BR9808305A - Crystalline hydrated form, process for the preparation of hydrated crystalline form, pharmaceutical composition, process for treating a mammal, and process for treating or preventing pain. - Google Patents

Crystalline hydrated form, process for the preparation of hydrated crystalline form, pharmaceutical composition, process for treating a mammal, and process for treating or preventing pain.

Info

Publication number
BR9808305A
BR9808305A BR9808305-8A BR9808305A BR9808305A BR 9808305 A BR9808305 A BR 9808305A BR 9808305 A BR9808305 A BR 9808305A BR 9808305 A BR9808305 A BR 9808305A
Authority
BR
Brazil
Prior art keywords
treating
hydrated
crystalline
preparation
pharmaceutical composition
Prior art date
Application number
BR9808305-8A
Other languages
Portuguese (pt)
Inventor
Zadeo Cimarosti
Paolo Maragni
Original Assignee
Glaxo Wellcome Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Glaxo Wellcome Spa filed Critical Glaxo Wellcome Spa
Publication of BR9808305A publication Critical patent/BR9808305A/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D403/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/06Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/04Centrally acting analgesics, e.g. opioids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Neurosurgery (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Biomedical Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Neurology (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychiatry (AREA)
  • Pain & Pain Management (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Indole Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pyrrole Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

"FORMA HIDRATADA CRISTALINA, PROCESSO PARA A PREPARAçãO DA FORMA HIDRATADA CRISTALINA, COMPOSIçãO FARMACêUTICA, PROCESSO DE TRATAMENTO DE UM MAMìFERO, E, PROCESSO DE TRATAMENTO OU DE PREVENçãO DE DOR". Uma forma cristalina hidratada de sal de sódio de composto de fórmula (I), processo para sua preparação e seu uso em terapia."CRYSTALLINE HYDRATED FORM, PROCESS FOR THE PREPARATION OF CRYSTALLINE HYDRATED FORM, PHARMACEUTICAL COMPOSITION, TREATMENT PROCESS FOR A MAMMALIAN, AND PROCESS OF TREATMENT OR PREVENTION OF PAIN". A hydrated crystalline form of the sodium salt of the compound of formula (I), process for its preparation and use in therapy.

BR9808305-8A 1997-03-05 1998-03-03 Crystalline hydrated form, process for the preparation of hydrated crystalline form, pharmaceutical composition, process for treating a mammal, and process for treating or preventing pain. BR9808305A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB9704498.6A GB9704498D0 (en) 1997-03-05 1997-03-05 Chemical compound
PCT/EP1998/001146 WO1998039327A1 (en) 1997-03-05 1998-03-03 Crystalline hydrated sodium salt of (e)-4,6-dichloro-3-(2-oxo-1-phenylpyrrolidin-3-ylidene methyl)-1h-indole-2-carboxylic acid

Publications (1)

Publication Number Publication Date
BR9808305A true BR9808305A (en) 2000-05-16

Family

ID=10808697

Family Applications (1)

Application Number Title Priority Date Filing Date
BR9808305-8A BR9808305A (en) 1997-03-05 1998-03-03 Crystalline hydrated form, process for the preparation of hydrated crystalline form, pharmaceutical composition, process for treating a mammal, and process for treating or preventing pain.

Country Status (29)

Country Link
EP (1) EP0966463A1 (en)
JP (1) JP2001513796A (en)
KR (1) KR20000075907A (en)
CN (1) CN1249750A (en)
AP (1) AP9901637A0 (en)
AR (1) AR011178A1 (en)
AU (1) AU6825198A (en)
BG (1) BG103779A (en)
BR (1) BR9808305A (en)
CA (1) CA2282851A1 (en)
CO (1) CO4940415A1 (en)
EA (1) EA199900710A1 (en)
EE (1) EE9900387A (en)
GB (1) GB9704498D0 (en)
HR (1) HRP980114A2 (en)
HU (1) HUP0002109A2 (en)
ID (1) ID24207A (en)
IL (1) IL131489A0 (en)
IS (1) IS5166A (en)
NO (1) NO994303L (en)
NZ (1) NZ337315A (en)
OA (1) OA11154A (en)
PE (1) PE51399A1 (en)
PL (1) PL335652A1 (en)
SK (1) SK119699A3 (en)
TR (1) TR199902117T2 (en)
WO (1) WO1998039327A1 (en)
YU (1) YU43499A (en)
ZA (1) ZA981791B (en)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9704499D0 (en) * 1997-03-05 1997-04-23 Glaxo Wellcome Spa Method of manufacture
GB9825988D0 (en) * 1998-11-27 1999-01-20 Pfizer Ltd Indole derivatives
GB9915231D0 (en) 1999-06-29 1999-09-01 Pfizer Ltd Pharmaceutical complex
US9737531B2 (en) 2012-07-12 2017-08-22 Glytech, Llc Composition and method for treatment of depression and psychosis in humans
WO2018229744A1 (en) 2017-06-12 2018-12-20 Glytech Llc. Treatment of depression with nmda antagonists and d2/5ht2a or selective 5ht2a antagonists

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9321221D0 (en) * 1993-10-14 1993-12-01 Glaxo Spa Heterocyclic compounds

Also Published As

Publication number Publication date
AP9901637A0 (en) 1999-09-30
AU6825198A (en) 1998-09-22
EE9900387A (en) 2000-04-17
HUP0002109A2 (en) 2001-04-28
CN1249750A (en) 2000-04-05
BG103779A (en) 2000-06-30
PE51399A1 (en) 1999-06-07
GB9704498D0 (en) 1997-04-23
CA2282851A1 (en) 1998-09-11
ID24207A (en) 2000-07-13
SK119699A3 (en) 2000-05-16
AR011178A1 (en) 2000-08-02
CO4940415A1 (en) 2000-07-24
IL131489A0 (en) 2001-01-28
KR20000075907A (en) 2000-12-26
YU43499A (en) 2000-12-28
NO994303L (en) 1999-11-03
IS5166A (en) 1999-08-27
PL335652A1 (en) 2000-05-08
WO1998039327A1 (en) 1998-09-11
OA11154A (en) 2003-04-16
HRP980114A2 (en) 1998-12-31
NO994303D0 (en) 1999-09-03
EA199900710A1 (en) 2000-04-24
ZA981791B (en) 1999-09-03
EP0966463A1 (en) 1999-12-29
TR199902117T2 (en) 2000-03-21
JP2001513796A (en) 2001-09-04
NZ337315A (en) 2001-02-23

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Legal Events

Date Code Title Description
FA10 Dismissal: dismissal - article 33 of industrial property law
B11Y Definitive dismissal - extension of time limit for request of examination expired [chapter 11.1.1 patent gazette]