EA201591772A1 - Средство для профилактики и/или лечения опухолевых заболеваний - Google Patents

Средство для профилактики и/или лечения опухолевых заболеваний

Info

Publication number
EA201591772A1
EA201591772A1 EA201591772A EA201591772A EA201591772A1 EA 201591772 A1 EA201591772 A1 EA 201591772A1 EA 201591772 A EA201591772 A EA 201591772A EA 201591772 A EA201591772 A EA 201591772A EA 201591772 A1 EA201591772 A1 EA 201591772A1
Authority
EA
Eurasian Patent Office
Prior art keywords
prevention
treatment
tumor diseases
rhodanine
antiproliferative
Prior art date
Application number
EA201591772A
Other languages
English (en)
Other versions
EA026332B1 (ru
Inventor
Рахимджан Ахметджанович РОЗИЕВ
Анна Яковлевна ГОНЧАРОВА
Кенес Тагаевич ЕРИМБЕТОВ
Владимир Константинович ПОДГОРОДНИЧЕНКО
Виктор Владимирович ХОМИЧЕНОК
Наталья Евгеньевна НОВОЖИЛОВА
Original Assignee
Общество с ограниченной ответственностью "Тиацен"
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from RU2013111415/04A external-priority patent/RU2522449C1/ru
Priority claimed from RU2013111416/15A external-priority patent/RU2521390C1/ru
Application filed by Общество с ограниченной ответственностью "Тиацен" filed Critical Общество с ограниченной ответственностью "Тиацен"
Publication of EA201591772A1 publication Critical patent/EA201591772A1/ru
Publication of EA026332B1 publication Critical patent/EA026332B1/ru

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
    • A61K31/4436—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a heterocyclic ring having sulfur as a ring hetero atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/425—Thiazoles
    • A61K31/426—1,3-Thiazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
    • A61K31/4439—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. omeprazole
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/04—Antineoplastic agents specific for metastasis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D277/32—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D277/36—Sulfur atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Oncology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

Изобретение относится к новому средству, представляющему собой производные роданина, которое обладает профилактическим, антипролиферативным и антиметастатическим действием. Указанное средство может найти применение в медицине и фармакологии для профилактики и/или лечения опухолевых заболеваний различной локализации.
EA201591772A 2013-03-14 2014-03-12 Применение производных роданина для профилактики и/или лечения опухолевых заболеваний EA026332B1 (ru)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
RU2013111415/04A RU2522449C1 (ru) 2013-03-14 2013-03-14 Средство, обладающее антипролиферативным и антиметастатическим действием, для лечения опухолевых заболеваний
RU2013111416/15A RU2521390C1 (ru) 2013-03-14 2013-03-14 Производное роданина и средство для профилактики опухолевых заболеваний
PCT/IB2014/059659 WO2014141082A1 (ru) 2013-03-14 2014-03-12 Cредство для профилактики и/или лечения опухолевых заболеваний

Publications (2)

Publication Number Publication Date
EA201591772A1 true EA201591772A1 (ru) 2015-12-30
EA026332B1 EA026332B1 (ru) 2017-03-31

Family

ID=51535965

Family Applications (1)

Application Number Title Priority Date Filing Date
EA201591772A EA026332B1 (ru) 2013-03-14 2014-03-12 Применение производных роданина для профилактики и/или лечения опухолевых заболеваний

Country Status (4)

Country Link
US (1) US9949961B2 (ru)
EP (1) EP2974726A4 (ru)
EA (1) EA026332B1 (ru)
WO (1) WO2014141082A1 (ru)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN116196415B (zh) * 2022-12-07 2023-08-01 浙江省肿瘤医院 用于增敏pd-1抗体的混合制剂及其使用方法

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SU119529A1 (ru) * 1958-06-23 1958-11-30 С.Н. Баранов Способ получени роданина
US5725895B1 (en) 1995-09-15 2000-10-10 Hopkins J School Of Medicine Method of preparing food product from cruciferous seeds
CN100358867C (zh) * 2000-05-11 2008-01-02 科学研究高等机关 糖原合酶激酶gsk-3的杂环抑制剂
EP1802614A1 (en) 2004-10-14 2007-07-04 F. Hoffmann-Roche AG Quinazolinylmethylenethiazolinones as cdk1 inhibitors
KR100875870B1 (ko) * 2004-10-14 2008-12-26 에프. 호프만-라 로슈 아게 항암제로서의 신규 아자인돌 티아졸리논
SI2080516T1 (sl) * 2008-01-18 2011-09-30 Indena Spa Uporaba iztiocianatnih derivatov kot sredstev proti mielomu

Also Published As

Publication number Publication date
EP2974726A1 (en) 2016-01-20
EA026332B1 (ru) 2017-03-31
US20160038472A1 (en) 2016-02-11
WO2014141082A1 (ru) 2014-09-18
EP2974726A4 (en) 2017-01-04
US9949961B2 (en) 2018-04-24

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Legal Events

Date Code Title Description
MM4A Lapse of a eurasian patent due to non-payment of renewal fees within the time limit in the following designated state(s)

Designated state(s): AM AZ KZ KG TJ TM RU

PC4A Registration of transfer of a eurasian patent by assignment