EA201071120A1 - Способ получения гетероарилбензопроизводных сульфаматов и кристаллической формы n-((2s)-6-хлор-2,3-дигидро-l,4-бензодиоксин-2-ил)метилсульфамида - Google Patents
Способ получения гетероарилбензопроизводных сульфаматов и кристаллической формы n-((2s)-6-хлор-2,3-дигидро-l,4-бензодиоксин-2-ил)метилсульфамидаInfo
- Publication number
- EA201071120A1 EA201071120A1 EA201071120A EA201071120A EA201071120A1 EA 201071120 A1 EA201071120 A1 EA 201071120A1 EA 201071120 A EA201071120 A EA 201071120A EA 201071120 A EA201071120 A EA 201071120A EA 201071120 A1 EA201071120 A1 EA 201071120A1
- Authority
- EA
- Eurasian Patent Office
- Prior art keywords
- sulfamates
- obtaining
- derivatives
- heteroarilbenze
- digydro
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D319/00—Heterocyclic compounds containing six-membered rings having two oxygen atoms as the only ring hetero atoms
- C07D319/10—1,4-Dioxanes; Hydrogenated 1,4-dioxanes
- C07D319/14—1,4-Dioxanes; Hydrogenated 1,4-dioxanes condensed with carbocyclic rings or ring systems
- C07D319/16—1,4-Dioxanes; Hydrogenated 1,4-dioxanes condensed with carbocyclic rings or ring systems condensed with one six-membered ring
- C07D319/20—1,4-Dioxanes; Hydrogenated 1,4-dioxanes condensed with carbocyclic rings or ring systems condensed with one six-membered ring with substituents attached to the hetero ring
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
- C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
- C07D311/58—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring other than with oxygen or sulphur atoms in position 2 or 4
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D317/00—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
- C07D317/08—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
- C07D317/44—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D317/46—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems condensed with one six-membered ring
- C07D317/48—Methylenedioxybenzenes or hydrogenated methylenedioxybenzenes, unsubstituted on the hetero ring
- C07D317/50—Methylenedioxybenzenes or hydrogenated methylenedioxybenzenes, unsubstituted on the hetero ring with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to atoms of the carbocyclic ring
- C07D317/58—Radicals substituted by nitrogen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D321/00—Heterocyclic compounds containing rings having two oxygen atoms as the only ring hetero atoms, not provided for by groups C07D317/00 - C07D319/00
- C07D321/02—Seven-membered rings
- C07D321/04—Seven-membered rings not condensed with other rings
- C07D321/08—1,4-Dioxepines; Hydrogenated 1,4-dioxepines
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| PCT/US2008/058233 WO2009120191A1 (en) | 2008-03-26 | 2008-03-26 | Process for the preparation of benzo-fused heteroaryl sulfamates and crystalline form of n- ( ( (2s) -6-chloro-2,3-dihydro-l,4-benzodioxin-2-yl) methyl-sulfamide |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| EA201071120A1 true EA201071120A1 (ru) | 2011-06-30 |
Family
ID=40030223
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| EA201071120A EA201071120A1 (ru) | 2008-03-26 | 2008-03-26 | Способ получения гетероарилбензопроизводных сульфаматов и кристаллической формы n-((2s)-6-хлор-2,3-дигидро-l,4-бензодиоксин-2-ил)метилсульфамида |
Country Status (14)
| Country | Link |
|---|---|
| EP (1) | EP2280950A1 (es) |
| JP (1) | JP2011515464A (es) |
| KR (1) | KR20100126535A (es) |
| CN (1) | CN101981019A (es) |
| AU (1) | AU2008353491A1 (es) |
| BR (1) | BRPI0822454A2 (es) |
| CA (1) | CA2719624A1 (es) |
| CR (1) | CR11761A (es) |
| EA (1) | EA201071120A1 (es) |
| EC (1) | ECSP10010499A (es) |
| IL (1) | IL208222A0 (es) |
| MX (1) | MX2010010595A (es) |
| WO (1) | WO2009120191A1 (es) |
| ZA (1) | ZA201007611B (es) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| MY147767A (en) | 2004-06-16 | 2013-01-31 | Janssen Pharmaceutica Nv | Novel sulfamate and sulfamide derivatives useful for the treatment of epilepsy and related disorders |
| WO2006127184A1 (en) | 2005-05-20 | 2006-11-30 | Janssen Pharmaceutica N.V. | Process for preparation of sulfamide derivatives |
| US8937096B2 (en) | 2005-12-19 | 2015-01-20 | Janssen Pharmaceutica Nv | Use of benzo-fused heterocyle sulfamide derivatives for the treatment of mania and bipolar disorder |
| US8497298B2 (en) | 2005-12-19 | 2013-07-30 | Janssen Pharmaceutica Nv | Use of benzo-fused heterocycle sulfamide derivatives for lowering lipids and lowering blood glucose levels |
| US8691867B2 (en) | 2005-12-19 | 2014-04-08 | Janssen Pharmaceutica Nv | Use of benzo-fused heterocycle sulfamide derivatives for the treatment of substance abuse and addiction |
| AU2007253814A1 (en) | 2006-05-19 | 2007-11-29 | Janssen Pharmaceutica N.V. | Co-therapy for the treatment of epilepsy |
| AU2009271362B2 (en) * | 2008-06-23 | 2014-03-13 | Janssen Pharmaceutica Nv | Crystalline form of (2s)-(-)-N-(6-chloro-2,3-dihydro-benzo[1,4]dioxin-2-ylmethyl)-sulfamide |
| US8815939B2 (en) | 2008-07-22 | 2014-08-26 | Janssen Pharmaceutica Nv | Substituted sulfamide derivatives |
| CN107954906B (zh) * | 2017-11-24 | 2020-10-16 | 西北师范大学 | 一种芳基磺酰叔胺类化合物的合成方法 |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4513006A (en) * | 1983-09-26 | 1985-04-23 | Mcneil Lab., Inc. | Anticonvulsant sulfamate derivatives |
| TW200612905A (en) * | 2004-06-16 | 2006-05-01 | Janssen Pharmaceutica Nv | Novel sulfamate and sulfamide derivatives useful for the treatment of epilepsy and related disorders |
| MY147767A (en) * | 2004-06-16 | 2013-01-31 | Janssen Pharmaceutica Nv | Novel sulfamate and sulfamide derivatives useful for the treatment of epilepsy and related disorders |
| AU2005277134A1 (en) * | 2004-08-24 | 2006-03-02 | Janssen Pharmaceutica N.V. | Novel benzo-fused heteroaryl sulfamide derivatives useful as anticonvulsant agents |
| TW200738669A (en) * | 2006-02-22 | 2007-10-16 | Janssen Pharmaceutica Nv | Crystalline forms of N-(benzo[b]thien-3-ylmethyl)-sulfamide |
-
2008
- 2008-03-26 EA EA201071120A patent/EA201071120A1/ru unknown
- 2008-03-26 CN CN2008801285434A patent/CN101981019A/zh active Pending
- 2008-03-26 CA CA2719624A patent/CA2719624A1/en not_active Abandoned
- 2008-03-26 KR KR1020107023447A patent/KR20100126535A/ko not_active Application Discontinuation
- 2008-03-26 WO PCT/US2008/058233 patent/WO2009120191A1/en active Application Filing
- 2008-03-26 JP JP2011501761A patent/JP2011515464A/ja not_active Withdrawn
- 2008-03-26 AU AU2008353491A patent/AU2008353491A1/en not_active Abandoned
- 2008-03-26 BR BRPI0822454-4A patent/BRPI0822454A2/pt not_active IP Right Cessation
- 2008-03-26 MX MX2010010595A patent/MX2010010595A/es unknown
- 2008-03-26 EP EP08744381A patent/EP2280950A1/en not_active Withdrawn
-
2010
- 2010-09-19 IL IL208222A patent/IL208222A0/en unknown
- 2010-09-24 EC EC2010010499A patent/ECSP10010499A/es unknown
- 2010-10-25 ZA ZA2010/07611A patent/ZA201007611B/en unknown
- 2010-10-26 CR CR11761A patent/CR11761A/es not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| CR11761A (es) | 2011-07-06 |
| ECSP10010499A (es) | 2010-10-30 |
| IL208222A0 (en) | 2010-12-30 |
| KR20100126535A (ko) | 2010-12-01 |
| CA2719624A1 (en) | 2009-10-01 |
| EP2280950A1 (en) | 2011-02-09 |
| BRPI0822454A2 (pt) | 2015-06-16 |
| JP2011515464A (ja) | 2011-05-19 |
| WO2009120191A1 (en) | 2009-10-01 |
| ZA201007611B (en) | 2012-04-25 |
| CN101981019A (zh) | 2011-02-23 |
| MX2010010595A (es) | 2010-10-25 |
| AU2008353491A1 (en) | 2009-10-01 |
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