EA202090735A1 - Составы хлорпрокаина для местного применения и способы их применения - Google Patents

Составы хлорпрокаина для местного применения и способы их применения

Info

Publication number
EA202090735A1
EA202090735A1 EA202090735A EA202090735A EA202090735A1 EA 202090735 A1 EA202090735 A1 EA 202090735A1 EA 202090735 A EA202090735 A EA 202090735A EA 202090735 A EA202090735 A EA 202090735A EA 202090735 A1 EA202090735 A1 EA 202090735A1
Authority
EA
Eurasian Patent Office
Prior art keywords
compositions
methods
chloroprocine
local
dosages
Prior art date
Application number
EA202090735A
Other languages
English (en)
Inventor
Аугусто Митидьери
Элизабетта Донати
Клара Бьянки
Original Assignee
Синтетика С.А.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Синтетика С.А. filed Critical Синтетика С.А.
Publication of EA202090735A1 publication Critical patent/EA202090735A1/ru

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/06—Ointments; Bases therefor; Other semi-solid forms, e.g. creams, sticks, gels
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • A61K31/235—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids having an aromatic ring attached to a carboxyl group
    • A61K31/24—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids having an aromatic ring attached to a carboxyl group having an amino or nitro group
    • A61K31/245—Amino benzoic acid types, e.g. procaine, novocaine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/02—Inorganic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/12—Carboxylic acids; Salts or anhydrides thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • A61K47/38—Cellulose; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0048—Eye, e.g. artificial tears
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P23/00—Anaesthetics
    • A61P23/02—Local anaesthetics

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Anesthesiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Inorganic Chemistry (AREA)
  • Ophthalmology & Optometry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Emergency Medicine (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

Представлены дозировки и составы хлорпрокаина для местного применения, включая гели и мази, и способы их изготовления и применения, которые являются эффективными, химически стабильными и физиологически сбалансированными в отношении безопасности и эффективности. Дозировки и составы являются особенно пригодными в ходе офтальмологических процедур и при офтальмологических истираниях или травме, исходя из их переносимости и фармакокинетики.
EA202090735A 2017-09-15 2018-09-14 Составы хлорпрокаина для местного применения и способы их применения EA202090735A1 (ru)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201762559220P 2017-09-15 2017-09-15
PCT/IB2018/057073 WO2019053657A1 (en) 2017-09-15 2018-09-14 TOPICAL FORMULATIONS OF CHLOROPROCAINE

Publications (1)

Publication Number Publication Date
EA202090735A1 true EA202090735A1 (ru) 2020-06-22

Family

ID=63713967

Family Applications (1)

Application Number Title Priority Date Filing Date
EA202090735A EA202090735A1 (ru) 2017-09-15 2018-09-14 Составы хлорпрокаина для местного применения и способы их применения

Country Status (23)

Country Link
US (3) US10792271B2 (ru)
EP (1) EP3681473A1 (ru)
JP (1) JP2020533321A (ru)
KR (1) KR20200053476A (ru)
CN (1) CN111163756B (ru)
AU (1) AU2018332212B2 (ru)
BR (1) BR112020003095A2 (ru)
CA (1) CA3070336C (ru)
CL (1) CL2020000665A1 (ru)
CO (1) CO2020002985A2 (ru)
CR (1) CR20200133A (ru)
CU (1) CU20200019A7 (ru)
EA (1) EA202090735A1 (ru)
EC (1) ECSP20022313A (ru)
IL (1) IL273213A (ru)
JO (1) JOP20200010A1 (ru)
MA (1) MA50241A (ru)
MX (1) MX2020002898A (ru)
PE (1) PE20201281A1 (ru)
PH (1) PH12020550029A1 (ru)
SG (1) SG11202000992RA (ru)
WO (1) WO2019053657A1 (ru)
ZA (1) ZA202000601B (ru)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TW202139993A (zh) * 2020-03-16 2021-11-01 瑞士商辛鐵堤卡公司 具有經改良之功能性的眼用氯普魯卡因(chloroprocaine)凝膠

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6218428B1 (en) * 2000-04-28 2001-04-17 Emil Chynn Ophthalmic composition
JP2004123634A (ja) * 2002-10-03 2004-04-22 Lion Corp 眼科用組成物
JP2006513224A (ja) * 2002-12-20 2006-04-20 ザ・ボード・オブ・トラスティーズ・オブ・ザ・レランド・スタンフォード・ジュニア・ユニバーシティ エステル局所麻酔薬の組み合わせ
US20050137177A1 (en) * 2003-12-18 2005-06-23 Shafer Steven L. Ester combination local anesthetic
CA2596194A1 (en) * 2004-11-24 2006-06-01 Algorx Pharmaceuticals, Inc. Capsaicinoid gel formulation and uses thereof
ITMI20051633A1 (it) 2005-09-06 2007-03-07 Sint Sa Nuovo uso di una composizione comprendente cloroprocaina hcl nuova composizione comprendente cloroprocaina hcl e metodo per la sua fabbricazione
CN103405576B (zh) * 2013-08-23 2016-03-30 何学忠 一种治疗由焊接强光辐射引起的眼部疾病的滴眼液

Also Published As

Publication number Publication date
US20240216323A1 (en) 2024-07-04
CA3070336C (en) 2022-08-23
SG11202000992RA (en) 2020-03-30
MA50241A (fr) 2020-07-22
PH12020550029A1 (en) 2021-02-08
CL2020000665A1 (es) 2020-09-21
CU20200019A7 (es) 2020-11-30
ECSP20022313A (es) 2020-07-31
BR112020003095A2 (pt) 2020-08-25
CN111163756B (zh) 2022-04-15
CO2020002985A2 (es) 2020-05-29
PE20201281A1 (es) 2020-11-24
JP2020533321A (ja) 2020-11-19
CA3070336A1 (en) 2019-03-21
CN111163756A (zh) 2020-05-15
CR20200133A (es) 2020-05-09
US10792271B2 (en) 2020-10-06
JOP20200010A1 (ar) 2022-10-30
US11969403B2 (en) 2024-04-30
EP3681473A1 (en) 2020-07-22
WO2019053657A1 (en) 2019-03-21
US20200390738A1 (en) 2020-12-17
IL273213A (en) 2020-04-30
ZA202000601B (en) 2021-02-24
AU2018332212B2 (en) 2023-03-16
AU2018332212A1 (en) 2020-02-27
US20190083446A1 (en) 2019-03-21
MX2020002898A (es) 2020-11-06
KR20200053476A (ko) 2020-05-18

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