.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP19171761 | 2019-04-30 | ||
| PCT/EP2020/061999 WO2020221847A1 (en) | 2019-04-30 | 2020-04-30 | Electrochemical d-lactate measurement for diagnosis and prognosis of an infectious disease |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| EA202192954A1 true EA202192954A1 (ru) | 2022-03-18 |
Family
ID=66625732
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| EA202192954A EA202192954A1 (ru) | 2019-04-30 | 2020-04-30 | Электрохимическое измерение d-лактата для диагностики и прогнозирования инфекционного заболевания |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US20220206009A1 (ru) |
| EP (1) | EP3963327A1 (ru) |
| JP (1) | JP2022531767A (ru) |
| CN (1) | CN113767288A (ru) |
| CA (1) | CA3137620A1 (ru) |
| EA (1) | EA202192954A1 (ru) |
| IL (1) | IL287582A (ru) |
| WO (1) | WO2020221847A1 (ru) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2023110190A1 (en) * | 2021-12-13 | 2023-06-22 | Heraeus Medical Gmbh | Tests and methods for detecting bacterial infection |
| CN114778629B (zh) * | 2022-04-28 | 2023-10-20 | 孟栋栋 | 一种用于医疗内分泌科临床抽血检测装置 |
| EP4357778A1 (en) * | 2022-10-20 | 2024-04-24 | Heraeus Medical GmbH | Treatment of microbial infections diagnosed using the biomarker d-lactate |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20120143027A1 (en) | 2007-12-19 | 2012-06-07 | Kimberly-Clark Worldwide, Inc. | Field effect transistors for detection of nosocomial infection |
| JP5684767B2 (ja) * | 2011-09-26 | 2015-03-18 | アークレイ株式会社 | 乳酸センサ |
| GB201510765D0 (en) * | 2015-06-18 | 2015-08-05 | Inside Biometrics Ltd | Method, apparatus and electrochemical test device |
| RU2642659C1 (ru) * | 2016-09-26 | 2018-01-25 | федеральное государственное бюджетное учреждение "Федеральный центр травматологии, ортопедии и эндопротезирования" Министерства здравоохранения Российской Федерации (г. Барнаул) | Способ диагностики перипротезной инфекции суставов |
| EP3682239B1 (en) * | 2017-09-13 | 2023-03-22 | Alio, Inc. | Systems and methods for detecting a periprosthetic infection |
-
2020
- 2020-04-30 EA EA202192954A patent/EA202192954A1/ru unknown
- 2020-04-30 EP EP20721615.1A patent/EP3963327A1/en active Pending
- 2020-04-30 US US17/606,541 patent/US20220206009A1/en active Pending
- 2020-04-30 CA CA3137620A patent/CA3137620A1/en active Pending
- 2020-04-30 CN CN202080032409.5A patent/CN113767288A/zh active Pending
- 2020-04-30 WO PCT/EP2020/061999 patent/WO2020221847A1/en unknown
- 2020-04-30 JP JP2021564793A patent/JP2022531767A/ja active Pending
-
2021
- 2021-10-26 IL IL287582A patent/IL287582A/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| IL287582A (en) | 2021-12-01 |
| WO2020221847A1 (en) | 2020-11-05 |
| CA3137620A1 (en) | 2020-11-05 |
| EP3963327A1 (en) | 2022-03-09 |
| JP2022531767A (ja) | 2022-07-11 |
| CN113767288A (zh) | 2021-12-07 |
| US20220206009A1 (en) | 2022-06-30 |
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