EA201890346A1 - Ингибитор pdf4 для лечения диабетической нефропатии - Google Patents
Ингибитор pdf4 для лечения диабетической нефропатииInfo
- Publication number
- EA201890346A1 EA201890346A1 EA201890346A EA201890346A EA201890346A1 EA 201890346 A1 EA201890346 A1 EA 201890346A1 EA 201890346 A EA201890346 A EA 201890346A EA 201890346 A EA201890346 A EA 201890346A EA 201890346 A1 EA201890346 A1 EA 201890346A1
- Authority
- EA
- Eurasian Patent Office
- Prior art keywords
- inhibitor
- treatment
- pdf4
- diabetic
- phosphodiesterase
- Prior art date
Links
- 206010012601 diabetes mellitus Diseases 0.000 title 1
- 239000003112 inhibitor Substances 0.000 title 1
- 229940123932 Phosphodiesterase 4 inhibitor Drugs 0.000 abstract 3
- 239000002587 phosphodiesterase IV inhibitor Substances 0.000 abstract 3
- 239000005541 ACE inhibitor Substances 0.000 abstract 1
- 101710129690 Angiotensin-converting enzyme inhibitor Proteins 0.000 abstract 1
- 101710086378 Bradykinin-potentiating and C-type natriuretic peptides Proteins 0.000 abstract 1
- 208000007342 Diabetic Nephropathies Diseases 0.000 abstract 1
- 239000002333 angiotensin II receptor antagonist Substances 0.000 abstract 1
- 229940126317 angiotensin II receptor antagonist Drugs 0.000 abstract 1
- 229940044094 angiotensin-converting-enzyme inhibitor Drugs 0.000 abstract 1
- 208000033679 diabetic kidney disease Diseases 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A61K31/473—Quinolines; Isoquinolines ortho- or peri-condensed with carbocyclic ring systems, e.g. acridines, phenanthridines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/4164—1,3-Diazoles
- A61K31/4178—1,3-Diazoles not condensed 1,3-diazoles and containing further heterocyclic rings, e.g. pilocarpine, nitrofurantoin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/4164—1,3-Diazoles
- A61K31/4184—1,3-Diazoles condensed with carbocyclic rings, e.g. benzimidazoles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/4245—Oxadiazoles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/12—Drugs for disorders of the urinary system of the kidneys
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Epidemiology (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Urology & Nephrology (AREA)
- Nutrition Science (AREA)
- Physiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201562198213P | 2015-07-29 | 2015-07-29 | |
| PCT/EP2016/067968 WO2017017165A1 (en) | 2015-07-29 | 2016-07-28 | Pde4 inhibitor for the treatment of diabetic nephropathy |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| EA201890346A1 true EA201890346A1 (ru) | 2018-08-31 |
Family
ID=56551407
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| EA201890346A EA201890346A1 (ru) | 2015-07-29 | 2016-07-28 | Ингибитор pdf4 для лечения диабетической нефропатии |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US20200179369A1 (https=) |
| EP (1) | EP3328381A1 (https=) |
| JP (1) | JP2018521077A (https=) |
| CN (1) | CN108135886A (https=) |
| BR (1) | BR112018001116A2 (https=) |
| CA (1) | CA2992796A1 (https=) |
| EA (1) | EA201890346A1 (https=) |
| MA (1) | MA42519A (https=) |
| WO (1) | WO2017017165A1 (https=) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2018037109A1 (en) * | 2016-08-26 | 2018-03-01 | Takeda Gmbh | Treatment of nonalcoholic fatty liver disease |
| CN116637115A (zh) * | 2017-05-27 | 2023-08-25 | 广州喜鹊医药有限公司 | 川芎嗪硝酮衍生物组合物在预防和治疗糖尿病并发症疾病中的应用 |
| CN114053281B (zh) * | 2020-08-10 | 2025-05-27 | 成都文鼎科技发展有限公司 | 治疗慢性肾病的方法和药物组合物 |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2005508358A (ja) * | 2001-10-25 | 2005-03-31 | デポメド・インコーポレイテッド | 胃滞留型ロサルタン投与量を用いる治療方法 |
| US7157584B2 (en) * | 2004-02-25 | 2007-01-02 | Takeda Pharmaceutical Company Limited | Benzimidazole derivative and use thereof |
| PL2589599T4 (pl) * | 2004-03-03 | 2015-06-30 | Takeda Gmbh | Nowe hydroksy-6-heteroarylofenantrydyny i ich zastosowanie jako inhibitorów PDE4 |
| GB0504103D0 (en) * | 2005-02-28 | 2005-04-06 | Syngenta Ltd | Novel method |
-
2016
- 2016-07-28 JP JP2018503204A patent/JP2018521077A/ja active Pending
- 2016-07-28 CN CN201680056550.2A patent/CN108135886A/zh active Pending
- 2016-07-28 WO PCT/EP2016/067968 patent/WO2017017165A1/en not_active Ceased
- 2016-07-28 CA CA2992796A patent/CA2992796A1/en not_active Abandoned
- 2016-07-28 US US15/746,560 patent/US20200179369A1/en not_active Abandoned
- 2016-07-28 BR BR112018001116-9A patent/BR112018001116A2/pt not_active Application Discontinuation
- 2016-07-28 EP EP16744758.0A patent/EP3328381A1/en not_active Withdrawn
- 2016-07-28 MA MA042519A patent/MA42519A/fr unknown
- 2016-07-28 EA EA201890346A patent/EA201890346A1/ru unknown
Also Published As
| Publication number | Publication date |
|---|---|
| JP2018521077A (ja) | 2018-08-02 |
| CN108135886A (zh) | 2018-06-08 |
| EP3328381A1 (en) | 2018-06-06 |
| US20200179369A1 (en) | 2020-06-11 |
| MA42519A (fr) | 2018-06-06 |
| CA2992796A1 (en) | 2017-02-02 |
| BR112018001116A2 (pt) | 2018-09-11 |
| WO2017017165A1 (en) | 2017-02-02 |
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