EA201491513A1 - Рекомбинантные штаммы escherichia coli - Google Patents

Рекомбинантные штаммы escherichia coli

Info

Publication number
EA201491513A1
EA201491513A1 EA201491513A EA201491513A EA201491513A1 EA 201491513 A1 EA201491513 A1 EA 201491513A1 EA 201491513 A EA201491513 A EA 201491513A EA 201491513 A EA201491513 A EA 201491513A EA 201491513 A1 EA201491513 A1 EA 201491513A1
Authority
EA
Eurasian Patent Office
Prior art keywords
escherichia coli
recombinant strains
cell
recombinant
strains escherichia
Prior art date
Application number
EA201491513A
Other languages
English (en)
Russian (ru)
Inventor
Тобиас Эльшлегер
Эань Джэон Сэо
Ян Векамп
Эдуард Ф. Штанге
Ульрих Зонненборн
Йюрген Малинка
Ханс Пропперт
Original Assignee
Фарма-Централе Гмбх
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Фарма-Централе Гмбх filed Critical Фарма-Централе Гмбх
Publication of EA201491513A1 publication Critical patent/EA201491513A1/ru

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/1703Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • A61K38/1709Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • A61K38/1729Cationic antimicrobial peptides, e.g. defensins
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/4723Cationic antimicrobial peptides, e.g. defensins
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/66Microorganisms or materials therefrom
    • A61K35/74Bacteria
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K2035/11Medicinal preparations comprising living procariotic cells
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2319/00Fusion polypeptide
    • C07K2319/01Fusion polypeptide containing a localisation/targetting motif
    • C07K2319/036Fusion polypeptide containing a localisation/targetting motif targeting to the medium outside of the cell, e.g. type III secretion
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2319/00Fusion polypeptide
    • C07K2319/20Fusion polypeptide containing a tag with affinity for a non-protein ligand
    • C07K2319/21Fusion polypeptide containing a tag with affinity for a non-protein ligand containing a His-tag

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Organic Chemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Zoology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Toxicology (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Marine Sciences & Fisheries (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
EA201491513A 2012-02-17 2013-02-14 Рекомбинантные штаммы escherichia coli EA201491513A1 (ru)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP12001091.3A EP2628793A1 (en) 2012-02-17 2012-02-17 Recombinant escherichia coli strains
PCT/EP2013/000446 WO2013120618A1 (en) 2012-02-17 2013-02-14 Recombinant escherichia coli strains

Publications (1)

Publication Number Publication Date
EA201491513A1 true EA201491513A1 (ru) 2015-01-30

Family

ID=47843228

Family Applications (1)

Application Number Title Priority Date Filing Date
EA201491513A EA201491513A1 (ru) 2012-02-17 2013-02-14 Рекомбинантные штаммы escherichia coli

Country Status (9)

Country Link
US (1) US20160015781A1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
EP (1) EP2628793A1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
CN (1) CN104126003A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
AU (1) AU2013220738A1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
CA (1) CA2864870A1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
EA (1) EA201491513A1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
HK (1) HK1199060A1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
IN (1) IN2014DN06920A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
WO (1) WO2013120618A1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN110914386A (zh) 2017-06-12 2020-03-24 杜克大学 用于生产生物分子的组合物、系统和方法
CN109504643B (zh) * 2018-11-27 2022-06-10 扬州大学 整合四拷贝功能性f18菌毛操纵子基因的益生菌克隆株、构建方法及应用
US10485632B1 (en) 2018-11-27 2019-11-26 King Saud University Intraoral attachment clip for attachment of objects to edentulous ridges
WO2020165874A1 (en) * 2019-02-15 2020-08-20 Oncosimis Biotech Private Limited A bacterial expression vector for enhanced protein secretion
US12011466B2 (en) * 2019-07-08 2024-06-18 INSERM (Institut National de la Santé et de la Recherche Médicale) Modified Escherichia coli strain Nissle and treatment of gastrointestinal disorder
WO2022067219A1 (en) * 2020-09-28 2022-03-31 The Regents Of The University Of Michigan Methods and compositions for intestinal inflammation
CN115521884B (zh) * 2022-07-20 2023-12-29 四川宏展致远环保科技有限公司 一种类芽孢杆菌hnp12及其应用
CN116496916A (zh) * 2022-12-27 2023-07-28 安徽斯拜科生物科技有限公司 一种高产hbd-2的毕赤酵母工程菌株及其制备方法和应用
CN118931930B (zh) * 2023-05-09 2025-08-01 汤臣倍健股份有限公司 基于T7表达系统的Nissle 1917工程菌、其制备方法及应用
CN116769814B (zh) * 2023-06-16 2024-02-02 苏州泓迅生物科技股份有限公司 一种大肠杆菌益生菌t7表达系统及其应用

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2010049807A2 (en) * 2008-10-30 2010-05-06 Gene Bridges Gmbh Method for recombinant expression of polypeptides

Also Published As

Publication number Publication date
AU2013220738A1 (en) 2014-09-04
CA2864870A1 (en) 2013-08-22
CN104126003A (zh) 2014-10-29
HK1199060A1 (en) 2015-06-19
WO2013120618A1 (en) 2013-08-22
IN2014DN06920A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) 2015-04-10
EP2628793A1 (en) 2013-08-21
AU2013220738A9 (en) 2014-10-16
US20160015781A1 (en) 2016-01-21

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