EA009289B1 - ЛЕЧЕНИЕ ХРОНИЧЕСКОЙ ВОСПАЛИТЕЛЬНОЙ ДЕМИЕЛИНИЗИРУЮЩЕЙ ПОЛИНЕВРОПАТИИ С ИСПОЛЬЗОВАНИЕМ β-ИНТЕРФЕРОНА - Google Patents

ЛЕЧЕНИЕ ХРОНИЧЕСКОЙ ВОСПАЛИТЕЛЬНОЙ ДЕМИЕЛИНИЗИРУЮЩЕЙ ПОЛИНЕВРОПАТИИ С ИСПОЛЬЗОВАНИЕМ β-ИНТЕРФЕРОНА Download PDF

Info

Publication number
EA009289B1
EA009289B1 EA200500545A EA200500545A EA009289B1 EA 009289 B1 EA009289 B1 EA 009289B1 EA 200500545 A EA200500545 A EA 200500545A EA 200500545 A EA200500545 A EA 200500545A EA 009289 B1 EA009289 B1 EA 009289B1
Authority
EA
Eurasian Patent Office
Prior art keywords
ιεν
use according
ιρν
treatment
administered
Prior art date
Application number
EA200500545A
Other languages
English (en)
Russian (ru)
Other versions
EA200500545A3 (ru
EA200500545A2 (ru
Inventor
Альфред Сэндрок
Original Assignee
Байоджен Айдек Ма Инк.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Байоджен Айдек Ма Инк. filed Critical Байоджен Айдек Ма Инк.
Publication of EA200500545A2 publication Critical patent/EA200500545A2/ru
Publication of EA200500545A3 publication Critical patent/EA200500545A3/ru
Publication of EA009289B1 publication Critical patent/EA009289B1/ru

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/19Cytokines; Lymphokines; Interferons
    • A61K38/21Interferons [IFN]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/19Cytokines; Lymphokines; Interferons
    • A61K38/21Interferons [IFN]
    • A61K38/215IFN-beta
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/04Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/12Cyclic peptides, e.g. bacitracins; Polymyxins; Gramicidins S, C; Tyrocidins A, B or C
    • A61K38/13Cyclosporins
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00Drugs for disorders of the muscular or neuromuscular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/02Drugs for disorders of the nervous system for peripheral neuropathies
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/14Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • A61P37/06Immunosuppressants, e.g. drugs for graft rejection
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • A61P7/08Plasma substitutes; Perfusion solutions; Dialytics or haemodialytics; Drugs for electrolytic or acid-base disorders, e.g. hypovolemic shock
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2319/00Fusion polypeptide
    • C07K2319/30Non-immunoglobulin-derived peptide or protein having an immunoglobulin constant or Fc region, or a fragment thereof, attached thereto

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Immunology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Epidemiology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Neurology (AREA)
  • Zoology (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Transplantation (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Rheumatology (AREA)
  • Pain & Pain Management (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Psychology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Medicinal Preparation (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
EA200500545A 2002-09-27 2003-09-26 ЛЕЧЕНИЕ ХРОНИЧЕСКОЙ ВОСПАЛИТЕЛЬНОЙ ДЕМИЕЛИНИЗИРУЮЩЕЙ ПОЛИНЕВРОПАТИИ С ИСПОЛЬЗОВАНИЕМ β-ИНТЕРФЕРОНА EA009289B1 (ru)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US41430702P 2002-09-27 2002-09-27
PCT/US2003/030532 WO2004028472A2 (en) 2002-09-27 2003-09-26 THERAPIES FOR CHRONIC INFLAMMATORY DEMYELINATING POLYNEUROPATHY USING INTERFERON-β

Publications (3)

Publication Number Publication Date
EA200500545A2 EA200500545A2 (ru) 2005-08-25
EA200500545A3 EA200500545A3 (ru) 2007-04-27
EA009289B1 true EA009289B1 (ru) 2007-12-28

Family

ID=32043377

Family Applications (1)

Application Number Title Priority Date Filing Date
EA200500545A EA009289B1 (ru) 2002-09-27 2003-09-26 ЛЕЧЕНИЕ ХРОНИЧЕСКОЙ ВОСПАЛИТЕЛЬНОЙ ДЕМИЕЛИНИЗИРУЮЩЕЙ ПОЛИНЕВРОПАТИИ С ИСПОЛЬЗОВАНИЕМ β-ИНТЕРФЕРОНА

Country Status (21)

Country Link
US (2) US20060182715A1 (https=)
EP (1) EP1575531B9 (https=)
JP (3) JP2006513990A (https=)
KR (1) KR20050059195A (https=)
CN (2) CN102038938A (https=)
AT (1) ATE520412T1 (https=)
AU (1) AU2003277006C1 (https=)
BR (1) BR0314548A (https=)
CA (1) CA2500189A1 (https=)
DK (1) DK1575531T3 (https=)
EA (1) EA009289B1 (https=)
GE (1) GEP20094699B (https=)
IS (1) IS7746A (https=)
MX (1) MXPA05003243A (https=)
NO (1) NO20052059L (https=)
NZ (1) NZ565990A (https=)
PL (1) PL377612A1 (https=)
RS (1) RS20050255A (https=)
UA (1) UA86749C2 (https=)
WO (1) WO2004028472A2 (https=)
ZA (1) ZA200502416B (https=)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2636456C2 (ru) * 2011-10-01 2017-11-23 Глитек, Инк. Гликозилированный полипептид и содержащая его фармацевтическая композиция

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
UA86749C2 (en) * 2002-09-27 2009-05-25 Байоджен Айдек Ма Инк. THERAPIES FOR CHRONIC INFLAMMATORY DEMYELINATING POLYNEUROPATHY USING INTERFERON-в
TW200633718A (en) * 2004-12-16 2006-10-01 Applied Research Systems Treatment of hepatitis c in the asian population
WO2008130382A2 (en) 2006-10-31 2008-10-30 East Carolina University Fusion proteins comprising an anti -inflammatory cytokine and an antigen for treatment of immune disorders
CA2757287C (en) 2009-03-31 2019-09-10 East Carolina University Cytokines and neuroantigens for treatment of immune disorders
GB201212878D0 (en) 2012-07-20 2012-09-05 Pike Justin Authentication method and system
EP3072513A1 (en) 2015-03-26 2016-09-28 Medday Biotin for treating Amyotrophic lateral sclerosis
GB201520760D0 (en) 2015-05-27 2016-01-06 Mypinpad Ltd And Licentia Group Ltd Encoding methods and systems
KR102454376B1 (ko) * 2018-07-04 2022-10-17 서울대학교산학협력단 신경손상의 면역세포치료
GB201916441D0 (en) 2019-11-12 2019-12-25 Mypinpad Ltd Computer-implemented system and method
KR20260005778A (ko) * 2024-07-02 2026-01-12 주식회사 카인사이언스 탈수초 질환 치료를 위한 펩타이드 및 IVIg의 병용 요법
KR20260005781A (ko) * 2024-07-02 2026-01-12 주식회사 카인사이언스 만성 염증성 탈수초 다발신경병증에 대한 펩타이드의 투여요법

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2166959C2 (ru) * 1994-04-12 2001-05-20 Рисерч Дивелопмент Фаундейшн Способ лечения аутоиммунных заболеваний с использованием интерферонов типа i
US6419934B1 (en) * 1999-02-24 2002-07-16 Edward L. Tobinick TNF modulators for treating neurological disorders associated with viral infection

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0154316B1 (en) * 1984-03-06 1989-09-13 Takeda Chemical Industries, Ltd. Chemically modified lymphokine and production thereof
ZA878295B (en) * 1986-11-06 1988-05-03 Amarillo Cell Culture Co. Inc. Treatment of immuno-resistant disease
DE3712564A1 (de) * 1987-04-14 1988-11-24 Bioferon Biochem Substanz Verfahren zur konstruktion einer animalen zellinie fuer die herstellung von humanem interferon-beta
DE4128319A1 (de) * 1991-08-27 1993-03-04 Bioferon Biochem Substanz Neues rekombinantes human-ifn-beta, verfahren zu dessen herstellung und dieses enthaltende pharmazeutische zubereitungen
US5545723A (en) * 1994-03-15 1996-08-13 Biogen Inc. Muteins of IFN-β
IL113280A (en) * 1994-04-12 2004-12-15 Res Dev Foundation A preparation for the treatment of self-immunization diseases with the help of interferon of one type
TW403653B (en) * 1995-12-25 2000-09-01 Otsuka Pharma Co Ltd Dry compositions
DK1121382T3 (da) * 1998-10-16 2006-11-13 Biogen Idec Inc Interferon-beta-fusionsproteiner og deres anvendelser
DK1656952T3 (da) * 1998-10-16 2014-01-20 Biogen Idec Inc Polyalkylenglycolkonjugater af interferon beta-1A og anvendelser deraf
EP2357192A1 (en) * 1999-02-26 2011-08-17 Human Genome Sciences, Inc. Human endokine alpha and methods of use
US6531122B1 (en) * 1999-08-27 2003-03-11 Maxygen Aps Interferon-β variants and conjugates
EP1334128A2 (en) * 2000-11-02 2003-08-13 Maxygen Aps New multimeric interferon beta polypeptides
EP2080771A3 (en) * 2001-02-27 2010-01-06 Maxygen Aps New interferon beta-like molecules
AU2002254174A1 (en) * 2001-03-13 2002-09-24 Vical Incorporated Interferon-beta polynucleotide therapy for autoimmune and inflammatory diseases
UA86749C2 (en) * 2002-09-27 2009-05-25 Байоджен Айдек Ма Инк. THERAPIES FOR CHRONIC INFLAMMATORY DEMYELINATING POLYNEUROPATHY USING INTERFERON-в

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2166959C2 (ru) * 1994-04-12 2001-05-20 Рисерч Дивелопмент Фаундейшн Способ лечения аутоиммунных заболеваний с использованием интерферонов типа i
US6419934B1 (en) * 1999-02-24 2002-07-16 Edward L. Tobinick TNF modulators for treating neurological disorders associated with viral infection

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
SAIDA K., Treatment of neuro-immunologic diseases by immunosuppres-sants, 1994, nov.52(11): 3046-52, referat, [Naydeno 12.12.2005], Medline [on-layn] PMID: 7996708 referat ÔÇ£Entsiklopediya lekarstv, registr lekarstvennykh sredstv RossiiÔÇØ, Moskva, 2001, str. 142, 364-365 *

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2636456C2 (ru) * 2011-10-01 2017-11-23 Глитек, Инк. Гликозилированный полипептид и содержащая его фармацевтическая композиция

Also Published As

Publication number Publication date
US20060182715A1 (en) 2006-08-17
MXPA05003243A (es) 2005-09-12
BR0314548A (pt) 2005-08-09
CN102038938A (zh) 2011-05-04
CN1802170A (zh) 2006-07-12
EP1575531A4 (en) 2008-01-23
ZA200502416B (en) 2005-10-20
CA2500189A1 (en) 2004-04-08
GEP20094699B (en) 2009-06-10
AU2003277006B2 (en) 2009-09-10
NO20052059L (no) 2005-06-27
WO2004028472A3 (en) 2006-01-19
EP1575531A2 (en) 2005-09-21
NO20052059D0 (no) 2005-04-27
AU2003277006C1 (en) 2010-04-01
PL377612A1 (pl) 2006-02-06
AU2003277006A1 (en) 2004-04-19
JP2006513990A (ja) 2006-04-27
NZ565990A (en) 2009-10-30
EP1575531B1 (en) 2011-08-17
KR20050059195A (ko) 2005-06-17
UA86749C2 (en) 2009-05-25
IS7746A (is) 2005-03-15
ATE520412T1 (de) 2011-09-15
DK1575531T3 (da) 2011-11-21
EP1575531B9 (en) 2012-02-22
RS20050255A (sr) 2007-08-03
JP2011132248A (ja) 2011-07-07
EA200500545A3 (ru) 2007-04-27
EA200500545A2 (ru) 2005-08-25
WO2004028472A2 (en) 2004-04-08
US20120058083A1 (en) 2012-03-08
JP2007039463A (ja) 2007-02-15

Similar Documents

Publication Publication Date Title
JP6807132B2 (ja) 組換えエリスロポエチンと部分的に組合されたil−1インヒビターおよびtnfアンタゴニストの貧血治療用途
JP2024105721A (ja) 炎症性疾患および自己免疫疾患の処置の組成物および方法
US20190070307A1 (en) Recombinant human epo-fc fusion proteins with prolonged half-life and enhanced erythropoietic activity in vivo
US20120058083A1 (en) Therapies for Chronic Inflammatory Demyelinating Polyneuropathy Using Interferon-Beta
WO1990006952A1 (fr) Facteur de stimulation de colonies de granulocytes modifies chimiquement
BRPI0814465B1 (pt) Proteína de fusão, dímero, método para produzir uma proteína de fusão, linhagem de célula, usos de uma proteína de fusão e de uma composição farmacêutica e composição farmacêutica
JP2014500868A (ja) 癌及び慢性感染の治療のための作動薬活性を有するil−2由来のポリペプチド
EA005005B1 (ru) ГИБРИДНЫЙ ПОЛИПЕПТИД β1α-ИНТЕРФЕРОНА ЧЕЛОВЕКА, ЕГО МУТАНТНЫЕ ФОРМЫ И ПРОИЗВОДНЫЕ И СОДЕРЖАЩАЯ ИХ ФАРМАЦЕВТИЧЕСКАЯ КОМПОЗИЦИЯ
WO1994012219A2 (en) Modified insulin-like growth factors
EP3749678A1 (en) Cell-permeable stapled peptide modules for cellular delivery
EA024507B1 (ru) Хорошо растворимые лептины
JP2023083380A (ja) インターロイキン-22の治療用誘導体
JP2022033047A (ja) 血液脳関門を越える送達のための併用療法
JP2006513990A5 (https=)
US20210268117A1 (en) Methods of generating a pegylated il-11 composition
CN114712495A (zh) 一种多功能抗体的组合物
CN114712494A (zh) 一种靶向pd-1的多功能抗体的组合物

Legal Events

Date Code Title Description
MM4A Lapse of a eurasian patent due to non-payment of renewal fees within the time limit in the following designated state(s)

Designated state(s): AM AZ BY KZ KG MD TJ TM

MM4A Lapse of a eurasian patent due to non-payment of renewal fees within the time limit in the following designated state(s)

Designated state(s): RU