EA200000918A1 - Способ изготовления глазных препаратов местного применения без общих действий - Google Patents
Способ изготовления глазных препаратов местного применения без общих действийInfo
- Publication number
- EA200000918A1 EA200000918A1 EA200000918A EA200000918A EA200000918A1 EA 200000918 A1 EA200000918 A1 EA 200000918A1 EA 200000918 A EA200000918 A EA 200000918A EA 200000918 A EA200000918 A EA 200000918A EA 200000918 A1 EA200000918 A1 EA 200000918A1
- Authority
- EA
- Eurasian Patent Office
- Prior art keywords
- drugs
- timolol
- clonidine
- preparations
- topically
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0048—Eye, e.g. artificial tears
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/32—Macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. carbomers, poly(meth)acrylates, or polyvinyl pyrrolidone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
Landscapes
- Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Ophthalmology & Optometry (AREA)
- General Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Epidemiology (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
Abstract
Для лечения глазных болезней используются различные лекарственные средства. Они используются в виде препаратов местного применения или в виде препаратов общего действия, принимаемых орально или парентерально. Среди препаратов местного применения некоторые используются только местно, например фрамицетин, неомицин, лотепреднола эбаноат и т.п. Однако подавляющее большинство глазных лекарств местного применения используются также и для общего действия, например ципрофлокацин, гентамицин, тимолол, клонидин, дексаметазон, бетаметазон, карбахол и т.п. Обнаружено, что некоторые из этих лекарств при местном использовании имеют также общие действия, и, если они серьёзны по своей природе, это ограничивает использование данного лекарства, например сердечно-лёгочные действия таких В-блокирующих средств, как тимолол. Сухость во рту, прилив крови, жар, тахикардия, задержка мочи, судорожная возбудимость при атропине. Гипертензия при фенилэфрине. Повышенное слюноотделение, тошнота, рвота, понос, спазм желудка, бронхиальные выделения, сужение бронхов, астма, брадикардия, парестезия при средствах, вызывающих сужение зрачка, гипотензия при клонидине. Сухость во рту, утомление и сонливость при апраклонидине и бримонидине.Отчет о международном поиске был опубликован 2001.02.13.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IN90BO1999 IN185228B (ru) | 1999-02-03 | 1999-02-03 | |
| PCT/IN2000/000008 WO2000049990A2 (en) | 1999-02-03 | 2000-02-02 | The process for manufacturing topical ophthalmic preparations without systemic effects |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| EA200000918A1 true EA200000918A1 (ru) | 2001-10-22 |
Family
ID=11077485
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| EA200000918A EA200000918A1 (ru) | 1999-02-03 | 2000-02-02 | Способ изготовления глазных препаратов местного применения без общих действий |
Country Status (11)
| Country | Link |
|---|---|
| EP (1) | EP1139970A2 (ru) |
| AP (1) | AP2000001977A0 (ru) |
| AU (1) | AU4429100A (ru) |
| BR (1) | BR0004530A (ru) |
| CA (1) | CA2326690A1 (ru) |
| EA (1) | EA200000918A1 (ru) |
| ID (1) | ID28121A (ru) |
| IL (1) | IL138824A0 (ru) |
| IN (1) | IN185228B (ru) |
| WO (1) | WO2000049990A2 (ru) |
| ZA (1) | ZA200006252B (ru) |
Families Citing this family (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US8858961B2 (en) | 2000-07-14 | 2014-10-14 | Allergan, Inc. | Compositions containing alpha-2-adrenergic agonist components |
| AU2005220199B2 (en) * | 2000-07-14 | 2007-03-08 | Allergan, Inc. | Compositions containing alpha-2-adrenergic agonist components |
| NZ521185A (en) * | 2000-07-14 | 2005-02-25 | Allergan Inc | Compositions containing alpha-2-adrenergic agonist components |
| DE10132876A1 (de) * | 2001-07-06 | 2003-01-30 | Medproject Pharma Entwicklungs | Zweiphasige, tropfbare Hydrogele zur Anwendung am Auge |
| US7439241B2 (en) | 2003-05-27 | 2008-10-21 | Galderma Laboratories, Inc. | Compounds, formulations, and methods for treating or preventing rosacea |
| ES2647618T3 (es) | 2004-05-25 | 2017-12-22 | Galderma Pharma S.A. | Compuestos, formulaciones y procedimientos para tratar o prevenir trastornos inflamatorios de la piel |
| EP2329849B1 (en) | 2009-11-18 | 2015-04-29 | Galderma Research & Development | Combination of alpha-2 adrenergic receptor agonist and non-steroidal anti-inflammatory agent for treating or preventing an inflammatory skin disorder |
| FR2977493B1 (fr) | 2011-07-05 | 2014-02-14 | Galderma Res & Dev | Nouvelle composition anesthesique stable pour la reduction des reactions cutanees |
| WO2014127243A1 (en) | 2013-02-15 | 2014-08-21 | Allergan, Inc. | Sustained drug delivery implant |
| WO2014150899A1 (en) * | 2013-03-15 | 2014-09-25 | Chapin Matthew J | Topical ophthalmic formulations for treating migraine |
| US9421199B2 (en) | 2014-06-24 | 2016-08-23 | Sydnexis, Inc. | Ophthalmic composition |
| WO2016172712A2 (en) | 2015-04-23 | 2016-10-27 | Sydnexis, Inc. | Ophthalmic composition |
| US11382909B2 (en) | 2014-09-05 | 2022-07-12 | Sydnexis, Inc. | Ophthalmic composition |
| US11052094B2 (en) | 2015-05-29 | 2021-07-06 | Sydnexis, Inc. | D2O stabilized pharmaceutical formulations |
| GB202110420D0 (en) * | 2021-07-20 | 2021-09-01 | Rosemont Pharmaceuticals Ltd | Liquid pharmaceutical composition of clonidine |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS6056684B2 (ja) * | 1977-11-07 | 1985-12-11 | 東興薬品工業株式会社 | 点眼剤 |
| DD294174A5 (de) * | 1990-05-04 | 1991-09-26 | Sigrid Keipert | Ophthalmika mit retardwirkung und ein neues verfahren zu ihrer herstellung |
| FR2678832B1 (fr) * | 1991-07-10 | 1995-03-17 | Europhta Sa Laboratoire | Nouvelles compositions ophtalmiques a resorption amelioree et leurs procedes de preparation. |
| FR2679773A1 (fr) * | 1991-07-30 | 1993-02-05 | Merck Sharp & Dohme | Preparation ophtalmique contenant un agent osmotique acceptable antimicrobien. |
| DE19614823A1 (de) * | 1996-04-15 | 1997-10-16 | Mann Gerhard Chem Pharm Fab | Ophthalmische Zusammensetzung mit verlängerter Verweilzeit am Auge |
-
1999
- 1999-02-03 IN IN90BO1999 patent/IN185228B/en unknown
-
2000
- 2000-02-02 AP APAP/P/2000/001977A patent/AP2000001977A0/en unknown
- 2000-02-02 ID IDW20002252A patent/ID28121A/id unknown
- 2000-02-02 EP EP00925571A patent/EP1139970A2/en not_active Withdrawn
- 2000-02-02 AU AU44291/00A patent/AU4429100A/en not_active Abandoned
- 2000-02-02 IL IL13882400A patent/IL138824A0/xx unknown
- 2000-02-02 CA CA002326690A patent/CA2326690A1/en not_active Abandoned
- 2000-02-02 EA EA200000918A patent/EA200000918A1/ru unknown
- 2000-02-02 WO PCT/IN2000/000008 patent/WO2000049990A2/en not_active Application Discontinuation
- 2000-02-02 BR BR0004530-6A patent/BR0004530A/pt active Pending
- 2000-11-01 ZA ZA200006252A patent/ZA200006252B/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| IN185228B (ru) | 2000-12-09 |
| WO2000049990A3 (en) | 2001-07-26 |
| AU4429100A (en) | 2000-09-14 |
| ZA200006252B (en) | 2001-11-29 |
| IL138824A0 (en) | 2001-10-31 |
| ID28121A (id) | 2001-05-03 |
| EP1139970A2 (en) | 2001-10-10 |
| WO2000049990A2 (en) | 2000-08-31 |
| AP2000001977A0 (en) | 2000-12-31 |
| BR0004530A (pt) | 2001-04-03 |
| CA2326690A1 (en) | 2000-08-31 |
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