EA201170606A1 - Феназопиридиновые соединения - Google Patents

Феназопиридиновые соединения

Info

Publication number
EA201170606A1
EA201170606A1 EA201170606A EA201170606A EA201170606A1 EA 201170606 A1 EA201170606 A1 EA 201170606A1 EA 201170606 A EA201170606 A EA 201170606A EA 201170606 A EA201170606 A EA 201170606A EA 201170606 A1 EA201170606 A1 EA 201170606A1
Authority
EA
Eurasian Patent Office
Prior art keywords
compounds
phenazopiridine
formula
relates
present
Prior art date
Application number
EA201170606A
Other languages
English (en)
Inventor
Сидни Хечт
Нур Эддин Фахми
Самир Д. Рой
Джордж Бонневиль
Original Assignee
Пиннэкл Фармасьютикалс, Инк.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=42269135&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=EA201170606(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Пиннэкл Фармасьютикалс, Инк. filed Critical Пиннэкл Фармасьютикалс, Инк.
Publication of EA201170606A1 publication Critical patent/EA201170606A1/ru

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/72—Nitrogen atoms
    • C07D213/76—Nitrogen atoms to which a second hetero atom is attached
    • C07D213/77—Hydrazine radicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/10—Drugs for disorders of the urinary system of the bladder
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P23/00—Anaesthetics
    • A61P23/02—Local anaesthetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/72—Nitrogen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Urology & Nephrology (AREA)
  • Pain & Pain Management (AREA)
  • Anesthesiology (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Rheumatology (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Pyridine Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Peptides Or Proteins (AREA)

Abstract

Настоящее изобретение относится к замещенным феназопиридинам, представленным формулой I. Настоящее изобретение также относится к повышенной биодоступности соединений формулы I по сравнению с несвязанным феназопиридином.
EA201170606A 2008-12-19 2009-12-21 Феназопиридиновые соединения EA201170606A1 (ru)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US13942808P 2008-12-19 2008-12-19
US23266309P 2009-08-10 2009-08-10
PCT/US2009/068963 WO2010071878A1 (en) 2008-12-19 2009-12-21 Phenazopyridine compounds

Publications (1)

Publication Number Publication Date
EA201170606A1 true EA201170606A1 (ru) 2011-12-30

Family

ID=42269135

Family Applications (1)

Application Number Title Priority Date Filing Date
EA201170606A EA201170606A1 (ru) 2008-12-19 2009-12-21 Феназопиридиновые соединения

Country Status (14)

Country Link
US (3) US7893042B2 (ru)
EP (1) EP2367426A4 (ru)
JP (1) JP2012512914A (ru)
KR (1) KR20110082601A (ru)
CN (1) CN102256486A (ru)
AU (1) AU2009327322A1 (ru)
BR (1) BRPI0923114A2 (ru)
CA (1) CA2747716A1 (ru)
CL (1) CL2011001515A1 (ru)
EA (1) EA201170606A1 (ru)
IL (1) IL213062A0 (ru)
MX (1) MX2011006075A (ru)
WO (1) WO2010071878A1 (ru)
ZA (1) ZA201103724B (ru)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EA201170606A1 (ru) 2008-12-19 2011-12-30 Пиннэкл Фармасьютикалс, Инк. Феназопиридиновые соединения
SI3331892T1 (sl) * 2015-08-06 2019-10-30 Hoffmann La Roche Postopki za pripravo derivatov gaINAc kisline
US11549888B2 (en) 2019-10-03 2023-01-10 Hach Company Method for measuring monochloramine in seawater
CA3211722A1 (en) * 2021-02-24 2022-09-01 Kashiv Biosciences, Llc Prodrugs of azo compounds and their salts

Family Cites Families (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4024A (en) * 1845-05-01 Cutting and crushing corn-fodder
US2135293A (en) * 1936-08-20 1938-11-01 Pyridium Corp Medicinal azo dyes
US3493555A (en) 1966-03-23 1970-02-03 Nepera Chem Co Inc 3-phenylazo-2,6-pyridyl dicyclopropane-carboxamide
USRE29640E (en) 1970-12-19 1978-05-23 Basf Aktiengesellschaft Certain substituted 2,6-diamino-4-methyl-nicotinitriles the corresponding nicotinamides and derivatives thereof
DE2251719A1 (de) 1972-10-21 1974-04-25 Basf Ag 6700 Ludwigshafen Dispersionsfarbstoffe der 2,6diaminopyridinreihe
US4829070A (en) * 1982-05-18 1989-05-09 University Of Florida Novel redox carriers for brain-specific drug delivery
JPH01193375A (ja) 1988-01-29 1989-08-03 Canon Inc 記録液
JPH0667467A (ja) 1992-08-25 1994-03-11 Mitsui Toatsu Chem Inc 後染色型カラートナー用色素及びカラートナー
IT1256111B (it) * 1992-11-23 1995-11-28 Lifegroup Spa Sali dell'acido traumatico ad attivita' cicatrizzante ed antibatterica
US7018654B2 (en) 1999-03-05 2006-03-28 New River Pharmaceuticals Inc. Pharmaceutical composition containing an active agent in an amino acid copolymer structure
US6716452B1 (en) 2000-08-22 2004-04-06 New River Pharmaceuticals Inc. Active agent delivery systems and methods for protecting and administering active agents
US7060708B2 (en) 1999-03-10 2006-06-13 New River Pharmaceuticals Inc. Active agent delivery systems and methods for protecting and administering active agents
US20040248963A1 (en) * 2001-11-23 2004-12-09 Bueno Melendo Ana Belen Prodrugs of excitatory amino acids
JP2004059687A (ja) 2002-07-26 2004-02-26 Fuji Photo Film Co Ltd 着色組成物、インクジェット記録用インク、インクジェット記録方法、感熱記録材料、カラートナー、およびカラーフィルター
US7589233B2 (en) 2003-07-29 2009-09-15 Signature R&D Holdings, Llc L-Threonine derivatives of high therapeutic index
NZ601780A (en) 2003-07-29 2012-10-26 Signature R & D Holdings Llc Amino Acid Prodrugs
US8173840B2 (en) 2003-07-29 2012-05-08 Signature R&D Holdings, Llc Compounds with high therapeutic index
WO2006114324A1 (en) * 2005-04-28 2006-11-02 Schering Ag Compounds comprising cyclized somatostatin receptor binding peptides
WO2007041677A2 (en) * 2005-10-03 2007-04-12 Combinatorx, Incorporated Soft tissue implants and drug combination compositions, and use thereof
GB0521549D0 (en) 2005-10-22 2005-11-30 Avecia Inkjet Ltd Yellow azo dyes for ink jet printing
EA201170606A1 (ru) 2008-12-19 2011-12-30 Пиннэкл Фармасьютикалс, Инк. Феназопиридиновые соединения

Also Published As

Publication number Publication date
EP2367426A1 (en) 2011-09-28
US7893042B2 (en) 2011-02-22
US20110319367A1 (en) 2011-12-29
US20100204185A1 (en) 2010-08-12
WO2010071878A1 (en) 2010-06-24
KR20110082601A (ko) 2011-07-19
US8288365B2 (en) 2012-10-16
CL2011001515A1 (es) 2012-07-20
IL213062A0 (en) 2011-07-31
MX2011006075A (es) 2011-09-27
CN102256486A (zh) 2011-11-23
BRPI0923114A2 (pt) 2015-08-11
US20130040917A1 (en) 2013-02-14
AU2009327322A1 (en) 2011-06-30
ZA201103724B (en) 2012-09-26
EP2367426A4 (en) 2012-05-02
JP2012512914A (ja) 2012-06-07
CA2747716A1 (en) 2010-06-24

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