EA201270607A1 - Аденовирус обезьян и способы его использования - Google Patents
Аденовирус обезьян и способы его использованияInfo
- Publication number
- EA201270607A1 EA201270607A1 EA201270607A EA201270607A EA201270607A1 EA 201270607 A1 EA201270607 A1 EA 201270607A1 EA 201270607 A EA201270607 A EA 201270607A EA 201270607 A EA201270607 A EA 201270607A EA 201270607 A1 EA201270607 A1 EA 201270607A1
- Authority
- EA
- Eurasian Patent Office
- Prior art keywords
- monkey
- adenovirus
- methods
- provides
- human
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/66—Microorganisms or materials therefrom
- A61K35/76—Viruses; Subviral particles; Bacteriophages
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
- C07K14/01—DNA viruses
- C07K14/075—Adenoviridae
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
- C07K14/08—RNA viruses
- C07K14/15—Retroviridae, e.g. bovine leukaemia virus, feline leukaemia virus human T-cell leukaemia-lymphoma virus
- C07K14/155—Lentiviridae, e.g. visna-maedi virus, equine infectious virus, FIV, SIV
- C07K14/16—HIV-1 ; HIV-2
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
- C07K14/35—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Mycobacteriaceae (F)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
- C12N15/86—Viral vectors
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N7/00—Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
- C12N2710/00011—Details
- C12N2710/10011—Adenoviridae
- C12N2710/10311—Mastadenovirus, e.g. human or simian adenoviruses
- C12N2710/10322—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
- C12N2710/00011—Details
- C12N2710/10011—Adenoviridae
- C12N2710/10311—Mastadenovirus, e.g. human or simian adenoviruses
- C12N2710/10332—Use of virus as therapeutic agent, other than vaccine, e.g. as cytolytic agent
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
- C12N2710/00011—Details
- C12N2710/10011—Adenoviridae
- C12N2710/10311—Mastadenovirus, e.g. human or simian adenoviruses
- C12N2710/10341—Use of virus, viral particle or viral elements as a vector
- C12N2710/10343—Use of virus, viral particle or viral elements as a vector viral genome or elements thereof as genetic vector
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
- C12N2710/00011—Details
- C12N2710/10011—Adenoviridae
- C12N2710/10311—Mastadenovirus, e.g. human or simian adenoviruses
- C12N2710/10351—Methods of production or purification of viral material
- C12N2710/10352—Methods of production or purification of viral material relating to complementing cells and packaging systems for producing virus or viral particles
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Genetics & Genomics (AREA)
- Virology (AREA)
- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Medicinal Chemistry (AREA)
- Molecular Biology (AREA)
- Biophysics (AREA)
- Biomedical Technology (AREA)
- General Engineering & Computer Science (AREA)
- Biotechnology (AREA)
- Microbiology (AREA)
- Gastroenterology & Hepatology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Immunology (AREA)
- Physics & Mathematics (AREA)
- Plant Pathology (AREA)
- AIDS & HIV (AREA)
- Communicable Diseases (AREA)
- Hematology (AREA)
- Oncology (AREA)
- Mycology (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Abstract
Изобретение представляет способы репродукции аденовируса обезьян в клетке, в том числе клетке человека, содержащей один или несколько продуктов генов, выделенных из аденовируса человека. Кроме того, изобретение представляет способы репродукции, в которых аденовирус обезьян содержит нуклеотидную последовательность, кодирующую продукт гена аденовируса человека. Кроме того, настоящее изобретение представляет аденовирус обезьян, включая аденовирус обезьян, дефектный по репликации, полученный с помощью таких способов репродукции.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US25934309P | 2009-11-09 | 2009-11-09 | |
PCT/US2010/055991 WO2011057248A2 (en) | 2009-11-09 | 2010-11-09 | Simian adenovirus and methods of use |
Publications (1)
Publication Number | Publication Date |
---|---|
EA201270607A1 true EA201270607A1 (ru) | 2012-09-28 |
Family
ID=43577533
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
EA201270607A EA201270607A1 (ru) | 2009-11-09 | 2010-11-09 | Аденовирус обезьян и способы его использования |
Country Status (12)
Country | Link |
---|---|
US (2) | US9133248B2 (ru) |
EP (2) | EP2853266B1 (ru) |
JP (2) | JP5980117B2 (ru) |
KR (1) | KR20120139672A (ru) |
CN (1) | CN102770146B (ru) |
AU (1) | AU2010314842A1 (ru) |
BR (1) | BR112012010824A2 (ru) |
CA (1) | CA2779632C (ru) |
EA (1) | EA201270607A1 (ru) |
IL (1) | IL219492A0 (ru) |
MX (1) | MX2012005181A (ru) |
WO (1) | WO2011057248A2 (ru) |
Families Citing this family (13)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2011057248A2 (en) * | 2009-11-09 | 2011-05-12 | Genvec, Inc. | Simian adenovirus and methods of use |
WO2012021730A2 (en) | 2010-08-11 | 2012-02-16 | Genvec, Inc. | Respiratory syncytial virus (rsv) vaccine |
BR112014008284A2 (pt) | 2011-10-05 | 2020-10-27 | Genvec Inc. | adenovirus (gorilla) simian ou vetores adenovirais e métodos de uso |
JP6757119B2 (ja) | 2011-10-05 | 2020-09-16 | ジェンヴェック エルエルシー | アーフェンアデノウイルス(ゴリラ)又はアデノウイルスベクター、及び使用方法 |
CN107937440A (zh) | 2011-10-05 | 2018-04-20 | 金维克有限公司 | 猴腺病毒(大猩猩)或腺病毒载体及其使用方法 |
EP2764011B1 (en) * | 2011-10-05 | 2021-04-07 | GenVec, Inc. | Adenoviral vector-based respiratory syncytial virus (rsv) vaccine |
WO2013180967A1 (en) | 2012-05-29 | 2013-12-05 | Genvec, Inc. | Herpes simplex virus vaccine |
CA3200425A1 (en) * | 2012-11-16 | 2014-05-22 | Peter ABBINK | Recombinant adenoviruses and use thereof |
US10376549B2 (en) * | 2015-01-20 | 2019-08-13 | Adcure Biotechnologies, Llc. | Detargeted adenovirus variants and related methods |
US9982276B2 (en) * | 2015-03-12 | 2018-05-29 | Adcure Biotechnologies, Llc. | Penton-mutated, integrin-retargeted adenovirus vectors with reduced toxicity and their use |
BR112020007695A2 (pt) * | 2017-10-31 | 2020-10-20 | Janssen Vaccines & Prevention B.V. | adenovírus e seus usos |
WO2019118480A1 (en) | 2017-12-11 | 2019-06-20 | Beth Israel Deaconess Medical Center, Inc. | Recombinant adenoviruses and uses thereof |
CN113637705B (zh) * | 2021-08-19 | 2024-03-01 | 中国疾病预防控制中心病毒病预防控制所 | 猴1型腺病毒(SAdV-1)载体系统及其应用 |
Family Cites Families (48)
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GB9223084D0 (en) | 1992-11-04 | 1992-12-16 | Imp Cancer Res Tech | Compounds to target cells |
FR2705686B1 (fr) | 1993-05-28 | 1995-08-18 | Transgene Sa | Nouveaux adénovirus défectifs et lignées de complémentation correspondantes. |
CA2144040A1 (fr) | 1993-07-13 | 1995-01-26 | Michel Perricaudet | Vecteurs adenoviraux defectifs et utilisation en therapie genique |
US5543328A (en) | 1993-08-13 | 1996-08-06 | Genetic Therapy, Inc. | Adenoviruses having modified fiber proteins |
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JP5882741B2 (ja) | 2009-02-02 | 2016-03-09 | グラクソスミスクライン バイオロジカルズ ソシエテ アノニム | サルアデノウイルスの核酸配列及びアミノ酸配列、それを含有するベクター、並びにその使用 |
WO2011057248A2 (en) * | 2009-11-09 | 2011-05-12 | Genvec, Inc. | Simian adenovirus and methods of use |
-
2010
- 2010-11-09 WO PCT/US2010/055991 patent/WO2011057248A2/en active Application Filing
- 2010-11-09 CN CN201080061001.7A patent/CN102770146B/zh active Active
- 2010-11-09 US US13/508,659 patent/US9133248B2/en active Active
- 2010-11-09 AU AU2010314842A patent/AU2010314842A1/en not_active Abandoned
- 2010-11-09 EP EP14192324.3A patent/EP2853266B1/en active Active
- 2010-11-09 BR BR112012010824A patent/BR112012010824A2/pt not_active IP Right Cessation
- 2010-11-09 EA EA201270607A patent/EA201270607A1/ru unknown
- 2010-11-09 EP EP10782478.1A patent/EP2498791B1/en active Active
- 2010-11-09 MX MX2012005181A patent/MX2012005181A/es not_active Application Discontinuation
- 2010-11-09 JP JP2012538080A patent/JP5980117B2/ja active Active
- 2010-11-09 CA CA2779632A patent/CA2779632C/en active Active
- 2010-11-09 KR KR1020127014130A patent/KR20120139672A/ko not_active Application Discontinuation
-
2012
- 2012-04-30 IL IL219492A patent/IL219492A0/en unknown
-
2015
- 2015-08-04 US US14/817,910 patent/US9586998B2/en active Active
-
2016
- 2016-03-10 JP JP2016046728A patent/JP6277213B2/ja active Active
Also Published As
Publication number | Publication date |
---|---|
US20150329834A1 (en) | 2015-11-19 |
US9133248B2 (en) | 2015-09-15 |
US9586998B2 (en) | 2017-03-07 |
WO2011057248A3 (en) | 2011-09-15 |
JP2013509887A (ja) | 2013-03-21 |
CN102770146A (zh) | 2012-11-07 |
AU2010314842A1 (en) | 2012-05-31 |
JP5980117B2 (ja) | 2016-08-31 |
EP2853266B1 (en) | 2018-01-31 |
US20120225470A1 (en) | 2012-09-06 |
KR20120139672A (ko) | 2012-12-27 |
CA2779632A1 (en) | 2011-05-12 |
IL219492A0 (en) | 2012-06-28 |
EP2498791B1 (en) | 2014-12-24 |
CA2779632C (en) | 2019-08-20 |
EP2498791A2 (en) | 2012-09-19 |
EP2853266A1 (en) | 2015-04-01 |
CN102770146B (zh) | 2016-02-03 |
BR112012010824A2 (pt) | 2018-03-06 |
JP6277213B2 (ja) | 2018-02-07 |
WO2011057248A2 (en) | 2011-05-12 |
JP2016146838A (ja) | 2016-08-18 |
MX2012005181A (es) | 2012-08-01 |
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