EA199900710A1 - CRYSTAL HYDRATED SODIUM SALT (E) -4,6-DICHLOR-3- (2-OXO-1-phenylpyrrolidine-3-ilidene-methyl) -1H-indol-2-carboxylic acid - Google Patents

CRYSTAL HYDRATED SODIUM SALT (E) -4,6-DICHLOR-3- (2-OXO-1-phenylpyrrolidine-3-ilidene-methyl) -1H-indol-2-carboxylic acid

Info

Publication number
EA199900710A1
EA199900710A1 EA199900710A EA199900710A EA199900710A1 EA 199900710 A1 EA199900710 A1 EA 199900710A1 EA 199900710 A EA199900710 A EA 199900710A EA 199900710 A EA199900710 A EA 199900710A EA 199900710 A1 EA199900710 A1 EA 199900710A1
Authority
EA
Eurasian Patent Office
Prior art keywords
sodium salt
ilidene
phenylpyrrolidine
dichlor
indol
Prior art date
Application number
EA199900710A
Other languages
Russian (ru)
Inventor
Цадео Чимарости
Паоло Мараньи
Original Assignee
ГЛАКСО ВЕЛЛКАМ С.п.А.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by ГЛАКСО ВЕЛЛКАМ С.п.А. filed Critical ГЛАКСО ВЕЛЛКАМ С.п.А.
Publication of EA199900710A1 publication Critical patent/EA199900710A1/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Abstract

Кристаллическая гидратированная форма натриевой соли соединения формулы (I), способы ее получения и ее применение в терапии.Международная заявка была опубликована вместе с отчетом о международном поиске.The hydrated crystalline form of the sodium salt of the compound of formula (I), methods for its preparation and its use in therapy. The international application was published together with an international search report.

EA199900710A 1997-03-05 1998-03-03 CRYSTAL HYDRATED SODIUM SALT (E) -4,6-DICHLOR-3- (2-OXO-1-phenylpyrrolidine-3-ilidene-methyl) -1H-indol-2-carboxylic acid EA199900710A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB9704498.6A GB9704498D0 (en) 1997-03-05 1997-03-05 Chemical compound
PCT/EP1998/001146 WO1998039327A1 (en) 1997-03-05 1998-03-03 Crystalline hydrated sodium salt of (e)-4,6-dichloro-3-(2-oxo-1-phenylpyrrolidin-3-ylidene methyl)-1h-indole-2-carboxylic acid

Publications (1)

Publication Number Publication Date
EA199900710A1 true EA199900710A1 (en) 2000-04-24

Family

ID=10808697

Family Applications (1)

Application Number Title Priority Date Filing Date
EA199900710A EA199900710A1 (en) 1997-03-05 1998-03-03 CRYSTAL HYDRATED SODIUM SALT (E) -4,6-DICHLOR-3- (2-OXO-1-phenylpyrrolidine-3-ilidene-methyl) -1H-indol-2-carboxylic acid

Country Status (29)

Country Link
EP (1) EP0966463A1 (en)
JP (1) JP2001513796A (en)
KR (1) KR20000075907A (en)
CN (1) CN1249750A (en)
AP (1) AP9901637A0 (en)
AR (1) AR011178A1 (en)
AU (1) AU6825198A (en)
BG (1) BG103779A (en)
BR (1) BR9808305A (en)
CA (1) CA2282851A1 (en)
CO (1) CO4940415A1 (en)
EA (1) EA199900710A1 (en)
EE (1) EE9900387A (en)
GB (1) GB9704498D0 (en)
HR (1) HRP980114A2 (en)
HU (1) HUP0002109A2 (en)
ID (1) ID24207A (en)
IL (1) IL131489A0 (en)
IS (1) IS5166A (en)
NO (1) NO994303L (en)
NZ (1) NZ337315A (en)
OA (1) OA11154A (en)
PE (1) PE51399A1 (en)
PL (1) PL335652A1 (en)
SK (1) SK119699A3 (en)
TR (1) TR199902117T2 (en)
WO (1) WO1998039327A1 (en)
YU (1) YU43499A (en)
ZA (1) ZA981791B (en)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9704499D0 (en) * 1997-03-05 1997-04-23 Glaxo Wellcome Spa Method of manufacture
GB9825988D0 (en) * 1998-11-27 1999-01-20 Pfizer Ltd Indole derivatives
GB9915231D0 (en) 1999-06-29 1999-09-01 Pfizer Ltd Pharmaceutical complex
US9737531B2 (en) 2012-07-12 2017-08-22 Glytech, Llc Composition and method for treatment of depression and psychosis in humans
MX2019015120A (en) 2017-06-12 2022-07-14 Glytech Llc Treatment of depression with nmda antagonists and d2/5ht2a or selective 5ht2a antagonists.

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9321221D0 (en) * 1993-10-14 1993-12-01 Glaxo Spa Heterocyclic compounds

Also Published As

Publication number Publication date
BR9808305A (en) 2000-05-16
YU43499A (en) 2000-12-28
EE9900387A (en) 2000-04-17
OA11154A (en) 2003-04-16
PL335652A1 (en) 2000-05-08
PE51399A1 (en) 1999-06-07
ZA981791B (en) 1999-09-03
CO4940415A1 (en) 2000-07-24
TR199902117T2 (en) 2000-03-21
AU6825198A (en) 1998-09-22
NO994303L (en) 1999-11-03
IL131489A0 (en) 2001-01-28
EP0966463A1 (en) 1999-12-29
KR20000075907A (en) 2000-12-26
NZ337315A (en) 2001-02-23
ID24207A (en) 2000-07-13
JP2001513796A (en) 2001-09-04
GB9704498D0 (en) 1997-04-23
AP9901637A0 (en) 1999-09-30
WO1998039327A1 (en) 1998-09-11
HRP980114A2 (en) 1998-12-31
NO994303D0 (en) 1999-09-03
CA2282851A1 (en) 1998-09-11
HUP0002109A2 (en) 2001-04-28
AR011178A1 (en) 2000-08-02
BG103779A (en) 2000-06-30
IS5166A (en) 1999-08-27
SK119699A3 (en) 2000-05-16
CN1249750A (en) 2000-04-05

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