EA032480B1 - Способы повышения устойчивости скелетных мышц к утомлению - Google Patents
Способы повышения устойчивости скелетных мышц к утомлению Download PDFInfo
- Publication number
- EA032480B1 EA032480B1 EA201491666A EA201491666A EA032480B1 EA 032480 B1 EA032480 B1 EA 032480B1 EA 201491666 A EA201491666 A EA 201491666A EA 201491666 A EA201491666 A EA 201491666A EA 032480 B1 EA032480 B1 EA 032480B1
- Authority
- EA
- Eurasian Patent Office
- Prior art keywords
- compound
- skeletal muscle
- imidazo
- pyrazin
- muscle
- Prior art date
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Classifications
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- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/4985—Pyrazines or piperazines ortho- or peri-condensed with heterocyclic ring systems
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- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
- A61K31/437—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a five-membered ring having nitrogen as a ring hetero atom, e.g. indolizine, beta-carboline
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- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
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Landscapes
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
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- Urology & Nephrology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (5)
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| US201261646842P | 2012-05-14 | 2012-05-14 | |
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| US201261735809P | 2012-12-11 | 2012-12-11 | |
| PCT/US2013/036114 WO2013155262A2 (en) | 2012-04-11 | 2013-04-11 | Methods for improving resistance to skeletal muscle fatigue |
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| EA201491666A1 EA201491666A1 (ru) | 2015-03-31 |
| EA032480B1 true EA032480B1 (ru) | 2019-06-28 |
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| EA201491666A EA032480B1 (ru) | 2012-04-11 | 2013-04-11 | Способы повышения устойчивости скелетных мышц к утомлению |
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| EP (1) | EP2836590A4 (enExample) |
| JP (2) | JP6352244B2 (enExample) |
| KR (1) | KR102163931B1 (enExample) |
| CN (2) | CN111840294A (enExample) |
| AU (3) | AU2013245917A1 (enExample) |
| BR (1) | BR112014025251B1 (enExample) |
| CA (1) | CA2869675C (enExample) |
| EA (1) | EA032480B1 (enExample) |
| HK (1) | HK1206389A1 (enExample) |
| IL (2) | IL234886A (enExample) |
| MX (1) | MX2014012179A (enExample) |
| PH (1) | PH12014502286A1 (enExample) |
| SG (2) | SG10201704166RA (enExample) |
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Families Citing this family (15)
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| US8299248B2 (en) | 2006-08-02 | 2012-10-30 | Cytokinetics, Incorporated | Certain 1H-imidazo[4,5-b]pyrazin-2(3H)-ones and 1H-imidazo[4,5-b]pyrazin-2-ols and methods for their use |
| AR081331A1 (es) | 2010-04-23 | 2012-08-08 | Cytokinetics Inc | Amino- pirimidinas composiciones de las mismas y metodos para el uso de los mismos |
| AR081626A1 (es) | 2010-04-23 | 2012-10-10 | Cytokinetics Inc | Compuestos amino-piridazinicos, composiciones farmaceuticas que los contienen y uso de los mismos para tratar trastornos musculares cardiacos y esqueleticos |
| US9133123B2 (en) | 2010-04-23 | 2015-09-15 | Cytokinetics, Inc. | Certain amino-pyridines and amino-triazines, compositions thereof, and methods for their use |
| KR101951220B1 (ko) | 2011-07-13 | 2019-02-22 | 싸이토키네틱스, 인코포레이티드 | 조합 als 치료법 |
| KR20150131224A (ko) | 2013-03-14 | 2015-11-24 | 노파르티스 아게 | 돌연변이 idh의 억제제로서의 3-피리미딘-4-일-옥사졸리딘-2-온 |
| RS63018B1 (sr) * | 2014-04-29 | 2022-04-29 | Cytokinetics Inc | Metode za smanjenje opadanja vitalnog kapaciteta |
| MX389591B (es) | 2014-08-29 | 2025-03-20 | Tes Pharma S R L | INHIBIDORES DE ACIDO A-AMINO-ß-CARBOXIMUCONICO SEMIALDEHIDO DESCARBOXILASA |
| MX2017002853A (es) | 2014-09-09 | 2018-01-12 | Astellas Pharma Inc | Nueva composicion farmaceutica para la prevencion y/o el tratamiento de la incontinencia urinaria. |
| SG11201806416XA (en) | 2016-02-12 | 2018-08-30 | Astellas Pharma Inc | Tetrahydroisoquinoline derivatives |
| CN109476645A (zh) | 2016-07-14 | 2019-03-15 | 辉瑞大药厂 | 作为vanin-1酶抑制剂的新的嘧啶甲酰胺 |
| WO2018165520A1 (en) | 2017-03-10 | 2018-09-13 | Vps-3, Inc. | Metalloenzyme inhibitor compounds |
| BR112022000281A2 (pt) | 2019-07-23 | 2022-02-22 | Amorphical Ltd | Carbonato de cálcio amorfo para aprimorar o desempenho atlético |
| AR124008A1 (es) | 2020-11-06 | 2023-02-01 | Cytokinetics Inc | 1,4-diazepanonas bicíclicas y sus usos terapéuticos |
| WO2023107705A1 (en) | 2021-12-10 | 2023-06-15 | Incyte Corporation | Bicyclic amines as cdk12 inhibitors |
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| US20090029345A1 (en) * | 2006-08-01 | 2009-01-29 | Alan Russell | Modulating skeletal muscle |
| WO2011133888A1 (en) * | 2010-04-23 | 2011-10-27 | Cytokinetics, Inc. | Certain amino-pyrimidines, compositions thereof, and methods for their use |
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| JP2005139081A (ja) * | 2003-11-04 | 2005-06-02 | Takada Seiyaku Kk | ビントペロール含有製剤 |
| SI2583970T1 (sl) * | 2006-08-02 | 2016-03-31 | Cytokinetics, Inc. | Določene kemijske enote, sestavki in postopki, ki obsegajo imidazopirimidine |
| US8299248B2 (en) * | 2006-08-02 | 2012-10-30 | Cytokinetics, Incorporated | Certain 1H-imidazo[4,5-b]pyrazin-2(3H)-ones and 1H-imidazo[4,5-b]pyrazin-2-ols and methods for their use |
| EA201001224A1 (ru) * | 2008-02-04 | 2011-08-30 | Цитокинетикс, Инкорпорейтед | Химические соединения, композиции и способы их использования |
| MX354965B (es) * | 2012-04-02 | 2018-03-27 | Cytokinetics Inc | Metodo para mejorar la funcion del diafragma. |
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2014
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2019
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| US20090029345A1 (en) * | 2006-08-01 | 2009-01-29 | Alan Russell | Modulating skeletal muscle |
| WO2011133888A1 (en) * | 2010-04-23 | 2011-10-27 | Cytokinetics, Inc. | Certain amino-pyrimidines, compositions thereof, and methods for their use |
Non-Patent Citations (1)
| Title |
|---|
| HIATT, W.R. et al. "Efficacy and Tolerability of the Novel Fast Skeletal Muscle Troponin Activator, CK-2017357, in Patients with Claudication", 22nd Annual Sessions of the Society for Vascular Medicine, Boston, MA, June 2011 [poster presentation]; [Retrieved on 2013-08-20]. Retrieved from the Internet at URL:www.cytokinetics.com/pdf/4022-20110531-rev004.pdf; introduction, paragraphs 1-2, figure 1; methods, lines 1-7, 18-28; clinical results, figures 4A-C, paragraph 1 * |
Also Published As
| Publication number | Publication date |
|---|---|
| EA201491666A1 (ru) | 2015-03-31 |
| CN104395458A (zh) | 2015-03-04 |
| JP6352244B2 (ja) | 2018-07-04 |
| CN111840294A (zh) | 2020-10-30 |
| US20150250784A1 (en) | 2015-09-10 |
| KR20160046694A (ko) | 2016-04-29 |
| MX2014012179A (es) | 2015-07-14 |
| SG10201704166RA (en) | 2017-06-29 |
| EP2836590A4 (en) | 2016-04-13 |
| JP2015516392A (ja) | 2015-06-11 |
| WO2013155262A2 (en) | 2013-10-17 |
| BR112014025251B1 (pt) | 2021-03-02 |
| CA2869675C (en) | 2022-06-14 |
| PH12014502286B1 (en) | 2014-12-15 |
| HK1206389A1 (en) | 2016-01-08 |
| WO2013155262A3 (en) | 2013-12-27 |
| IL250473A0 (en) | 2017-03-30 |
| AU2018200930A1 (en) | 2018-03-01 |
| CA2869675A1 (en) | 2013-10-17 |
| KR102163931B1 (ko) | 2020-10-12 |
| JP6535727B2 (ja) | 2019-06-26 |
| JP2018048209A (ja) | 2018-03-29 |
| EP2836590A2 (en) | 2015-02-18 |
| PH12014502286A1 (en) | 2014-12-15 |
| SG11201406359TA (en) | 2014-11-27 |
| AU2019268177A1 (en) | 2019-12-12 |
| US20190167676A1 (en) | 2019-06-06 |
| AU2013245917A1 (en) | 2014-10-23 |
| IL234886A (en) | 2017-02-28 |
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