EA033083B1 - Циклические соединения - Google Patents
Циклические соединенияInfo
- Publication number
- EA033083B1 EA033083B1 EA201792469A EA201792469A EA033083B1 EA 033083 B1 EA033083 B1 EA 033083B1 EA 201792469 A EA201792469 A EA 201792469A EA 201792469 A EA201792469 A EA 201792469A EA 033083 B1 EA033083 B1 EA 033083B1
- Authority
- EA
- Eurasian Patent Office
- Prior art keywords
- chemotherapy
- relates
- present
- cyclic compounds
- induced
- Prior art date
Links
- 150000001923 cyclic compounds Chemical class 0.000 title 1
- 206010063837 Reperfusion injury Diseases 0.000 abstract 2
- 102000008233 Toll-Like Receptor 4 Human genes 0.000 abstract 2
- 108010060804 Toll-Like Receptor 4 Proteins 0.000 abstract 2
- 208000015114 central nervous system disease Diseases 0.000 abstract 2
- 238000002512 chemotherapy Methods 0.000 abstract 2
- 150000001875 compounds Chemical class 0.000 abstract 2
- 208000012947 ischemia reperfusion injury Diseases 0.000 abstract 2
- 206010067125 Liver injury Diseases 0.000 abstract 1
- 231100000753 hepatic injury Toxicity 0.000 abstract 1
- 208000027866 inflammatory disease Diseases 0.000 abstract 1
- 230000002401 inhibitory effect Effects 0.000 abstract 1
- 208000004296 neuralgia Diseases 0.000 abstract 1
- 208000021722 neuropathic pain Diseases 0.000 abstract 1
- 208000033808 peripheral neuropathy Diseases 0.000 abstract 1
- 230000003449 preventive effect Effects 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 229940126585 therapeutic drug Drugs 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D317/00—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
- C07D317/08—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
- C07D317/72—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 spiro-condensed with carbocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C317/00—Sulfones; Sulfoxides
- C07C317/12—Sulfones; Sulfoxides having sulfone or sulfoxide groups bound to carbon atoms of rings other than six-membered aromatic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C317/00—Sulfones; Sulfoxides
- C07C317/44—Sulfones; Sulfoxides having sulfone or sulfoxide groups and carboxyl groups bound to the same carbon skeleton
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C317/00—Sulfones; Sulfoxides
- C07C317/44—Sulfones; Sulfoxides having sulfone or sulfoxide groups and carboxyl groups bound to the same carbon skeleton
- C07C317/46—Sulfones; Sulfoxides having sulfone or sulfoxide groups and carboxyl groups bound to the same carbon skeleton the carbon skeleton being further substituted by singly-bound oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D309/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings
- C07D309/16—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
- C07D309/28—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2601/00—Systems containing only non-condensed rings
- C07C2601/12—Systems containing only non-condensed rings with a six-membered ring
- C07C2601/16—Systems containing only non-condensed rings with a six-membered ring the ring being unsaturated
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2602/00—Systems containing two condensed rings
- C07C2602/02—Systems containing two condensed rings the rings having only two atoms in common
- C07C2602/04—One of the condensed rings being a six-membered aromatic ring
- C07C2602/08—One of the condensed rings being a six-membered aromatic ring the other ring being five-membered, e.g. indane
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Immunology (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Rheumatology (AREA)
- Pain & Pain Management (AREA)
- Gastroenterology & Hepatology (AREA)
- Urology & Nephrology (AREA)
- Vascular Medicine (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Heterocyclic Compounds That Contain Two Or More Ring Oxygen Atoms (AREA)
- Pyrane Compounds (AREA)
- Pyridine Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2015095817 | 2015-05-08 | ||
| PCT/JP2016/064204 WO2016182036A1 (en) | 2015-05-08 | 2016-05-06 | Cyclic compounds |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| EA201792469A1 EA201792469A1 (ru) | 2018-06-29 |
| EA033083B1 true EA033083B1 (ru) | 2019-08-30 |
Family
ID=56132991
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| EA201792469A EA033083B1 (ru) | 2015-05-08 | 2016-05-06 | Циклические соединения |
Country Status (11)
| Country | Link |
|---|---|
| US (3) | US9611244B2 (cg-RX-API-DMAC10.html) |
| EP (1) | EP3294706B1 (cg-RX-API-DMAC10.html) |
| JP (1) | JP6718884B2 (cg-RX-API-DMAC10.html) |
| CN (1) | CN107835800B (cg-RX-API-DMAC10.html) |
| AR (1) | AR104539A1 (cg-RX-API-DMAC10.html) |
| CA (1) | CA2985325C (cg-RX-API-DMAC10.html) |
| EA (1) | EA033083B1 (cg-RX-API-DMAC10.html) |
| ES (1) | ES2772703T3 (cg-RX-API-DMAC10.html) |
| TW (1) | TW201704206A (cg-RX-API-DMAC10.html) |
| UY (1) | UY36675A (cg-RX-API-DMAC10.html) |
| WO (1) | WO2016182036A1 (cg-RX-API-DMAC10.html) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US9611244B2 (en) * | 2015-05-08 | 2017-04-04 | Takeda Pharmaceutical Company Limited | Cyclic compounds |
| RU2742337C2 (ru) | 2016-09-09 | 2021-02-04 | Такеда Фармасьютикал Компани Лимитед | Циклическое соединение |
| FR3095755A1 (fr) * | 2019-05-10 | 2020-11-13 | Balmes Transplantation | Nouveaux médicaments cytoprotecteurs |
| CN114425054A (zh) * | 2022-01-20 | 2022-05-03 | 中国人民解放军军事科学院军事医学研究院 | 一种蛋白酶体抑制剂Bortezomib在抗辐射损伤中的用途 |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1495756A1 (en) * | 2002-04-08 | 2005-01-12 | Takeda Chemical Industries, Ltd. | Severe sepsis preventive therapeutic agent |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DK1063228T5 (da) | 1998-03-09 | 2009-06-15 | Takeda Pharmaceutical | Cycloalkenderivater, fremgangsmåde til fremstilling deraf og anvendelse deraf |
| WO2001010826A1 (en) | 1999-08-06 | 2001-02-15 | Takeda Chemical Industries, Ltd. | Substituted aromatic-ring compounds, process for producing the same, and use |
| JP2004002370A (ja) * | 2002-04-08 | 2004-01-08 | Takeda Chem Ind Ltd | 重症セプシス予防治療剤 |
| US7935835B2 (en) * | 2005-09-14 | 2011-05-03 | Daiichi Sankyo Company, Limited | Substituted cycloalkene derivative |
| JP2008260760A (ja) * | 2007-03-12 | 2008-10-30 | Daiichi Sankyo Co Ltd | 置換シクロアルケン誘導体を含有する医薬組成物 |
| US20100135908A1 (en) * | 2008-12-02 | 2010-06-03 | Searete Llc, A Limited Liability Corporation Of The State Of Delaware | Delivery devices for modulating inflammation |
| SG10201503402XA (en) | 2010-01-27 | 2015-06-29 | Takeda Pharmaceutical | Compounds for suppressing a peripheral nerve disorder induced by an anti-cancer agent |
| US9611244B2 (en) * | 2015-05-08 | 2017-04-04 | Takeda Pharmaceutical Company Limited | Cyclic compounds |
-
2016
- 2016-05-06 US US15/148,210 patent/US9611244B2/en active Active
- 2016-05-06 CN CN201680040064.1A patent/CN107835800B/zh active Active
- 2016-05-06 JP JP2017555812A patent/JP6718884B2/ja active Active
- 2016-05-06 WO PCT/JP2016/064204 patent/WO2016182036A1/en not_active Ceased
- 2016-05-06 UY UY0001036675A patent/UY36675A/es not_active Application Discontinuation
- 2016-05-06 CA CA2985325A patent/CA2985325C/en active Active
- 2016-05-06 TW TW105114092A patent/TW201704206A/zh unknown
- 2016-05-06 ES ES16729646T patent/ES2772703T3/es active Active
- 2016-05-06 EP EP16729646.6A patent/EP3294706B1/en active Active
- 2016-05-06 AR ARP160101293A patent/AR104539A1/es unknown
- 2016-05-06 EA EA201792469A patent/EA033083B1/ru not_active IP Right Cessation
- 2016-06-07 US US15/175,292 patent/US9533966B2/en active Active
- 2016-11-21 US US15/356,906 patent/US9828357B2/en active Active
Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1495756A1 (en) * | 2002-04-08 | 2005-01-12 | Takeda Chemical Industries, Ltd. | Severe sepsis preventive therapeutic agent |
Also Published As
| Publication number | Publication date |
|---|---|
| US9828357B2 (en) | 2017-11-28 |
| CA2985325C (en) | 2023-09-26 |
| UY36675A (es) | 2016-12-30 |
| EA201792469A1 (ru) | 2018-06-29 |
| ES2772703T3 (es) | 2020-07-08 |
| CN107835800A (zh) | 2018-03-23 |
| WO2016182036A1 (en) | 2016-11-17 |
| US20160326133A1 (en) | 2016-11-10 |
| US20170066737A1 (en) | 2017-03-09 |
| US9533966B2 (en) | 2017-01-03 |
| CA2985325A1 (en) | 2016-11-17 |
| EP3294706A1 (en) | 2018-03-21 |
| JP6718884B2 (ja) | 2020-07-08 |
| AR104539A1 (es) | 2017-07-26 |
| CN107835800B (zh) | 2019-11-26 |
| JP2018516875A (ja) | 2018-06-28 |
| US20160326102A1 (en) | 2016-11-10 |
| EP3294706B1 (en) | 2019-12-04 |
| BR112017023818A2 (pt) | 2018-07-31 |
| TW201704206A (zh) | 2017-02-01 |
| US9611244B2 (en) | 2017-04-04 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| MM4A | Lapse of a eurasian patent due to non-payment of renewal fees within the time limit in the following designated state(s) |
Designated state(s): AM AZ BY KZ KG TJ TM |