EA201692284A1 - NIACINAMIDE FOR STIMULATING THE PRODUCTION OF ANTIMICROBIAL PEPTIDES - Google Patents

NIACINAMIDE FOR STIMULATING THE PRODUCTION OF ANTIMICROBIAL PEPTIDES

Info

Publication number
EA201692284A1
EA201692284A1 EA201692284A EA201692284A EA201692284A1 EA 201692284 A1 EA201692284 A1 EA 201692284A1 EA 201692284 A EA201692284 A EA 201692284A EA 201692284 A EA201692284 A EA 201692284A EA 201692284 A1 EA201692284 A1 EA 201692284A1
Authority
EA
Eurasian Patent Office
Prior art keywords
niacinamide
production
antimicrobial peptides
stimulating
skin
Prior art date
Application number
EA201692284A
Other languages
Russian (ru)
Other versions
EA031758B1 (en
Inventor
Амитабха Маджумдар
Мрутхунджая Свами Матхапати
Бхарат Паланисами
Кумар Рамиа Сампатха
Джоти Кумар Тивари
Original Assignee
Юнилевер Н.В.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Юнилевер Н.В. filed Critical Юнилевер Н.В.
Publication of EA201692284A1 publication Critical patent/EA201692284A1/en
Publication of EA031758B1 publication Critical patent/EA031758B1/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/455—Nicotinic acids, e.g. niacin; Derivatives thereof, e.g. esters, amides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/67—Vitamins
    • A61K8/673—Vitamin B group
    • A61K8/675—Vitamin B3 or vitamin B3 active, e.g. nicotinamide, nicotinic acid, nicotinyl aldehyde
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0014—Skin, i.e. galenical aspects of topical compositions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q11/00—Preparations for care of the teeth, of the oral cavity or of dentures; Dentifrices, e.g. toothpastes; Mouth rinses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q17/00—Barrier preparations; Preparations brought into direct contact with the skin for affording protection against external influences, e.g. sunlight, X-rays or other harmful rays, corrosive materials, bacteria or insect stings
    • A61Q17/005—Antimicrobial preparations
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q5/00—Preparations for care of the hair

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Epidemiology (AREA)
  • Dermatology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Communicable Diseases (AREA)
  • Birds (AREA)
  • Oncology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Cosmetics (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)

Abstract

Изобретение относится к новому применению ниацинамида для стимуляции продуцирования AMP (антимикробных пептидов) в коже. Изобретение может применяться для улучшения иммунитета кожи, волосистой части кожи головы и полости рта в отношении микроорганизмов.The invention relates to the use of niacinamide to stimulate the production of AMP (antimicrobial peptides) in the skin. The invention can be used to improve the immunity of the skin, scalp and mouth against microorganisms.

EA201692284A 2014-05-12 2014-05-12 Niacinamide for inducing generation of antimicrobial peptides EA031758B1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/EP2014/059590 WO2015172801A1 (en) 2014-05-12 2014-05-12 Niacinamide for inducing generation of antimicrobial peptides

Publications (2)

Publication Number Publication Date
EA201692284A1 true EA201692284A1 (en) 2017-03-31
EA031758B1 EA031758B1 (en) 2019-02-28

Family

ID=50771476

Family Applications (1)

Application Number Title Priority Date Filing Date
EA201692284A EA031758B1 (en) 2014-05-12 2014-05-12 Niacinamide for inducing generation of antimicrobial peptides

Country Status (8)

Country Link
JP (1) JP6446065B2 (en)
CN (2) CN106413680A (en)
BR (1) BR112016024400A2 (en)
EA (1) EA031758B1 (en)
MX (1) MX2016014760A (en)
PH (1) PH12016502047A1 (en)
WO (1) WO2015172801A1 (en)
ZA (1) ZA201607105B (en)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20180030721A (en) 2015-08-10 2018-03-23 마리 케이 인코포레이티드 Topical compositions
CN108135824B (en) 2015-10-05 2021-09-17 联合利华知识产权控股有限公司 Composition comprising nicotinamide and pyridine 2-carboxamide
EA036976B1 (en) * 2016-05-10 2021-01-21 Юнилевер Н.В. Topical composition
CN109152732A (en) 2016-05-26 2019-01-04 荷兰联合利华有限公司 Antimicrobial compositions for local use
EP3426276B1 (en) * 2017-05-24 2024-01-24 Follea International Synephrine compositions
EP3703690A1 (en) 2017-10-30 2020-09-09 Unilever N.V. Use of niacinamide for microbiome balancing
EP3727315B1 (en) 2017-12-18 2021-10-13 Unilever Global IP Limited A topical composition comprising n-cyclopropyl nicotinamide
EP3727316B1 (en) * 2017-12-18 2021-10-13 Unilever Global IP Limited A topical composition based on niacinamide derivative
EA202092166A1 (en) 2018-03-13 2020-12-25 Юнилевер Н.В. SANITIZER COMPOSITION
WO2024041911A1 (en) * 2022-08-25 2024-02-29 Unilever Ip Holdings B.V. A nasal drop composition and device thereof
WO2024042554A1 (en) * 2022-08-25 2024-02-29 Istituto Fondazione Di Oncologia Molecolare Ets A pharmaceutical composition for treatment of viral infections

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AUPN892496A0 (en) * 1996-03-25 1996-04-18 Technical Consultancy Services Pty Limited Acne treatment
US7026308B1 (en) * 1999-06-25 2006-04-11 The Procter & Gamble Company Topical anti-microbial compositions
RU2401100C2 (en) * 2004-10-15 2010-10-10 Байер Конзюмер Кер АГ Acid and buffer skin care compositions containing nicotinamide and absorbing agent
CN101019865A (en) * 2007-01-23 2007-08-22 中国医学科学院皮肤病医院 Compound nicotinamide medicine for antiphlogosis, wet storage and eliminating spot
WO2011133692A1 (en) * 2010-04-20 2011-10-27 Cedars-Sinai Medical Center Boosting immune defense by upregulating ccaat/enhancer binding protein epsilon
WO2012049677A2 (en) * 2010-10-10 2012-04-19 Dermipsor Ltd. Compositions for treating psoriasis of the scalp
FR2973699B1 (en) * 2011-04-05 2013-04-26 Oreal NOVEL ACTIVE INGREDIENT TO STIMULATE THE PRODUCTION OF ANTI-MICROBIAL PEPTIDES IN SCALP, USEFUL IN PREVENTING AND / OR TREATING SCALPLET FILM CONDITIONS
US8293790B2 (en) * 2011-10-19 2012-10-23 Dignity Sciences Limited Pharmaceutical compositions comprising DGLA and benzoyl peroxide and methods of use thereof
DE102012002592A1 (en) * 2012-02-13 2013-08-14 Dr. Kurt Wolff Gmbh & Co. Kg Use of an agent for stimulating the gene expression of antimicrobial peptides (AMP)
JP6855165B2 (en) * 2012-06-15 2021-04-07 コナリス リサーチ インスティチュート アーゲー A pharmaceutical composition containing nicotinic acid and / or nicotinamide and / or tryptophan to have a positive effect on the intestinal microflora.
EP3120850B1 (en) * 2012-12-14 2018-11-07 Unilever N.V. Niacinamide for inducing generation of antimicrobial peptides

Also Published As

Publication number Publication date
PH12016502047A1 (en) 2017-01-09
JP2017515829A (en) 2017-06-15
CN113908074A (en) 2022-01-11
CN106413680A (en) 2017-02-15
MX2016014760A (en) 2017-03-06
BR112016024400A2 (en) 2017-08-15
EA031758B1 (en) 2019-02-28
WO2015172801A1 (en) 2015-11-19
JP6446065B2 (en) 2018-12-26
ZA201607105B (en) 2018-05-30

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Legal Events

Date Code Title Description
MM4A Lapse of a eurasian patent due to non-payment of renewal fees within the time limit in the following designated state(s)

Designated state(s): AM AZ BY KZ KG TJ TM

PC4A Registration of transfer of a eurasian patent by assignment