EA201070914A1 - Применение ранолазина для лечения боли - Google Patents

Применение ранолазина для лечения боли

Info

Publication number
EA201070914A1
EA201070914A1 EA201070914A EA201070914A EA201070914A1 EA 201070914 A1 EA201070914 A1 EA 201070914A1 EA 201070914 A EA201070914 A EA 201070914A EA 201070914 A EA201070914 A EA 201070914A EA 201070914 A1 EA201070914 A1 EA 201070914A1
Authority
EA
Eurasian Patent Office
Prior art keywords
ranolazine
pain
treatment
application
patient
Prior art date
Application number
EA201070914A
Other languages
English (en)
Inventor
Иван Даймонд
Луис Белардинелли
Джон Шриок
Сридхаран Раджамани
Original Assignee
Гайлид Сайэнсиз, Инк.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Гайлид Сайэнсиз, Инк. filed Critical Гайлид Сайэнсиз, Инк.
Publication of EA201070914A1 publication Critical patent/EA201070914A1/ru

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P23/00—Anaesthetics
    • A61P23/02—Local anaesthetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]

Landscapes

  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Anesthesiology (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Engineering & Computer Science (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

Данное изобретение относится к способам лечения пациента, страдающего невропатической или ноцицептивной болью, которая может быть механической, висцеральной и/или воспалительной по природе, включающим введение терапевтически эффективного количества ранолазина нуждающемуся в этом пациенту.
EA201070914A 2008-02-06 2009-02-06 Применение ранолазина для лечения боли EA201070914A1 (ru)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US2669908P 2008-02-06 2008-02-06
US5743708P 2008-05-30 2008-05-30
PCT/US2009/033464 WO2009100380A1 (en) 2008-02-06 2009-02-06 Use of ranolazine for treating pain

Publications (1)

Publication Number Publication Date
EA201070914A1 true EA201070914A1 (ru) 2011-04-29

Family

ID=40548472

Family Applications (1)

Application Number Title Priority Date Filing Date
EA201070914A EA201070914A1 (ru) 2008-02-06 2009-02-06 Применение ранолазина для лечения боли

Country Status (13)

Country Link
US (1) US20090203707A1 (ru)
EP (1) EP2252294A1 (ru)
KR (1) KR20110013348A (ru)
CN (1) CN101977605A (ru)
AU (1) AU2009212254A1 (ru)
BR (1) BRPI0908428A2 (ru)
CA (1) CA2713521A1 (ru)
CO (1) CO6290663A2 (ru)
EA (1) EA201070914A1 (ru)
EC (1) ECSP10010446A (ru)
IL (1) IL207292A0 (ru)
MA (1) MA32132B1 (ru)
WO (1) WO2009100380A1 (ru)

Families Citing this family (21)

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Publication number Priority date Publication date Assignee Title
US8822473B2 (en) * 2002-05-21 2014-09-02 Gilead Sciences, Inc. Method of treating diabetes
EP2332540A1 (en) * 2002-05-21 2011-06-15 Cv Therapeutics, Inc. Administration of ranolazine for the treatment of diabetes
US20090247535A1 (en) * 2008-03-26 2009-10-01 Duke University Use of ranolazine for non-cardiovascular disorders
JP2012526848A (ja) * 2009-05-14 2012-11-01 ギリアード サイエンシーズ， インコーポレイテッド Ｃｎｓ障害の治療のためのラノラジン
CA2774715C (en) 2009-07-27 2018-04-03 Gilead Sciences, Inc. Fused heterocyclic compounds as ion channel modulators
CN103096977B (zh) 2010-07-02 2017-02-15 吉利德科学公司 作为离子通道调节剂的稠杂环化合物
CA2834164A1 (en) 2011-05-10 2012-11-15 Gilead Sciences, Inc. Fused benzoxazinones as ion channel modulators
NO3175985T3 (ru) 2011-07-01 2018-04-28
TWI478908B (zh) 2011-07-01 2015-04-01 Gilead Sciences Inc 作為離子通道調節劑之稠合雜環化合物
SG11201604457XA (en) 2013-12-19 2016-07-28 Gilead Sciences Inc Fused heterocyclic compounds as ion channel modulators
CA3016081A1 (en) 2016-03-04 2017-09-08 Gilead Sciences, Inc. Compositions and combinations of autotaxin inhibitors
JP7105797B2 (ja) 2016-11-28 2022-07-25 プラクシス プレシジョン メディシンズ， インコーポレイテッド 化合物及びその使用方法
WO2018098491A1 (en) 2016-11-28 2018-05-31 Praxis Precision Medicines, Inc. Compounds and their methods of use
WO2018148745A1 (en) 2017-02-13 2018-08-16 Praxis Precision Medicines , Inc. Compounds and their methods of use
US11731966B2 (en) 2017-04-04 2023-08-22 Praxis Precision Medicines, Inc. Compounds and their methods of use
WO2019035951A1 (en) 2017-08-15 2019-02-21 Praxis Precision Medicines, Inc. COMPOUNDS AND THEIR METHODS OF USE
MX2020012838A (es) 2018-05-30 2021-07-16 Praxis Prec Medicines Inc Moduladores de los canales ionicos.
US11773099B2 (en) 2019-05-28 2023-10-03 Praxis Precision Medicines, Inc. Compounds and their methods of use
US11279700B2 (en) 2019-05-31 2022-03-22 Praxis Precision Medicines, Inc. Ion channel modulators
US11505554B2 (en) 2019-05-31 2022-11-22 Praxis Precision Medicines, Inc. Substituted pyridines as ion channel modulators
MX2022006452A (es) 2019-11-27 2022-07-11 Praxis Prec Medicines Inc Formulaciones de moduladores de canales ionicos y metodos de preparacion y uso de moduladores de canales ionicos.

Family Cites Families (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4657264A (en) * 1985-11-01 1987-04-14 Ingersoll-Rand Company Fluid seal assembly with segmented sub-assembly
ATE223218T1 (de) * 1989-06-23 2002-09-15 Syntex Llc Ranolazin und verwandte piperazine zum schutz der skelettmuskulatur
US5455045A (en) * 1993-05-13 1995-10-03 Syntex (U.S.A.) Inc. High dose formulations
US6303607B1 (en) * 1998-09-10 2001-10-16 Cv Therapeutics, Inc. Method for administering a sustained release ranolanolazine formulation
US6479496B1 (en) * 1998-09-10 2002-11-12 Cv Therapeutics, Inc. Methods for treating angina with ranolazine
JP2004505886A (ja) * 2000-02-18 2004-02-26 スィーヴィー　セラピューティクス　インコーポレイテッド 鬱血性心不全の処置における部分的な脂肪酸酸化阻害剤
US20030220344A1 (en) * 2002-04-04 2003-11-27 Luiz Belardinelli Method of treating arrhythmias
US8822473B2 (en) * 2002-05-21 2014-09-02 Gilead Sciences, Inc. Method of treating diabetes
EP2332540A1 (en) * 2002-05-21 2011-06-15 Cv Therapeutics, Inc. Administration of ranolazine for the treatment of diabetes
CN101098682A (zh) * 2005-01-06 2008-01-02 Cv医药有限公司 包括雷诺嗪的缓释药物制剂
JP2009516751A (ja) * 2005-11-21 2009-04-23 ザ・ボード・オブ・トラスティーズ・オブ・ザ・ユニバーシティー・オブ・アラバマ・フォー・アンド・オン・ビハーフ・オブ・ザ・ユニバーシティー・オブ・アラバマ 神経保護のための小分子化合物を使用する方法
CA2653056A1 (en) * 2006-07-27 2008-01-31 Cv Therapeutics, Inc. Aldh-2 inhibitors in the treatment of addiction
WO2008101008A1 (en) * 2007-02-13 2008-08-21 Cv Therapeutics, Inc. Use of ranolazine for the treatment of coronary microvascular diseases
US20080214555A1 (en) * 2007-02-13 2008-09-04 Markus Jerling Use of ranolazine for the treatment of cardiovascular diseases
US7951813B2 (en) * 2007-04-05 2011-05-31 Gilead Sciences, Inc. Quinazolinone derivatives as ALDH-2 inhibitors
AU2008240202A1 (en) * 2007-04-12 2008-10-23 Cv Therapeutics, Inc. Ranolazine for enhancing insulin secretion
AU2008323953A1 (en) * 2007-11-06 2009-05-14 Gilead Palo Alto, Inc. ALDH-2 inhibitors in the treatment of psychiatric disorders

Also Published As

Publication number Publication date
BRPI0908428A2 (pt) 2015-12-08
AU2009212254A1 (en) 2009-08-13
MA32132B1 (fr) 2011-03-01
KR20110013348A (ko) 2011-02-09
CN101977605A (zh) 2011-02-16
ECSP10010446A (es) 2010-10-30
WO2009100380A1 (en) 2009-08-13
US20090203707A1 (en) 2009-08-13
CO6290663A2 (es) 2011-06-20
IL207292A0 (en) 2010-12-30
CA2713521A1 (en) 2009-08-13
EP2252294A1 (en) 2010-11-24

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