EA038567B1 - Способы лечения аутоиммунных и аллоиммунных расстройств - Google Patents
Способы лечения аутоиммунных и аллоиммунных расстройств Download PDFInfo
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- EA038567B1 EA038567B1 EA201890106A EA201890106A EA038567B1 EA 038567 B1 EA038567 B1 EA 038567B1 EA 201890106 A EA201890106 A EA 201890106A EA 201890106 A EA201890106 A EA 201890106A EA 038567 B1 EA038567 B1 EA 038567B1
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Classifications
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- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
- A61K39/39533—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
- A61K39/39566—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against immunoglobulins, e.g. anti-idiotypic antibodies
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- A—HUMAN NECESSITIES
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K35/14—Blood; Artificial blood
- A61K35/15—Cells of the myeloid line, e.g. granulocytes, basophils, eosinophils, neutrophils, leucocytes, monocytes, macrophages or mast cells; Myeloid precursor cells; Antigen-presenting cells, e.g. dendritic cells
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- A—HUMAN NECESSITIES
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
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- A—HUMAN NECESSITIES
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- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
- A61K39/39533—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
- A61K39/39541—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against normal tissues, cells
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
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- A—HUMAN NECESSITIES
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- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
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- C—CHEMISTRY; METALLURGY
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- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/40—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against enzymes
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/42—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against immunoglobulins
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- A—HUMAN NECESSITIES
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- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
- C07K2317/24—Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
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- C—CHEMISTRY; METALLURGY
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- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
- C07K2317/567—Framework region [FR]
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Immunology (AREA)
- Life Sciences & Earth Sciences (AREA)
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- Engineering & Computer Science (AREA)
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- Microbiology (AREA)
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- Proteomics, Peptides & Aminoacids (AREA)
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- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
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- Virology (AREA)
- Zoology (AREA)
- Transplantation (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
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| US201562185362P | 2015-06-26 | 2015-06-26 | |
| PCT/US2016/039087 WO2016210172A1 (en) | 2015-06-26 | 2016-06-23 | Methods of treating autoimmune and alloimmune disorders |
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| EA201890106A1 EA201890106A1 (ru) | 2018-05-31 |
| EA038567B1 true EA038567B1 (ru) | 2021-09-15 |
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| EA201890106A EA038567B1 (ru) | 2015-06-26 | 2016-06-23 | Способы лечения аутоиммунных и аллоиммунных расстройств |
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| EP (1) | EP3313417A4 (OSRAM) |
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| KR (1) | KR20180020296A (OSRAM) |
| CN (1) | CN108348600A (OSRAM) |
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| EA (1) | EA038567B1 (OSRAM) |
| HK (1) | HK1254030A1 (OSRAM) |
| IL (1) | IL256424B2 (OSRAM) |
| MX (2) | MX2017016835A (OSRAM) |
| WO (1) | WO2016210172A1 (OSRAM) |
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| EP3722320A3 (en) | 2012-10-25 | 2020-12-30 | Bioverativ USA Inc. | Anti-complement c1s antibodies and uses thereof |
| GB2509260B (en) | 2012-11-02 | 2016-05-04 | True North Therapeutics Inc | Anti-complement C1s antibodies and uses thereof |
| HK1259251A1 (zh) | 2015-04-06 | 2019-11-29 | Bioverativ Usa Inc. | 人源化抗c1s抗体及其使用方法 |
| IL262244B2 (en) | 2016-04-29 | 2024-01-01 | Pfizer | Antibodies against beta interferon and their use |
| MY198182A (en) | 2016-10-12 | 2023-08-09 | Bioverativ Usa Inc | Anti-C1s Antibodies and Methods of use Thereof |
| EP3710589A4 (en) | 2017-11-14 | 2021-11-10 | Chugai Seiyaku Kabushiki Kaisha | ANTI-C1S ANTIBODIES AND METHOD OF USING |
| CA3137649A1 (en) | 2019-05-15 | 2020-11-19 | Chugai Seiyaku Kabushiki Kaisha | An antigen-binding molecule, a pharmaceutical composition, and a method |
| JP7628796B2 (ja) * | 2019-10-16 | 2025-02-12 | 中外製薬株式会社 | 抗体、薬学的組成物、および方法 |
| EP4193153A1 (en) * | 2020-08-06 | 2023-06-14 | Bioverativ USA Inc. | Inflammatory cytokines and fatigue in subject with a complement mediated disease |
| EP4337332A2 (en) | 2021-07-13 | 2024-03-20 | Mabwell Therapeutics Inc. | Anti-c1s antibodies and uses thereof |
Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20040115194A1 (en) * | 2002-09-06 | 2004-06-17 | Yi Wang | Method of treatment of asthma using antibodies to complement component C5 |
| US20040219147A1 (en) * | 2003-01-09 | 2004-11-04 | Leonard Bell | Methods for reducing mortality associated with acute myocardial infarction |
| US20050079174A1 (en) * | 1999-08-23 | 2005-04-14 | Biocrystal, Ltd. | Methods and compositions for immunotherapy of B cell involvement in promotion of a disease condition comprising multiple sclerosis |
| WO2014066744A2 (en) * | 2012-10-25 | 2014-05-01 | True North Therapeutics, Inc. | Anti-complement c1s antibodies and uses thereof |
| US20140127208A1 (en) * | 2012-11-02 | 2014-05-08 | True North Therapeutics, Inc. | Anti-Complement C1s Antibodies and Uses Thereof |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP2283355A2 (en) * | 2008-04-25 | 2011-02-16 | Zymogenetics, Inc. | Levels of bcma protein expression on b cells and use in diagnostic methods |
| US20110002931A1 (en) * | 2009-06-23 | 2011-01-06 | Alexion Pharmaceuticals, Inc. | Bispecific antibodies that bind to complement proteins |
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2016
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- 2016-06-23 KR KR1020187002518A patent/KR20180020296A/ko active Pending
- 2016-06-23 US US15/739,622 patent/US20180169240A1/en not_active Abandoned
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- 2016-06-23 WO PCT/US2016/039087 patent/WO2016210172A1/en not_active Ceased
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- 2016-06-23 EA EA201890106A patent/EA038567B1/ru unknown
- 2016-06-23 IL IL256424A patent/IL256424B2/en unknown
- 2016-06-23 HK HK18112887.1A patent/HK1254030A1/zh unknown
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2021
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2024
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Patent Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20050079174A1 (en) * | 1999-08-23 | 2005-04-14 | Biocrystal, Ltd. | Methods and compositions for immunotherapy of B cell involvement in promotion of a disease condition comprising multiple sclerosis |
| US20040115194A1 (en) * | 2002-09-06 | 2004-06-17 | Yi Wang | Method of treatment of asthma using antibodies to complement component C5 |
| US20040219147A1 (en) * | 2003-01-09 | 2004-11-04 | Leonard Bell | Methods for reducing mortality associated with acute myocardial infarction |
| WO2014066744A2 (en) * | 2012-10-25 | 2014-05-01 | True North Therapeutics, Inc. | Anti-complement c1s antibodies and uses thereof |
| US20140127208A1 (en) * | 2012-11-02 | 2014-05-08 | True North Therapeutics, Inc. | Anti-Complement C1s Antibodies and Uses Thereof |
Also Published As
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| US20250295768A1 (en) | 2025-09-25 |
| MX2023002021A (es) | 2023-03-15 |
| HK1254030A1 (zh) | 2019-07-12 |
| US20220249664A1 (en) | 2022-08-11 |
| AU2022215307A1 (en) | 2022-09-08 |
| CN108348600A (zh) | 2018-07-31 |
| EP3313417A4 (en) | 2019-06-12 |
| NZ738570A (en) | 2025-05-02 |
| IL256424A (en) | 2018-02-28 |
| WO2016210172A1 (en) | 2016-12-29 |
| AU2022215307B2 (en) | 2025-09-04 |
| IL256424B1 (en) | 2024-05-01 |
| KR20180020296A (ko) | 2018-02-27 |
| JP6963509B2 (ja) | 2021-11-10 |
| CA2990662A1 (en) | 2016-12-29 |
| AU2016282782A1 (en) | 2018-01-18 |
| BR112017027578A2 (pt) | 2018-08-28 |
| US20180169240A1 (en) | 2018-06-21 |
| JP2018526330A (ja) | 2018-09-13 |
| EA201890106A1 (ru) | 2018-05-31 |
| IL256424B2 (en) | 2024-09-01 |
| EP3313417A1 (en) | 2018-05-02 |
| MX2017016835A (es) | 2018-08-01 |
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