EA024142B1 - Туалетное мыло с улучшенной пенообразующей способностью - Google Patents
Туалетное мыло с улучшенной пенообразующей способностью Download PDFInfo
- Publication number
- EA024142B1 EA024142B1 EA201491022A EA201491022A EA024142B1 EA 024142 B1 EA024142 B1 EA 024142B1 EA 201491022 A EA201491022 A EA 201491022A EA 201491022 A EA201491022 A EA 201491022A EA 024142 B1 EA024142 B1 EA 024142B1
- Authority
- EA
- Eurasian Patent Office
- Prior art keywords
- mixture
- weight
- fatty acid
- soaps
- acids
- Prior art date
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- 239000000344 soap Substances 0.000 title claims abstract description 125
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- TWJNQYPJQDRXPH-UHFFFAOYSA-N 2-cyanobenzohydrazide Chemical compound NNC(=O)C1=CC=CC=C1C#N TWJNQYPJQDRXPH-UHFFFAOYSA-N 0.000 claims abstract description 13
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- POULHZVOKOAJMA-UHFFFAOYSA-N dodecanoic acid Chemical compound CCCCCCCCCCCC(O)=O POULHZVOKOAJMA-UHFFFAOYSA-N 0.000 claims description 29
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Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
- A61K8/36—Carboxylic acids; Salts or anhydrides thereof
- A61K8/361—Carboxylic acids having more than seven carbon atoms in an unbroken chain; Salts or anhydrides thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/10—Washing or bathing preparations
-
- C—CHEMISTRY; METALLURGY
- C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
- C11D—DETERGENT COMPOSITIONS; USE OF SINGLE SUBSTANCES AS DETERGENTS; SOAP OR SOAP-MAKING; RESIN SOAPS; RECOVERY OF GLYCEROL
- C11D9/00—Compositions of detergents based essentially on soap
- C11D9/007—Soaps or soap mixtures with well defined chain length
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Birds (AREA)
- Emergency Medicine (AREA)
- Epidemiology (AREA)
- Dermatology (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Wood Science & Technology (AREA)
- Organic Chemistry (AREA)
- Detergent Compositions (AREA)
- Cosmetics (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201161563194P | 2011-11-23 | 2011-11-23 | |
| PCT/EP2012/073008 WO2013076047A1 (en) | 2011-11-23 | 2012-11-19 | Toilet soap with improved lather |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| EA201491022A1 EA201491022A1 (ru) | 2014-09-30 |
| EA024142B1 true EA024142B1 (ru) | 2016-08-31 |
Family
ID=47226145
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| EA201491022A EA024142B1 (ru) | 2011-11-23 | 2012-11-19 | Туалетное мыло с улучшенной пенообразующей способностью |
Country Status (10)
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|---|---|
| US (2) | US8492323B2 (enExample) |
| EP (1) | EP2782989B1 (enExample) |
| CN (1) | CN103946362B (enExample) |
| BR (1) | BR112014011724B1 (enExample) |
| EA (1) | EA024142B1 (enExample) |
| ES (1) | ES2568069T3 (enExample) |
| IN (1) | IN2014MN00859A (enExample) |
| MX (1) | MX338158B (enExample) |
| WO (1) | WO2013076047A1 (enExample) |
| ZA (1) | ZA201403382B (enExample) |
Families Citing this family (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2015038601A1 (en) * | 2013-09-11 | 2015-03-19 | Lubrizol Advanced Materials, Inc. | Soap compositions and treatment methods for the mitigation of winter season pruritus |
| BR112016011379B1 (pt) | 2013-11-25 | 2022-01-04 | Unilever Ip Holdings B.V. | Barra para a higiene pessoal |
| MX388224B (es) * | 2014-07-22 | 2025-03-19 | Unilever Ip Holdings B V | Composicion de barra y metodos para mantener espuma mejorada en presencia de agua con alta concentracion de electrolitos. |
| US9844524B2 (en) * | 2015-06-29 | 2017-12-19 | Vanguard Soap LLC | Soap compositions and methods |
| MX381026B (es) | 2015-07-29 | 2025-03-12 | Unilever Ip Holdings B V | Composición de limpieza con mejor disponibilidad del agente de beneficio. |
| BR112018005126B1 (pt) * | 2015-10-16 | 2022-06-07 | Unilever Ip Holdings B.V. | Composição de barra de sabão |
| EP3931295B1 (en) | 2019-03-01 | 2022-12-07 | Unilever IP Holdings B.V. | A soap bar with improved perfume impact and deposition of actives |
| JP7439118B2 (ja) * | 2019-03-01 | 2024-02-27 | ユニリーバー・アイピー・ホールディングス・ベスローテン・ヴェンノーツハップ | カプレートに対する不飽和ｃ１８石鹸の比を最小限に抑えながらｃ１０石鹸を含むバー組成物 |
| MX2022010131A (es) * | 2020-02-20 | 2022-09-02 | Unilever Ip Holdings B V | Una composicion de jabon. |
| WO2024036124A1 (en) * | 2022-08-12 | 2024-02-15 | The Procter & Gamble Company | Solid dissolvable compositions |
| WO2024036123A1 (en) * | 2022-08-12 | 2024-02-15 | The Procter & Gamble Company | Low-water compositions |
| US20240052259A1 (en) * | 2022-08-12 | 2024-02-15 | The Procter & Gamble Company | Solid dissolvable compositions |
| MX2024006096A (es) * | 2022-08-12 | 2024-05-30 | Procter & Gamble | Composiciones solidas disolubles. |
| US20240060013A1 (en) * | 2022-08-12 | 2024-02-22 | The Procter & Gamble Company | Solid dissolvable compositions |
Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3043778A (en) * | 1958-02-20 | 1962-07-10 | Lever Brothers Ltd | Soap bar compositions |
| GB1287625A (en) * | 1969-08-25 | 1972-09-06 | Procter & Gamble Ltd | Improved toilet soap |
| US5264144A (en) * | 1991-05-30 | 1993-11-23 | The Procter & Gamble Company | Freezer personal cleansing bar with selected fatty acid soaps for improved mildness and good lather |
| US5540852A (en) * | 1995-01-31 | 1996-07-30 | The Procter & Gamble Company | Personal cleansing bar with tailored fatty acid soap |
| US20090286706A1 (en) * | 2005-12-07 | 2009-11-19 | Debojit Chakrabarty | Detergent Composition |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2798053A (en) | 1952-09-03 | 1957-07-02 | Goodrich Co B F | Carboxylic polymers |
| US3723325A (en) | 1967-09-27 | 1973-03-27 | Procter & Gamble | Detergent compositions containing particle deposition enhancing agents |
| GB2160216B (en) * | 1984-07-19 | 1986-10-22 | Simmons Nominees Pty Ltd | Insect-repellent and insecticidal soap compsition |
| AU2446192A (en) | 1991-08-13 | 1993-03-16 | Procter & Gamble Company, The | Mild soap-synbar |
| GB9309442D0 (en) | 1993-05-07 | 1993-06-23 | Unilever Plc | Toilet soap bars |
| CN105175257A (zh) * | 2006-02-10 | 2015-12-23 | 杜邦塔特和莱尔生物产品有限责任公司 | 包括生物学基1,3-丙二醇的单酯和二酯的组合物 |
-
2012
- 2012-09-24 US US13/625,273 patent/US8492323B2/en active Active
- 2012-11-19 EP EP12791150.1A patent/EP2782989B1/en active Active
- 2012-11-19 EA EA201491022A patent/EA024142B1/ru not_active IP Right Cessation
- 2012-11-19 WO PCT/EP2012/073008 patent/WO2013076047A1/en not_active Ceased
- 2012-11-19 MX MX2014006267A patent/MX338158B/es active IP Right Grant
- 2012-11-19 IN IN859MUN2014 patent/IN2014MN00859A/en unknown
- 2012-11-19 BR BR112014011724-1A patent/BR112014011724B1/pt active IP Right Grant
- 2012-11-19 ES ES12791150.1T patent/ES2568069T3/es active Active
- 2012-11-19 CN CN201280057752.0A patent/CN103946362B/zh active Active
-
2013
- 2013-06-20 US US13/922,764 patent/US8722603B2/en active Active
-
2014
- 2014-05-12 ZA ZA2014/03382A patent/ZA201403382B/en unknown
Patent Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3043778A (en) * | 1958-02-20 | 1962-07-10 | Lever Brothers Ltd | Soap bar compositions |
| GB1287625A (en) * | 1969-08-25 | 1972-09-06 | Procter & Gamble Ltd | Improved toilet soap |
| US5264144A (en) * | 1991-05-30 | 1993-11-23 | The Procter & Gamble Company | Freezer personal cleansing bar with selected fatty acid soaps for improved mildness and good lather |
| US5540852A (en) * | 1995-01-31 | 1996-07-30 | The Procter & Gamble Company | Personal cleansing bar with tailored fatty acid soap |
| US20090286706A1 (en) * | 2005-12-07 | 2009-11-19 | Debojit Chakrabarty | Detergent Composition |
Also Published As
| Publication number | Publication date |
|---|---|
| IN2014MN00859A (enExample) | 2015-04-17 |
| BR112014011724B1 (pt) | 2021-04-20 |
| US8722603B2 (en) | 2014-05-13 |
| CN103946362A (zh) | 2014-07-23 |
| BR112014011724A2 (pt) | 2017-05-30 |
| US8492323B2 (en) | 2013-07-23 |
| EA201491022A1 (ru) | 2014-09-30 |
| MX338158B (es) | 2016-04-05 |
| EP2782989A1 (en) | 2014-10-01 |
| CN103946362B (zh) | 2016-11-23 |
| MX2014006267A (es) | 2014-07-09 |
| US20130281343A1 (en) | 2013-10-24 |
| WO2013076047A1 (en) | 2013-05-30 |
| EP2782989B1 (en) | 2016-03-16 |
| ES2568069T3 (es) | 2016-04-27 |
| US20130130960A1 (en) | 2013-05-23 |
| ZA201403382B (en) | 2016-01-27 |
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| Date | Code | Title | Description |
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| MM4A | Lapse of a eurasian patent due to non-payment of renewal fees within the time limit in the following designated state(s) |
Designated state(s): AM AZ BY KZ KG TJ TM |