EA200801575A1 - Трансдермальная доставка мептазинола - Google Patents
Трансдермальная доставка мептазинолаInfo
- Publication number
- EA200801575A1 EA200801575A1 EA200801575A EA200801575A EA200801575A1 EA 200801575 A1 EA200801575 A1 EA 200801575A1 EA 200801575 A EA200801575 A EA 200801575A EA 200801575 A EA200801575 A EA 200801575A EA 200801575 A1 EA200801575 A1 EA 200801575A1
- Authority
- EA
- Eurasian Patent Office
- Prior art keywords
- meptazinol
- meptasinola
- transdermal supply
- increases
- effective amount
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0002—Galenical forms characterised by the drug release technique; Application systems commanded by energy
- A61K9/0009—Galenical forms characterised by the drug release technique; Application systems commanded by energy involving or responsive to electricity, magnetism or acoustic waves; Galenical aspects of sonophoresis, iontophoresis, electroporation or electroosmosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
- A61K31/7052—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
- A61K47/38—Cellulose; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/44—Oils, fats or waxes according to two or more groups of A61K47/02-A61K47/42; Natural or modified natural oils, fats or waxes, e.g. castor oil, polyethoxylated castor oil, montan wax, lignite, shellac, rosin, beeswax or lanolin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/06—Ointments; Bases therefor; Other semi-solid forms, e.g. creams, sticks, gels
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
- A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
- A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
- A61K9/7084—Transdermal patches having a drug layer or reservoir, and one or more separate drug-free skin-adhesive layers, e.g. between drug reservoir and skin, or surrounding the drug reservoir; Liquid-filled reservoir patches
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Dermatology (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Inorganic Chemistry (AREA)
- Molecular Biology (AREA)
- Neurosurgery (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Pain & Pain Management (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
Abstract
Описана система доставки соли мептазинола или предшественника мептазинола, которая увеличивает биологическую доступность эффективного количества мептазинола для того, чтобы обеспечить болеутоляющий эффект. Один вариант осуществления системы доставки представляет собой трансдермальное устройство, которое увеличивает кожный поток эффективного количества мептазинола для того, чтобы обеспечить болеутоляющий эффект. Кроме того, описаны способы обеспечения болеутоляющего эффекта.
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US75335705P | 2005-12-21 | 2005-12-21 | |
US86211406P | 2006-10-19 | 2006-10-19 | |
PCT/US2006/048783 WO2007075883A2 (en) | 2005-12-21 | 2006-12-21 | Transdermal delivery of meptazinol |
Publications (1)
Publication Number | Publication Date |
---|---|
EA200801575A1 true EA200801575A1 (ru) | 2008-12-30 |
Family
ID=38198475
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
EA200801575A EA200801575A1 (ru) | 2005-12-21 | 2006-12-21 | Трансдермальная доставка мептазинола |
Country Status (15)
Country | Link |
---|---|
US (1) | US20070224253A1 (ru) |
EP (1) | EP1962817B1 (ru) |
AR (1) | AR058598A1 (ru) |
AT (1) | ATE488229T1 (ru) |
AU (1) | AU2006331596A1 (ru) |
CA (1) | CA2633369A1 (ru) |
DE (1) | DE602006018355D1 (ru) |
DK (1) | DK1962817T3 (ru) |
EA (1) | EA200801575A1 (ru) |
MX (1) | MX2008008050A (ru) |
PE (1) | PE20071163A1 (ru) |
PT (1) | PT1962817E (ru) |
TW (1) | TW200800223A (ru) |
UY (1) | UY30056A1 (ru) |
WO (1) | WO2007075883A2 (ru) |
Families Citing this family (34)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20090280064A1 (en) * | 2005-06-24 | 2009-11-12 | Rao Papineni | Transdermal delivery of optical, spect, multimodal, drug or biological cargo laden nanoparticle(s) in small animals or humans |
CA2657435A1 (en) | 2006-07-10 | 2008-07-03 | Medipacs, Inc. | Super elastic epoxy hydrogel |
WO2009073734A2 (en) | 2007-12-03 | 2009-06-11 | Medipacs, Inc. | Fluid metering device |
WO2009092073A2 (en) * | 2008-01-18 | 2009-07-23 | Shire Llc | Amino acid and peptide prodrugs of opioid analgesics with reduced gi side-effects |
CN105902482A (zh) * | 2008-06-25 | 2016-08-31 | Fe3医学有限公司 | 用于经皮递送治疗有效量的铁的贴片和方法 |
US8190252B2 (en) | 2009-02-12 | 2012-05-29 | Incube Labs, Llc | Iontophoretic system for transdermal delivery of active agents for therapeutic and medicinal purposes |
US8961492B2 (en) | 2009-02-12 | 2015-02-24 | Incube Labs, Llc | System and method for controlling the iontophoretic delivery of therapeutic agents based on user inhalation |
US9095503B2 (en) | 2009-02-12 | 2015-08-04 | Incube Labs, Llc | System and method for biphasic transdermal iontophreotic delivery of therapeutic agents |
WO2010093472A2 (en) * | 2009-02-12 | 2010-08-19 | Incube Labs, Llc | Method and apparatus for oscillatory iontophoretic transdermal delivery of a therapeutic agent |
US8821945B2 (en) | 2009-04-25 | 2014-09-02 | Fe3 Medical, Inc. | Method for transdermal iontophoretic delivery of chelated agents |
US8423131B2 (en) * | 2009-06-26 | 2013-04-16 | Incube Labs, Llc | Corrosion resistant electrodes for iontophoretic transdermal delivery devices and methods of use |
WO2011032011A1 (en) | 2009-09-10 | 2011-03-17 | Medipacs, Inc. | Low profile actuator and improved method of caregiver controlled administration of therapeutics |
WO2011044175A2 (en) | 2009-10-06 | 2011-04-14 | Incube Labs, Llc | Patch and patch assembly for iontophoretic transdermal delivery of active agents for therapeutic and medicinal purposes |
US8685038B2 (en) | 2009-12-07 | 2014-04-01 | Incube Labs, Llc | Iontophoretic apparatus and method for marking of the skin |
US9500186B2 (en) | 2010-02-01 | 2016-11-22 | Medipacs, Inc. | High surface area polymer actuator with gas mitigating components |
AU2011213557B2 (en) | 2010-02-05 | 2015-05-07 | Phosphagenics Limited | Carrier comprising non-neutralised tocopheryl phosphate |
WO2011100376A2 (en) | 2010-02-10 | 2011-08-18 | Incube Labs, Llc | Methods and architecture for power optimization of iontophoretic transdermal drug delivery |
RU2553350C2 (ru) | 2010-03-30 | 2015-06-10 | Фосфейдженикс Лимитед | Трансдермальные пластыри |
WO2012061556A1 (en) | 2010-11-03 | 2012-05-10 | Flugen, Inc. | Wearable drug delivery device having spring drive and sliding actuation mechanism |
WO2012122586A1 (en) | 2011-03-15 | 2012-09-20 | Phosphagenics Limited | New composition |
WO2012154704A2 (en) | 2011-05-06 | 2012-11-15 | Incube Labs, Llc | System and method for biphasic transdermal iontophoretic delivery of therapeutic agents for the control of addictive cravings |
US8636696B2 (en) | 2011-06-10 | 2014-01-28 | Kimberly-Clark Worldwide, Inc. | Transdermal device containing microneedles |
EP2847249A4 (en) | 2012-03-14 | 2016-12-28 | Medipacs Inc | SMART POLYMER MATERIALS WITH EXCESSIVE REACTIVE MOLECULES |
WO2014132239A1 (en) | 2013-02-28 | 2014-09-04 | Kimberly-Clark Worldwide, Inc. | Drug delivery device |
CN109621083B (zh) | 2013-02-28 | 2022-03-22 | 索伦托治疗有限公司 | 药物递送装置 |
US10376308B2 (en) | 2015-02-05 | 2019-08-13 | Axon Therapies, Inc. | Devices and methods for treatment of heart failure by splanchnic nerve ablation |
EP3383371B1 (en) | 2015-12-09 | 2024-05-01 | Avecho Biotechnology Limited | Pharmaceutical formulation |
CA3031766A1 (en) | 2016-07-29 | 2018-02-01 | Howard Levin | Devices, systems, and methods for treatment of heart failure by splanchnic nerve ablation |
JP7198754B2 (ja) | 2016-12-21 | 2023-01-04 | アベーチョ バイオテクノロジー リミテッド | 方法 |
WO2019118976A1 (en) | 2017-12-17 | 2019-06-20 | Axon Therapies, Inc. | Methods and devices for endovascular ablation of a splanchnic nerve |
JP7334167B2 (ja) | 2018-01-26 | 2023-08-28 | アクソン セラピーズ,インク. | 内臓神経の血管内アブレーションの為の方法及びデバイス |
CN113825464A (zh) | 2019-06-20 | 2021-12-21 | 阿克松疗法公司 | 用于内脏神经的血管内消融的方法和装置 |
US11413090B2 (en) | 2020-01-17 | 2022-08-16 | Axon Therapies, Inc. | Methods and devices for endovascular ablation of a splanchnic nerve |
CN113491675B (zh) * | 2021-07-01 | 2023-05-23 | 北京航空航天大学 | 一种预防瘢痕的微针创口贴及其制备方法 |
Family Cites Families (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB1539277A (en) * | 1977-09-16 | 1979-01-31 | Wyeth John & Brother Ltd | Hexahydro-1h-azepines |
IE55189B1 (en) * | 1982-07-08 | 1990-06-20 | Wyeth John & Brother Ltd | Pharmaceutical compositions |
IE60941B1 (en) * | 1986-07-10 | 1994-09-07 | Elan Transdermal Ltd | Transdermal drug delivery device |
US6916486B2 (en) * | 1996-02-19 | 2005-07-12 | Acrux Dds Pty Ltd | Transdermal delivery of analgesics |
DE69939019D1 (de) * | 1998-07-07 | 2008-08-14 | Transdermal Technologies Inc | Zusammensetzungen für die schnelle und nicht-irritierende transdermale verabreichung von pharmazeutika and verfahren zur formuliering davon und ihren verabreichung |
US6716449B2 (en) * | 2000-02-08 | 2004-04-06 | Euro-Celtique S.A. | Controlled-release compositions containing opioid agonist and antagonist |
DE10059415A1 (de) * | 2000-11-30 | 2002-06-06 | Gruenenthal Gmbh | Verwendung von schwachen Opioiden und gemischten Opioidagonisten/-antagonisten zur Therapie der Harninkontinenz |
DE60326354D1 (de) * | 2002-08-20 | 2009-04-09 | Euro Celtique Sa | Transdermale dosierungsform enthaltend einen wirkstoff und einen antagonisten in freier base und in salz form |
MY141815A (en) * | 2003-04-30 | 2010-06-30 | Purdue Pharma Lp | Tamper-resistant transdermal dosage form comprising an active agent component and an adverse agent component at the distal site of the active agent layer |
-
2006
- 2006-12-20 TW TW095147948A patent/TW200800223A/zh unknown
- 2006-12-21 UY UY30056A patent/UY30056A1/es not_active Application Discontinuation
- 2006-12-21 EP EP06848981A patent/EP1962817B1/en not_active Not-in-force
- 2006-12-21 EA EA200801575A patent/EA200801575A1/ru unknown
- 2006-12-21 DK DK06848981.4T patent/DK1962817T3/da active
- 2006-12-21 DE DE602006018355T patent/DE602006018355D1/de active Active
- 2006-12-21 US US11/614,165 patent/US20070224253A1/en not_active Abandoned
- 2006-12-21 AT AT06848981T patent/ATE488229T1/de active
- 2006-12-21 WO PCT/US2006/048783 patent/WO2007075883A2/en active Application Filing
- 2006-12-21 AR ARP060105700A patent/AR058598A1/es unknown
- 2006-12-21 MX MX2008008050A patent/MX2008008050A/es unknown
- 2006-12-21 PE PE2006001676A patent/PE20071163A1/es not_active Application Discontinuation
- 2006-12-21 CA CA002633369A patent/CA2633369A1/en not_active Abandoned
- 2006-12-21 AU AU2006331596A patent/AU2006331596A1/en not_active Abandoned
- 2006-12-21 PT PT06848981T patent/PT1962817E/pt unknown
Also Published As
Publication number | Publication date |
---|---|
AR058598A1 (es) | 2008-02-13 |
PT1962817E (pt) | 2010-12-13 |
US20070224253A1 (en) | 2007-09-27 |
DE602006018355D1 (de) | 2010-12-30 |
AU2006331596A1 (en) | 2007-07-05 |
EP1962817B1 (en) | 2010-11-17 |
WO2007075883A9 (en) | 2007-08-23 |
ATE488229T1 (de) | 2010-12-15 |
WO2007075883A2 (en) | 2007-07-05 |
TW200800223A (en) | 2008-01-01 |
WO2007075883A3 (en) | 2008-01-17 |
EP1962817A2 (en) | 2008-09-03 |
CA2633369A1 (en) | 2007-07-05 |
MX2008008050A (es) | 2009-04-06 |
PE20071163A1 (es) | 2007-11-30 |
DK1962817T3 (da) | 2011-03-07 |
UY30056A1 (es) | 2007-06-29 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
EA200801575A1 (ru) | Трансдермальная доставка мептазинола | |
DK2117521T3 (da) | Transdermale indgivelsessystemer omfattende bupivacain | |
DK2219603T3 (da) | Transdermalt afgivelsessystem | |
DK2274032T3 (da) | Anordning til medicinindgivelse | |
EA201001402A1 (ru) | Фармацевтические растворы, способ получения и терапевтическое применение | |
EA200802146A1 (ru) | Трансдермальные способы и системы доставки препаратов против мигрени | |
BRPI0913214A2 (pt) | sistema de fornecimento de drogas transdérmico estabilizado | |
DE602007007991D1 (de) | Kleinvolumige, orale, transmukosale dosierungsformen mit sufentanil zur schmerzbehandlung | |
DK2185220T3 (da) | Anordning til lægemiddelfremføring | |
HK1132921A1 (en) | Transdermal therapeutic system for administering the active substance buprenorphine | |
DE602009000290D1 (de) | Transdermales Arzneimittelabgabesystem für flüssige Aktivsubstanzen | |
ECSP088904A (es) | Arilimidazolonas y ariltriazolonas sustituidas como inhibidores de receptores de vasopresina | |
ZA200902579B (en) | Transdermal therapeutic system with high rate of utilization of active substance and dosing accuracy | |
BRPI0909653A2 (pt) | sistema terapêutico transdérmico com membrama estabilizada | |
ME01459B (me) | Postupak za doziranje medikamenata | |
IN2012DN01225A (ru) | ||
AT500095B8 (de) | Transdermales abgabesystem | |
EA201400628A1 (ru) | Трансдермальная терапевтическая система для введения фентанила или его аналога | |
CL2015002847A1 (es) | Sistemas y métodos para tratar una respuesta farmacodinámica adversa inducida por opioides (divisional de la solicitud n° 0110-2015). | |
EA201400737A1 (ru) | Система доставки на основе множества пеллет с немедленным высвобождением активного вещества | |
ATE401870T1 (de) | Transdermales therapeutisches system zur verabreichung von analgetika | |
AT509344A5 (de) | Vorrichtung zum gesteuerten auslösen von lawinen | |
MX2016007370A (es) | Agente terapeutico y/o preventivo que comprende un derivado de 1-indansulfamida para el dolor. | |
CR20110022A (es) | Nuevas posibilidades de lucha contra la giardiasis | |
EA200970816A1 (ru) | Новая лекарственная форма |