EA201490380A1 - Терапия 3-гидроксиантраниловой кислотой (3-haa) для профилактики и лечения гиперлипидемии и ее сердечно-сосудистых осложнений - Google Patents
Терапия 3-гидроксиантраниловой кислотой (3-haa) для профилактики и лечения гиперлипидемии и ее сердечно-сосудистых осложненийInfo
- Publication number
- EA201490380A1 EA201490380A1 EA201490380A EA201490380A EA201490380A1 EA 201490380 A1 EA201490380 A1 EA 201490380A1 EA 201490380 A EA201490380 A EA 201490380A EA 201490380 A EA201490380 A EA 201490380A EA 201490380 A1 EA201490380 A1 EA 201490380A1
- Authority
- EA
- Eurasian Patent Office
- Prior art keywords
- haa
- hyperlipidemia
- acid
- heart
- hydroxiantranic
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
- A61K31/196—Carboxylic acids, e.g. valproic acid having an amino group the amino group being directly attached to a ring, e.g. anthranilic acid, mefenamic acid, diclofenac, chlorambucil
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/12—Drugs for disorders of the urinary system of the kidneys
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
Landscapes
- Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Epidemiology (AREA)
- Urology & Nephrology (AREA)
- Diabetes (AREA)
- Hospice & Palliative Care (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Vascular Medicine (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Peptides Or Proteins (AREA)
Abstract
Настоящее изобретение относится к применению метаболита триптофана, 3-гидроксиантраниловой кислоты (3-НАА) или ее функционального аналога для профилактического и/или терапевтического лечения млекопитающих, особенно людей, от гиперлипидемии и ее сердечно-сосудистых осложнений, т.е. образования атеросклеротических бляшек, инфаркта миокарда и сердечной недостаточности, ишемического инсульта и транзиторной ишемической атаки, поражения почек, аневризмы аорты и критической ишемии конечностей.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
SE1150728 | 2011-07-29 | ||
PCT/SE2012/050835 WO2013019156A1 (en) | 2011-07-29 | 2012-07-13 | 3-hydroxyanthranilic acid (3-haa) therapy for prevention and treatment of hyperlipidemia and its cardiovascular complications |
Publications (2)
Publication Number | Publication Date |
---|---|
EA201490380A1 true EA201490380A1 (ru) | 2014-06-30 |
EA023954B1 EA023954B1 (ru) | 2016-07-29 |
Family
ID=47629522
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
EA201490380A EA023954B1 (ru) | 2011-07-29 | 2012-07-13 | Терапия 3-гидроксиантраниловой кислотой (3-haa) для профилактики и лечения гиперлипидемии и ее сердечно-сосудистых осложнений |
Country Status (13)
Country | Link |
---|---|
US (1) | US20140296567A1 (ru) |
EP (1) | EP2736505B1 (ru) |
JP (1) | JP2014523925A (ru) |
KR (1) | KR20140060288A (ru) |
CN (1) | CN103841967A (ru) |
AU (1) | AU2012290734A1 (ru) |
CA (1) | CA2843401A1 (ru) |
EA (1) | EA023954B1 (ru) |
IL (1) | IL230694A0 (ru) |
IN (1) | IN2014CN00747A (ru) |
MX (1) | MX343138B (ru) |
WO (1) | WO2013019156A1 (ru) |
ZA (1) | ZA201400695B (ru) |
Families Citing this family (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2019006384A1 (en) * | 2017-06-30 | 2019-01-03 | Georgia State University Research Foundation, Inc. | TREATMENT OF ANEVRISM |
US11376248B2 (en) | 2017-06-30 | 2022-07-05 | Georgia State University Research Foundation, Inc. | Treatment of aneurysms |
WO2019147182A1 (en) * | 2018-01-29 | 2019-08-01 | Medscienta Ab | Antiatherosclerotic agents |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US2652332A (en) * | 1951-07-19 | 1953-09-15 | Harold S Olcott | Stabilization of lipoidal substances |
KR20080016859A (ko) * | 2005-05-16 | 2008-02-22 | 앤지오젠 파마슈티칼스 피티와이. 리미티드 | 통증의 치료를 위한 방법 및 조성물 |
AU2009286734A1 (en) * | 2008-08-26 | 2010-03-04 | Boehringer Ingelheim International Gmbh | Thienopyrimidines for pharmaceutical compositions |
US9090932B2 (en) * | 2009-11-27 | 2015-07-28 | Japan Science And Technology Agency | Method for screening of therapeutic agent for hyperlipemia |
CN106890149A (zh) * | 2009-12-30 | 2017-06-27 | 有限公司公元前世界医药 | 包括二甲双胍和瑞舒伐他汀的药物组合物 |
-
2012
- 2012-07-13 AU AU2012290734A patent/AU2012290734A1/en not_active Abandoned
- 2012-07-13 US US14/236,017 patent/US20140296567A1/en not_active Abandoned
- 2012-07-13 IN IN747CHN2014 patent/IN2014CN00747A/en unknown
- 2012-07-13 MX MX2014001225A patent/MX343138B/es active IP Right Grant
- 2012-07-13 EA EA201490380A patent/EA023954B1/ru not_active IP Right Cessation
- 2012-07-13 KR KR1020147003709A patent/KR20140060288A/ko not_active Application Discontinuation
- 2012-07-13 EP EP12820828.7A patent/EP2736505B1/en not_active Not-in-force
- 2012-07-13 JP JP2014523889A patent/JP2014523925A/ja active Pending
- 2012-07-13 CA CA2843401A patent/CA2843401A1/en not_active Abandoned
- 2012-07-13 CN CN201280043297.9A patent/CN103841967A/zh active Pending
- 2012-07-13 WO PCT/SE2012/050835 patent/WO2013019156A1/en active Application Filing
-
2014
- 2014-01-28 IL IL230694A patent/IL230694A0/en unknown
- 2014-01-29 ZA ZA2014/00695A patent/ZA201400695B/en unknown
Also Published As
Publication number | Publication date |
---|---|
KR20140060288A (ko) | 2014-05-19 |
AU2012290734A1 (en) | 2014-02-20 |
EP2736505A4 (en) | 2014-12-24 |
IL230694A0 (en) | 2014-03-31 |
ZA201400695B (en) | 2015-10-28 |
EA023954B1 (ru) | 2016-07-29 |
JP2014523925A (ja) | 2014-09-18 |
CA2843401A1 (en) | 2013-02-07 |
EP2736505A1 (en) | 2014-06-04 |
EP2736505B1 (en) | 2017-09-27 |
CN103841967A (zh) | 2014-06-04 |
MX343138B (es) | 2016-10-25 |
WO2013019156A1 (en) | 2013-02-07 |
MX2014001225A (es) | 2014-09-22 |
US20140296567A1 (en) | 2014-10-02 |
IN2014CN00747A (ru) | 2015-04-03 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
MM4A | Lapse of a eurasian patent due to non-payment of renewal fees within the time limit in the following designated state(s) |
Designated state(s): AM AZ BY KZ KG TJ TM RU |