EA202091736A1 - Применение колхицина для ингибирования роста опухоли и метастазов - Google Patents

Применение колхицина для ингибирования роста опухоли и метастазов

Info

Publication number
EA202091736A1
EA202091736A1 EA202091736A EA202091736A EA202091736A1 EA 202091736 A1 EA202091736 A1 EA 202091736A1 EA 202091736 A EA202091736 A EA 202091736A EA 202091736 A EA202091736 A EA 202091736A EA 202091736 A1 EA202091736 A1 EA 202091736A1
Authority
EA
Eurasian Patent Office
Prior art keywords
metastases
inhibiting
growth
collchicine
tumor
Prior art date
Application number
EA202091736A
Other languages
English (en)
Russian (ru)
Inventor
Майкл Риэль
Original Assignee
Марри Энд Пул Энтерпрайзес, Лтд.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Марри Энд Пул Энтерпрайзес, Лтд. filed Critical Марри Энд Пул Энтерпрайзес, Лтд.
Publication of EA202091736A1 publication Critical patent/EA202091736A1/ru

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/16—Amides, e.g. hydroxamic acids
    • A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2009—Inorganic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2013—Organic compounds, e.g. phospholipids, fats
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2013—Organic compounds, e.g. phospholipids, fats
    • A61K9/2018—Sugars, or sugar alcohols, e.g. lactose, mannitol; Derivatives thereof, e.g. polysorbates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2059—Starch, including chemically or physically modified derivatives; Amylose; Amylopectin; Dextrin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/04—Antineoplastic agents specific for metastasis

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Oncology (AREA)
  • Inorganic Chemistry (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
EA202091736A 2018-02-02 2019-02-01 Применение колхицина для ингибирования роста опухоли и метастазов EA202091736A1 (ru)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201862625354P 2018-02-02 2018-02-02
PCT/EP2019/052492 WO2019149884A1 (en) 2018-02-02 2019-02-01 Use of colchicine to inhibit tumor growth and metastases

Publications (1)

Publication Number Publication Date
EA202091736A1 true EA202091736A1 (ru) 2020-10-19

Family

ID=65278359

Family Applications (1)

Application Number Title Priority Date Filing Date
EA202091736A EA202091736A1 (ru) 2018-02-02 2019-02-01 Применение колхицина для ингибирования роста опухоли и метастазов

Country Status (7)

Country Link
US (3) US11534415B2 (https=)
EP (1) EP3746061A1 (https=)
JP (3) JP2022514997A (https=)
CN (1) CN111954524A (https=)
CA (1) CA3089781A1 (https=)
EA (1) EA202091736A1 (https=)
WO (1) WO2019149884A1 (https=)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2021089715A1 (en) * 2019-11-06 2021-05-14 Murray And Poole Enterprises, Ltd. Use of colchicine in the treatment and prevention of lung cancer
CN115068483B (zh) * 2021-03-16 2023-10-31 中国科学院上海药物研究所 Mln4924在缓解秋水仙碱中毒中的新用途

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3173876A (en) 1960-05-27 1965-03-16 John C Zobrist Cleaning methods and compositions
US3276586A (en) 1963-08-30 1966-10-04 Rosaen Filter Co Indicating means for fluid filters
US3546142A (en) 1967-01-19 1970-12-08 Amicon Corp Polyelectrolyte structures
US3541006A (en) 1968-07-03 1970-11-17 Amicon Corp Ultrafiltration process
US3541005A (en) 1969-02-05 1970-11-17 Amicon Corp Continuous ultrafiltration of macromolecular solutions
US4285987A (en) 1978-10-23 1981-08-25 Alza Corporation Process for manufacturing device with dispersion zone
CA2286477A1 (en) 1997-04-11 1998-10-22 Dendreon Corporation Composition and method for inducing an immune response against tumour-related antigens
CN1748671A (zh) * 2005-08-30 2006-03-22 孔庆忠 含抗有丝分裂药物的缓释注射剂
CN101485637B (zh) * 2008-01-18 2011-03-30 普尔药物科技开发（深圳）有限公司 秋水仙碱骨架控释片或胶囊
JP6356684B2 (ja) 2012-11-02 2018-07-11 マレイ・アンド・プール・エンタープライゼズ・リミテッド コルヒチン誘導体の投与による心血管イベントの処置または予防
CA2909370A1 (en) * 2013-04-16 2014-10-23 Murray And Poole Enterprises Limited Sustained-release formulations of colchicine and methods of using same
IL292510A (en) 2013-11-05 2022-06-01 Cognate Bioservices Inc Combinations of checkpoint inhibitors and therapeutics to treat cancer

Also Published As

Publication number Publication date
US20230137776A1 (en) 2023-05-04
US20240099999A1 (en) 2024-03-28
JP2025134752A (ja) 2025-09-17
CN111954524A (zh) 2020-11-17
US11534415B2 (en) 2022-12-27
WO2019149884A1 (en) 2019-08-08
JP2022514997A (ja) 2022-02-17
EP3746061A1 (en) 2020-12-09
US20210046024A1 (en) 2021-02-18
JP2024050581A (ja) 2024-04-10
CA3089781A1 (en) 2019-08-08
US11877991B2 (en) 2024-01-23

Similar Documents

Publication Publication Date Title
MX2019013954A (es) Inhibidores covalentes de kras.
MX2021005012A (es) Compuestos, composiciones farmacéuticas y métodos de preparación de compuestos y de su uso como inhibidores de la cinasa atr.
EP4685160A3 (en) Combination therapy including a krasg12c inhibitor and one or more additional pharmaceutically active agents for the treatment of cancers
MX2024013597A (es) Composiciones de nanoparticulas lipidicas para suministro de agentes biologicamente activos
MX2024000349A (es) Compuestos y usos de los mismos.
CL2018002924A1 (es) Inhibidores de bromodominios
MX2021004639A (es) Combinaciones de inhibidores de desmetilasa-1 especifica de lisina (lsd1) para uso en el tratamiento de tumores solidos.
CY1118731T1 (el) Φαρμακευτικες συνθεσεις αλβιγλουτιδης
MX380928B (es) Inhibidores de kras g12c.
MX2022014457A (es) Formulaciones de inmunoconjugado anti-cd79b estables.
EA201990424A1 (ru) Спиролактамовые модуляторы nmda-рецептора и их применение
MX2024002989A (es) Formulaciones de 4-(7-hidroxi-2-isopropil-4-oxo-4h-quinazolin-3-il )-benzonitrilo.
PH12019502150A1 (en) Compounds and methods for the treatment of parasitic diseases
EA201990428A1 (ru) Спиролактамовые модуляторы nmda-рецептора и их применение
EA202192047A1 (ru) Соединения и их применение
MX393900B (es) Uso de gaboxadol en el tratamiento de tinnitus.
JOP20220160A1 (ar) مركبات فعّالة نحو مستقبلات نووية
EA202190057A1 (ru) Солюбилизированные апиразы, способы и применение
WO2018033941A3 (en) Pharmaceutical compositions of ibrutinib
SA520420261B1 (ar) تركيبات إرنوماب واستخداماتها
MX2022006312A (es) Inhibidores del receptor de hidrocarburos de arilo (ahr) y usos de los mismos.
EA202091736A1 (ru) Применение колхицина для ингибирования роста опухоли и метастазов
EA202090424A1 (ru) Бициклические ингибиторы гистондеацетилазы
MX2019004375A (es) Inhibidores de bromodominios.
UY37412A (es) Compuestos de indazol para uso en lesiones de tendones y/o ligamentos