YU43499A - Crystalline hydrated sodium salt of (e)-4,6-dichloro-3- (2-oxo-1-phenylpyrrolidin-3-ylidene methyl)-1h-indole-2- carboxylic acid - Google Patents

Crystalline hydrated sodium salt of (e)-4,6-dichloro-3- (2-oxo-1-phenylpyrrolidin-3-ylidene methyl)-1h-indole-2- carboxylic acid

Info

Publication number
YU43499A
YU43499A YU43499A YU43499A YU43499A YU 43499 A YU43499 A YU 43499A YU 43499 A YU43499 A YU 43499A YU 43499 A YU43499 A YU 43499A YU 43499 A YU43499 A YU 43499A
Authority
YU
Yugoslavia
Prior art keywords
sodium salt
phenylpyrrolidin
indole
dichloro
oxo
Prior art date
Application number
YU43499A
Other languages
Serbo-Croatian (sh)
Inventor
Zadeo Cimarosti
Paolo Maragni
Original Assignee
Glaxo Wellcome S.P.A.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Glaxo Wellcome S.P.A. filed Critical Glaxo Wellcome S.P.A.
Publication of YU43499A publication Critical patent/YU43499A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Abstract

Kristalna hidratovana natrijumova so (E)-4,6-dihloro-3-(2-okso-1-fenilpirolidin-3-iliden metil)-1h-indol-2- karboksilne kiseline Ovaj pronalazak odnosi se na natrijumovu so jedinjenja formule (1), na postupak za njeno pripremanje, i na njenu primenu u terapiji.The present invention relates to the sodium salt of a compound of formula (1) ), on the procedure for its preparation, and on its application in therapy.

YU43499A 1997-03-05 1998-03-03 Crystalline hydrated sodium salt of (e)-4,6-dichloro-3- (2-oxo-1-phenylpyrrolidin-3-ylidene methyl)-1h-indole-2- carboxylic acid YU43499A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GBGB9704498.6A GB9704498D0 (en) 1997-03-05 1997-03-05 Chemical compound

Publications (1)

Publication Number Publication Date
YU43499A true YU43499A (en) 2000-12-28

Family

ID=10808697

Family Applications (1)

Application Number Title Priority Date Filing Date
YU43499A YU43499A (en) 1997-03-05 1998-03-03 Crystalline hydrated sodium salt of (e)-4,6-dichloro-3- (2-oxo-1-phenylpyrrolidin-3-ylidene methyl)-1h-indole-2- carboxylic acid

Country Status (29)

Country Link
EP (1) EP0966463A1 (en)
JP (1) JP2001513796A (en)
KR (1) KR20000075907A (en)
CN (1) CN1249750A (en)
AP (1) AP9901637A0 (en)
AR (1) AR011178A1 (en)
AU (1) AU6825198A (en)
BG (1) BG103779A (en)
BR (1) BR9808305A (en)
CA (1) CA2282851A1 (en)
CO (1) CO4940415A1 (en)
EA (1) EA199900710A1 (en)
EE (1) EE9900387A (en)
GB (1) GB9704498D0 (en)
HR (1) HRP980114A2 (en)
HU (1) HUP0002109A2 (en)
ID (1) ID24207A (en)
IL (1) IL131489A0 (en)
IS (1) IS5166A (en)
NO (1) NO994303L (en)
NZ (1) NZ337315A (en)
OA (1) OA11154A (en)
PE (1) PE51399A1 (en)
PL (1) PL335652A1 (en)
SK (1) SK119699A3 (en)
TR (1) TR199902117T2 (en)
WO (1) WO1998039327A1 (en)
YU (1) YU43499A (en)
ZA (1) ZA981791B (en)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9704499D0 (en) * 1997-03-05 1997-04-23 Glaxo Wellcome Spa Method of manufacture
GB9825988D0 (en) * 1998-11-27 1999-01-20 Pfizer Ltd Indole derivatives
GB9915231D0 (en) 1999-06-29 1999-09-01 Pfizer Ltd Pharmaceutical complex
US9737531B2 (en) 2012-07-12 2017-08-22 Glytech, Llc Composition and method for treatment of depression and psychosis in humans
CA3067162A1 (en) 2017-06-12 2018-12-20 Glytech Llc. Treatment of depression with nmda antagonists and d2/5ht2a or selective 5ht2a antagonists

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9321221D0 (en) * 1993-10-14 1993-12-01 Glaxo Spa Heterocyclic compounds

Also Published As

Publication number Publication date
WO1998039327A1 (en) 1998-09-11
HUP0002109A2 (en) 2001-04-28
OA11154A (en) 2003-04-16
CA2282851A1 (en) 1998-09-11
IL131489A0 (en) 2001-01-28
BR9808305A (en) 2000-05-16
AU6825198A (en) 1998-09-22
NO994303D0 (en) 1999-09-03
EE9900387A (en) 2000-04-17
AP9901637A0 (en) 1999-09-30
EP0966463A1 (en) 1999-12-29
PE51399A1 (en) 1999-06-07
PL335652A1 (en) 2000-05-08
ID24207A (en) 2000-07-13
HRP980114A2 (en) 1998-12-31
KR20000075907A (en) 2000-12-26
CN1249750A (en) 2000-04-05
BG103779A (en) 2000-06-30
SK119699A3 (en) 2000-05-16
AR011178A1 (en) 2000-08-02
ZA981791B (en) 1999-09-03
JP2001513796A (en) 2001-09-04
NO994303L (en) 1999-11-03
IS5166A (en) 1999-08-27
TR199902117T2 (en) 2000-03-21
GB9704498D0 (en) 1997-04-23
CO4940415A1 (en) 2000-07-24
NZ337315A (en) 2001-02-23
EA199900710A1 (en) 2000-04-24

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