EA200970345A1 - Лечение гипербилирубинемии новорожденных с использованием низких дозировок станнсопорфина - Google Patents

Лечение гипербилирубинемии новорожденных с использованием низких дозировок станнсопорфина

Info

Publication number
EA200970345A1
EA200970345A1 EA200970345A EA200970345A EA200970345A1 EA 200970345 A1 EA200970345 A1 EA 200970345A1 EA 200970345 A EA200970345 A EA 200970345A EA 200970345 A EA200970345 A EA 200970345A EA 200970345 A1 EA200970345 A1 EA 200970345A1
Authority
EA
Eurasian Patent Office
Prior art keywords
stannsoporfin
hyperbilirubinemia
newborns
treatment
low dosing
Prior art date
Application number
EA200970345A
Other languages
English (en)
Inventor
Бенджамин Левинсон
Саймон Туллок
Original Assignee
Инфакэар Фармасьютикал Корпорейшн
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Инфакэар Фармасьютикал Корпорейшн filed Critical Инфакэар Фармасьютикал Корпорейшн
Publication of EA200970345A1 publication Critical patent/EA200970345A1/ru

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7135—Compounds containing heavy metals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/02—Stomatological preparations, e.g. drugs for caries, aphtae, periodontitis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/16—Otologicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Abstract

Описаны способы лечения гипербилирубинемии новорожденных с использованием станнсопорфина. Способы по изобретению позволяют лечить различные популяции пациентов более низкими дозами станнсопорфина чем те, которые ранее считались эффективными, что дает преимущества при терапевтическом введении.
EA200970345A 2006-10-04 2007-10-04 Лечение гипербилирубинемии новорожденных с использованием низких дозировок станнсопорфина EA200970345A1 (ru)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US84950906P 2006-10-04 2006-10-04
PCT/US2007/021486 WO2008045378A2 (en) 2006-10-04 2007-10-04 Treatment of infant hyperbilirubinemia using low dosages of stannsoporfin

Publications (1)

Publication Number Publication Date
EA200970345A1 true EA200970345A1 (ru) 2009-10-30

Family

ID=39036883

Family Applications (1)

Application Number Title Priority Date Filing Date
EA200970345A EA200970345A1 (ru) 2006-10-04 2007-10-04 Лечение гипербилирубинемии новорожденных с использованием низких дозировок станнсопорфина

Country Status (13)

Country Link
US (1) US20080113955A1 (ru)
EP (1) EP2076273A2 (ru)
JP (1) JP2010505854A (ru)
KR (1) KR20090079916A (ru)
CN (1) CN101631554A (ru)
AU (1) AU2007307112A1 (ru)
BR (1) BRPI0717774A2 (ru)
CA (1) CA2664934A1 (ru)
EA (1) EA200970345A1 (ru)
IL (1) IL197839A0 (ru)
MX (1) MX2009003532A (ru)
NO (1) NO20091580L (ru)
WO (1) WO2008045378A2 (ru)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7375216B2 (en) 2002-06-04 2008-05-20 Infacare Pharmaceutical Corporation Preparation of metal mesoporphyrin compounds
US20060222668A1 (en) * 2005-04-01 2006-10-05 Wellspring Pharmaceutical Corporation Stannsoporfin compositions, drug products and methods of manufacture
NZ576030A (en) 2006-10-04 2012-06-29 Infacare Pharmaceutical Corp High-purity large-scale preparation of stannsoporfin
US20090293326A1 (en) * 2008-05-29 2009-12-03 Bedford Nieves-Cruz Hyperbilirubinemia management calendar
PT2691398T (pt) 2011-03-30 2017-01-02 Infacare Pharmaceutical Corp Métodos para sintetizar mesoporfirinas de metal
WO2013082559A1 (en) * 2011-12-01 2013-06-06 Infacare Pharmaceutical Corporation Methods for treating hyperbilirubinemia with stannsoporfin
AU2017263628A1 (en) * 2016-05-12 2018-12-06 Infacare Pharmaceutical Corporation Methods for treating hyperbilirubinemia with stannsoporfin and phototherapy
WO2021126855A1 (en) * 2019-12-16 2021-06-24 Mallinckrodt Hospital Products IP Unlimited Company Methods for treating progressive hyperbilirubinemia

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US5990363A (en) * 1987-01-02 1999-11-23 Sun Company, Inc. Method for oxidizing alkanes using novel porphyrins synthesized from dipyrromethanes and aldehydes
US4900871A (en) * 1987-01-02 1990-02-13 Sun Refining And Marketing Company Hydrocarbon oxidations catalyzed by iron coordination complexes containing a halogenated ligand
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US5192757A (en) * 1990-12-20 1993-03-09 Glaxo Inc. Cobalt porphyrins
US5817830A (en) * 1992-08-14 1998-10-06 Trustees Of The University Of Pennsylvania Pyrrolic compounds
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US5371199B1 (en) * 1992-08-14 1995-12-26 Univ Pennsylvania Substituted porphyrins porphyrin-containing polymers and synthetic methods therefor
AU7103594A (en) * 1993-06-14 1995-01-03 Rockefeller University, The Treatment of neonatal hyperbilirubin with metalloporphyrin
CA2130853A1 (en) * 1994-08-25 1996-02-26 Svetlana Kudrevich Process for the syntheses of monosulphonated phthalocyanines, naphthobenzoporphyrazines and porphyrins via a modified meerwein reaction
US5912341A (en) * 1995-03-14 1999-06-15 Hoffman/Barrett, L.L.C. Heteroatom-functionalized porphyrazines and multimetallic complexes and polymers derived therefrom
US5929064A (en) * 1995-08-02 1999-07-27 Warner-Lambert Company Amino acid complexes of cobalt (III) mesoporphyrin IX and cobalt (III) protoporphyrin IX
US5883246A (en) * 1996-03-07 1999-03-16 Qlt Phototherapeutics, Inc. Synthesis of polypyrrolic macrocycles from meso-substituted tripyrrane compounds
US6004530A (en) * 1996-06-04 1999-12-21 Roche Diagnostics Gmbh Use of metallo-porphyrin conjugates for the detection of biological substances
GB9616353D0 (en) * 1996-08-03 1996-09-11 Secr Defence Metallo-porphyrins
US6124452A (en) * 1997-12-19 2000-09-26 University Of Nebraska-Lincoln Octafluoro-meso-tetraarylporphyrins and methods for making these compounds
DE19706490C1 (de) * 1997-02-19 1998-09-17 Deutsches Krebsforsch Verfahren zur Herstellung von Säureamiden und zur Metallierung von Verbindungen und Verwendung der nach den Verfahren hergestellten Verbindungen
US5886173A (en) * 1997-07-30 1999-03-23 Pharmacyclics, Inc. Metallation of macrocycles with 2,4-dicarbonyl-metal complexes
US6194566B1 (en) * 1997-12-02 2001-02-27 Schering Aktiengesellschaft Process for the production of metalloporphyrin-metal complex conjugates
JP3673888B2 (ja) * 1998-03-09 2005-07-20 独立行政法人科学技術振興機構 ポルフィリン類金属錯体の製造方法
DE19831217A1 (de) * 1998-07-03 2000-01-05 Schering Ag Neue Porphyrinderivate, diese enthaltende pharmazeutische Mittel und ihre Verwendung in der photodynamischen Therapie und MRI-Diagnostik
US5973141A (en) * 1998-11-27 1999-10-26 Miravant Pharmaceuticals, Inc. Method for the demethoxycarbonylation of porphyrinic compounds such as pheophorbides
US6462192B2 (en) * 2001-01-23 2002-10-08 Miravant Pharmaceuticals, Inc. Processes for large scale production of tetrapyrroles
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JP4309839B2 (ja) * 2002-06-04 2009-08-05 インファケア・ファーマシューティカル・コーポレイション 金属メソポルフィリンハライド化合物の調製
US7375216B2 (en) * 2002-06-04 2008-05-20 Infacare Pharmaceutical Corporation Preparation of metal mesoporphyrin compounds
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US20060222668A1 (en) * 2005-04-01 2006-10-05 Wellspring Pharmaceutical Corporation Stannsoporfin compositions, drug products and methods of manufacture

Also Published As

Publication number Publication date
JP2010505854A (ja) 2010-02-25
AU2007307112A1 (en) 2008-04-17
IL197839A0 (en) 2009-12-24
CN101631554A (zh) 2010-01-20
EP2076273A2 (en) 2009-07-08
CA2664934A1 (en) 2008-04-17
MX2009003532A (es) 2009-06-26
US20080113955A1 (en) 2008-05-15
WO2008045378A3 (en) 2008-06-05
NO20091580L (no) 2009-05-04
KR20090079916A (ko) 2009-07-22
WO2008045378A2 (en) 2008-04-17
BRPI0717774A2 (pt) 2014-04-29

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