DOP2019000102A - Constructos de vacuna y sus usos contra infecciones causadas por staphylococcus - Google Patents
Constructos de vacuna y sus usos contra infecciones causadas por staphylococcusInfo
- Publication number
- DOP2019000102A DOP2019000102A DO2019000102A DO2019000102A DOP2019000102A DO P2019000102 A DOP2019000102 A DO P2019000102A DO 2019000102 A DO2019000102 A DO 2019000102A DO 2019000102 A DO2019000102 A DO 2019000102A DO P2019000102 A DOP2019000102 A DO P2019000102A
- Authority
- DO
- Dominican Republic
- Prior art keywords
- staphylococcus
- infections caused
- against infections
- vaccine constructs
- uses against
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/02—Bacterial antigens
- A61K39/085—Staphylococcus
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
- C07K14/305—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Micrococcaceae (F)
- C07K14/31—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Micrococcaceae (F) from Staphylococcus (G)
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/04—Linear peptides containing only normal peptide links
- C07K7/08—Linear peptides containing only normal peptide links having 12 to 20 amino acids
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
- C12N15/62—DNA sequences coding for fusion proteins
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/74—Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
- A61K2039/52—Bacterial cells; Fungal cells; Protozoal cells
- A61K2039/522—Bacterial cells; Fungal cells; Protozoal cells avirulent or attenuated
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/55—Medicinal preparations containing antigens or antibodies characterised by the host/recipient, e.g. newborn with maternal antibodies
- A61K2039/552—Veterinary vaccine
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/20—Fusion polypeptide containing a tag with affinity for a non-protein ligand
- C07K2319/21—Fusion polypeptide containing a tag with affinity for a non-protein ligand containing a His-tag
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Genetics & Genomics (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Biomedical Technology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Molecular Biology (AREA)
- Immunology (AREA)
- General Engineering & Computer Science (AREA)
- Biotechnology (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Microbiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Plant Pathology (AREA)
- Physics & Mathematics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Oncology (AREA)
- Gastroenterology & Hepatology (AREA)
- Communicable Diseases (AREA)
- Mycology (AREA)
- Epidemiology (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
La presente invención se refiere a constructos de vacuna de fórmula (I): X-A-ligante-B-Z (I) Donde A, B, X, Z y el ligante son como se los define en la presente, los cuales son útiles contra infecciones causadas por staphulococus tales como infecciones intramamarias (IIM) en bovinos. Se proporcionan además composiciones y kits que comprenden los constructos y sus usos.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201662411120P | 2016-10-21 | 2016-10-21 |
Publications (1)
Publication Number | Publication Date |
---|---|
DOP2019000102A true DOP2019000102A (es) | 2019-07-15 |
Family
ID=62018642
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DO2019000102A DOP2019000102A (es) | 2016-10-21 | 2019-04-17 | Constructos de vacuna y sus usos contra infecciones causadas por staphylococcus |
Country Status (24)
Country | Link |
---|---|
US (2) | US11324815B2 (es) |
EP (1) | EP3529260A4 (es) |
JP (2) | JP7181208B2 (es) |
KR (1) | KR20190082229A (es) |
CN (1) | CN109843910A (es) |
AR (1) | AR109847A1 (es) |
AU (2) | AU2017346974B2 (es) |
BR (1) | BR112019007796A2 (es) |
CA (1) | CA3037070A1 (es) |
CL (1) | CL2019001048A1 (es) |
CO (1) | CO2019005169A2 (es) |
CR (1) | CR20190249A (es) |
DO (1) | DOP2019000102A (es) |
IL (1) | IL265869A (es) |
MX (2) | MX2019004539A (es) |
MY (1) | MY195369A (es) |
NZ (1) | NZ751880A (es) |
PE (1) | PE20191320A1 (es) |
PH (1) | PH12019500843A1 (es) |
RU (2) | RU2766354C2 (es) |
SG (2) | SG10201912431XA (es) |
TW (1) | TW201819402A (es) |
UY (1) | UY37448A (es) |
WO (1) | WO2018072031A1 (es) |
Families Citing this family (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2022125928A1 (en) * | 2020-12-11 | 2022-06-16 | Bayer Animal Health Gmbh | Methods and compositions for improved production of an antigen for use in an s. aureus vaccine |
Family Cites Families (16)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE3669503D1 (de) | 1985-01-07 | 1990-04-19 | Syntex Inc | Oberflaechenaktive n-(omega, omega-1-dialkoxy)- und n-(omega, omega-1-dialkenoxy)-alk-1-yl-n,n,n-trisubstituierte ammoniumverbindungen, deren herstellung und sie enthaltende pharmazeutische formulierungen. |
US6228844B1 (en) | 1991-11-12 | 2001-05-08 | Vical Incorporated | Stimulating vascular growth by administration of DNA sequences encoding VEGF |
US6380370B1 (en) * | 1997-08-14 | 2002-04-30 | Genome Therapeutics Corporation | Nucleic acid and amino acid sequences relating to Staphylococcus epidermidis for diagnostics and therapeutics |
US7060458B1 (en) | 1997-08-14 | 2006-06-13 | Wyeth | Nucleic acid and amino acid sequences relating to Staphylococcus epidermidis for diagnostics and therapeutics |
US6833134B2 (en) | 2000-06-12 | 2004-12-21 | University Of Saskacthewan | Immunization of dairy cattle with GapC protein against Streptococcus infection |
GB0107661D0 (en) | 2001-03-27 | 2001-05-16 | Chiron Spa | Staphylococcus aureus |
EP1565478B1 (en) | 2002-11-12 | 2017-08-02 | The Brigham And Women's Hospital, Inc. | Polysaccharide vaccine for staphylococcal infections |
CN1569893A (zh) | 2003-07-21 | 2005-01-26 | 中国人民解放军军事医学科学院基础医学研究所 | 金葡菌毒力因子调控蛋白的抗原表位及其模拟表位和用途 |
RU2419628C2 (ru) * | 2004-09-22 | 2011-05-27 | ГлаксоСмитКлайн Байолоджикалз с.а. | Иммуногенная композиция для применения в вакцинации против стафилококков |
AU2005333603A1 (en) * | 2004-10-21 | 2007-01-04 | Wyeth | Immunogenic compositions of Staphylococcus epidermidis polypeptide antigens |
KR100729954B1 (ko) | 2004-12-01 | 2007-06-20 | 주식회사 엘지생명과학 | Sec1 변이 단백질의 제형 및 그것의 제형화 방법 |
WO2008152447A2 (en) | 2006-10-30 | 2008-12-18 | The University Of Western Ontario | Staphylococcus aureus specific anti-infectives |
JP2012521441A (ja) * | 2009-03-23 | 2012-09-13 | エピトピックス,リミティド ライアビリティ カンパニー | ポリペプチド及びグラム陽性ポリペプチドを含有する免疫化組成物並びにこれらの使用方法 |
BRPI1013780B8 (pt) | 2009-04-14 | 2022-10-04 | Novartis Ag | Composição imunogênica útil para imunização contra staphylococcus aureus, seu método de preparação e composição farmacêutica |
SI2547361T1 (sl) | 2010-03-17 | 2021-01-29 | SOCPRA - Sceiences et Genie, s.e.c. | Bakterijske komponente cepiva iz staphylococcus aureus in njihova uporaba |
CA2839554C (en) | 2011-06-19 | 2023-09-26 | New York University | Methods of treating and preventing staphylococcus aureus infections and associated conditions |
-
2017
- 2017-10-20 CA CA3037070A patent/CA3037070A1/en active Pending
- 2017-10-20 KR KR1020197014191A patent/KR20190082229A/ko active IP Right Grant
- 2017-10-20 BR BR112019007796A patent/BR112019007796A2/pt unknown
- 2017-10-20 UY UY0001037448A patent/UY37448A/es unknown
- 2017-10-20 RU RU2019115303A patent/RU2766354C2/ru active
- 2017-10-20 CR CR20190249A patent/CR20190249A/es unknown
- 2017-10-20 SG SG10201912431XA patent/SG10201912431XA/en unknown
- 2017-10-20 EP EP17863203.0A patent/EP3529260A4/en active Pending
- 2017-10-20 CN CN201780064991.1A patent/CN109843910A/zh active Pending
- 2017-10-20 RU RU2022100889A patent/RU2022100889A/ru unknown
- 2017-10-20 SG SG11201901483QA patent/SG11201901483QA/en unknown
- 2017-10-20 PE PE2019000844A patent/PE20191320A1/es unknown
- 2017-10-20 TW TW106136089A patent/TW201819402A/zh unknown
- 2017-10-20 NZ NZ751880A patent/NZ751880A/en unknown
- 2017-10-20 US US16/337,457 patent/US11324815B2/en active Active
- 2017-10-20 AU AU2017346974A patent/AU2017346974B2/en not_active Ceased
- 2017-10-20 WO PCT/CA2017/051253 patent/WO2018072031A1/en unknown
- 2017-10-20 JP JP2019542759A patent/JP7181208B2/ja active Active
- 2017-10-20 MX MX2019004539A patent/MX2019004539A/es unknown
- 2017-10-20 AR ARP170102922A patent/AR109847A1/es unknown
- 2017-10-20 MY MYPI2019002159A patent/MY195369A/en unknown
-
2019
- 2019-04-07 IL IL265869A patent/IL265869A/en unknown
- 2019-04-16 PH PH12019500843A patent/PH12019500843A1/en unknown
- 2019-04-17 CL CL2019001048A patent/CL2019001048A1/es unknown
- 2019-04-17 DO DO2019000102A patent/DOP2019000102A/es unknown
- 2019-04-17 MX MX2023001219A patent/MX2023001219A/es unknown
- 2019-05-21 CO CONC2019/0005169A patent/CO2019005169A2/es unknown
-
2022
- 2022-04-05 US US17/713,683 patent/US20220288183A1/en active Pending
- 2022-06-28 AU AU2022204585A patent/AU2022204585A1/en not_active Abandoned
- 2022-11-16 JP JP2022183528A patent/JP2023025066A/ja not_active Withdrawn
Also Published As
Similar Documents
Publication | Publication Date | Title |
---|---|---|
CO2017013709A2 (es) | Lactamas bicíclicas. | |
DOP2016000144A (es) | Moduladores de tetrahidropiridopirazinas de gpr6 | |
DOP2017000298A (es) | Reguladores de nrf2 | |
CL2018000953A1 (es) | 2,4-dihidroxi-nicotinamidas como agonistas del receptor de apelina (apj) | |
DOP2016000145A (es) | Reguladores de nrf2 | |
UY36705A (es) | Compuestos de 4-hidroxi-3-(heteroaril)piridin-2-ona como agonistas de apj | |
DOP2016000107A (es) | PIRROLO[1,2-f][1,2,4]TRIAZINAS ÚTILES PARA TRATAR INFECCIONES POR EL VIRUS SINCITIAL RESPIRATORIO. | |
BR112017017396A2 (pt) | derivados substituídos de nucleosídeos substituídos úteis como agentes anticancerígenos | |
CO7400867A2 (es) | Modificador del sabor dulce | |
GT201400290A (es) | Carboxamidas heterociclicas fungicidas | |
CR20170336A (es) | Compuestos de azolina sustituidos con un sistema de anillos condensados | |
BR112017013767A2 (pt) | uso de picolinamidas como fungicidas | |
BR112017027147A2 (pt) | agente estimulante de restauração/crescimento de cabelo | |
CL2019001736A1 (es) | Polimorfos. | |
ECSP18012103A (es) | Inhibidores del receptor del factor estimulador de colonias 1 (csf-1r) | |
CL2019001737A1 (es) | Polimorfos. | |
CO2017006969A2 (es) | Compuestos cíclicos sustituidos con un sistema de anillos condensado | |
UY35305A (es) | Compuestos sustituidos como moduladores de la pro teína de activación de la 5-lipoxigenasa (flap) | |
CO2018004581A2 (es) | Compuestos de criptoficina y productos conjugados, y sus métodos de preparación | |
UY38031A (es) | Hidroxiisoxazolinas y derivados de estos | |
CO2018007663A2 (es) | Compuestos indolinonas y su uso en el tratamiento de enfermedades fibróticas | |
CR20160397A (es) | Pirazoles para el control de plagas de invertebrados | |
ECSP16074207A (es) | Pirazinas moduladoras de gpr6 | |
NI202000042A (es) | Polimorfos | |
CR20180254A (es) | Compuestos de imino con un sustituyente de 2-cloropirimidin-5-ilo como agentes de control de plagas |