EA201301205A1 - Способ предупреждения и/или лечения плоскоклеточного рака головы и шеи и композиция в нем используемая - Google Patents

Способ предупреждения и/или лечения плоскоклеточного рака головы и шеи и композиция в нем используемая

Info

Publication number
EA201301205A1
EA201301205A1 EA201301205A EA201301205A EA201301205A1 EA 201301205 A1 EA201301205 A1 EA 201301205A1 EA 201301205 A EA201301205 A EA 201301205A EA 201301205 A EA201301205 A EA 201301205A EA 201301205 A1 EA201301205 A1 EA 201301205A1
Authority
EA
Eurasian Patent Office
Prior art keywords
prevention
treatment
head
platy
composition used
Prior art date
Application number
EA201301205A
Other languages
English (en)
Inventor
Хемант К. Рой
Рамеш К. Уали
Дхананджай Кунте
Original Assignee
Носшор Юнивесити Хелссистем
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Носшор Юнивесити Хелссистем filed Critical Носшор Юнивесити Хелссистем
Publication of EA201301205A1 publication Critical patent/EA201301205A1/ru

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/74Synthetic polymeric materials
    • A61K31/765Polymers containing oxygen
    • A61K31/77Polymers containing oxygen of oxiranes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/075Ethers or acetals
    • A61K31/08Ethers or acetals acyclic, e.g. paraformaldehyde
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/335Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/337Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having four-membered rings, e.g. taxol
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/513Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim having oxo groups directly attached to the heterocyclic ring, e.g. cytosine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/74Synthetic polymeric materials
    • A61K31/765Polymers containing oxygen
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • A61P35/04Antineoplastic agents specific for metastasis
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C43/00Ethers; Compounds having groups, groups or groups
    • C07C43/02Ethers
    • C07C43/03Ethers having all ether-oxygen atoms bound to acyclic carbon atoms
    • C07C43/04Saturated ethers
    • C07C43/10Saturated ethers of polyhydroxy compounds
    • C07C43/11Polyethers containing —O—(C—C—O—)n units with ≤ 2 n≤ 10
    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08LCOMPOSITIONS OF MACROMOLECULAR COMPOUNDS
    • C08L71/00Compositions of polyethers obtained by reactions forming an ether link in the main chain; Compositions of derivatives of such polymers
    • C08L71/02Polyalkylene oxides
    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08LCOMPOSITIONS OF MACROMOLECULAR COMPOUNDS
    • C08L2203/00Applications
    • C08L2203/02Applications for biomedical use

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Polymers & Plastics (AREA)
  • Oncology (AREA)
  • Molecular Biology (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)

Abstract

Раскрыты композиции, содержащие полиэтиленгликоль (ПЭГ), для профилактики и/или лечения плоскоклеточного рака головы и шеи (ПКРГШ). Также раскрыты способы профилактики и/или лечения ПКРГШ, которые включают введение эффективного количества ПЭГ. Кроме того, раскрыты способы и композиции для подавления поверхностной экспрессии рецептора эпидермального фактора роста (РЭФР).
EA201301205A 2011-04-27 2012-04-27 Способ предупреждения и/или лечения плоскоклеточного рака головы и шеи и композиция в нем используемая EA201301205A1 (ru)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201161479493P 2011-04-27 2011-04-27
PCT/US2012/035434 WO2012149302A1 (en) 2011-04-27 2012-04-27 Compositions and methods

Publications (1)

Publication Number Publication Date
EA201301205A1 true EA201301205A1 (ru) 2014-04-30

Family

ID=47072771

Family Applications (1)

Application Number Title Priority Date Filing Date
EA201301205A EA201301205A1 (ru) 2011-04-27 2012-04-27 Способ предупреждения и/или лечения плоскоклеточного рака головы и шеи и композиция в нем используемая

Country Status (14)

Country Link
US (1) US20140050724A1 (ru)
EP (1) EP2702030A4 (ru)
JP (1) JP2014513103A (ru)
KR (1) KR20140033370A (ru)
CN (1) CN103619792A (ru)
AR (1) AR086207A1 (ru)
AU (1) AU2012249494A1 (ru)
BR (1) BR112013027369A2 (ru)
CA (1) CA2834395A1 (ru)
EA (1) EA201301205A1 (ru)
MX (1) MX2013012337A (ru)
TW (1) TW201311255A (ru)
WO (1) WO2012149302A1 (ru)
ZA (1) ZA201308892B (ru)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2012333100A1 (en) * 2011-09-09 2014-03-20 Amgen Inc. Use of human papillomavirus status in establishing use of an agent that binds EGFr in the treatment of cancer
US20200323811A1 (en) * 2016-05-24 2020-10-15 Industry-University Cooperation Foundation Hanyang University Intranasal pharmaceutical composition comprising anticancer drugcontaining nanoparticles for treating brain diseases
US20200069607A1 (en) * 2016-12-07 2020-03-05 The Board Of Regents Of The University Of Texas System Mouthwash for treating oral cancers
EA202092147A1 (ru) * 2018-03-13 2021-03-04 Иннейт Фарма Лечение рака головы и шеи
JP7487220B2 (ja) 2019-03-05 2024-05-20 ダウ グローバル テクノロジーズ エルエルシー カスパーゼ活性を誘導するためのポリエチレングリコール誘導体
CN112400801B (zh) * 2020-12-07 2022-07-22 天津医科大学第二医院 一种喉癌前病变动物模型及其构建方法和应用

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPWO2006085517A1 (ja) * 2005-02-08 2008-06-26 株式会社光ケミカル研究所 クロリン類及びポルフィリン類のpdt用軟膏製剤及び坐剤
US9173835B2 (en) * 2005-05-10 2015-11-03 Dermipsor Ltd. Compositions and methods for treating hyperproliferative epidermal diseases
CU23432B6 (es) * 2005-11-02 2009-10-16 Ct Ingenieria Genetica Biotech Formulaciones estabilizadas que contienen a los interferones gamma y alfa en proporciones potenciadoras
CN101147725B (zh) * 2006-09-21 2012-05-16 杨立新 一种用于阴道给药的酮康唑栓剂组合物
AU2007314501B2 (en) * 2006-09-28 2013-05-23 Merck Sharp & Dohme Corp. Use of pegylated IL-10 to treat cancer
US20110077263A1 (en) * 2009-09-29 2011-03-31 University Of Southern California Methods and Compositions of Toll-Like Receptor (TLR) Agonists

Also Published As

Publication number Publication date
KR20140033370A (ko) 2014-03-18
TW201311255A (zh) 2013-03-16
US20140050724A1 (en) 2014-02-20
AR086207A1 (es) 2013-11-27
CA2834395A1 (en) 2012-11-01
MX2013012337A (es) 2014-04-16
AU2012249494A1 (en) 2013-05-02
EP2702030A4 (en) 2014-09-10
ZA201308892B (en) 2016-08-31
BR112013027369A2 (pt) 2017-01-17
CN103619792A (zh) 2014-03-05
JP2014513103A (ja) 2014-05-29
EP2702030A1 (en) 2014-03-05
WO2012149302A1 (en) 2012-11-01

Similar Documents

Publication Publication Date Title
EA201301205A1 (ru) Способ предупреждения и/или лечения плоскоклеточного рака головы и шеи и композиция в нем используемая
WO2014062720A3 (en) Methods of treating cancer
MX2022010703A (es) Marcadores selectivamente desregulados en celulas t reguladoras, infiltrantes de tumores.
MY181086A (en) Anti-egfr antibodies and uses thereof
MX339862B (es) Compuestos imidazopiridinil-aminopiridina substituidos.
AR091220A1 (es) Metodos para tratar cancer usando antagonistas de union a pd-1 axis y antagonistas de vegf
MX350861B (es) Anticuerpos frente al receptor del factor de crecimiento epidérmico (egfr) y usos de éstos.
CA2900335C (en) Synthetic analogs of epipolythiodioxopiperazines and uses thereof
MX370721B (es) Compuestos y composiciones novedosas para atacar las células madre del cáncer.
EA201001196A1 (ru) Соединения 4-пиридинона и их применение для лечения рака
MX2016012933A (es) Composiciones de relleno de tejidos y metodos de uso.
MX360774B (es) Antagonistas de progesterona.
GB201014026D0 (en) Treatment
EA201491609A1 (ru) Модуляторы x рецепторов печени
NO20180002A1 (en) Aminobenzisoxazole compounds as agonists of A7-nicotinic acetylcholine receptors
MX2014009750A (es) Composiciones antifungicas para el tratamiento de piel y uñas.
WO2012169822A3 (ko) 암세포 증식 억제와 혈관신생 억제를 위한 융합 단백질 및 이를 포함한 항암 조성물
MX358501B (es) Combinación farmacéutica de sinergia para el tratamiento del carcinoma de célula escamosa de cabeza y cuello.
PH12015500185A1 (en) Azaheterocycles as bir2 and/or bir3 inhibitors
WO2018106794A3 (en) Compositions and methods relating to molecular cerium-oxide nanoclusters
MX2015012580A (es) El uso de sdf-1 para atenuar la formacion de cicatrices.
MX2013004963A (es) Polietilenglicol (peg) o copolimeros de bloqueo de bloque de polietilenglicol (peg) para el tratamiento de cancer colorrectal.
WO2012170742A3 (en) Treatment and prevention of cancer with hmgb1 antagonists
EA201590521A1 (ru) Инъекционные раковые композиции
WO2015112866A3 (en) Compounds and methods for increasing hair growth