EA201000501A1 - Фармацевтическая композиция, содержащая не обладающий нейротоксичностью активатор плазминоген для лечения удара - Google Patents

Фармацевтическая композиция, содержащая не обладающий нейротоксичностью активатор плазминоген для лечения удара

Info

Publication number
EA201000501A1
EA201000501A1 EA201000501A EA201000501A EA201000501A1 EA 201000501 A1 EA201000501 A1 EA 201000501A1 EA 201000501 A EA201000501 A EA 201000501A EA 201000501 A EA201000501 A EA 201000501A EA 201000501 A1 EA201000501 A1 EA 201000501A1
Authority
EA
Eurasian Patent Office
Prior art keywords
pharmaceutical composition
plasminogen activator
neuroquatic
presenting
treatment
Prior art date
Application number
EA201000501A
Other languages
English (en)
Inventor
Мариола Зенген
Вольфганг Зенген
Вольф-Дитер Шлойнинг
Роберт Медкаф
Original Assignee
Пайон Дойчланд Гмбх
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Пайон Дойчланд Гмбх filed Critical Пайон Дойчланд Гмбх
Publication of EA201000501A1 publication Critical patent/EA201000501A1/ru

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43—Enzymes; Proenzymes; Derivatives thereof
    • A61K38/46—Hydrolases (3)
    • A61K38/48—Hydrolases (3) acting on peptide bonds (3.4)
    • A61K38/49—Urokinase; Tissue plasminogen activator
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/55—Protease inhibitors
    • A61K38/57—Protease inhibitors from animals; from humans
    • A61K38/58—Protease inhibitors from animals; from humans from leeches, e.g. hirudin, eglin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Abstract

Изобретение относится к фармацевтической композиции, содержащей активатор плазминогена из слюны Desmodus rotundus (DSPA) альфа 1, для терапевтического лечения удара у людей. Фармацевтическая композиция содержит от 60 до 230 мкг/кг DSPA альфа 1 и предназначена для применения в виде капельной инфузии и болюсной инъекции.
EA201000501A 2003-05-02 2004-04-30 Фармацевтическая композиция, содержащая не обладающий нейротоксичностью активатор плазминоген для лечения удара EA201000501A1 (ru)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EPPCT/EP2003/004608 2003-05-02
PCT/EP2003/004729 WO2004096267A1 (de) 2003-05-02 2003-05-06 Intravenöse injektion nicht-neurotoxischer plasminogen-aktivatoren zur behandlung von schlaganfall

Publications (1)

Publication Number Publication Date
EA201000501A1 true EA201000501A1 (ru) 2010-10-29

Family

ID=33395696

Family Applications (2)

Application Number Title Priority Date Filing Date
EA200501733A EA013837B1 (ru) 2003-05-02 2004-04-30 СПОСОБ ЛЕЧЕНИЯ УДАРА, ВКЛЮЧАЮЩИЙ ВВЕДЕНИЕ ЧЕЛОВЕКУ АКТИВАТОРА ПЛАЗМИНОГЕНА α1 ИЗ DESMODUS ROTUNDUS
EA201000501A EA201000501A1 (ru) 2003-05-02 2004-04-30 Фармацевтическая композиция, содержащая не обладающий нейротоксичностью активатор плазминоген для лечения удара

Family Applications Before (1)

Application Number Title Priority Date Filing Date
EA200501733A EA013837B1 (ru) 2003-05-02 2004-04-30 СПОСОБ ЛЕЧЕНИЯ УДАРА, ВКЛЮЧАЮЩИЙ ВВЕДЕНИЕ ЧЕЛОВЕКУ АКТИВАТОРА ПЛАЗМИНОГЕНА α1 ИЗ DESMODUS ROTUNDUS

Country Status (14)

Country Link
JP (1) JP2012077090A (ru)
CN (1) CN1849133B (ru)
AU (3) AU2003227721A1 (ru)
CY (1) CY1114254T1 (ru)
DK (1) DK1622639T3 (ru)
EA (2) EA013837B1 (ru)
ES (1) ES2401782T3 (ru)
HK (1) HK1092045A1 (ru)
IL (1) IL171636A (ru)
MY (1) MY151447A (ru)
PT (1) PT1622639E (ru)
SI (1) SI1622639T1 (ru)
WO (1) WO2004096267A1 (ru)
ZA (2) ZA200509053B (ru)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE10153601A1 (de) 2001-11-02 2003-05-22 Paion Gmbh DSPA zur Behandlung von Schlaganfall
TWI445540B (zh) 2007-04-20 2014-07-21 Ajinomoto Kk 抗低體溫組成物
AR067345A1 (es) * 2007-07-10 2009-10-07 Paion Deutschland Gmbh Uso de trombomodulina para la preparacion de un medicamento trombolitico
EP2014296A1 (en) * 2007-07-10 2009-01-14 PAION Deutschland GmbH Novel strategies for increasing the reperfusion in obstructed blood vessel

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FI100403B (fi) * 1988-07-20 1997-11-28 Schering Ag Menetelmä glykosyloitujen tai glykosyloimattomien vampyyrilepakon sylj en plasminogeeniaktivaattoreiden valmistamiseksi
NL8902454A (nl) * 1989-10-03 1991-05-01 Stichting Centraal Lab Mutanten van de humane plasminogeen activator inhibitor 1 (pai-1), hun bereiding en toepassing, en recombinante polynucleotiden die voor deze mutanten coderende genetische informatie omvatten.
AU672584B2 (en) * 1991-09-05 1996-10-10 Schering Aktiengesellschaft Collagen-induced platelet aggregation inhibitor
DE10153601A1 (de) * 2001-11-02 2003-05-22 Paion Gmbh DSPA zur Behandlung von Schlaganfall

Also Published As

Publication number Publication date
ZA200703704B (en) 2008-08-27
AU2004233601B2 (en) 2009-11-26
SI1622639T1 (sl) 2013-05-31
CN1849133B (zh) 2011-03-30
AU2010200718A1 (en) 2010-03-18
MY151447A (en) 2014-05-30
AU2003227721A1 (en) 2004-11-23
CN1849133A (zh) 2006-10-18
IL171636A (en) 2013-07-31
CY1114254T1 (el) 2016-08-31
PT1622639E (pt) 2013-04-01
DK1622639T3 (da) 2013-04-15
HK1092045A1 (en) 2007-02-02
WO2004096267A1 (de) 2004-11-11
ES2401782T3 (es) 2013-04-24
AU2004233601A1 (en) 2004-11-11
EA013837B1 (ru) 2010-08-30
EA200501733A1 (ru) 2006-06-30
JP2012077090A (ja) 2012-04-19
ZA200509053B (en) 2007-11-28

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