EA201290098A1 - Способ получения полимерных композиций на основе проантоцианидина для фармацевтических форм - Google Patents

Способ получения полимерных композиций на основе проантоцианидина для фармацевтических форм

Info

Publication number
EA201290098A1
EA201290098A1 EA201290098A EA201290098A EA201290098A1 EA 201290098 A1 EA201290098 A1 EA 201290098A1 EA 201290098 A EA201290098 A EA 201290098A EA 201290098 A EA201290098 A EA 201290098A EA 201290098 A1 EA201290098 A1 EA 201290098A1
Authority
EA
Eurasian Patent Office
Prior art keywords
proantocyanidine
pharmaceutical forms
proanthocyanidin
compositions based
polymeric compositions
Prior art date
Application number
EA201290098A
Other languages
English (en)
Other versions
EA023814B1 (ru
Inventor
Джон Чоу
Нитин Прадхан
Суреш Махадев Кадам
Инчжун Чэнь
Джонатан Тсэнг
Мубин Ахмед Кхан
Випин Кумар Пандей
Original Assignee
Гленмарк Фармасьютикалс Лтд.
Напо Фармасьютикалс Инк.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Гленмарк Фармасьютикалс Лтд., Напо Фармасьютикалс Инк. filed Critical Гленмарк Фармасьютикалс Лтд.
Publication of EA201290098A1 publication Critical patent/EA201290098A1/ru
Publication of EA023814B1 publication Critical patent/EA023814B1/ru

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
    • A61K31/352—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom condensed with carbocyclic rings, e.g. methantheline 
    • A61K31/353—3,4-Dihydrobenzopyrans, e.g. chroman, catechin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/38—Clusiaceae, Hypericaceae or Guttiferae (Hypericum or Mangosteen family), e.g. common St. Johnswort
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/47—Euphorbiaceae (Spurge family), e.g. Ricinus (castorbean)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0087—Galenical forms not covered by A61K9/02 - A61K9/7023
    • A61K9/0095—Drinks; Beverages; Syrups; Compositions for reconstitution thereof, e.g. powders or tablets to be dispersed in a glass of water; Veterinary drenches
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A61K9/2806—Coating materials
    • A61K9/2833—Organic macromolecular compounds
    • A61K9/284—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone
    • A61K9/2846—Poly(meth)acrylates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5005—Wall or coating material
    • A61K9/5021—Organic macromolecular compounds
    • A61K9/5026—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5073—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings
    • A61K9/5078—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings with drug-free core
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/12—Antidiarrhoeals

Abstract

Предложены способы получения фармацевтических композиций, содержащих проантоцианидиновый полимер, применяемых для лечения и профилактики различных состояний. В частности, изобретение относится к способу получения фармацевтических форм полимерной композиции на основе проантоцианидина, которая была выделена из Croton spp. или Calophyllum spp. В частности, изобретение относится к способу получения полимерных композиций на основе проантоцианидина, обеспечивающих достижение концентраций и степеней чистоты, подходящих для добавления к фармацевтически эффективным формам.
EA201290098A 2009-08-26 2010-08-24 Способ получения полимерных композиций на основе проантоцианидина для фармацевтических форм EA023814B1 (ru)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IN1962MU2009 2009-08-26
PCT/IB2010/002060 WO2011024049A2 (en) 2009-08-26 2010-08-24 Method for producing proanthocyanidin polymer compositions for pharmaceutical formulations

Publications (2)

Publication Number Publication Date
EA201290098A1 true EA201290098A1 (ru) 2013-01-30
EA023814B1 EA023814B1 (ru) 2016-07-29

Family

ID=43337818

Family Applications (1)

Application Number Title Priority Date Filing Date
EA201290098A EA023814B1 (ru) 2009-08-26 2010-08-24 Способ получения полимерных композиций на основе проантоцианидина для фармацевтических форм

Country Status (3)

Country Link
EA (1) EA023814B1 (ru)
WO (1) WO2011024049A2 (ru)
ZA (1) ZA201202160B (ru)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2639291C2 (ru) * 2016-03-29 2017-12-20 Федеральное государственное автономное образовательное учреждение высшего образования "Белгородский государственный национальный исследовательский университет" (НИУ "БелГУ") Способ получения и состав для получения сухих форм антоцианов синего цвета

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BR112013010774A2 (pt) 2010-10-31 2017-03-21 Napo Pharmaceuticals Inc "usos de crofelemer no tratamento de diarreia associada ao hiv"
BR112013018688B1 (pt) * 2011-01-27 2021-08-24 Napo Pharmaceuticals, Inc Método de produção de uma composição polimérica de proantocianidina
CN102210538A (zh) * 2011-05-04 2011-10-12 惠州市欧野科技有限公司 一种沉香木粉与乳胶混合枕及其制作方法
WO2013093655A1 (en) * 2011-12-22 2013-06-27 Glenmark Pharmaceuticals Limited Non-enteric pharmaceutical composition comprising crofelemer
ES2917425T3 (es) * 2013-06-07 2022-07-08 Shrivastava Remi Una composición para aplicación tópica que comprende glicerol y taninos
WO2015184111A1 (en) * 2014-05-29 2015-12-03 Jaguar Animal Health, Inc. Methods of treating salmonella-induced diarrhea in non-human animals
WO2015184109A1 (en) * 2014-05-29 2015-12-03 Jaguar Animal Health, Inc. Methods of treating diarrhea in adult non-human animals
CN105294636B (zh) * 2015-11-16 2018-11-27 大兴安岭林格贝寒带生物科技股份有限公司 一种制备低聚原花青素的方法
US20220088102A1 (en) * 2020-09-22 2022-03-24 Alphyn Biologics, Llc Croton lechleri compositions and their use in the treatment of cystic fibrosis
WO2022066803A1 (en) * 2020-09-22 2022-03-31 Alphyn Biologics, Llc Topical croton lechleri compositions and their use in the treatment of a bacterial colonization or primary or secondary bacterial infection of an underlying skin disorder
US20220265750A1 (en) * 2021-02-25 2022-08-25 Alphyn Biologics, Llc Composition for treatment of topical dermatological bacterial skin conditions

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5211944A (en) 1990-10-12 1993-05-18 Shaman Pharmaceuticals, Inc. Proanthocyanidin polymers having antiviral activity and methods of obtaining same
KR100467532B1 (ko) * 1996-10-16 2005-01-24 피에스 팔마큐티칼스 인코퍼레이션 프로안토시아니딘 중합체로 된 항-설사 장용피 조제물
WO2000047062A2 (en) * 1999-02-01 2000-08-17 Shaman Pharmaceuticals, Inc. Enteric formulations of proanthocyanidin polymer dietary supplements and methods for preparing same
WO2007130893A2 (en) * 2006-05-01 2007-11-15 Napo Pharmaceuticals, Inc. Compositions and methods for treating or preventing inflammatory bowel disease, familial adenomatous polyposis and colon cancer

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2639291C2 (ru) * 2016-03-29 2017-12-20 Федеральное государственное автономное образовательное учреждение высшего образования "Белгородский государственный национальный исследовательский университет" (НИУ "БелГУ") Способ получения и состав для получения сухих форм антоцианов синего цвета

Also Published As

Publication number Publication date
EA023814B1 (ru) 2016-07-29
WO2011024049A2 (en) 2011-03-03
WO2011024049A9 (en) 2013-04-25
WO2011024049A3 (en) 2011-05-19
ZA201202160B (en) 2013-08-28

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Legal Events

Date Code Title Description
MM4A Lapse of a eurasian patent due to non-payment of renewal fees within the time limit in the following designated state(s)

Designated state(s): AM AZ BY KZ KG MD TJ TM

MM4A Lapse of a eurasian patent due to non-payment of renewal fees within the time limit in the following designated state(s)

Designated state(s): RU

NF4A Restoration of lapsed right to a eurasian patent

Designated state(s): RU