EA201991166A1 - Ректальный инсулин для лечения воспалительных заболеваний кишечника - Google Patents

Ректальный инсулин для лечения воспалительных заболеваний кишечника

Info

Publication number
EA201991166A1
EA201991166A1 EA201991166A EA201991166A EA201991166A1 EA 201991166 A1 EA201991166 A1 EA 201991166A1 EA 201991166 A EA201991166 A EA 201991166A EA 201991166 A EA201991166 A EA 201991166A EA 201991166 A1 EA201991166 A1 EA 201991166A1
Authority
EA
Eurasian Patent Office
Prior art keywords
treatment
intestine
inflammatory diseases
insulin
rectal insulin
Prior art date
Application number
EA201991166A
Other languages
English (en)
Inventor
Йорген Олсен
Мохаммад Таха Яссин
Андерс Педерсен Элм
Original Assignee
Юниверсити Оф Копенгаген
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Юниверсити Оф Копенгаген filed Critical Юниверсити Оф Копенгаген
Publication of EA201991166A1 publication Critical patent/EA201991166A1/ru

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/22—Hormones
    • A61K38/28—Insulins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0031—Rectum, anus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Endocrinology (AREA)
  • Diabetes (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

Настоящее раскрытие относится к композициям, содержащим инсулин и подлежащим ректальному введению для лечения воспалительных заболеваний кишечника и вызванной воспалением опухоли и/или рака ободочной и прямой кишок.
EA201991166A 2016-11-14 2017-11-10 Ректальный инсулин для лечения воспалительных заболеваний кишечника EA201991166A1 (ru)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP16198633 2016-11-14
PCT/EP2017/078900 WO2018087298A1 (en) 2016-11-14 2017-11-10 Rectal insulin for treatment of inflammatory bowel diseases

Publications (1)

Publication Number Publication Date
EA201991166A1 true EA201991166A1 (ru) 2019-09-30

Family

ID=57321168

Family Applications (1)

Application Number Title Priority Date Filing Date
EA201991166A EA201991166A1 (ru) 2016-11-14 2017-11-10 Ректальный инсулин для лечения воспалительных заболеваний кишечника

Country Status (9)

Country Link
US (1) US11400137B2 (ru)
EP (1) EP3538132B1 (ru)
CA (1) CA3041390A1 (ru)
DK (1) DK3538132T3 (ru)
EA (1) EA201991166A1 (ru)
ES (1) ES2850650T3 (ru)
PL (1) PL3538132T3 (ru)
PT (1) PT3538132T (ru)
WO (1) WO2018087298A1 (ru)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN110809484B (zh) 2017-06-29 2022-07-12 阿森迪斯药物股份有限公司 具有重构处理支承件的自动注射器
JP7017198B2 (ja) * 2018-06-22 2022-02-08 株式会社Ａｉメディカルサービス 消化器官の内視鏡画像による疾患の診断支援方法、診断支援システム、診断支援プログラム及びこの診断支援プログラムを記憶したコンピュータ読み取り可能な記録媒体
EP3941479A1 (en) 2019-03-20 2022-01-26 Reponex Pharmaceuticals A/S Targeting biological agents to mucosal defects of the gastrointestinal tract

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2051574B (en) 1979-05-10 1984-01-18 Kyoto Pharma Ind Adjuvant for promoting absorption of pharmacologically active substances through the rectum
US4406896A (en) 1979-12-20 1983-09-27 Merck & Co., Inc. Adjuvants for rectal delivery of drug substances
JP2921872B2 (ja) * 1989-08-28 1999-07-19 和光純薬工業株式会社 経粘膜製剤
WO1996020001A1 (fr) 1994-12-28 1996-07-04 Teikoku Hormone Mfg. Co., Ltd. Preparation traversant la muqueuse
KR970064597A (ko) 1996-03-21 1997-10-13 황규언 위장장애 또는 위산분해가 있는 약물의 직장투여용 조성물
CA2406947A1 (en) * 2000-04-19 2001-10-25 Johns Hopkins University Methods for prevention and treatment of gastrointestinal disorders
US20040037828A1 (en) 2002-07-09 2004-02-26 Bar-Ilan University Methods and pharmaceutical compositions for healing wounds
CA2447693A1 (en) 2001-05-31 2002-12-05 Cima Labs Inc. Taste-masking of highly water-soluble drugs
US20070219131A1 (en) 2004-04-15 2007-09-20 Ben-Sasson Shmuel A Compositions capable of facilitating penetration across a biological barrier
US8026211B2 (en) * 2004-06-02 2011-09-27 Technion Research & Development Foundation Ltd. Methods and formulations for increasing intestinal function
WO2008132731A2 (en) * 2007-04-26 2008-11-06 Oramed Pharmaceuticals, Inc Methods and compositions for rectal administration of insulin
WO2008132732A2 (en) 2007-04-26 2008-11-06 Oramed Pharmaceuticals Inc Methods and compositions for rectal administration of proteins
EP2343982B1 (en) 2008-09-17 2017-03-22 Chiasma Inc. Pharmaceutical compositions and related methods of delivery

Also Published As

Publication number Publication date
PL3538132T3 (pl) 2021-06-28
CA3041390A1 (en) 2018-05-17
US11400137B2 (en) 2022-08-02
ES2850650T3 (es) 2021-08-31
DK3538132T3 (da) 2021-04-06
PT3538132T (pt) 2021-02-05
EP3538132B1 (en) 2020-12-30
EP3538132A1 (en) 2019-09-18
US20210038696A1 (en) 2021-02-11
WO2018087298A1 (en) 2018-05-17

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