EA201001363A1 - Комбинация, содержащая соединение, которое связывает каннабиноидный рецептор, и опиоид - Google Patents

Комбинация, содержащая соединение, которое связывает каннабиноидный рецептор, и опиоид

Info

Publication number
EA201001363A1
EA201001363A1 EA201001363A EA201001363A EA201001363A1 EA 201001363 A1 EA201001363 A1 EA 201001363A1 EA 201001363 A EA201001363 A EA 201001363A EA 201001363 A EA201001363 A EA 201001363A EA 201001363 A1 EA201001363 A1 EA 201001363A1
Authority
EA
Eurasian Patent Office
Prior art keywords
cannabinoid receptor
opioid
binds
connection
combination containing
Prior art date
Application number
EA201001363A
Other languages
English (en)
Russian (ru)
Inventor
Доналд Джонс
Томас Джордж Эванс
Original Assignee
Новартис Аг
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Новартис Аг filed Critical Новартис Аг
Publication of EA201001363A1 publication Critical patent/EA201001363A1/ru

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/01—Hydrocarbons
    • A61K31/015—Hydrocarbons carbocyclic
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/12—Ketones
    • A61K31/121—Ketones acyclic
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A61K31/137—Arylalkylamines, e.g. amphetamine, epinephrine, salbutamol, ephedrine or methadone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445—Non condensed piperidines, e.g. piperocaine
    • A61K31/4468—Non condensed piperidines, e.g. piperocaine having a nitrogen directly attached in position 4, e.g. clebopride, fentanyl
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A61K31/485—Morphinan derivatives, e.g. morphine, codeine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Emergency Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Pain & Pain Management (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
EA201001363A 2008-02-28 2009-02-26 Комбинация, содержащая соединение, которое связывает каннабиноидный рецептор, и опиоид EA201001363A1 (ru)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP08152104 2008-02-28
PCT/EP2009/052297 WO2009106574A2 (en) 2008-02-28 2009-02-26 Combinations for treating hiv-associated pain

Publications (1)

Publication Number Publication Date
EA201001363A1 true EA201001363A1 (ru) 2011-04-29

Family

ID=39415383

Family Applications (1)

Application Number Title Priority Date Filing Date
EA201001363A EA201001363A1 (ru) 2008-02-28 2009-02-26 Комбинация, содержащая соединение, которое связывает каннабиноидный рецептор, и опиоид

Country Status (11)

Country Link
US (1) US20090281194A1 (https=)
EP (1) EP2257281A2 (https=)
JP (1) JP2011513278A (https=)
KR (1) KR20100126441A (https=)
CN (1) CN101945650A (https=)
AU (1) AU2009218456A1 (https=)
BR (1) BRPI0907805A2 (https=)
CA (1) CA2716405A1 (https=)
EA (1) EA201001363A1 (https=)
MX (1) MX2010009507A (https=)
WO (1) WO2009106574A2 (https=)

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2222770B (en) * 1988-09-16 1992-07-29 Sandoz Ltd Pharmaceutical compositions containing cyclosporins
GB0012795D0 (en) * 2000-05-25 2000-07-19 Novartis Ag Organic compounds
GB0028702D0 (en) * 2000-11-24 2001-01-10 Novartis Ag Organic compounds
US8449908B2 (en) * 2000-12-22 2013-05-28 Alltranz, Llc Transdermal delivery of cannabidiol
GB0504950D0 (en) * 2005-03-10 2005-04-20 Novartis Ag Organic compositions
US20090029984A1 (en) * 2005-07-11 2009-01-29 N.V. Organon Synergistic combination for the treatment of pain (cannabinoid receptor agonist and opioid receptor agonist)

Also Published As

Publication number Publication date
MX2010009507A (es) 2010-09-24
AU2009218456A1 (en) 2009-09-03
JP2011513278A (ja) 2011-04-28
BRPI0907805A2 (pt) 2015-07-14
WO2009106574A2 (en) 2009-09-03
CN101945650A (zh) 2011-01-12
WO2009106574A3 (en) 2009-12-17
CA2716405A1 (en) 2009-09-03
US20090281194A1 (en) 2009-11-12
EP2257281A2 (en) 2010-12-08
KR20100126441A (ko) 2010-12-01

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