EA018064B1 - Способ лечения депрессии - Google Patents
Способ лечения депрессии Download PDFInfo
- Publication number
- EA018064B1 EA018064B1 EA201000280A EA201000280A EA018064B1 EA 018064 B1 EA018064 B1 EA 018064B1 EA 201000280 A EA201000280 A EA 201000280A EA 201000280 A EA201000280 A EA 201000280A EA 018064 B1 EA018064 B1 EA 018064B1
- Authority
- EA
- Eurasian Patent Office
- Prior art keywords
- escitalopram oxalate
- animals
- cariprazine
- treatment
- cariprazine hydrochloride
- Prior art date
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- A61K31/343—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide condensed with a carbocyclic ring, e.g. coumaran, bufuralol, befunolol, clobenfurol, amiodarone
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Landscapes
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- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
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| PCT/US2008/072066 WO2009020897A1 (en) | 2007-08-03 | 2008-08-04 | Pharmaceutical compositions containing dopamine receptor ligands and methods of treatment using dopamine recptor ligands |
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| DK2317852T3 (en) | 2008-07-16 | 2015-03-23 | Richter Gedeon Nyrt | PHARMACEUTICAL FORMULATIONS CONTAINING dopamine receptor ligands |
| US20110117214A1 (en) * | 2009-11-16 | 2011-05-19 | Auspex Pharmaceuticals, Inc. | Cyclohexyl urea modulators of d2 receptors and/or d3 receptors |
| CN103052636B (zh) | 2010-06-18 | 2016-03-09 | 阿尔托斯治疗有限责任公司 | D2拮抗剂及其合成方法和使用方法 |
| WO2014031162A1 (en) | 2012-08-20 | 2014-02-27 | Forest Laboratories Holdings Limited | Crystalline form of carbamoyl-cyclohexane derivatives |
| US11274087B2 (en) | 2016-07-08 | 2022-03-15 | Richter Gedeon Nyrt. | Industrial process for the preparation of cariprazine |
| HUP1700253A1 (hu) * | 2017-06-13 | 2019-01-28 | Richter Gedeon Nyrt | Szilárd orális gyógyszerkészítmények |
| US12459965B2 (en) | 2017-10-09 | 2025-11-04 | Compass Pathfinder Limited | Preparation of psilocybin, different polymorphic forms, intermediates, formulations and their use |
| GB2571696B (en) | 2017-10-09 | 2020-05-27 | Compass Pathways Ltd | Large scale method for the preparation of Psilocybin and formulations of Psilocybin so produced |
| US11547707B2 (en) | 2019-04-10 | 2023-01-10 | Richter Gedeon Nyrt. | Carbamoyl cyclohexane derivatives for treating autism spectrum disorder |
| HU231500B1 (hu) * | 2019-04-10 | 2024-04-28 | Richter Gedeon Nyrt | Karbamoil-ciklohexán származékok autizmus spektrum betegség kezelésére |
| JP2022529353A (ja) | 2019-04-17 | 2022-06-21 | コンパス パスファインダー リミテッド | 神経認知障害、慢性疼痛を治療し、炎症を低減させる方法 |
| GEAP202416526A (en) * | 2021-10-28 | 2024-09-25 | Richter Gedeon Nyrt | Treatment of major depressive disorder |
| AU2022409230A1 (en) * | 2021-12-13 | 2024-06-20 | Compass Pathfinder Limited | Psilocybin and an adjunctive serotonin reuptake inhibitor for use in the treatment of treatment-resistant depression |
| EP4493274A1 (en) | 2022-03-17 | 2025-01-22 | Mapi Pharma Ltd. | Depot systems comprising cariprazine or salts thereof |
Citations (3)
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| US7030122B2 (en) * | 2002-04-12 | 2006-04-18 | Sepracor Inc. | 1,4-disubstituted piperazine ligands for neurotransmitter receptors |
| US20060229297A1 (en) * | 2003-08-04 | 2006-10-12 | Richter Gedeon Vegyeszeti Gyar Rt. | (THIO) Carbamoyl-cyclohexane derivatives as D3/D2 receptor antagonists |
| US20070042014A1 (en) * | 2003-09-04 | 2007-02-22 | H. Lundbeck A/S | Combination of a serotonin reuptake inhibitor and loxapine |
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| ZA977967B (en) * | 1996-09-23 | 1999-03-04 | Lilly Co Eli | Combination therapy for treatment of psychoses |
| US6960577B2 (en) * | 1998-05-22 | 2005-11-01 | Eli Lilly And Company | Combination therapy for treatment of refractory depression |
| US6556540B1 (en) * | 1998-05-29 | 2003-04-29 | Paradyne Corporation | System and method for non-intrusive measurement of service quality in a communications network |
| EP1298124B1 (en) * | 1999-10-25 | 2007-02-28 | H. Lundbeck A/S | Method For the Preparation of Citalopram |
| UA77650C2 (en) * | 1999-12-06 | 2007-01-15 | Lundbeck & Co As H | Use of serotonin reuptake inhibitor in combination with deramcyclane |
| CN1509169A (zh) * | 2001-05-01 | 2004-06-30 | H��¡�±�������˾ | 对映体纯艾司西酞普兰的用途 |
| IL165840A0 (en) * | 2002-06-20 | 2006-01-15 | Lundbeck & Co As H | Combination therapy wherein a serotonin reuptake inhibitor is used |
| HUP0500170A3 (en) * | 2005-02-03 | 2007-11-28 | Richter Gedeon Nyrt | Piperazine derivatives, process for producing them and pharmaceutical compositions containing them |
| TW200812993A (en) * | 2006-05-02 | 2008-03-16 | Lundbeck & Co As H | New uses of escitalopram |
| HU230748B1 (hu) * | 2007-05-11 | 2018-02-28 | Richter Gedeon Nyrt | Új piperazin só és előállítási eljárása |
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| US7030122B2 (en) * | 2002-04-12 | 2006-04-18 | Sepracor Inc. | 1,4-disubstituted piperazine ligands for neurotransmitter receptors |
| US20060229297A1 (en) * | 2003-08-04 | 2006-10-12 | Richter Gedeon Vegyeszeti Gyar Rt. | (THIO) Carbamoyl-cyclohexane derivatives as D3/D2 receptor antagonists |
| US20070042014A1 (en) * | 2003-09-04 | 2007-02-22 | H. Lundbeck A/S | Combination of a serotonin reuptake inhibitor and loxapine |
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| Numberg. Managing Treatment-Emergent Sexual Dysfunction Associated with Serotogenic Antidepressants: Before and After Sildenafil. Journal of Psychiatric Practice. 2001, vol. 7, pg 98, col 1 para 2 and col 2 para 4 * |
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| AU2008283989A1 (en) | 2009-02-12 |
| MY157192A (en) | 2016-05-13 |
| CN101815519A (zh) | 2010-08-25 |
| NO2185155T3 (OSRAM) | 2018-03-03 |
| CY1119828T1 (el) | 2018-06-27 |
| WO2009020897A1 (en) | 2009-02-12 |
| PL2185155T3 (pl) | 2018-03-30 |
| EP2185155A4 (en) | 2012-04-25 |
| JP5460594B2 (ja) | 2014-04-02 |
| HK1144784A1 (en) | 2011-03-11 |
| CN101815519B (zh) | 2013-08-21 |
| HUE036004T2 (hu) | 2018-06-28 |
| US20120028991A1 (en) | 2012-02-02 |
| PT2185155T (pt) | 2018-01-04 |
| HRP20171908T1 (hr) | 2018-01-26 |
| EA201000280A1 (ru) | 2010-08-30 |
| KR101612563B1 (ko) | 2016-04-14 |
| CA2695519A1 (en) | 2009-02-12 |
| JP2010535790A (ja) | 2010-11-25 |
| LT2185155T (lt) | 2017-12-11 |
| EP2185155B1 (en) | 2017-10-04 |
| KR20100059830A (ko) | 2010-06-04 |
| DK2185155T3 (en) | 2018-01-02 |
| SI2185155T1 (en) | 2018-02-28 |
| AU2008283989B2 (en) | 2013-12-05 |
| EP2185155A1 (en) | 2010-05-19 |
| US20110015208A1 (en) | 2011-01-20 |
| ES2653852T3 (es) | 2018-02-09 |
| US20090036468A1 (en) | 2009-02-05 |
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