EA200900126A1 - Способ проведения реакций типа гриньяра в микрореакторах - Google Patents

Способ проведения реакций типа гриньяра в микрореакторах

Info

Publication number
EA200900126A1
EA200900126A1 EA200900126A EA200900126A EA200900126A1 EA 200900126 A1 EA200900126 A1 EA 200900126A1 EA 200900126 A EA200900126 A EA 200900126A EA 200900126 A EA200900126 A EA 200900126A EA 200900126 A1 EA200900126 A1 EA 200900126A1
Authority
EA
Eurasian Patent Office
Prior art keywords
reactions
griniar
microreactors
carrying
type
Prior art date
Application number
EA200900126A
Other languages
English (en)
Inventor
Доминик Роберж
Николаус Билер
Лорен Дюкри
Original Assignee
Лонца Аг
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Лонца Аг filed Critical Лонца Аг
Publication of EA200900126A1 publication Critical patent/EA200900126A1/ru

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F3/00—Compounds containing elements of Groups 2 or 12 of the Periodic Table
    • C07F3/02—Magnesium compounds
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F25/00—Flow mixers; Mixers for falling materials, e.g. solid particles
    • B01F25/40—Static mixers
    • B01F25/42—Static mixers in which the mixing is affected by moving the components jointly in changing directions, e.g. in tubes provided with baffles or obstructions
    • B01F25/421—Static mixers in which the mixing is affected by moving the components jointly in changing directions, e.g. in tubes provided with baffles or obstructions by moving the components in a convoluted or labyrinthine path
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F25/00—Flow mixers; Mixers for falling materials, e.g. solid particles
    • B01F25/40—Static mixers
    • B01F25/42—Static mixers in which the mixing is affected by moving the components jointly in changing directions, e.g. in tubes provided with baffles or obstructions
    • B01F25/421—Static mixers in which the mixing is affected by moving the components jointly in changing directions, e.g. in tubes provided with baffles or obstructions by moving the components in a convoluted or labyrinthine path
    • B01F25/423—Static mixers in which the mixing is affected by moving the components jointly in changing directions, e.g. in tubes provided with baffles or obstructions by moving the components in a convoluted or labyrinthine path by means of elements placed in the receptacle for moving or guiding the components
    • B01F25/4231—Static mixers in which the mixing is affected by moving the components jointly in changing directions, e.g. in tubes provided with baffles or obstructions by moving the components in a convoluted or labyrinthine path by means of elements placed in the receptacle for moving or guiding the components using baffles
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F33/00—Other mixers; Mixing plants; Combinations of mixers
    • B01F33/30—Micromixers
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J19/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J19/0093—Microreactors, e.g. miniaturised or microfabricated reactors
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B49/00—Grignard reactions
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00781—Aspects relating to microreactors
    • B01J2219/00851—Additional features
    • B01J2219/00867—Microreactors placed in series, on the same or on different supports
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00781—Aspects relating to microreactors
    • B01J2219/00873—Heat exchange
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00781—Aspects relating to microreactors
    • B01J2219/00889—Mixing
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00781—Aspects relating to microreactors
    • B01J2219/0095—Control aspects
    • B01J2219/00984—Residence time

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Dispersion Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Physical Or Chemical Processes And Apparatus (AREA)

Abstract

Настоящее изобретение представляет собой способ проведения реакций типа Гриньяра, включающий смешивание по крайней мере двух текучих сред в микрореакторе, в котором имеется по крайней мере два пункта ввода.
EA200900126A 2006-07-18 2007-07-11 Способ проведения реакций типа гриньяра в микрореакторах EA200900126A1 (ru)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP06014883A EP1889849A1 (en) 2006-07-18 2006-07-18 Grignard reactions in microreactors
US83192206P 2006-07-20 2006-07-20
PCT/EP2007/006127 WO2008009378A2 (en) 2006-07-18 2007-07-11 Grignard reactions in microreactors

Publications (1)

Publication Number Publication Date
EA200900126A1 true EA200900126A1 (ru) 2009-10-30

Family

ID=37450872

Family Applications (1)

Application Number Title Priority Date Filing Date
EA200900126A EA200900126A1 (ru) 2006-07-18 2007-07-11 Способ проведения реакций типа гриньяра в микрореакторах

Country Status (18)

Country Link
US (1) US7939698B2 (ru)
EP (3) EP1889849A1 (ru)
JP (1) JP5512266B2 (ru)
CN (2) CN102584514B (ru)
AT (1) ATE508132T1 (ru)
BR (1) BRPI0714394A2 (ru)
CA (1) CA2655658A1 (ru)
DE (1) DE602007014375D1 (ru)
EA (1) EA200900126A1 (ru)
ES (2) ES2399780T3 (ru)
HK (2) HK1131786A1 (ru)
IL (1) IL196112A (ru)
MX (1) MX2009000618A (ru)
MY (1) MY147861A (ru)
PL (2) PL2138500T3 (ru)
PT (1) PT2138500E (ru)
SI (2) SI2044087T1 (ru)
WO (1) WO2008009378A2 (ru)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2005533560A (ja) 2002-07-19 2005-11-10 バクスター インターナショナル インコーポレイテッド 腹膜透析を実施するためのシステムおよび方法
US7659414B2 (en) * 2007-07-20 2010-02-09 Rohm And Haas Company Method of preparing organometallic compounds
KR101536041B1 (ko) * 2010-02-09 2015-07-10 잘티고 게엠베하 전이 금속 촉매작용을 이용한 아릴, 헤테로아릴, 알킬 및 알켄 할로게나이드의 알릴화 및 비닐화 방법
CN103896737A (zh) * 2014-03-31 2014-07-02 南京工业大学 一种利用微结构反应器制备炔丙醇的方法
CN110483243A (zh) * 2019-09-17 2019-11-22 西安近代化学研究所 一种1-（2-氯苯基）-2-（1-氯环丙基）-3-氯-2-丙醇的制备方法
CN114940687A (zh) * 2022-05-30 2022-08-26 杭州瀛拓科技有限公司 一种多取代乙烯基硅（氧）烷的连续流合成方法

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH08245641A (ja) * 1995-03-13 1996-09-24 Nitto Kasei Co Ltd グリニャール試薬
GB9723260D0 (en) * 1997-11-05 1998-01-07 British Nuclear Fuels Plc A method of performing a chemical reaction
DE10001317A1 (de) * 2000-01-14 2001-07-19 Merck Patent Gmbh Reaktion von Carbonylverbindungen mit metallorganischen Reagenzien
JP2004530044A (ja) * 2001-04-12 2004-09-30 アストラゼネカ アクチボラグ 微細工学的反応装置
DE10140857A1 (de) * 2001-08-21 2003-03-06 Clariant Gmbh Verfahren zur Herstellung von Aryl- und Alkyl-Bor-Verbindungen in Mikroreaktoren
GB0203653D0 (en) * 2002-02-15 2002-04-03 Syrris Ltd A microreactor
GB0206117D0 (en) * 2002-03-15 2002-04-24 Imaging Res Solutions Ltd Use of microfabricated devices
EP1838431A4 (en) * 2004-12-03 2012-08-22 California Inst Of Techn MICROFLUIDIC DEVICES WITH CIRCUITRY OF CHEMICAL REACTIONS
EP1676632A1 (de) * 2004-12-28 2006-07-05 Covion Organic Semiconductors GmbH Verfahren zur Herstellung von Polymeren

Also Published As

Publication number Publication date
CA2655658A1 (en) 2008-01-24
BRPI0714394A2 (pt) 2013-03-12
ES2399780T3 (es) 2013-04-03
CN102584514A (zh) 2012-07-18
US7939698B2 (en) 2011-05-10
PL2138500T3 (pl) 2013-04-30
MY147861A (en) 2013-01-31
HK1173718A1 (en) 2013-05-24
WO2008009378A3 (en) 2008-03-20
CN101495488A (zh) 2009-07-29
SI2138500T1 (sl) 2013-02-28
CN102584514B (zh) 2015-05-06
EP1889849A1 (en) 2008-02-20
EP2138500B1 (en) 2012-11-21
DE602007014375D1 (de) 2011-06-16
ATE508132T1 (de) 2011-05-15
IL196112A (en) 2013-06-27
IL196112A0 (en) 2009-09-01
SI2044087T1 (sl) 2011-08-31
PL2044087T3 (pl) 2011-10-31
US20090270663A1 (en) 2009-10-29
EP2044087B1 (en) 2011-05-04
ES2365874T3 (es) 2011-10-11
MX2009000618A (es) 2009-01-29
CN101495488B (zh) 2012-08-22
EP2044087A2 (en) 2009-04-08
EP2138500A1 (en) 2009-12-30
WO2008009378A2 (en) 2008-01-24
HK1131786A1 (en) 2010-02-05
PT2138500E (pt) 2013-01-07
JP2010508239A (ja) 2010-03-18
JP5512266B2 (ja) 2014-06-04

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