EA201170688A1 - Способ наноэмульгации куркумина и производных куркумина - Google Patents

Способ наноэмульгации куркумина и производных куркумина

Info

Publication number
EA201170688A1
EA201170688A1 EA201170688A EA201170688A EA201170688A1 EA 201170688 A1 EA201170688 A1 EA 201170688A1 EA 201170688 A EA201170688 A EA 201170688A EA 201170688 A EA201170688 A EA 201170688A EA 201170688 A1 EA201170688 A1 EA 201170688A1
Authority
EA
Eurasian Patent Office
Prior art keywords
curkumin
emulgence
nuro
derivatives
nonionic
Prior art date
Application number
EA201170688A
Other languages
English (en)
Other versions
EA019446B1 (ru
Inventor
Анитха Кришнан Наир
Рамчханд Нанаппан Чханийилпарампу
Бхупатхираджу Киран
Рама Раджу Гокараджу
Ганга Раджу Гокараджу
Тримуртулу Голакоти
Original Assignee
Лайла Фармасьютикалз Пвт. Лтд.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Лайла Фармасьютикалз Пвт. Лтд. filed Critical Лайла Фармасьютикалз Пвт. Лтд.
Publication of EA201170688A1 publication Critical patent/EA201170688A1/ru
Publication of EA019446B1 publication Critical patent/EA019446B1/ru

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/88—Liliopsida (monocotyledons)
    • A61K36/906—Zingiberaceae (Ginger family)
    • A61K36/9066—Curcuma, e.g. common turmeric, East Indian arrowroot or mango ginger
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
    • A23V2250/00—Food ingredients
    • A23V2250/20—Natural extracts
    • A23V2250/21—Plant extracts
    • A23V2250/2112—Curcumin, turmeric
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/141—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
    • A61K9/145—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with organic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/51—Nanocapsules; Nanoparticles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/51—Nanocapsules; Nanoparticles
    • A61K9/5107—Excipients; Inactive ingredients
    • A61K9/5123—Organic compounds, e.g. fats, sugars
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S977/00—Nanotechnology
    • Y10S977/70—Nanostructure
    • Y10S977/773—Nanoparticle, i.e. structure having three dimensions of 100 nm or less
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S977/00—Nanotechnology
    • Y10S977/902—Specified use of nanostructure
    • Y10S977/904—Specified use of nanostructure for medical, immunological, body treatment, or diagnosis
    • Y10S977/915—Therapeutic or pharmaceutical composition

Landscapes

  • Health & Medical Sciences (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Botany (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Mycology (AREA)
  • Microbiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medical Informatics (AREA)
  • Alternative & Traditional Medicine (AREA)
  • Biotechnology (AREA)
  • Organic Chemistry (AREA)
  • Ophthalmology & Optometry (AREA)
  • Rheumatology (AREA)
  • Pain & Pain Management (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

В данном документе раскрыт способ наноэмульгации сильно липофильных полифенольных соединений с применением неионного поверхностно-активного вещества и неионного сорастворителя с помощью звуковой энергии для увеличения водной растворимости.
EA201170688A 2008-11-17 2009-11-17 Способ наноэмульгирования куркумина и производных куркумина EA019446B1 (ru)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IN2828CH2008 2008-11-17
PCT/IN2009/000651 WO2010070665A2 (en) 2008-11-17 2009-11-17 A process for nanoemulsification of curcumin and derivatives of curcumin

Publications (2)

Publication Number Publication Date
EA201170688A1 true EA201170688A1 (ru) 2011-12-30
EA019446B1 EA019446B1 (ru) 2014-03-31

Family

ID=42269179

Family Applications (1)

Application Number Title Priority Date Filing Date
EA201170688A EA019446B1 (ru) 2008-11-17 2009-11-17 Способ наноэмульгирования куркумина и производных куркумина

Country Status (8)

Country Link
US (1) US8632815B2 (ru)
EP (1) EP2346492A4 (ru)
JP (1) JP5528472B2 (ru)
CN (1) CN102202652A (ru)
AU (1) AU2009329025A1 (ru)
CA (1) CA2743965A1 (ru)
EA (1) EA019446B1 (ru)
WO (1) WO2010070665A2 (ru)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP5528472B2 (ja) * 2008-11-17 2014-06-25 ライラ ファーマシューティカルズ ピーブイティ．エルティディ． クルクミン及びクルクミン誘導体のナノ乳化法
JP2012510466A (ja) * 2008-12-01 2012-05-10 ライラ ファーマシューティカルズ ピーブイティ．エルティディ． 炎症、皮膚異常及び粘膜異常並びに他の皮膚疾病及び粘膜疾病の治療のための局部用製剤
JP6105475B2 (ja) * 2010-10-22 2017-03-29 ヴィズリ・ヘルス・サイエンスィズ・エルエルシー 可溶性の乏しい化合物の可溶性を増大させる方法ならびにそのような化合物の配合物を作る、および用いる方法
AU2013264767A1 (en) * 2012-05-22 2014-11-27 Laila Pharmaceuticals Pvt. Ltd. Novel highly bioavailable, water soluble and sustained release nanoformulations of hydrophobic plant derived compounds and extracts
DE202012012130U1 (de) 2012-12-19 2014-03-21 Aquanova Ag Curcuminsolubilisat
CN104224716B (zh) * 2014-10-14 2016-08-31 哈尔滨工业大学 利用纳米乳化技术生产纳米微粒的方法
US10085951B2 (en) 2014-12-11 2018-10-02 Designs For Health, Inc. Curcuminoid formulations and related methods of treatment
CN105315143B (zh) * 2015-10-16 2017-06-16 苏州大学 一种提高姜黄素水溶性及溶液光稳定性的方法
CA3038346C (en) 2019-01-31 2022-03-29 Nam Hai LAI Process for producing a nano-cbd microemulsion system

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4263333A (en) * 1979-09-12 1981-04-21 General Foods Corporation Curcumin-metal color complexes
US20030236236A1 (en) * 1999-06-30 2003-12-25 Feng-Jing Chen Pharmaceutical compositions and dosage forms for administration of hydrophobic drugs
KR100478001B1 (ko) 2002-06-21 2005-03-23 박계정 2축 밸런스 머신
US7968115B2 (en) * 2004-03-05 2011-06-28 Board Of Regents, The University Of Texas System Liposomal curcumin for treatment of cancer
WO2007043058A1 (en) * 2005-10-13 2007-04-19 Ganga Raju Gokaraju Process for producing enriched fractions of tetrahydroxycurcumin and tetrahydrotetrahydroxy-curcumin from the extracts of curcuma longa
CA2683777C (en) * 2007-04-13 2016-08-23 University Of North Texas Health Science Center At Fort Worth Formulation of active agent loaded activated plga nanoparticles for targeted cancer nano-therapeutics
WO2009067734A1 (en) * 2007-11-28 2009-06-04 Commonwealth Scientific And Industrial Research Organisation Nanoemulsions
WO2010010431A1 (en) * 2008-07-24 2010-01-28 National Institute Of Pharmaceutical Education And Research Self-nano-emulsifying curcuminoids composition with enhanced bioavailability
WO2010070664A1 (en) * 2008-11-17 2010-06-24 Laila Pharmaceuticals Pvt. Ltd. Curcuminoids and its metabolites for the application in ocular diseases
JP5528472B2 (ja) * 2008-11-17 2014-06-25 ライラ ファーマシューティカルズ ピーブイティ．エルティディ． クルクミン及びクルクミン誘導体のナノ乳化法

Also Published As

Publication number Publication date
JP5528472B2 (ja) 2014-06-25
AU2009329025A2 (en) 2011-06-02
EP2346492A4 (en) 2012-12-05
AU2009329025A1 (en) 2010-06-24
JP2012508794A (ja) 2012-04-12
CN102202652A (zh) 2011-09-28
EA019446B1 (ru) 2014-03-31
EP2346492A2 (en) 2011-07-27
WO2010070665A3 (en) 2010-10-28
WO2010070665A2 (en) 2010-06-24
CA2743965A1 (en) 2010-06-24
US8632815B2 (en) 2014-01-21
US20110229532A1 (en) 2011-09-22

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Legal Events

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MM4A Lapse of a eurasian patent due to non-payment of renewal fees within the time limit in the following designated state(s)

Designated state(s): AM AZ BY KZ KG MD TJ TM