EA200000623A1 - Гиполипидемические бензотиазепиновые соединения - Google Patents

Гиполипидемические бензотиазепиновые соединения

Info

Publication number
EA200000623A1
EA200000623A1 EA200000623A EA200000623A EA200000623A1 EA 200000623 A1 EA200000623 A1 EA 200000623A1 EA 200000623 A EA200000623 A EA 200000623A EA 200000623 A EA200000623 A EA 200000623A EA 200000623 A1 EA200000623 A1 EA 200000623A1
Authority
EA
Eurasian Patent Office
Prior art keywords
compounds
benzothiazepine compounds
application
hypolipidemic benzothiazepine
hypolipidemic
Prior art date
Application number
EA200000623A
Other languages
English (en)
Inventor
Энтони Луис Хандлон
Original Assignee
Глаксо Груп Лимитед
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Глаксо Груп Лимитед filed Critical Глаксо Груп Лимитед
Publication of EA200000623A1 publication Critical patent/EA200000623A1/ru

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D281/00—Heterocyclic compounds containing rings of more than six members having one nitrogen atom and one sulfur atom as the only ring hetero atoms
    • C07D281/02—Seven-membered rings
    • C07D281/04—Seven-membered rings having the hetero atoms in positions 1 and 4
    • C07D281/08—Seven-membered rings having the hetero atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems
    • C07D281/10—Seven-membered rings having the hetero atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems condensed with one six-membered ring
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Vascular Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen- Or Sulfur-Containing Heterocyclic Ring Compounds With Rings Of Six Or More Members (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Thiazole And Isothizaole Compounds (AREA)

Abstract

Настоящее изобретение относится к новым гиполипидемическим соединениям формулы (I), где Rпредставляет собой H или метил, и их солям, сольватам или физиологически функциональным производным, к способам и новым промежуточным соединениям для их получения, к фармацевтическим композициям, содержащим их, и к их применению в медицине, особенно в профилактике и лечении гиперлипидемических состояний и связанных с ними заболеваний, таких как атеросклероз.Международная заявка была опубликована вместе с отчетом о международном поиске.
EA200000623A 1998-01-10 1999-01-07 Гиполипидемические бензотиазепиновые соединения EA200000623A1 (ru)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB9800428.6A GB9800428D0 (en) 1998-01-10 1998-01-10 Chemical compounds
PCT/EP1999/000021 WO1999035135A1 (en) 1998-01-10 1999-01-07 Hypolipidemic benzothiazepine compounds

Publications (1)

Publication Number Publication Date
EA200000623A1 true EA200000623A1 (ru) 2001-04-23

Family

ID=10825042

Family Applications (1)

Application Number Title Priority Date Filing Date
EA200000623A EA200000623A1 (ru) 1998-01-10 1999-01-07 Гиполипидемические бензотиазепиновые соединения

Country Status (27)

Country Link
US (1) US6465451B1 (ru)
EP (1) EP1045840A1 (ru)
JP (1) JP2002500220A (ru)
KR (1) KR20010033988A (ru)
CN (1) CN1292785A (ru)
AP (1) AP2000001860A0 (ru)
AR (1) AR014261A1 (ru)
AU (1) AU2515599A (ru)
BR (1) BR9906799A (ru)
CA (1) CA2317651A1 (ru)
CO (1) CO4820391A1 (ru)
EA (1) EA200000623A1 (ru)
GB (1) GB9800428D0 (ru)
HR (1) HRP20000468A2 (ru)
HU (1) HUP0201343A3 (ru)
ID (1) ID25495A (ru)
IL (1) IL137040A0 (ru)
IS (1) IS5551A (ru)
MA (1) MA26595A1 (ru)
NO (1) NO20003514L (ru)
NZ (1) NZ505453A (ru)
PE (1) PE20000179A1 (ru)
PL (1) PL341672A1 (ru)
SK (1) SK10242000A3 (ru)
TR (1) TR200001816T2 (ru)
WO (1) WO1999035135A1 (ru)
ZA (1) ZA9981B (ru)

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Publication number Priority date Publication date Assignee Title
RU2817535C2 (ru) * 2019-02-06 2024-04-16 Альбирео Аб Соединения бензотиазепина и их применение в качестве модуляторов желчных кислот

Also Published As

Publication number Publication date
EP1045840A1 (en) 2000-10-25
IL137040A0 (en) 2001-06-14
NO20003514L (no) 2000-09-07
ZA9981B (en) 2000-07-06
PL341672A1 (en) 2001-04-23
JP2002500220A (ja) 2002-01-08
AR014261A1 (es) 2001-02-07
CN1292785A (zh) 2001-04-25
TR200001816T2 (tr) 2000-11-21
AP2000001860A0 (en) 2000-09-30
BR9906799A (pt) 2000-10-10
PE20000179A1 (es) 2000-03-16
IS5551A (is) 2000-06-27
HRP20000468A2 (en) 2000-10-31
CA2317651A1 (en) 1999-07-15
HUP0201343A2 (hu) 2003-06-28
AU2515599A (en) 1999-07-26
CO4820391A1 (es) 1999-07-28
HUP0201343A3 (en) 2003-08-28
US6465451B1 (en) 2002-10-15
GB9800428D0 (en) 1998-03-04
NZ505453A (en) 2002-11-26
SK10242000A3 (sk) 2001-02-12
KR20010033988A (ko) 2001-04-25
ID25495A (id) 2000-10-05
WO1999035135A1 (en) 1999-07-15
MA26595A1 (fr) 2004-12-20
NO20003514D0 (no) 2000-07-07

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