PH12016502047A1 - Niacinamide for including generation of antimicrobial peptides - Google Patents

Niacinamide for including generation of antimicrobial peptides

Info

Publication number
PH12016502047A1
PH12016502047A1 PH12016502047A PH12016502047A PH12016502047A1 PH 12016502047 A1 PH12016502047 A1 PH 12016502047A1 PH 12016502047 A PH12016502047 A PH 12016502047A PH 12016502047 A PH12016502047 A PH 12016502047A PH 12016502047 A1 PH12016502047 A1 PH 12016502047A1
Authority
PH
Philippines
Prior art keywords
niacinamide
antimicrobial peptides
including generation
skin
generation
Prior art date
Application number
PH12016502047A
Inventor
Majumdar Amitabha
Mathapathi Mruthyunjaya Swamy
Palanisamy Bharath
Sampath Kumar Ramya
Tiwari Jyoti Kumar
Original Assignee
Unilever Nv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Unilever Nv filed Critical Unilever Nv
Publication of PH12016502047A1 publication Critical patent/PH12016502047A1/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/455—Nicotinic acids, e.g. niacin; Derivatives thereof, e.g. esters, amides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/67—Vitamins
    • A61K8/673—Vitamin B group
    • A61K8/675—Vitamin B3 or vitamin B3 active, e.g. nicotinamide, nicotinic acid, nicotinyl aldehyde
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0014—Skin, i.e. galenical aspects of topical compositions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q11/00—Preparations for care of the teeth, of the oral cavity or of dentures; Dentifrices, e.g. toothpastes; Mouth rinses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q17/00—Barrier preparations; Preparations brought into direct contact with the skin for affording protection against external influences, e.g. sunlight, X-rays or other harmful rays, corrosive materials, bacteria or insect stings
    • A61Q17/005—Antimicrobial preparations
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q5/00—Preparations for care of the hair

Abstract

The invention relates to new use of niacinamide for triggering generation of AMPs (antimicrobial peptides) on skin. This has application in improving the immunity of skin, scalp and oral cavity against attack by microorganisms.
PH12016502047A 2014-05-12 2016-10-14 Niacinamide for including generation of antimicrobial peptides PH12016502047A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/EP2014/059590 WO2015172801A1 (en) 2014-05-12 2014-05-12 Niacinamide for inducing generation of antimicrobial peptides

Publications (1)

Publication Number Publication Date
PH12016502047A1 true PH12016502047A1 (en) 2017-01-09

Family

ID=50771476

Family Applications (1)

Application Number Title Priority Date Filing Date
PH12016502047A PH12016502047A1 (en) 2014-05-12 2016-10-14 Niacinamide for including generation of antimicrobial peptides

Country Status (8)

Country Link
JP (1) JP6446065B2 (en)
CN (2) CN113908074A (en)
BR (1) BR112016024400A2 (en)
EA (1) EA031758B1 (en)
MX (1) MX2016014760A (en)
PH (1) PH12016502047A1 (en)
WO (1) WO2015172801A1 (en)
ZA (1) ZA201607105B (en)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2017027603A1 (en) 2015-08-10 2017-02-16 Mary Kay Inc. Topical compositions
JP6880011B2 (en) 2015-10-05 2021-06-02 ユニリーバー・ナームローゼ・ベンノートシヤープ Skin whitening composition
EA036976B1 (en) * 2016-05-10 2021-01-21 Юнилевер Н.В. Topical composition
EP3463288A1 (en) 2016-05-26 2019-04-10 Unilever N.V. Antimicrobial compositions for topical use
EP3426276B1 (en) 2017-05-24 2024-01-24 Follea International Synephrine compositions
CN111295190A (en) * 2017-10-30 2020-06-16 荷兰联合利华有限公司 Use of nicotinamide for microbiome balance
BR112020011640A2 (en) 2017-12-18 2020-11-17 Unilever Nv topical composition, method of disinfecting surfaces and uses of the composition
CN111683649A (en) * 2017-12-18 2020-09-18 荷兰联合利华有限公司 Topical compositions based on nicotinamide derivatives
EP3764975B1 (en) 2018-03-13 2021-10-13 Unilever Global IP Limited A sanitizer composition
WO2024041911A1 (en) * 2022-08-25 2024-02-29 Unilever Ip Holdings B.V. A nasal drop composition and device thereof
WO2024042554A1 (en) * 2022-08-25 2024-02-29 Istituto Fondazione Di Oncologia Molecolare Ets A pharmaceutical composition for treatment of viral infections

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AUPN892496A0 (en) * 1996-03-25 1996-04-18 Technical Consultancy Services Pty Limited Acne treatment
US7026308B1 (en) * 1999-06-25 2006-04-11 The Procter & Gamble Company Topical anti-microbial compositions
RU2401100C2 (en) * 2004-10-15 2010-10-10 Байер Конзюмер Кер АГ Acid and buffer skin care compositions containing nicotinamide and absorbing agent
CN101019865A (en) * 2007-01-23 2007-08-22 中国医学科学院皮肤病医院 Compound nicotinamide medicine for antiphlogosis, wet storage and eliminating spot
WO2011133692A1 (en) * 2010-04-20 2011-10-27 Cedars-Sinai Medical Center Boosting immune defense by upregulating ccaat/enhancer binding protein epsilon
CA2814135A1 (en) * 2010-10-10 2012-04-19 Dermipsor Ltd. Compositions for treating psoriasis of the scalp
FR2973699B1 (en) * 2011-04-05 2013-04-26 Oreal NOVEL ACTIVE INGREDIENT TO STIMULATE THE PRODUCTION OF ANTI-MICROBIAL PEPTIDES IN SCALP, USEFUL IN PREVENTING AND / OR TREATING SCALPLET FILM CONDITIONS
US8293790B2 (en) * 2011-10-19 2012-10-23 Dignity Sciences Limited Pharmaceutical compositions comprising DGLA and benzoyl peroxide and methods of use thereof
DE102012002592A1 (en) * 2012-02-13 2013-08-14 Dr. Kurt Wolff Gmbh & Co. Kg Use of an agent for stimulating the gene expression of antimicrobial peptides (AMP)
RS61288B1 (en) * 2012-06-15 2021-02-26 Conaris Res Institute Ag A pharmaceutical composition containing nicotinic acid and/or nicotinamide and/or tryptophan for positively influencing the intestinal microbiota
ES2741656T3 (en) * 2012-12-14 2020-02-11 Unilever Nv Niacinamide to induce the generation of antimicrobial peptides

Also Published As

Publication number Publication date
CN113908074A (en) 2022-01-11
JP2017515829A (en) 2017-06-15
MX2016014760A (en) 2017-03-06
EA201692284A1 (en) 2017-03-31
JP6446065B2 (en) 2018-12-26
EA031758B1 (en) 2019-02-28
WO2015172801A1 (en) 2015-11-19
CN106413680A (en) 2017-02-15
ZA201607105B (en) 2018-05-30
BR112016024400A2 (en) 2017-08-15

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