EA201690042A1 - Композиции и способы для применения в онкологии - Google Patents
Композиции и способы для применения в онкологииInfo
- Publication number
- EA201690042A1 EA201690042A1 EA201690042A EA201690042A EA201690042A1 EA 201690042 A1 EA201690042 A1 EA 201690042A1 EA 201690042 A EA201690042 A EA 201690042A EA 201690042 A EA201690042 A EA 201690042A EA 201690042 A1 EA201690042 A1 EA 201690042A1
- Authority
- EA
- Eurasian Patent Office
- Prior art keywords
- nanoparticles
- aggregates
- nanoparticle
- oncology
- compositions
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
- A61K9/0024—Solid, semi-solid or solidifying implants, which are implanted or injected in body tissue
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K49/00—Preparations for testing in vivo
- A61K49/04—X-ray contrast preparations
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K49/00—Preparations for testing in vivo
- A61K49/04—X-ray contrast preparations
- A61K49/0409—Physical forms of mixtures of two different X-ray contrast-enhancing agents, containing at least one X-ray contrast-enhancing agent which is not a halogenated organic compound
- A61K49/0414—Particles, beads, capsules or spheres
- A61K49/0423—Nanoparticles, nanobeads, nanospheres, nanocapsules, i.e. having a size or diameter smaller than 1 micrometer
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K49/00—Preparations for testing in vivo
- A61K49/04—X-ray contrast preparations
- A61K49/0433—X-ray contrast preparations containing an organic halogenated X-ray contrast-enhancing agent
- A61K49/0447—Physical forms of mixtures of two different X-ray contrast-enhancing agents, containing at least one X-ray contrast-enhancing agent which is a halogenated organic compound
- A61K49/0457—Semi-solid forms, ointments, gels, hydrogels
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/06—Ointments; Bases therefor; Other semi-solid forms, e.g. creams, sticks, gels
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Nanotechnology (AREA)
- Neurosurgery (AREA)
- Dermatology (AREA)
- Biomedical Technology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Medicinal Preparation (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Radiation-Therapy Devices (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
Настоящее изобретение относится к композициям и способам для применения в медицинской диагностике и для наблюдения за состоянием пациента, как правило, в контексте терапии, в частности в контексте онкологии для оптимизации локального облучения ложа опухоли. Более конкретно, изобретение относится к биологически совместимому гелю, который содержит наночастицы и/или агрегаты наночастиц, где i) плотность каждой из наночастиц и каждого из агрегатов наночастиц составляет по меньшей мере 7 г/см, наночастица или агрегат наночастиц, которые содержат неорганический материал, включающий в себя по меньшей мере один металлический элемент с атомным номером Z по меньшей мере 25, более предпочтительно по меньшей мере 40, каждая из указанных наночастиц и каждый из указанных агрегатов наночастиц покрыты биологически совместимым покрытием; ii) концентрация наночастиц и/или агрегатов наночастиц составляет по меньшей мере приблизительно 1% (мас./мас.) и iii) эффективная вязкость при 2 сгеля, содержащего наночастицы и/или агрегаты наночастиц, составляет приблизительно от 0,1 до приблизительно 1000 Па∙с при измерении в интервале от 20 до 37°С.
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201361837406P | 2013-06-20 | 2013-06-20 | |
| EP13305830 | 2013-06-20 | ||
| PCT/EP2014/062976 WO2014202738A1 (en) | 2013-06-20 | 2014-06-19 | Compositions and methods for use in oncology |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| EA201690042A1 true EA201690042A1 (ru) | 2016-06-30 |
| EA033792B1 EA033792B1 (ru) | 2019-11-26 |
Family
ID=48741003
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| EA201690042A EA033792B1 (ru) | 2013-06-20 | 2014-06-19 | Способ лечения рака с помощью биологически совместимого геля, содержащего наночастицы и/или агрегаты наночастиц |
Country Status (18)
| Country | Link |
|---|---|
| US (1) | US20160136304A1 (ru) |
| EP (1) | EP3010552B1 (ru) |
| JP (1) | JP6484229B2 (ru) |
| KR (1) | KR102217217B1 (ru) |
| CN (1) | CN105431174B (ru) |
| AU (1) | AU2014283232B2 (ru) |
| BR (1) | BR112015031984A2 (ru) |
| CA (1) | CA2915145C (ru) |
| CY (1) | CY1121770T1 (ru) |
| EA (1) | EA033792B1 (ru) |
| HK (1) | HK1222561A1 (ru) |
| MA (1) | MA38710A1 (ru) |
| MX (1) | MX2015017780A (ru) |
| PL (1) | PL3010552T3 (ru) |
| RS (1) | RS58800B1 (ru) |
| SG (1) | SG11201510468TA (ru) |
| SI (1) | SI3010552T1 (ru) |
| WO (1) | WO2014202738A1 (ru) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SG11201403096VA (en) | 2011-12-16 | 2014-07-30 | Nanobiotix | Nanoparticles comprising metallic and hafnium oxide materials, preparation and uses thereof |
| MA38709A1 (fr) * | 2013-06-20 | 2018-05-31 | Nanobiotix | Compositions et procédés pour une utilisation en diagnostic médical |
| AR104806A1 (es) | 2015-05-28 | 2017-08-16 | Nanobiotix | Nanopartículas para uso como vacuna terapéutica |
| US9607952B1 (en) * | 2015-10-30 | 2017-03-28 | International Business Machines Corporation | High-z oxide nanoparticles embedded in semiconductor package |
| CN113842395B (zh) * | 2021-10-15 | 2022-12-23 | 中国科学院高能物理研究所 | 钽纳米复合物及包含该钽纳米复合物的淋巴示踪剂、放疗增敏剂 |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5370901A (en) * | 1991-02-15 | 1994-12-06 | Bracco International B.V. | Compositions for increasing the image contrast in diagnostic investigations of the digestive tract of patients |
| FR2869803B1 (fr) * | 2004-05-10 | 2006-07-28 | Nanobiotix Sarl | Particules activables, preparation et utilisations |
| WO2007052267A2 (en) * | 2005-11-01 | 2007-05-10 | Yissum Research Development Company Of The Hebrew University Of Jerusalem | Biodegradable composite for internal local radiotherapy |
| US8043005B2 (en) * | 2006-06-02 | 2011-10-25 | Hydrapak, Inc. | Reservoir closure system and method |
| JP5820815B2 (ja) * | 2009-12-15 | 2015-11-24 | インセプト・リミテッド・ライアビリティ・カンパニーＩｎｃｅｐｔ，Ｌｌｃ | インプラントおよび生体分解性基準マーカー |
-
2014
- 2014-06-19 SG SG11201510468TA patent/SG11201510468TA/en unknown
- 2014-06-19 EA EA201690042A patent/EA033792B1/ru not_active IP Right Cessation
- 2014-06-19 US US14/898,767 patent/US20160136304A1/en not_active Abandoned
- 2014-06-19 BR BR112015031984A patent/BR112015031984A2/pt not_active IP Right Cessation
- 2014-06-19 MX MX2015017780A patent/MX2015017780A/es active IP Right Grant
- 2014-06-19 KR KR1020167001665A patent/KR102217217B1/ko active IP Right Grant
- 2014-06-19 EP EP14731952.9A patent/EP3010552B1/en active Active
- 2014-06-19 RS RS20190657A patent/RS58800B1/sr unknown
- 2014-06-19 JP JP2016520500A patent/JP6484229B2/ja active Active
- 2014-06-19 MA MA38710A patent/MA38710A1/fr unknown
- 2014-06-19 SI SI201431195T patent/SI3010552T1/sl unknown
- 2014-06-19 CA CA2915145A patent/CA2915145C/en active Active
- 2014-06-19 AU AU2014283232A patent/AU2014283232B2/en not_active Ceased
- 2014-06-19 PL PL14731952T patent/PL3010552T3/pl unknown
- 2014-06-19 CN CN201480035294.XA patent/CN105431174B/zh active Active
- 2014-06-19 WO PCT/EP2014/062976 patent/WO2014202738A1/en active Application Filing
-
2016
- 2016-09-12 HK HK16110779.8A patent/HK1222561A1/zh unknown
-
2019
- 2019-05-22 CY CY20191100546T patent/CY1121770T1/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| CY1121770T1 (el) | 2020-07-31 |
| CN105431174B (zh) | 2019-06-07 |
| MA38710A1 (fr) | 2017-12-29 |
| HK1222561A1 (zh) | 2017-07-07 |
| EP3010552A1 (en) | 2016-04-27 |
| KR20160027011A (ko) | 2016-03-09 |
| RS58800B1 (sr) | 2019-07-31 |
| SI3010552T1 (sl) | 2019-08-30 |
| KR102217217B1 (ko) | 2021-02-18 |
| PL3010552T3 (pl) | 2019-09-30 |
| EA033792B1 (ru) | 2019-11-26 |
| BR112015031984A2 (pt) | 2017-07-25 |
| CA2915145A1 (en) | 2014-12-24 |
| AU2014283232A1 (en) | 2016-01-21 |
| CA2915145C (en) | 2021-06-08 |
| CN105431174A (zh) | 2016-03-23 |
| AU2014283232B2 (en) | 2019-03-28 |
| JP2016523244A (ja) | 2016-08-08 |
| US20160136304A1 (en) | 2016-05-19 |
| SG11201510468TA (en) | 2016-01-28 |
| EP3010552B1 (en) | 2019-04-17 |
| MX2015017780A (es) | 2016-07-06 |
| JP6484229B2 (ja) | 2019-03-13 |
| WO2014202738A1 (en) | 2014-12-24 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| MM4A | Lapse of a eurasian patent due to non-payment of renewal fees within the time limit in the following designated state(s) |
Designated state(s): AM AZ BY KZ KG TJ TM |