EA201690465A1 - Способ оценки эффектов композиции, содержащей микроорганизмы, на кишечную микробиоту - Google Patents

Способ оценки эффектов композиции, содержащей микроорганизмы, на кишечную микробиоту

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Publication number
EA201690465A1
EA201690465A1 EA201690465A EA201690465A EA201690465A1 EA 201690465 A1 EA201690465 A1 EA 201690465A1 EA 201690465 A EA201690465 A EA 201690465A EA 201690465 A EA201690465 A EA 201690465A EA 201690465 A1 EA201690465 A1 EA 201690465A1
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EA
Eurasian Patent Office
Prior art keywords
microbiot
intestinal
containing microorganisms
composition effects
effects containing
Prior art date
Application number
EA201690465A
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English (en)
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EA034795B1 (ru
Inventor
Андреа Биффи
Руджеро Росси
Вальтер Фьоре
Симоне Доменико Гульельметти
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Софар С.П.А.
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Application filed by Софар С.П.А. filed Critical Софар С.П.А.
Publication of EA201690465A1 publication Critical patent/EA201690465A1/ru
Publication of EA034795B1 publication Critical patent/EA034795B1/ru

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/66—Microorganisms or materials therefrom
    • A61K35/74—Bacteria
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A23L33/135—Bacteria or derivatives thereof, e.g. probiotics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/66—Microorganisms or materials therefrom
    • A61K35/74—Bacteria
    • A61K35/741—Probiotics
    • A61K35/744—Lactic acid bacteria, e.g. enterococci, pediococci, lactococci, streptococci or leuconostocs
    • A61K35/747—Lactobacilli, e.g. L. acidophilus or L. brevis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20—Bacteria; Culture media therefor
    • C12N1/205—Bacterial isolates
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/02—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving viable microorganisms
    • C12Q1/04—Determining presence or kind of microorganism; Use of selective media for testing antibiotics or bacteriocides; Compositions containing a chemical indicator therefor
    • C12Q1/10—Enterobacteria
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6888—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for detection or identification of organisms
    • C12Q1/689—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for detection or identification of organisms for bacteria
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    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/106—Pharmacogenomics, i.e. genetic variability in individual responses to drugs and drug metabolism
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    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/136—Screening for pharmacological compounds
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    • C12Q2600/00—Oligonucleotides characterized by their use
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    • C—CHEMISTRY; METALLURGY
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    • C12R—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
    • C12R2001/00—Microorganisms ; Processes using microorganisms
    • C12R2001/01—Bacteria or Actinomycetales ; using bacteria or Actinomycetales
    • C12R2001/225—Lactobacillus

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  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Microbiology (AREA)
  • General Health & Medical Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Molecular Biology (AREA)
  • Mycology (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Immunology (AREA)
  • Epidemiology (AREA)
  • Nutrition Science (AREA)
  • Polymers & Plastics (AREA)
  • Food Science & Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Toxicology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Virology (AREA)
  • Biomedical Technology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)

Abstract

Настоящее изобретение относится к способу определения пробиотической/парапробиотической активности композиции, содержащей микроорганизмы, в частности бактерии, основанному на оценке, посредством метагеномного анализа, качественных и/или количественных изменений в фекальной микробиоте после приема композиции. Кроме того, настоящее изобретение относится к набору для осуществления указанного способа.
EA201690465A 2013-09-06 2014-09-05 Способ определения изменений фекальной микробиоты индивида после приема композиции, содержащей микроорганизмы EA034795B1 (ru)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IT001473A ITMI20131473A1 (it) 2013-09-06 2013-09-06 Metodo per valutare gli effetti di una composizione comprendente microrganismi sul microbiota intestinale
PCT/IB2014/064284 WO2015033304A1 (en) 2013-09-06 2014-09-05 Method for evaluating the effects of a composition comprising microorganisms on intestinal microbiota

Publications (2)

Publication Number Publication Date
EA201690465A1 true EA201690465A1 (ru) 2016-08-31
EA034795B1 EA034795B1 (ru) 2020-03-23

Family

ID=49354801

Family Applications (2)

Application Number Title Priority Date Filing Date
EA201690465A EA034795B1 (ru) 2013-09-06 2014-09-05 Способ определения изменений фекальной микробиоты индивида после приема композиции, содержащей микроорганизмы
EA202090097A EA202090097A1 (ru) 2013-09-06 2014-09-05 Способ оценки эффектов композиции, содержащей микроорганизмы, на кишечную микробиоту

Family Applications After (1)

Application Number Title Priority Date Filing Date
EA202090097A EA202090097A1 (ru) 2013-09-06 2014-09-05 Способ оценки эффектов композиции, содержащей микроорганизмы, на кишечную микробиоту

Country Status (13)

Country Link
US (1) US20160348155A1 (ru)
EP (1) EP3047032A1 (ru)
JP (1) JP6701078B2 (ru)
CN (1) CN105518150A (ru)
BR (1) BR112016005064A2 (ru)
CA (1) CA2923390A1 (ru)
EA (2) EA034795B1 (ru)
HK (1) HK1223982A1 (ru)
IL (1) IL244391B (ru)
IT (1) ITMI20131473A1 (ru)
MX (2) MX2016002766A (ru)
SG (1) SG11201601664VA (ru)
WO (1) WO2015033304A1 (ru)

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Publication number Priority date Publication date Assignee Title
ITMI20131467A1 (it) 2013-09-06 2015-03-07 Sofar Spa Uso di una composizione comprendente microrganismi per aumentare la produzione intestinale di acido butirrico, di acido folico o di niacina e/o per diminuire la produzione intestinale di acido succinico
MA39710A (fr) 2014-04-23 2015-10-29 Sofar Spa Composition topique destinée à être utilisée dans le traitement d'une maladie inflammatoire de l'intestin
KR20180073562A (ko) 2015-10-29 2018-07-02 가부시키가이샤 야쿠르트 혼샤 에쿠올 산생능의 측정 방법
MA45327A (fr) 2016-05-13 2019-03-20 Sofar Spa Utilisation de probiotiques pour améliorer l'absorption des protéines
MA45288A (fr) 2016-06-08 2019-04-17 Sofar Spa Nouvelle utilisation médicale de probiotiques
CN106318890A (zh) * 2016-10-21 2017-01-11 山东省农业科学院畜牧兽医研究所 一株分离自spf鸡嗉囊的产植酸酶卷曲乳杆菌菌株及其应用
IT201600122724A1 (it) 2016-12-02 2018-06-02 Sofar Spa Exopolysaccharides and uses thereof
IT201600127498A1 (it) 2016-12-16 2018-06-16 Sofar Spa Probiotici per uso nella diverticolosi e malattia diverticolare
IT201700101704A1 (it) * 2017-09-12 2019-03-12 Sofar Spa Nuovo uso per trattamento delle infezioni da clostridium difficile
MX2020007619A (es) * 2018-01-17 2020-09-28 Consorcio Centro De Investig Biomedica En Red M P Intervenciones dirigidas, encaminadas a reducir los niveles de succinato circulante en un sujeto, y kits y metodo para determinar la eficacia de dichas intervenciones.
EP3749329A1 (en) 2018-02-09 2020-12-16 N.V. Nutricia Fermented formula with non-digestible oligosaccharides
CA3095745A1 (en) * 2018-04-02 2019-10-10 Sun Genomics, Inc. Universal method for extracting nucleic acid molecules from a diverse population of one or more types of microbes in a sample
CN110029155A (zh) * 2019-05-27 2019-07-19 天益健康科学研究院（镇江）有限公司 一种基于荧光定量pcr组合式肠道细菌检测方法
US11751597B2 (en) 2019-11-05 2023-09-12 Alfasigma S.P.A. Compositions comprising bacterial strains for use in increasing the bioavailability of amino acids derived from proteins, and related food product methods and systems
CN112980712A (zh) * 2019-12-14 2021-06-18 山东大学 一种调节高原人群情绪及肠道菌群稳定的微生物组合物及其应用
CN116287163A (zh) * 2023-02-17 2023-06-23 浙江大学 一种评估肠道菌群对菊粉的动态响应方法

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AU2002951270A0 (en) * 2002-09-06 2002-09-19 Vri Biomedical Ltd Probiotic Bacterium and Methods of Use
WO2005001109A2 (en) * 2003-05-06 2005-01-06 Government Of The United States Of America As Represented By The Sercretary Of The Department Of Health And Human Services National Institutes Of Health Methods and compositions to detect microbes in fecal samples
CA2557543A1 (en) * 2004-02-27 2005-09-09 Stichting Laboratorium Voor Infectieziekten Method for detecting a microorganism in a fecal specimen
CA2587670A1 (en) * 2004-11-01 2006-05-11 George Mason University Compositions and methods for diagnosing colon disorders
FI20051319L (fi) * 2005-12-22 2007-06-23 Cyflo Oy Menetelmä eläimen ja/tai ihmisen ravitsemuksen ja hyvinvoinnin ja eläinten tuottavuuden seuraamiseksi ja kehittämiseksi
CN1840206A (zh) * 2006-01-19 2006-10-04 上海交通大学 人源菌群仔猪模型的构建及仔猪肠道中菌群分子检测方法
JP4590573B2 (ja) * 2006-02-21 2010-12-01 国立大学法人富山大学 感染症起因菌の迅速同定方法
CN101240315A (zh) * 2008-02-21 2008-08-13 上海交通大学 检测药物防癌效果的非损伤性分子方法
JP2010161944A (ja) * 2009-01-13 2010-07-29 Syngen Biotech Co Ltd 新型カゼイ菌の亜種（ｓｇ９６）及びこれを含有する菌抑制組成物及びその用途

Also Published As

Publication number Publication date
JP6701078B2 (ja) 2020-05-27
BR112016005064A2 (pt) 2017-11-21
CA2923390A1 (en) 2015-03-12
EA034795B1 (ru) 2020-03-23
MX2016002766A (es) 2016-08-03
US20160348155A1 (en) 2016-12-01
JP2016528926A (ja) 2016-09-23
ITMI20131473A1 (it) 2015-03-07
SG11201601664VA (en) 2016-04-28
MX2022013625A (es) 2022-11-16
CN105518150A (zh) 2016-04-20
WO2015033304A1 (en) 2015-03-12
HK1223982A1 (zh) 2017-08-11
EP3047032A1 (en) 2016-07-27
EA202090097A1 (ru) 2020-04-07
IL244391A0 (en) 2016-04-21
IL244391B (en) 2021-02-28

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