EA033318B1 - Method of producing a bioactive coating with antibacterial effect - Google Patents

Method of producing a bioactive coating with antibacterial effect

Info

Publication number
EA033318B1
EA033318B1 EA201700215A EA201700215A EA033318B1 EA 033318 B1 EA033318 B1 EA 033318B1 EA 201700215 A EA201700215 A EA 201700215A EA 201700215 A EA201700215 A EA 201700215A EA 033318 B1 EA033318 B1 EA 033318B1
Authority
EA
Eurasian Patent Office
Prior art keywords
implants
antibacterial effect
additive
bioactive
machining
Prior art date
Application number
EA201700215A
Other languages
Russian (ru)
Other versions
EA201700215A1 (en
Inventor
Евгений Александрович Левашов
Александр Евгеньевич Кудряшов
Евгения Игоревна Замулаева
Дмитрий Владимирович Штанский
Юрий Сергеевич Погожев
Артем Юрьевич Потанин
Наталия Владимировна Швындина
Original Assignee
Федеральное государственное автономное образовательное учреждение высшего образования "Национальный исследовательский технологический университет "МИСиС"
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from RU2014142170/15A external-priority patent/RU2580627C1/en
Priority claimed from RU2014142171/15A external-priority patent/RU2580628C1/en
Application filed by Федеральное государственное автономное образовательное учреждение высшего образования "Национальный исследовательский технологический университет "МИСиС" filed Critical Федеральное государственное автономное образовательное учреждение высшего образования "Национальный исследовательский технологический университет "МИСиС"
Publication of EA201700215A1 publication Critical patent/EA201700215A1/en
Publication of EA033318B1 publication Critical patent/EA033318B1/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/28—Materials for coating prostheses
    • A61L27/30—Inorganic materials
    • A61L27/306—Other specific inorganic materials not covered by A61L27/303 - A61L27/32
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/02—Inorganic materials
    • A61L27/04—Metals or alloys
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/28—Materials for coating prostheses
    • A61L27/30—Inorganic materials
    • A61L27/32—Phosphorus-containing materials, e.g. apatite
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L27/54—Biologically active materials, e.g. therapeutic substances
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/10—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices containing or releasing inorganic materials
    • A61L2300/102—Metals or metal compounds, e.g. salts such as bicarbonates, carbonates, oxides, zeolites, silicates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/10—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices containing or releasing inorganic materials
    • A61L2300/102—Metals or metal compounds, e.g. salts such as bicarbonates, carbonates, oxides, zeolites, silicates
    • A61L2300/104—Silver, e.g. silver sulfadiazine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/40—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
    • A61L2300/404—Biocides, antimicrobial agents, antiseptic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2420/00—Materials or methods for coatings medical devices
    • A61L2420/06—Coatings containing a mixture of two or more compounds

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Transplantation (AREA)
  • Epidemiology (AREA)
  • Dermatology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Veterinary Medicine (AREA)
  • Inorganic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Materials For Medical Uses (AREA)
  • Dental Preparations (AREA)
  • Dental Prosthetics (AREA)

Abstract

The invention relates to surface machining of medical purpose metals and their alloys and can be used for the production of implants for the replacement of damaged bone tissue fragments including, for example, orthopedic and dental implants, maxillofacial and spinal column surgery implants, artificial joints, clamps etc. The technical result achieved by the provided method is the provision of implants made from special medical purpose alloys with continuous bioactive coatings with antibacterial effect and high adhesion strength to substrate (critical load more than 100 N), high wear resistance and controlled roughness. The technical result is achieved as follows. The method of obtaining bioactive coatings with antibacterial effect comprises electrospark machining of the electrical conductive substrate surface with the processing electrode of the following compositions (wt.%): bioactive additive - 5-40, antibacterial metallic additive - 0.5-5, biocompatible additive of metal or a refractory compound - balance. Electrospark machining is carried out under the following conditions: 100≤N≤10000, 10≤f≤100000, 0,01≤v≤0.6, where Nis the power of a unit pulse discharge, W; f is the frequency of pulse discharges, Hz; v is the linear speed of the processing electrode, m/min.
EA201700215A 2014-10-21 2015-01-30 Method of producing a bioactive coating with antibacterial effect EA033318B1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
RU2014142170/15A RU2580627C1 (en) 2014-10-21 2014-10-21 Method for producing bioactive coating with antibacterial effect
RU2014142171/15A RU2580628C1 (en) 2014-10-21 2014-10-21 Method for producing bioactive coating with antibacterial effect
PCT/RU2015/000055 WO2016064296A1 (en) 2014-10-21 2015-01-30 Method of producing the bioactive coating with antibacterial effect

Publications (2)

Publication Number Publication Date
EA201700215A1 EA201700215A1 (en) 2017-08-31
EA033318B1 true EA033318B1 (en) 2019-09-30

Family

ID=55761216

Family Applications (1)

Application Number Title Priority Date Filing Date
EA201700215A EA033318B1 (en) 2014-10-21 2015-01-30 Method of producing a bioactive coating with antibacterial effect

Country Status (2)

Country Link
EA (1) EA033318B1 (en)
WO (1) WO2016064296A1 (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN115120783A (en) * 2022-06-29 2022-09-30 湖南华翔医疗科技有限公司 Porous titanium-based antibacterial active material, and preparation method and application thereof

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2524654C1 (en) * 2013-06-21 2014-07-27 Федеральное государственное автономное образовательное учреждение высшего профессионального образования "Национальный исследовательский технологический университет "МИСиС" Multicomponent bioactive nanocomposite coating with antibacterial effect

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2524654C1 (en) * 2013-06-21 2014-07-27 Федеральное государственное автономное образовательное учреждение высшего профессионального образования "Национальный исследовательский технологический университет "МИСиС" Multicomponent bioactive nanocomposite coating with antibacterial effect

Non-Patent Citations (4)

* Cited by examiner, † Cited by third party
Title
JESWANI M.L. Electrical discharge machining in distilled water. Wear, 1981, Vol. 72, p. 81-88 *
ORHAN SAHIN et al. Mass Transfer - Advanced Aspects. Chapter 21 - Electrospark Deposition: Mass Transfer, July 2011, p. 481-504 *
SPADLO S. et al. The superficial layer quality alloying by electro spark deposition method. Journal of Achievements in Materials and Manufacturing Engineering. May 2014, Vol. 64, № 1, p. 39-44 *
ZHUKOVA Yu. S. Poluchenie i issledovanie svoystv sverhuprugih splavov Ti-Nb-Ta, Ti-Nb-Zr meditsinskogo naznacheniya. Avtoreferat dissertatsii na soiskanie uchenoy stepeni kandidata himicheskih nauk, 2013 *

Also Published As

Publication number Publication date
EA201700215A1 (en) 2017-08-31
WO2016064296A1 (en) 2016-04-28

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Legal Events

Date Code Title Description
MM4A Lapse of a eurasian patent due to non-payment of renewal fees within the time limit in the following designated state(s)

Designated state(s): AZ KG TJ TM RU