EA019240B1 - Арилвинилазациклоалкановые соединения и способы их получения и применения - Google Patents
Арилвинилазациклоалкановые соединения и способы их получения и применения Download PDFInfo
- Publication number
- EA019240B1 EA019240B1 EA200900706A EA200900706A EA019240B1 EA 019240 B1 EA019240 B1 EA 019240B1 EA 200900706 A EA200900706 A EA 200900706A EA 200900706 A EA200900706 A EA 200900706A EA 019240 B1 EA019240 B1 EA 019240B1
- Authority
- EA
- Eurasian Patent Office
- Prior art keywords
- hydrogen
- alkyl
- aryl
- phenyl
- heteroaryl
- Prior art date
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| EA200501425A EA010870B1 (ru) | 2003-03-05 | 2004-03-04 | Арилвинилазациклоалкановые соединения и способы их получения и применения |
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| US10421745B2 (en) | 2008-12-01 | 2019-09-24 | Oyster Point Pharma, Inc. | Salt forms of (R)-5-((E)-2-pyrrolidin-3-ylvinyl)pyrimidine |
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| US7098331B2 (en) * | 2003-03-05 | 2006-08-29 | Targacept, Inc. | Arylvinylazacycloalkane compounds and methods of preparation and use thereof |
| FR2896800B1 (fr) * | 2006-01-30 | 2008-04-11 | Servier Lab | Nouveaux composes pyridinylaminoalkylene-et pyridinyloxyalkylene-cyclopropanamines polysubstitues, leur procede de preparation et les compositions pharmaceutiques qui les contiennent. |
| WO2008157365A2 (en) * | 2007-06-15 | 2008-12-24 | Targacept, Inc. | Vinylazacycloalkanes for treating neuropathic pain |
| US20110098312A1 (en) * | 2008-05-12 | 2011-04-28 | Targacept ,Inc | Methods for preventing the development of retinopathy by the oral administration of nnr ligands |
| TW201024283A (en) * | 2008-12-01 | 2010-07-01 | Targacept Inc | Synthesis and novel salt forms of (R)-3-((E)-2-(pyrrolidin-3-yl)vinyl)-5-(tetrahydropyran-4-yloxy)pyridine |
| WO2010065443A1 (en) * | 2008-12-01 | 2010-06-10 | Targacept, Inc. | Synthesis and novel salt forms of (r)-5-((e)-2-(pyrrolidin-3-ylvinyl)pyrimidine |
| WO2010080757A2 (en) | 2009-01-07 | 2010-07-15 | Astrazeneca Ab | Combinations with an alpha-4beta-2 nicotinic agonist |
| BRPI1014247A2 (pt) * | 2009-06-17 | 2016-04-12 | Targacept Inc | reversão da discinesia induzida pela l-dopa por ligantes de receptores nocotínicos neuronais. |
| US8802694B2 (en) | 2009-12-07 | 2014-08-12 | Targacept, Inc. | 3,6-diazabicyclo[3.1.1]heptanes as neuronal nicotinic acetycholine receptor ligands |
| US20130237550A1 (en) * | 2010-03-11 | 2013-09-12 | Targacept, Inc. | Arylvinylazacycloalkane compounds for constipation |
| US20110274628A1 (en) * | 2010-05-07 | 2011-11-10 | Borschke August J | Nicotine-containing pharmaceutical compositions |
| US20140081714A1 (en) * | 2012-09-19 | 2014-03-20 | Salesforce.Com, Inc. | Systems and methods of rewarding users in an on-demand system |
| US20140278929A1 (en) * | 2013-03-15 | 2014-09-18 | Yahoo! Inc. | System and method identifying opportunities for advertising entities based on user goal achievement |
| MX385698B (es) * | 2016-04-07 | 2025-03-18 | Oyster Point Pharma Inc | Uso de un compuesto que comprende un grupo pirrolidinilo y pirimidinilo para tratar enfermedades oculares |
| KR101848601B1 (ko) * | 2016-07-27 | 2018-04-12 | 송기봉 | 일회용 위생 티슈 |
| WO2020014217A1 (en) | 2018-07-10 | 2020-01-16 | Oyster Point Pharma, Inc. | Methods of treating ocular conditions |
| EP3820443A1 (en) | 2018-07-10 | 2021-05-19 | Oyster Point Pharma, Inc. | Combinations of positive allosteric modulators and nicotinic acetylcholine receptor agonists for treating ocular conditions |
| ES3039903T3 (en) | 2020-04-28 | 2025-10-27 | Oyster Point Pharma Inc | Local administration of nicotinic acetylcholine receptor agonists for the inhibition of coronavirus infections |
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US10421745B2 (en) | 2008-12-01 | 2019-09-24 | Oyster Point Pharma, Inc. | Salt forms of (R)-5-((E)-2-pyrrolidin-3-ylvinyl)pyrimidine |
| US10919879B2 (en) | 2008-12-01 | 2021-02-16 | Oyster Point Pharma, Inc. | Synthesis and novel salt forms of (R)-5-((E)-2-pyrrolidin-3-ylvinyl)pyrimidine |
| US11542253B2 (en) | 2008-12-01 | 2023-01-03 | Oyster Point Pharma, Inc. | Synthesis and novel salt forms of (R)-5-((E)-2-pyrrolidin-3-ylvinyl)pyrimidine |
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