EA038567B1 - Способы лечения аутоиммунных и аллоиммунных расстройств - Google Patents
Способы лечения аутоиммунных и аллоиммунных расстройств Download PDFInfo
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- EA038567B1 EA038567B1 EA201890106A EA201890106A EA038567B1 EA 038567 B1 EA038567 B1 EA 038567B1 EA 201890106 A EA201890106 A EA 201890106A EA 201890106 A EA201890106 A EA 201890106A EA 038567 B1 EA038567 B1 EA 038567B1
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- A61K39/39566—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against immunoglobulins, e.g. anti-idiotypic antibodies
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- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K35/14—Blood; Artificial blood
- A61K35/15—Cells of the myeloid line, e.g. granulocytes, basophils, eosinophils, neutrophils, leucocytes, monocytes, macrophages or mast cells; Myeloid precursor cells; Antigen-presenting cells, e.g. dendritic cells
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- A61K39/39541—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against normal tissues, cells
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
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- C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
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- C—CHEMISTRY; METALLURGY
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- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
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- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
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Landscapes
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- Immunology (AREA)
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- Investigating Or Analysing Biological Materials (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
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| IL (1) | IL256424B2 (enExample) |
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| CN110818798A (zh) | 2012-10-25 | 2020-02-21 | 美国比奥维拉迪维股份有限公司 | 抗补体C1s抗体和其用途 |
| RS63212B1 (sr) | 2012-11-02 | 2022-06-30 | Bioverativ Usa Inc | Antikomplementna c1s antitela i njihove primene |
| HUE061076T2 (hu) | 2015-04-06 | 2023-05-28 | Bioverativ Usa Inc | Humanizált anti-C1s ellenanyagok alkalmazási eljárások |
| SI3448419T1 (sl) * | 2016-04-29 | 2023-10-30 | Pfizer Inc. | Protitelesa interferon beta in njihove uporabe |
| DK3525583T3 (da) | 2016-10-12 | 2025-10-27 | Bioverativ Usa Inc | Anti-c1s-antistoffer og fremgangsmåder til anvendelse deraf |
| EP4640703A2 (en) | 2017-11-14 | 2025-10-29 | Chugai Seiyaku Kabushiki Kaisha | Anti-c1s antibodies and methods of use |
| KR20220016865A9 (ko) | 2019-05-15 | 2022-02-21 | 추가이 세이야쿠 가부시키가이샤 | 항원 결합 분자, 약학 조성물, 및 방법 |
| WO2021075479A1 (en) * | 2019-10-16 | 2021-04-22 | Chugai Seiyaku Kabushiki Kaisha | An antibody, a pharmaceutical composition, and a method |
| EP4193153A1 (en) * | 2020-08-06 | 2023-06-14 | Bioverativ USA Inc. | Inflammatory cytokines and fatigue in subject with a complement mediated disease |
| US11958899B2 (en) | 2021-07-13 | 2024-04-16 | Mabwell Therapeutics Inc. | Anti-C1s antibodies and uses thereof |
Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20040115194A1 (en) * | 2002-09-06 | 2004-06-17 | Yi Wang | Method of treatment of asthma using antibodies to complement component C5 |
| US20040219147A1 (en) * | 2003-01-09 | 2004-11-04 | Leonard Bell | Methods for reducing mortality associated with acute myocardial infarction |
| US20050079174A1 (en) * | 1999-08-23 | 2005-04-14 | Biocrystal, Ltd. | Methods and compositions for immunotherapy of B cell involvement in promotion of a disease condition comprising multiple sclerosis |
| WO2014066744A2 (en) * | 2012-10-25 | 2014-05-01 | True North Therapeutics, Inc. | Anti-complement c1s antibodies and uses thereof |
| US20140127208A1 (en) * | 2012-11-02 | 2014-05-08 | True North Therapeutics, Inc. | Anti-Complement C1s Antibodies and Uses Thereof |
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| WO2009132058A2 (en) * | 2008-04-25 | 2009-10-29 | Zymogenetics, Inc. | Levels of bcma protein expression on b cells and use in diagnostic methods |
| KR20120105405A (ko) * | 2009-06-23 | 2012-09-25 | 알렉시온 파마슈티칼스, 인코포레이티드 | 보체 단백질에 결합하는 이중특이적 항체 |
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Patent Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20050079174A1 (en) * | 1999-08-23 | 2005-04-14 | Biocrystal, Ltd. | Methods and compositions for immunotherapy of B cell involvement in promotion of a disease condition comprising multiple sclerosis |
| US20040115194A1 (en) * | 2002-09-06 | 2004-06-17 | Yi Wang | Method of treatment of asthma using antibodies to complement component C5 |
| US20040219147A1 (en) * | 2003-01-09 | 2004-11-04 | Leonard Bell | Methods for reducing mortality associated with acute myocardial infarction |
| WO2014066744A2 (en) * | 2012-10-25 | 2014-05-01 | True North Therapeutics, Inc. | Anti-complement c1s antibodies and uses thereof |
| US20140127208A1 (en) * | 2012-11-02 | 2014-05-08 | True North Therapeutics, Inc. | Anti-Complement C1s Antibodies and Uses Thereof |
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| AU2022215307B2 (en) | 2025-09-04 |
| US20220249664A1 (en) | 2022-08-11 |
| CA2990662A1 (en) | 2016-12-29 |
| NZ738570A (en) | 2025-05-02 |
| IL256424B1 (en) | 2024-05-01 |
| JP2018526330A (ja) | 2018-09-13 |
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| MX2023002021A (es) | 2023-03-15 |
| IL256424B2 (en) | 2024-09-01 |
| MX2017016835A (es) | 2018-08-01 |
| AU2016282782A1 (en) | 2018-01-18 |
| HK1254030A1 (zh) | 2019-07-12 |
| AU2022215307A1 (en) | 2022-09-08 |
| KR20180020296A (ko) | 2018-02-27 |
| JP6963509B2 (ja) | 2021-11-10 |
| BR112017027578A2 (pt) | 2018-08-28 |
| WO2016210172A1 (en) | 2016-12-29 |
| CN108348600A (zh) | 2018-07-31 |
| EA201890106A1 (ru) | 2018-05-31 |
| EP3313417A4 (en) | 2019-06-12 |
| IL256424A (en) | 2018-02-28 |
| US20180169240A1 (en) | 2018-06-21 |
| US20250295768A1 (en) | 2025-09-25 |
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