EA201101463A1 - Растворы для гемодиализа и перитонеального диализа более чем с одним соединением креатина - Google Patents
Растворы для гемодиализа и перитонеального диализа более чем с одним соединением креатинаInfo
- Publication number
- EA201101463A1 EA201101463A1 EA201101463A EA201101463A EA201101463A1 EA 201101463 A1 EA201101463 A1 EA 201101463A1 EA 201101463 A EA201101463 A EA 201101463A EA 201101463 A EA201101463 A EA 201101463A EA 201101463 A1 EA201101463 A1 EA 201101463A1
- Authority
- EA
- Eurasian Patent Office
- Prior art keywords
- peritoneal dialysis
- solutions
- creatine
- hemodialysis
- dialysis
- Prior art date
Links
- CVSVTCORWBXHQV-UHFFFAOYSA-N creatine Chemical compound NC(=[NH2+])N(C)CC([O-])=O CVSVTCORWBXHQV-UHFFFAOYSA-N 0.000 title abstract 7
- 238000000502 dialysis Methods 0.000 title abstract 6
- 229960003624 creatine Drugs 0.000 title abstract 3
- 239000006046 creatine Substances 0.000 title abstract 3
- 238000001631 haemodialysis Methods 0.000 title abstract 3
- 230000000322 hemodialysis Effects 0.000 title abstract 3
- 239000000243 solution Substances 0.000 abstract 4
- 239000012141 concentrate Substances 0.000 abstract 3
- 239000013543 active substance Substances 0.000 abstract 2
- DDRJAANPRJIHGJ-UHFFFAOYSA-N creatinine Chemical compound CN1CC(=O)NC1=N DDRJAANPRJIHGJ-UHFFFAOYSA-N 0.000 abstract 2
- 238000000034 method Methods 0.000 abstract 2
- WQZGKKKJIJFFOK-GASJEMHNSA-N Glucose Natural products OC[C@H]1OC(O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-GASJEMHNSA-N 0.000 abstract 1
- 206010034665 Peritoneal fibrosis Diseases 0.000 abstract 1
- 208000001647 Renal Insufficiency Diseases 0.000 abstract 1
- 229940109239 creatinine Drugs 0.000 abstract 1
- 230000001419 dependent effect Effects 0.000 abstract 1
- 239000008103 glucose Substances 0.000 abstract 1
- 201000006370 kidney failure Diseases 0.000 abstract 1
- 210000000056 organ Anatomy 0.000 abstract 1
- 239000003330 peritoneal dialysis fluid Substances 0.000 abstract 1
- 208000001072 type 2 diabetes mellitus Diseases 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
- A61K31/197—Carboxylic acids, e.g. valproic acid having an amino group the amino and the carboxyl groups being attached to the same acyclic carbon chain, e.g. gamma-aminobutyric acid [GABA], beta-alanine, epsilon-aminocaproic acid or pantothenic acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
- A61K31/197—Carboxylic acids, e.g. valproic acid having an amino group the amino and the carboxyl groups being attached to the same acyclic carbon chain, e.g. gamma-aminobutyric acid [GABA], beta-alanine, epsilon-aminocaproic acid or pantothenic acid
- A61K31/198—Alpha-amino acids, e.g. alanine or edetic acid [EDTA]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/02—Inorganic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/08—Solutions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/12—Drugs for disorders of the urinary system of the kidneys
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Inorganic Chemistry (AREA)
- Biochemistry (AREA)
- Molecular Biology (AREA)
- Dermatology (AREA)
- Urology & Nephrology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- External Artificial Organs (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
Abstract
Изобретение связано с растворами для гемодиализа и перитонеального диализа и их концентратами, а также с использованием соединений креатина для подготовки раствора или концентрата диализа. Кроме того, настоящее изобретение ориентировано на методику подготовки растворов и концентратов для гемодиализа и перитонеального диализа с содержанием креатина и предназначено для лечения пациентов с почечной недостаточностью, зависящих от диализа, с целью повышения уровня креатинина в клетках и органах и улучшения их состояния в целом. И, наконец, настоящее изобретение ориентировано на методику лечения пациентов с помощью перитонеального диализа с применением растворов с высоким содержанием креатина, таких как осмотически активных веществ, по отдельности или в сочетании с другими осмотически активными веществами, чтобы значительно сократить концентрацию глюкозы в жидкости для перитонеального диализа, потому что она может привести к фиброзу брюшины и возникновению диабета II типа.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP09005038 | 2009-04-06 | ||
| PCT/CH2010/000065 WO2010115291A1 (en) | 2009-04-06 | 2010-03-10 | Hemodialysis and peritoneal dialysis solutions comprising one or more creatine compounds |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| EA201101463A1 true EA201101463A1 (ru) | 2012-03-30 |
| EA025137B1 EA025137B1 (ru) | 2016-11-30 |
Family
ID=42111284
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| EA201101463A EA025137B1 (ru) | 2009-04-06 | 2010-03-10 | Раствор для диализа, включающий одно или более соединений креатина и способ его получения |
Country Status (14)
| Country | Link |
|---|---|
| US (2) | US9248112B2 (ru) |
| EP (1) | EP2416770B1 (ru) |
| JP (1) | JP6130666B2 (ru) |
| CN (1) | CN102421431B (ru) |
| AU (1) | AU2010234206B2 (ru) |
| BR (1) | BRPI1006260B8 (ru) |
| CA (1) | CA2757327C (ru) |
| EA (1) | EA025137B1 (ru) |
| ES (1) | ES2615204T3 (ru) |
| HK (1) | HK1164157A1 (ru) |
| IL (1) | IL215504A (ru) |
| PL (1) | PL2416770T3 (ru) |
| WO (1) | WO2010115291A1 (ru) |
| ZA (1) | ZA201107715B (ru) |
Families Citing this family (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| BR112012001320B1 (pt) * | 2009-07-24 | 2021-10-05 | Crearene Ag | Solução de diálise, kit configurado para preparação de uma solução de diálise e preparação sólida |
| ES2382513B2 (es) * | 2012-05-07 | 2012-09-24 | Luiz Guilherme STARK AROEIRA | Solución de diálisis que contiene al menos un antagonista de CCR2 |
| CN102973599B (zh) * | 2012-12-13 | 2014-04-23 | 天津金耀集团有限公司 | 腹膜透析液（乳酸盐）组合物 |
| US11077238B2 (en) | 2013-06-07 | 2021-08-03 | Allena Pharmaceuticals, Inc. | Compositions, methods, and devices for dialysis |
| WO2017084682A1 (en) | 2015-11-20 | 2017-05-26 | Hepa Wash Gmbh | Method for extracorporeal carbon dioxide removal |
| WO2017084683A1 (en) | 2015-11-20 | 2017-05-26 | Hepa Wash Gmbh | Method for extracorporeal lung support |
| PL3429657T3 (pl) | 2016-03-14 | 2022-08-22 | Advitos Gmbh | Systemy albo aparatury dla przeprowadzania dializy |
| MX2019001360A (es) * | 2016-08-11 | 2019-06-03 | Cellix Bio Private Ltd | Composiciones y metodos para el tratamiento de sindrome de intestino irritable. |
| US20210100941A1 (en) * | 2017-03-28 | 2021-04-08 | Advitos Gmbh | Compositions and methods for regenerating carrier protein-containing multiple pass albumin dialysis fluid |
| JP7213556B2 (ja) | 2017-05-22 | 2023-01-27 | アドビトス ゲーエムベーハー | 二酸化炭素を除去するための方法およびシステム |
| EP3697424A4 (en) * | 2017-10-20 | 2021-07-07 | University of Georgia Research Foundation, Inc. | SURFACES AND COATING COMPOSITIONS WITH ANTI-FOULING, ANTITHROMBOTIC AND ANTIBACTERIAL PROPERTIES AND THEIR PREPARATION METHODS |
| CN107890568A (zh) * | 2017-10-31 | 2018-04-10 | 华仁药业股份有限公司 | 一种低危害的血液滤过置换液及其制备工艺 |
| KR101864384B1 (ko) * | 2017-12-11 | 2018-06-04 | (주)나노스템 | 콜린 알포세레이트를 유효성분으로 하는 쥐남의 치료, 개선 또는 예방용 조성물 및 방법 |
| GB201801633D0 (en) * | 2018-02-01 | 2018-03-21 | Ogorman Edward | Sports supplements based on liquid creatine |
| MX2021003653A (es) | 2018-10-11 | 2021-06-23 | Sanifit Therapeutics S A | Inositol fosfatos para el tratamiento de calcificacion ectopica. |
| CN114903998A (zh) * | 2021-02-07 | 2022-08-16 | 大连医科大学附属第二医院 | 渗透压保护防治腹膜纤维化和超滤衰竭 |
Family Cites Families (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4604379A (en) * | 1984-06-18 | 1986-08-05 | Curators Of The University Of Missouri | Dialysis solutions containing cross-linked gelatin |
| FR2614219B1 (fr) * | 1987-04-23 | 1993-07-09 | Materiels Annexes Dialyse | Procede de fabrication de granules destines a la preparation de solutions de dialyse et installation pour sa mise en oeuvre. |
| US5827820A (en) * | 1992-04-06 | 1998-10-27 | Baxter International Inc. | Aqueous peritoneal dialysis solution |
| ATE332127T1 (de) | 1994-11-08 | 2006-07-15 | Avicena Group Inc | Verwendung von kreatin oder kreatinanologen zur behandlung von huntington chorea, morbus parkinson und amyotrophen lateralsklerose |
| DE69628025T2 (de) | 1995-10-11 | 2004-04-01 | Avicena Group, Inc., Cambridge | Verwendung von kreatinanalogen zur behandlung von störungen des glukosemetabolismus |
| WO2000068412A1 (fr) * | 1999-05-11 | 2000-11-16 | Wakenyaku Co., Ltd. | Preparation contenant un extrait de cellules pour la synthese d'une proteine exempte de cellules, et moyen de synthese d'une proteine exempte de cellules |
| WO2001000212A1 (en) | 1999-06-25 | 2001-01-04 | Avicena Group, Inc. | Use of creatine or creatine analogs for the prevention and treatment of transmissible spongiform encephalopathies |
| US6242491B1 (en) | 1999-06-25 | 2001-06-05 | Rima Kaddurah-Daouk | Use of creatine or creatine compounds for skin preservation |
| US20030013767A1 (en) * | 2001-07-13 | 2003-01-16 | Samuel Bessman | Method of treating weight loss using creatine |
| AU2003238872A1 (en) | 2002-06-04 | 2003-12-19 | Avicena Group, Inc. | Methods of treating cognitive dysfunction by modulating brain energy metabolism |
| US20070292403A1 (en) | 2006-05-11 | 2007-12-20 | Avicena Group, Inc. | Methods of treating a neurological disorder with creatine monohydrate |
| US20080003208A1 (en) | 2006-05-11 | 2008-01-03 | Avicena Froup, Inc. | Creatine-ligand compounds and methods of use thereof |
| DE102006050931A1 (de) * | 2006-10-28 | 2008-04-30 | Alzchem Trostberg Gmbh | Feste oder wässrige alkalische Zubereitung auf Basis einer Kreatin-Komponente, Verfahren zu deren Herstellung und ihre Verwendung |
| AU2007332800A1 (en) | 2006-12-07 | 2008-06-19 | Avicena Group, Inc. | Creatine compositions for skin treatment |
| US20090005450A1 (en) | 2007-04-09 | 2009-01-01 | Belinda Tsao Nivaggioli | Use of creatine compounds for the treatment of eye disorders |
| US20090098221A1 (en) | 2007-05-03 | 2009-04-16 | Belinda Tsao Nivaggioli | Creatine ascorbyl derivatives and methods of use thereof |
| WO2009002913A1 (en) | 2007-06-22 | 2008-12-31 | Avicena Group, Inc. | Use of creatine compounds to treat dermatitis |
-
2010
- 2010-03-10 EP EP10707804.0A patent/EP2416770B1/en active Active
- 2010-03-10 CA CA2757327A patent/CA2757327C/en active Active
- 2010-03-10 AU AU2010234206A patent/AU2010234206B2/en active Active
- 2010-03-10 BR BRPI1006260A patent/BRPI1006260B8/pt active IP Right Grant
- 2010-03-10 US US13/263,189 patent/US9248112B2/en active Active
- 2010-03-10 PL PL10707804T patent/PL2416770T3/pl unknown
- 2010-03-10 JP JP2012503842A patent/JP6130666B2/ja active Active
- 2010-03-10 EA EA201101463A patent/EA025137B1/ru not_active IP Right Cessation
- 2010-03-10 ES ES10707804.0T patent/ES2615204T3/es active Active
- 2010-03-10 WO PCT/CH2010/000065 patent/WO2010115291A1/en active Application Filing
- 2010-03-10 CN CN201080018482.3A patent/CN102421431B/zh active Active
-
2011
- 2011-10-03 IL IL215504A patent/IL215504A/en active IP Right Grant
- 2011-10-21 ZA ZA2011/07715A patent/ZA201107715B/en unknown
-
2012
- 2012-05-24 HK HK12105122.6A patent/HK1164157A1/zh unknown
-
2016
- 2016-01-11 US US14/993,079 patent/US20160120829A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| AU2010234206A1 (en) | 2011-11-03 |
| AU2010234206A2 (en) | 2011-11-10 |
| EP2416770B1 (en) | 2016-10-26 |
| JP2012522812A (ja) | 2012-09-27 |
| US20160120829A1 (en) | 2016-05-05 |
| CA2757327A1 (en) | 2010-10-14 |
| ES2615204T3 (es) | 2017-06-05 |
| EP2416770A1 (en) | 2012-02-15 |
| IL215504A (en) | 2017-04-30 |
| CN102421431A (zh) | 2012-04-18 |
| HK1164157A1 (zh) | 2012-09-21 |
| US20120101069A1 (en) | 2012-04-26 |
| CA2757327C (en) | 2017-12-12 |
| ZA201107715B (en) | 2012-07-25 |
| WO2010115291A1 (en) | 2010-10-14 |
| BRPI1006260B1 (pt) | 2020-11-17 |
| JP6130666B2 (ja) | 2017-05-17 |
| US9248112B2 (en) | 2016-02-02 |
| BRPI1006260B8 (pt) | 2021-05-25 |
| BRPI1006260A2 (pt) | 2017-01-17 |
| PL2416770T3 (pl) | 2017-06-30 |
| EA025137B1 (ru) | 2016-11-30 |
| AU2010234206B2 (en) | 2016-10-27 |
| IL215504A0 (en) | 2011-12-29 |
| CN102421431B (zh) | 2019-04-02 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| MM4A | Lapse of a eurasian patent due to non-payment of renewal fees within the time limit in the following designated state(s) |
Designated state(s): AM KG MD TJ |
|
| PC4A | Registration of transfer of a eurasian patent by assignment |