EA200800299A1 - Водные анестезирующие композиции, содержащие пропофол - Google Patents

Водные анестезирующие композиции, содержащие пропофол

Info

Publication number
EA200800299A1
EA200800299A1 EA200800299A EA200800299A EA200800299A1 EA 200800299 A1 EA200800299 A1 EA 200800299A1 EA 200800299 A EA200800299 A EA 200800299A EA 200800299 A EA200800299 A EA 200800299A EA 200800299 A1 EA200800299 A1 EA 200800299A1
Authority
EA
Eurasian Patent Office
Prior art keywords
prophofol
anesthesic
water
compositions containing
propofol
Prior art date
Application number
EA200800299A
Other languages
English (en)
Other versions
EA014673B1 (ru
Inventor
Гаутам Винод Дафтари
Срикант Аннаппа Пай
Мангеш Маникрао Кулькарни
Original Assignee
Бхарат Сирумс Энд Вэксинс Лтд.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Бхарат Сирумс Энд Вэксинс Лтд. filed Critical Бхарат Сирумс Энд Вэксинс Лтд.
Publication of EA200800299A1 publication Critical patent/EA200800299A1/ru
Publication of EA014673B1 publication Critical patent/EA014673B1/ru

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/045—Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
    • A61K31/05—Phenols
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/16—Amides, e.g. hydroxamic acids
    • A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
    • A61K31/167—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide having the nitrogen of a carboxamide group directly attached to the aromatic ring, e.g. lidocaine, paracetamol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/69—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit
    • A61K47/6949—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit inclusion complexes, e.g. clathrates, cavitates or fullerenes
    • A61K47/6951—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit inclusion complexes, e.g. clathrates, cavitates or fullerenes using cyclodextrin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/08—Solutions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P23/00—Anaesthetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P23/00—Anaesthetics
    • A61P23/02—Local anaesthetics
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B82—NANOTECHNOLOGY
    • B82Y—SPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
    • B82Y5/00—Nanobiotechnology or nanomedicine, e.g. protein engineering or drug delivery

Abstract

В изобретении предложена водная анестезирющая композиция пропофола, которая является стабильной, стерилизуемой в автоклаве, пригодной для парентерального введения и имеет уменьшенную частоту возникновения боли при инъекции. Композиция включает в себя пропофол, 2-гидроксипропил-β-циклодекстрин и местное анестезирующее средство лидокаин.
EA200800299A 2005-08-12 2006-08-11 Водные анестезирующие композиции, содержащие пропофол EA014673B1 (ru)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IN940MU2005 2005-08-12
PCT/IN2006/000299 WO2007052295A2 (en) 2005-08-12 2006-08-11 Aqueous anaesthetic compositions comprising propofol

Publications (2)

Publication Number Publication Date
EA200800299A1 true EA200800299A1 (ru) 2008-08-29
EA014673B1 EA014673B1 (ru) 2010-12-30

Family

ID=37964321

Family Applications (1)

Application Number Title Priority Date Filing Date
EA200800299A EA014673B1 (ru) 2005-08-12 2006-08-11 Водные анестезирующие композиции, содержащие пропофол

Country Status (13)

Country Link
US (1) US20090203794A1 (ru)
EP (1) EP1928412B1 (ru)
JP (1) JP2009504634A (ru)
KR (1) KR20080055804A (ru)
CN (1) CN101287447B (ru)
AU (1) AU2006310044A1 (ru)
BR (1) BRPI0614628A2 (ru)
CA (1) CA2618799C (ru)
EA (1) EA014673B1 (ru)
IL (1) IL189473A0 (ru)
MX (1) MX2008001981A (ru)
WO (1) WO2007052295A2 (ru)
ZA (1) ZA200801393B (ru)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2535001C1 (ru) * 2013-07-11 2014-12-10 Общество с ограниченной ответственностью "ВИК-здоровье животных" Микроколлоидный раствор пропофола для анестезии

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2484350B1 (de) * 2011-02-04 2016-04-20 Roewer, Norbert, Univ.-Prof. Dr. med. Pharmazeutische Zubereitung, enthaltend einen Komplex eines Propofolsalzes mit einem Cyclodextrin
JP6923447B2 (ja) * 2015-03-27 2021-08-18 グリュネンタール・ゲゼルシャフト・ミト・ベシュレンクテル・ハフツング タペンタドールの非経口投与のための安定な製剤
CN104800396A (zh) * 2015-04-29 2015-07-29 张如意 一种麻醉剂及其制备方法和使用方法
CN105496953A (zh) * 2016-01-25 2016-04-20 温州科技职业学院 一种犬用复方丙泊酚水性注射液及其制备方法与应用
CN106109468A (zh) * 2016-07-11 2016-11-16 孙剑 一种女性发育期注射麻醉剂
RU2648441C2 (ru) * 2016-09-13 2018-03-26 Казимир Иосифович Пашкевич Средство для местной анестезии (варианты)
CN116350579A (zh) * 2018-11-07 2023-06-30 比卡生物科技（广州）有限公司 一种澄清丙泊酚注射液及其制备方法
WO2021158573A1 (en) * 2020-02-03 2021-08-12 Natural Extraction Systems, LLC Methods related to bioactive agents that convert from anions to molecules

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4067997A (en) * 1975-05-21 1978-01-10 Med-Chem Laboratories Synergistic microbecidal composition and method
GB9405593D0 (en) * 1994-03-22 1994-05-11 Zeneca Ltd Pharmaceutical compositions
ZA962214B (en) * 1995-04-10 1996-10-07 Farmarc Nederland Bv Pharmaceutical composition
BR9907832A (pt) * 1998-02-10 2000-10-31 Sicor Inc Composição de propofol contendo sulfito
US6028108A (en) * 1998-10-22 2000-02-22 America Home Products Corporation Propofol composition comprising pentetate
US6140373A (en) * 1998-10-23 2000-10-31 Abbott Laboratories Propofol composition
US6140374A (en) * 1998-10-23 2000-10-31 Abbott Laboratories Propofol composition
US6100302A (en) * 1999-04-05 2000-08-08 Baxter International Inc. Propofol formulation with enhanced microbial characteristics
IN187686B (ru) * 2000-06-21 2002-06-08 Bharat Serums & Vaccines Ltd
EP1337273A2 (en) * 2000-11-28 2003-08-27 Transform Pharmaceuticals, Inc. Pharmaceutical formulations comprising paclitaxel, derivatives, and pharmaceutically acceptable salts thereof
US7034013B2 (en) * 2001-03-20 2006-04-25 Cydex, Inc. Formulations containing propofol and a sulfoalkyl ether cyclodextrin
WO2002074200A1 (en) * 2001-03-20 2002-09-26 Cydex, Inc. Formulations containing propofol and a sulfoalkyl ether cyclodextrin
BR0307518A (pt) * 2002-02-01 2004-12-28 Shimoda Biotech Pty Ltd Composição farmacêutica
WO2004108113A1 (en) * 2003-06-10 2004-12-16 Dinesh Shantilal Patel Improved novel, clear, painless preparation of propofol

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2535001C1 (ru) * 2013-07-11 2014-12-10 Общество с ограниченной ответственностью "ВИК-здоровье животных" Микроколлоидный раствор пропофола для анестезии

Also Published As

Publication number Publication date
CN101287447B (zh) 2012-10-24
JP2009504634A (ja) 2009-02-05
AU2006310044A1 (en) 2007-05-10
KR20080055804A (ko) 2008-06-19
CA2618799A1 (en) 2007-05-10
EA014673B1 (ru) 2010-12-30
BRPI0614628A2 (pt) 2011-04-12
US20090203794A1 (en) 2009-08-13
MX2008001981A (es) 2008-03-25
WO2007052295A3 (en) 2007-07-26
CN101287447A (zh) 2008-10-15
ZA200801393B (en) 2009-01-28
CA2618799C (en) 2013-06-04
EP1928412B1 (en) 2015-09-16
WO2007052295A2 (en) 2007-05-10
EP1928412A2 (en) 2008-06-11
IL189473A0 (en) 2008-08-07

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TK4A Corrections in published eurasian patents
MM4A Lapse of a eurasian patent due to non-payment of renewal fees within the time limit in the following designated state(s)

Designated state(s): AM AZ BY KZ KG MD TJ TM RU